BinaxNOW Rapid Antigen Test Has Lower Sensitivity Than RT-PCR
Sensitivity 64.2 and 35.8 percent for specimens from symptomatic and asymptomatic persons, with near 100 percent specificity
For COVID-19 ICU Patients, Death Linked to COVID-19 ICU Strain
Mortality increased when COVID-19 ICU demand was >75 to 100 percent for patients treated in COVID-19 ICU
Rates of Suicide, Suicide Attempts Up for Individuals With Autism
More than 90 percent of those with ASD with suicide attempt, suicide had another comorbid condition
Tool Can Predict Chemo Toxicity for Seniors With Breast Cancer
Score has been developed and validated that includes eight independent predictors of grade 3 to 5 chemotherapy toxicity
Nearly One in Four Doctors Report Harassment on Social Media
No gender difference seen in personal attacks; women significantly more likely to report online sexual harassment
Rachel Levine Nominated as U.S. Assistant Health Secretary
Levine is secretary of health for Pennsylvania and is currently leading the state's response to the COVID-19 pandemic
Default Opt-Out of Cardiac Rehabilitation Increases Referrals
Redesign of decision pathways from opt-in to opt-out results in increase in referrals for cardiac rehabilitation
Myopia Up in Children Confined to Home During Pandemic
Substantial myopic shift and increased prevalence of myopia seen among children aged 6, 7, 8 years
Improving Access to After-Hours Primary Care Cuts ED Visits
Incentivizing physicians to improve access to after-hours care reduces some less-urgent visits to emergency department
Steps Outlined to Reduce Postop Delirium in Older Adults
Anesthesiologists play key role on multidisciplinary team to optimize perioperative brain health in older adults
Routine Use of Antibiotics After Sinus Surgery Questioned
Small randomized trial shows similar infection rates, more diarrhea with antibiotic versus placebo after endoscopic sinus surgery
1999 to 2018 Saw Decrease in Cancer-Related Suicide
Largest decreases seen among high-risk populations, including men, older patients, patients with prostate and lung cancer
Estrogen Therapy Need Not Stop for Gender-Affirming Surgery
Authors find that perioperative venous thromboembolism rarely occurs, regardless of suspension of hormone therapy prior to surgery
IgG Level in Convalescent Plasma Affects COVID-19 Death Risk
Risk for death reduced with higher versus lower levels of anti-SARS-CoV-2 IgG, but only in patients not receiving mechanical ventilation
COVID-19 Vaccine Likely Safe for Lactating Women
However, Academy of Breastfeeding Medicine calls for lactating women to be included in trials
Many Parents Support Peer Mental Health Programs at Schools
Majority of parents say peers would understand teens' problems better than adults
USPSTF Affirms Evidence-Based Methods for Smoking Cessation
Behavioral and pharmacotherapy interventions, alone or in combination, recommended; evidence insufficient for e-cigarettes
Virtual Care Maintains Quality Cancer Care
Majority of patients, physicians report satisfaction with virtual care
Expert Panel Criticizes WHO, China for Pandemic Response
Panel finds there were 'lost opportunities' to establish basic public health measures early in the pandemic
California First State With Over 3 Million COVID-19 Cases
Biden administration has said it will not be lifting restrictions on international travel
Smokers More Likely to Report Symptoms Suggestive of COVID-19
Current smokers have increased risk for reporting classic symptoms, more than five symptoms, more than 10 symptoms
One-Third of U.S. Adults Likely to Refuse a COVID-19 Vaccine
Blacks, women, and conservatives more hesitant in the United States
Stem Cell Infusions Investigated for Treatment of COVID-19 ARDS
Researchers explore possible anti-inflammatory effects of mesenchymal stem cells in COVID-19 acute respiratory distress syndrome
Higher Dietary Fiber Lowers Premenopausal Depression Risk
Significant association between dietary fiber intake and prevalence of depression seen for premenopausal, but not postmenopausal, women
Stopping RAS Inhibitors May Worsen Outcomes in CKD
Stopping therapy tied to lower risk for dialysis, but higher risk for cardiovascular events and death
Physician’s Briefing Weekly Coronavirus Roundup
Bupropion-Naltrexone Bests Placebo in Methamphetamine Use Disorder
Response was low but higher with naltrexone-bupropion than placebo during 12-week, two-stage trial
