No improvement in symptom severity or quality of life seen with vitamin D supplementation in irritable bowel syndrome
FRIDAY, Aug. 6, 2021 (HealthDay News) — For patients with irritable bowel syndrome (IBS), vitamin D supplementation has no impact on improving symptom severity or quality of life, according to a study published online July 30 in the European Journal of Nutrition.
Claire E. Williams, from the University of Sheffield in the United Kingdom, and colleagues examined whether vitamin D supplementation improves IBS symptoms in a randomized, double-blind, placebo-controlled trial. A total of 135 participants from the community received vitamin D or placebo for 12 weeks.
At baseline, 60 percent of the participants had deficient or insufficient vitamin D. The researchers observed an increase in vitamin D levels in the intervention arm versus the placebo arm (45.1 Â± 32.88 nmol/L versus 3.1 Â± 26.15 nmol/L; P < 0.001). However, no difference was seen in the change in IBS symptom severity over time between the intervention and placebo arms (â62.5 Â± 91.57 versus â75.2 Â± 84.35; P = 0.426). Similarly, no difference was seen in the change in quality of life between the intervention and placebo trial arms (â7.7 Â± 25.36 versus â11.3 Â± 25.02; P = 0.427).
“This study found no benefit of vitamin D supplementation on either symptoms of IBS or on quality of life measures using standardized assessments,” the authors write. “Notwithstanding any benefit of vitamin D on IBS symptomology, IBS patients should be screened for vitamin D status and supplemented appropriately for general health reasons.”
The study was partially funded by BetterYou Ltd., which supplied the vitamin D supplements.
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