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Migraine History Tied to More Severe Menopause Symptoms

Increased odds of severe or very severe hot flashes seen in women with history of migraine

WEDNESDAY, Sept. 22, 2021 (HealthDay News) — A history of migraine is associated with higher severity of menopause symptoms, according to a study presented at the annual meeting of the North American Menopause Society, held from Sept. 22 to 25 in Washington, D.C.

Stephanie Faubion, M.D., from the Mayo Clinic in Jacksonville, Florida, and colleagues examined the potential link between a history of migraine and vasomotor symptoms (VMS). The analysis included data from 3,308 women (aged 45 to 60 years) participating in the Data Registry on the Experiences of Aging, Menopause, and Sexuality.

The researchers found that women with a history of migraine had significantly higher total Menopause Rating Scale (MRS) scores and were more likely to have severe/very severe hot flashes versus no hot flashes (odds ratio, 1.40) versus women without migraine history. There was a monotonical increase in the odds of reporting more severe hot flashes among women with a history of migraine. Women with low back pain had higher MRS scores, but were no more likely to have severe/very severe hot flashes versus those without back pain.

“We believe that neurovascular dysregulation may explain the link between migraines and hot flashes,” Faubion said in a statement. “Given the high prevalence of migraine in women, this association may help identify women who are at risk for more severe hot flashes in midlife.”

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