Breast, Cervical, CRC Screening Below Healthy People 2020 Targets
Colorectal cancer test receipt near target in 2018, with 66.9 percent of adults aged 50 to 75 years up to date with testing
Cardiorespiratory Fitness Linked to Psoriasis, Psoriatic Arthritis
Significant association found between low cardiorespiratory fitness at mean age of 18.3 years and psoriasis, psoriatic arthritis among men
Life Expectancy Reduced Considerably Due to COVID-19
Life expectancy at birth reduced by 1.13 years to 77.48 years; reductions greater for Blacks, Latinos versus Whites
Repeat Postvasectomy Semen Analyses Down Under New Guidelines
Men in postguideline cohort had lower risk for requiring any repeat postvasectomy semen analysis
Primary Care-Recorded Mental Illness Decreased During COVID-19
Reductions seen in incidence of primary care-recorded depression, anxiety disorders, first antidepressant prescribing in United Kingdom
Memory Preserved in Rare Aphasia Tied to Alzheimer Disease
Decline in language function, but not episodic memory, seen for primary progressive aphasia associated with Alzheimer disease
Previous COVID-19 Infection May Confer Immunity for at Least Five Months
Team from Public Health England analyzed data from months of regular testing of health care workers
Referrals for Acute Heart Failure Dropped During COVID-19
Referrals to acute heart failure team decreased; corresponding increase seen in 30-day case fatality rate
Women Forgoing Reconstruction After Mastectomy Pleased
22 percent experienced 'flat denial,' when the option of no reconstruction after mastectomy was not initially offered
More Diabetes Remission in T2DM Seen With Low-Carb Diets for Six Months
Large clinically important improvements observed in weight loss, triglycerides, and insulin sensitivity, which decreased at 12 months
Drop in ED Visits for Cardiac Conditions Tied to Later Cardiac Deaths
Undertreatment of cardiac conditions during COVID-19 pandemic tied to delayed excess mortality versus previous years
CDC Describes COVID-19 Trends in Nursing Home Residents, Staff
Rates of COVID-19 increased during June and July, followed by decline through mid-September, increase by late November
College Campuses at Risk for Extreme Incidence of COVID-19
Colleges rapidly reduced the number of new infections, but many failed to control the spread beyond the campus
Cochlear Implants Aid Speech Recognition in Most Adults
However, individual benefit shows large degree of variability
Multifocal Microvascular Injury ID’d in Brain in COVID-19
No SARS-CoV-2 detected in postmortem samples, but brain may be susceptible to microvascular damage
Incidence of COVID-19 Increased in Children Since September
Trends for children tracked consistently with those of adults; incidence lower for children aged 0 to 10 years
Greater Levels of Exercise May Protect Brain in Later Life
Greater levels of moderate- to vigorous-intensity physical activity linked to more intact white matter integrity in late life, lower odds of lacunar infarcts
Mental Health Disorders Common Among ICU Staff During COVID-19
45 percent of respondents met threshold for probable clinical significance on measures of depression, PTSD, anxiety, problem drinking
Exercise Key to Lowering Risk for Gestational Diabetes
However, authors say amount of exercise needed may be more than current recommendations
U.S. COVID-19 Vaccine Rollout Nears 1 Million Doses Per Day
News comes as Ohio State University researchers discover new variant of COVID-19 virus
WHO Experts Finally Arrive in Wuhan for COVID-19 Investigation
First known cases of the novel coronavirus appeared in the city more than a year ago
Causal Link Suggested for Smoking, Subarachnoid Hemorrhage
Genetic susceptibility to smoking, assessed using polygenic risk score, is associated with increased risk for SAH
Inhaled Treprostinil Beneficial in Pulmonary Hypertension
Exercise capacity improved, clinical worsening reduced for patients with pulmonary HTN due to interstitial lung disease
Symptom-to-Balloon Time Linked to Infarct Size in STEMI
Patients with long versus short SBT exhibit greater microvascular obstruction; no association seen by door-to-balloon time
Lethal Means Counseling, Cable Locks Promote Safe Firearm Storage
Lethal means counseling outperformed control at six months; cable locks outperformed control at three, six months
Higher Hb Threshold for Transfusion Not Better for Preemies
