Home News General Health News Traumatic Brain Injury Ups Risk for Future Stroke

Traumatic Brain Injury Ups Risk for Future Stroke

Findings show highest risk in the first four months post-TBI, but risk remains regardless of severity or type of injury

WEDNESDAY, April 21, 2021 (HealthDay News) — Traumatic brain injury (TBI) is an independent risk factor for stroke, according to a review published online April 4 in the International Journal of Stroke.

Grace M. Turner, Ph.D., from the University of Birmingham in the United Kingdom, and colleagues conducted a systematic literature review to examine the association between TBI and stroke risk.

Based on 18 included studies (2,606,379 participants from four countries), the researchers found that TBI patients had a significantly increased risk for stroke versus controls (pooled hazard ratio, 1.86). Stroke risk may be highest in the first four months post-TBI but can remain significantly elevated up to five years post-TBI. Regardless of severity or subtype of TBI, increased stroke risk remains. Post-TBI, the risk for stroke may be reduced with vitamin K antagonists and statins but may be higher with certain classes of antidepressants.

“This initial four-month period should also be used by clinicians to administer stroke prevention medication and lifestyle advice to mitigate the excess risk of stroke associated with TBI,” Turner said in a statement.

Two authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text

Copyright © 2021 HealthDay. All rights reserved.