Use of a higher hemoglobin threshold for transfusion in anemic preterm infants does not lower risk for death, neurodevelopmental impairment
Treatment Plans, Outcomes Better for Women With ACS and Low-Risk HEART Score
Women may receive more appropriate care than men with use of History, Electrocardiogram, Age, Risk factors, and Troponin (HEART) score
Risk for Developing, Dying From Second Cancer Higher for Survivors
Adult-onset cancer survivors have greater risk for subsequent primary cancer; majority of these incidences are cancers associated with obesity or smoking
Practice’s Bariatric Nonsurgical Visits Up With Telehealth During Pandemic
Follow-up visits increased for nonsurgical providers; however, new patient and follow-up surgical visits did decrease
Ad26.COV2-S Vaccine Seems Safe, Immunogenic for SARS-CoV-2
Neutralizing antibodies detected in 90 percent or more of all participants on day 29 after the first vaccine dose
Negative COVID-19 Test to Be Required for People Flying to U.S.
Passengers without proof of a negative test will not be allowed to board flights to America
Women Must Get Abortion Pill in Person: U.S. Supreme Court
Similar in-person rules for other medications have been suspended during the pandemic
Neonatal Abstinence Syndrome, Maternal Opioid-Related Diagnoses Up
Estimated rates of NAS, maternal opioid-related diagnoses increased from 2010 to 2017 in the U.S., with variation between states
COVID-19 Vaccine Recommended for All Americans Over 65
Health officials also recommended COVID-19 vaccines be given to all adults with preexisting conditions
Pregnancy Outcomes Examined for Women With Multiple Sclerosis
Women with pregnancy after versus before MS diagnosis have fewer children, at older age, with increased odds of C-section
Cognitive Performance During Menopause Transition Examined
Longitudinal declines seen in measures of learning, memory, attention/working memory domains in low-income women of color
Consuming Alcohol May Increase Risk for Atrial Fibrillation
Hazard ratio 1.16 for one drink per day; similar associations seen across types of alcohol
DKA Common in Blacks With T1DM and Confirmed COVID-19
Non-Hispanic Blacks with T1DM and COVID-19 have nearly fourfold increased odds of presenting with diabetic ketoacidosis
CVD Risk Lowest at Highest Level of Physical Activity
Risk for cardiovascular disease decreases as accelerometer-measured moderate, vigorous, and total physical activity levels increase
Higher Coffee Intake May Reduce Risk for Prostate Cancer
Pooled relative risk of 0.988 for each increment of one cup of coffee per day revealed in meta-analysis of cohort studies
Few Ob-Gyns Can Prescribe Buprenorphine for Opioid Use
Obstetrician-gynecologists able to prescribe buprenorphine more likely located in the suburbs
Better Hospital Nurse Staffing Tied to Fewer Sepsis Deaths
Staffing more strongly tied to deaths than adherence to mandated sepsis care bundles
Saliva, Nasopharyngeal Samples Equally Sensitive for SARS-CoV-2
Incremental cost of $8,093 per additional detection found with nasopharyngeal swab among individuals without previous SARS-CoV-2
Experimental Drug for Alzheimer Disease Shows Promise
After six to 12 months of treatment with the drug, patients no longer had amyloid protein plaques
Financial Toxicity Linked to QOL After Breast Cancer Surgery
Strongest correlation seen for BREAST-Q psychosocial well-being, with 0.89 change per unit change in financial toxicity score
Overall Cancer Death Rates Decreased From 1991 to 2018
Pace of annual decline in lung cancer mortality increased from 2009-2013 to 2014-2018 for men, women, overall
Disneyland to Be Mass COVID-19 Vaccination Site
California's Orange County plans to open more 'Super Point-of-Dispensing' sites soon
Ischemic Heart, Hypertensive Disease Deaths Up During COVID-19
Second study shows reduction in cardiovascular diagnostic testing across the world during pandemic
WHO and Partners to Stockpile Ebola Vaccine
Emergency reserve of about 500,000 doses of a Merck vaccine will be established
Flat, Flexible No Better Than Stable, Supportive Shoes for Knee OA
Change in pain, but not function, favoring stable, supportive shoes over flat, flexible shoes in knee osteoarthritis
More Infectious COVID-19 Variant Now Seen in Nine States
A South African variant that is also more contagious has not been detected in the United States yet
Link Between T. gondii Infection, Glioma Risk Examined
Significant increase in glioma risk seen for those with higher antibody titers to the sag-1 antigen
Albuminuria Down in Adults With Newly Diagnosed T2DM
Improvements seen in glycemic, blood pressure, lipid control within the population partly explain decrease in albuminuria
Composition of Gut Microbiome Altered in Patients With COVID-19
Several gut commensals with known immunomodulatory potential underrepresented in patients with COVID-19
Three-Quarters of U.S. Adults Likely to Get COVID-19 Vaccine
However, lower education, income, and perceived threat of COVID-19 tied to lower likelihood
Hydroxychloroquine Level Tied to Thrombosis Risk in Lupus
Rate of thrombotic events lower for patients with mean HCQ blood levels >1,068 versus <648 ng/mL
Colorectal Cancer Risk From Obesity Varies by Sex
Authors say more nuanced approach needed to understand link between body weight and risk for colorectal cancer
Autism May Raise Risk for Substance Use Disorder
Risk for SUD lower for subgroups of individuals with ASD receiving one or multiple psychotropic agents
Pediatric Hospitalization for COVID-19 Increasing Across States
Rates at beginning and end of study and extent of change in rates significantly vary across states
Maintaining Exercise During Pandemic Aids Prenatal Mental Health
Findings based on an online survey of more than 1,800 pregnant women
Treatment Success Seen With Antibiotics for Uncomplicated Appendicitis
Seven days of oral antibiotics noninferior to two days of intravenous followed by oral antibiotics
FUS Subthalamotomy Studied in Asymmetric Parkinson Disease
Motor features improved with focused ultrasound subthalamotomy on the side opposite main motor symptoms
One in Four Women With ADHD Attempts Suicide
Women with ADHD and childhood adversities and adults with substance dependence, depression particularly vulnerable
WHO Experts Arrive in China Thursday to Probe COVID-19 Origins
China has stalled on admitting the independent group of WHO experts into the country
Two Billion COVID-19 Vaccine Doses From BioNTech Expected This Year
Company also looking to widen eligibility for the vaccine to include pregnant women, children, and others
Symptoms Persist in Many Discharged COVID-19 Patients
Most common symptoms at six months were fatigue or muscle weakness, sleep difficulties, anxiety or depression
Timing, Intensity of Oral Sex Are Risk Factors for HPV-OPC
Increased odds of human papillomavirus oropharyngeal cancer seen for younger age at first oral sex, oral sex intensity
Trying Multiple Tobacco Products in Teens Tied to Later Daily Smoking
Electronic cigarette use increases the risk for later daily cigarette smoking more than threefold
Food Insecurity Increasing Among Older U.S. Adults
Food insecurity also tied to lower-quality diet in older adults
Early High-Titer Plasma Reduces Progression of COVID-19
Early administration of high-titer convalescent plasma against SARS-CoV-2 reduces progression in mildly ill older adults
Trauma Centers Made New Processes for Optimal Care During COVID-19 Pandemic
Most hospitals designated more beds to the intensive care unit; 50 percent designated an ICU for COVID-19 patients
Drive-Through IOP Screening Clinic Feasible During COVID-19
Intraocular pressure screening clinic allows for continued management, including necessary changes in management
Physician’s Briefing Weekly Coronavirus Roundup
Post-Hip Fracture Mortality Higher in Patients Living Alone
Findings independent of age, education level, number of children, and degree of urbanization
Biden Says He Will Release All Vaccine Doses After Taking Office
The potentially risky move is meant to boost a nationwide COVID-19 vaccination program that has gotten off to a slow start
Laws Promoting Flu Shot for Hospital Workers Can Cut Deaths
2.5 percent drop seen in monthly pneumonia, flu mortality rates with implementation of state laws requiring hospitals to offer flu shot
Affordable Care Act Reduced Income Inequality in United States
Income inequality reduced within and across groups based on race/ethnicity, age, family educational attainment
Virtual Kidney Transplant Evaluation Possible
Telehealth platform enabled maintenance of wait-list evaluation volume in large kidney transplant program during COVID-19 pandemic
Vaccine Rollout Slows as Many Health Care Workers Balk at Shots
In nursing homes and to some degree in hospitals, employees are refusing shots, expressing fears of side effects
Firearm Use Up in Female Nurse Suicides in the U.S.
Female nurses used firearms in suicides less often than other women from 2003 to 2013, but firearm use increased from 2014 to 2017
Moderna COVID-19 Vaccine Protection May Last Years, Company Claims
CDC recommends people who have already had the virus also receive the vaccine as reinfection is possible
Many Dialysis Patients Report Proficiency in Mobile Health
Older patients have lower mobile health proficiency, as do those with Hispanic/Latinx ethnicity, less than college education
Perception of Not Returning to Full Health Common After COVID-19
47 percent experience fatigue, with no correlation between any measures of persistent disease and initial disease severity
Guidance Provided for Management of Pediatric Eating Disorders
Pediatricians should initiate comprehensive evaluations, including medical, psych assessment; refer to multidisciplinary care
Review Confirms Interarm SBP Difference, Mortality Link
All-cause mortality risk increased with interarm systolic blood pressure difference magnitude from ≥5 mm Hg threshold
Predicted Heart Age Higher Among Cancer Survivors
Excess heart age 8.5 years for men and 6.5 years for women; varies by age, race/ethnicity, education, income
Majority of SARS-CoV-2 Transmission Due to Asymptomatic Individuals
In base case of modeling study, 59 percent of transmission attributed to presymptomatic and asymptomatic individuals
Mental Well-Being Worse for Men From Ethnic Minorities During Pandemic
Greater average increase in mental distress during COVID-19 seen for women and for Black, Asian, minority ethnic versus White British men
Vitamins E, C Inversely Linked to Risk for Parkinson Disease
Comparing individuals in highest versus lowest tertile of exposure, inverse link seen for both vitamins C and E; no link for beta-carotene, NEAC
PCPs Spend Average of 18 Minutes With Each Patient
Shorter scheduled appointments tend to run over more often versus longer appointments
Statins May Protect Heart From Chemo for Early Breast Cancer
Risk for heart failure hospital presentations significantly lower in statin-exposed women treated with anthracyclines
NFL Urges Teams to Offer Stadiums as Vaccination Centers
NFL would benefit from Americans being vaccinated because it increases the odds that state officials will reopen stadiums
Red Cross Issues Call for More Blood Plasma to Treat COVID-19 Patients
People who have recovered from COVID-19 may have antibodies in their plasma that could boost immunity in current patients
Allergists Affirm Safety of COVID-19 Vaccines for Most
All patients should be observed for 15 minutes after vaccination; staff should be trained in anaphylaxis management
Sitagliptin Promising Addition for Preventing Acute GVHD
Low incidence of grade II to IV acute GVHD seen in patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation
Mindfulness-Based Cognitive Therapy Aids Depressive Disorder
MBCT tied to significant improvement in Reassure self and significant reduction in Inadequate self
Teen Vaping Doubles Risk for Subsequent Tobacco Use
Adolescent boys who use e-cigarettes twice as likely to initiate cigarettes, smokeless tobacco products
Machine Learning Models Can Predict Gestational Diabetes
Effective discrimination achieved with 73-variable model, seven-variable logistic regression model in early pregnancy
Rehospitalization Down With Remote Monitoring After Arthroplasty
Findings show significant reduction in rehospitalization rate for patients undergoing hip or knee arthroplasty
11.1 Anaphylaxis Cases/Million Doses of Pfizer-BioNTech COVID-19 Vaccine Reported
Median interval from vaccine receipt to symptom onset was 13 minutes
Number of U.S. Adults Willing to Take COVID-19 Vaccine Down
Findings based on a biweekly survey conducted from April through December
Two-Thirds of Lupus Patients Likely to Take COVID-19 Vaccine
However, national survey uncovered racial differences in uptake, safety concerns
Cow’s Milk Intake While Breastfeeding May Cut Child Food Allergies
Findings based on food allergies diagnosed in offspring by age 12 months
Postpartum Trajectory Differs by Race After Hypertensive Disorders of Pregnancy
At six weeks postpartum, 68 percent of Black women and 51 percent of White women meet hypertension criteria
Age at Vasectomy Reversal Not Tied to Achieving Pregnancy
Shorter obstructive interval and female age associated with achieving pregnancy
Pandemic-Related MMR Vaccine Decline Persists
Authors say catch-up strategies are necessary to ensure young children receive preventive care
Mindfulness Training Does Not Reduce Migraine Frequency
However, mindfulness-based stress reduction improves various measures, including disability and quality of life
Pulse Oximeter Readings May Be Inaccurate in Black Patients
Blacks more likely than Whites to have oxygen saturation of less than 88 percent on arterial blood gas while 92 to 96 percent on pulse oximetry
eGFR Variability Linked to All-Cause Mortality Risk
No association seen for estimated glomerular filtration rate variability and cardiovascular disease events
Some Hospitalized Heart Patients Report Frequent Nightmares
Frequent nightmares associated with depression, anxiety, insomnia but not cardiovascular medications, sleep-disordered breathing
AAP Outlines Principles Guiding School COVID-19 Policies
Academy says opening schools generally does not significantly increase community transmission, but mirrors community transmission
Vast Majority of Mild COVID-19 Patients Lose Sense of Smell
Nearly one-quarter of affected patients report lack of recovery at 60 days
Psychological Distress Increased in U.S. During COVID-19
Numbers of people who experienced serious psychological distress over 30 days during pandemic similar to that in entire year prior to pandemic
China Delays Allowing Experts to Study Start of Pandemic
Experts are expected to visit the city of Wuhan, where it is believed COVID-19 first emerged
Drug Makers Raise Prices on 500 Prescription Drugs
AbbVie, Bristol Myers Squibb, GlaxoSmithKline, and Pfizer among companies raising their prices by a median of 4.6 percent
Single-Drug Regimen Now Advised for Uncomplicated Gonorrhea
Single 500-mg intramuscular dose of ceftriaxone recommended for uncomplicated urogenital, anorectal, pharyngeal gonorrhea
~14.3 Percent of U.S. Population Infected With SARS-CoV-2 by Nov. 15
Estimated medians of 46,910,006 SARS-CoV-2 infections, 956,174 hospitalizations, 304,915 deaths reported by mid-November
Top FDA Officials Say Two Full Doses of COVID-19 Vaccines a Must
Agency says it is understandable that people may want to stretch the vaccine supply, but it is not safe to do so
Lifestyle Factors Linked to GERD Risk in Women
Nearly 40 percent of gastroesophageal reflux disease symptoms could be prevented by adherence to five lifestyle factors
Euglycemic DKA ID’d in T2DM Patients With COVID-19
Five cases of euDKA identified in patients with type 2 diabetes using SGLT2 inhibitors who developed SARS-CoV-2 infection
Some Transmission of SARS-CoV-2 Occurs After Seven, 10 Days
81 percent chance that a contact who was negative for SARS-CoV-2 and asymptomatic through seven days would remain so at 14 days
Bone Quality Linked to Complications After Spinal Fusion
Patients who developed complications had lower trabecular vBMD, fewer and thinner trabeculae at radius and tibia
Los Angeles EMS Told to Not Transport Patients Deemed Likely to Die
L.A. County Emergency Medical Services Agency also told EMS workers to give less oxygen to patients
Child Physical Abuse Encounters Declined During COVID-19
Declines occurred during period when total volume of encounters was also lower; severity of encounters unchanged versus previous years
Intradialytic Hypotension Tied to Peripheral Artery Disease
Findings based on large, national study of more than 45,000 hemodialysis patients
Mental Health Consequences of COVID-19 ID’d Across Populations
Health care workers have higher prevalence of insomnia; however, mental health problems seen across countries, gender
U.S. Health Care Spending Increased 4.6 Percent in 2019
Growth rate similar to that experienced in 2018 and consistent with growth rate since 2016
Pandemic Has Disrupted Lung Cancer Screenings
Once operations resumed, decrease seen in new patients screened, proportion of suspicious nodules increased
Fitness Apps, Trackers Boost Physical Activity
Among adults without chronic disease, apps and trackers may boost activity by 1,850 steps per day
NIDA: Teen Vaping Levels Seem to Have Plateaued in 2020
Percentage of teenagers in eighth, 10th, 12th grade vaping nicotine and marijuana remained stable from 2019 to 2020
Polygenic Risk Scores May Improve IBD Risk Prediction
For every population in BioMe biobank, combining risk scores from distinct ancestral populations improved risk prediction for IBD
Jaw Osteonecrosis Tied to Treatment for Bone Metastases
Cancer type, oral health, and frequency of dosing for zoledronic acid linked to risk for osteonecrosis of the jaw
Factors ID’d for Mortality in Nursing Home Residents With COVID-19
Increased age, male sex, impaired cognitive and physical function associated with increased odds of 30-day mortality
Few Adults Report Having Firearm Safety Discussions With Doctors
7.5 percent of respondents report having ever discussed firearm safety; 12 percent among those living with children
Suicide Risk Higher Among Patients With Parkinson Disease
Increased risk not fully explained by higher rates of mental disorders
U.S. COVID-19 Vaccine Rollout Struggling
Scientists are considering ways to speed distribution and uptake of the vaccine
Britain to Try Mix-and-Match COVID-19 Vaccinations
In the United States, the CDC has said that COVID-19 vaccines 'are not interchangeable'
mRNA-1273 Vaccine Highly Effective for Preventing COVID-19
Published data on Moderna vaccine show severe COVID-19 in 30 individuals -- all in the placebo group -- in trial of 30,420 participants
Hypertensive Disorders of Pregnancy Have Lasting Cognitive Impact
Women with gestational hypertension perform significantly worse on 15-word learning test than those with normotensive pregnancy
Odds of Anxiety, Depression, ADHD Up With Congenital Heart Disease
Youth with CHD have increased odds of anxiety and/or depression, ADHD, regardless of CHD severity
CVD Biomarker Levels Up for Dual Use of E-Cigarettes, Cigarettes
Levels of biomarkers of inflammation, oxidative stress similar for dual users and exclusive cigarette users
Autistic Traits ID’d in Carriers of CNVs Linked to Autism
54 percent of carriers of certain copy number variants have elevated levels of autistic traits
No Causal Link Found for COVID-19, Guillain-Barré Syndrome
Incidence of GBS decreased between March and May 2020 compared with same months of 2016 to 2019
In Cirrhosis, Women Have Worse Frailty Scores Than Men
Frailty mediated an estimated 13 percent of the gender gap in wait-list mortality among those awaiting liver transplant
2014 to 2019 Saw Drop in Oncologists Accepting Industry Payments
Annual per-physician payment value decreased for those receiving less than $10,000, increased for those receiving more than $10,000
New Mammogram-Based Measures Improve Breast Cancer Prediction
For screen-detected, younger-diagnosis breast cancers, best-fitting models include new measures based on brightness, texture
First Known U.S. Case of New Variant of COVID-19 Seen in Colorado
Variant is thought to be more contagious -- but not more lethal -- than variants previously circulating this year
Physician’s Briefing Weekly Coronavirus Roundup
Cardiovascular Risk Up With Metabolic Syndrome in Psoriasis
After adjustment for all metabolic syndrome factors, blood pressure, waist circumference linked to noncalcified coronary burden
USDA, HHS Update Dietary Guidelines for Americans
2020 to 2025 guidelines recommend customizing nutrient-dense food and beverage choices to reflect personal preference, cultural traditions
Secondary Bloodstream Infections Tied to Poorer COVID-19 Outcomes
Altered mental status, ICU admission, higher in-hospital mortality more likely in hospitalized patients with severe COVID-19 and sBSI
E-Cigarettes as Consumer Devices May Not Improve Smoking Cessation
In randomized clinical trials, e-cigarette use linked to more quitting for smokers provided e-cigarettes versus conventional therapy
Gaps Found in Opioid Use Disorder Treatment During Pandemic
Percentage of patients receiving at least one urine test lower in March through May of 2020 versus 2019
Ongoing Exposure to Stressors Harms Health
So-called allostatic load increases with age but increases more sharply among Black, Latino populations
Dexamethasone Not Favored for Chronic Subdural Hematoma
Dexamethasone worse than placebo with respect to favorable outcome at six months
More Dangerous Mouthwashes and Hand Sanitizers Recalled
Hand sanitizer recall due to presence of methanol; oral rinse recall due to possible contamination with bacteria
Bariatric Surgery Patients Not Getting Recommended Follow-Up Care
Annual proportions of patients receiving blood tests specific to bariatric surgery, prescription nutritional supplements low
U.K. Is First Country to Approve Oxford-AstraZeneca COVID-19 Vaccine
Vaccine could become the dominant form of inoculation because at $3 to $4 a dose, it is a fraction of the cost of other vaccines
Appetite-Regulating Hormones Lower After Sucrose Versus Glucose
Increases in glucose, insulin, GLP-1, PYY less robust with sucrose versus glucose ingestion; increases in glucose, PYY smaller in obese adults
Donor Kidney Biopsies Do Not Aid Transplant Outcome Prediction
Adding donor histology did not significantly improve prediction of long-term allograft failure in recipients at French, Belgian centers
Glycemic Control in Type 1 Diabetes Improved During Lockdown
Decrease in alcohol consumption, easier diabetes control perception were factors associated with better glycemic control
Altered Mentation, Stroke Up COVID-19 In-Hospital Mortality
Findings revealed by comparison to matched hospitalized COVID-19 patients without neurological involvement
Timing of Antimicrobial Prophylaxis Examined for C-Section
Risk for surgical site infection not increased for surgical antimicrobial prophylaxis after cord clamping versus before incision
Anticoagulants Not Tied to Higher Risk for GI Bleed in COVID-19
3 percent of hospitalized COVID-19 patients experience gastrointestinal bleeding
Oral Azacitidine Benefits Some Older Adults With AML
Overall, relapse-free survival prolonged among older patients in first remission after chemo who receive CC-486 versus placebo
Head and Neck Cancer Surgery Seems Safe During COVID-19
Links seen for severe pulmonary complications in COVID-19-positive patients with advanced tumor stage, critical care admission
Inequities Seen in Accessing Telemedicine During COVID-19
Factors linked to fewer completed telemedicine visits include older age, Asian race, non-English as preferred language, Medicaid insurance
Primary Aldosteronism Testing Rare in Treatment-Resistant HTN
Testing correlated with increased likelihood of initiation of MRA therapy and with better BP control over time
Knee Osteoarthritis Symptoms Improved With Stepped Care
Veterans experience modest improvements with stepped exercise program versus arthritis education control
Incidence of Dislocation After Hip Arthroplasty May Be Higher Than Thought
Age, sex, head size, fixation method, and surgical approach independently associated with dislocation risk
Seizure Frequency Not Up in Pregnancy for Women With Epilepsy
Changes in doses of antiepileptic drugs occurred more often in pregnant women than in nonpregnant controls
Another COVID-19 Vaccine Candidate Begins Final Clinical Trials
Novavax vaccine needs only standard refrigeration, not freezing or ultracold temperature storage
One in Four Older Adults Have Used Emergency Dept in Past Few Years
Cost of emergency care is major concern among most older adults