Federal Data Understated COVID-19 Cases, Deaths in Nursing Homes

Estimated cases and deaths omitted represented 11.6 and 14.0 percent of cases and deaths in nursing home residents in 2020

Road Traffic, Railway Noise Linked to Increased Dementia Risk

General pattern showed higher hazard ratios with higher noise exposure, with levelling off or decline at higher noise levels

Peanut Consumption Linked to Reduced Stroke Risk in Japan

Association seen in men and women for higher peanut consumption with reduced risks of total stroke, ischemic stroke, cardiovascular disease

Mental Health Improved Following First Dose of COVID-19 Vaccine

Adults receiving the vaccine between December 2020 and March 2021 reported decreased mental distress following first dose

Rehospitalization Increased With Delayed Home Health Care in Diabetes

Racial/ethnic-minority patients are less likely to receive services within 14 days after discharge to home health care

SARS-CoV-2-Positive Household Members Up Infection Risk for HCWs

Exposure to positive household members linked to increased risk for infection for vaccinated health care workers

Racial, Ethnic Disparities Seen for Severe Flu-Associated Disease

Disparities existed across the age spectrum and across 10 flu seasons

New Symptoms, Disability Linger One Month After COVID-19 Discharge

Longer hospital stays tied to greater odds of one-month cardiopulmonary symptoms and new disability

Higher Sodium Intake May Be Tied to Worse Migraine Outcomes

Findings for longer duration of migraine headaches and higher Migraine Headache Index Score

School-Based Vision Program Has Positive Impact on Reading

Positive impact on reading seen for female students, those in special education, those in lowest quartile at baseline

High-Quality Diet Tied to Lower Migraine Frequency, Severity

Adherence to either DASH or Mediterranean dietary patterns tied to better migraine outcomes

U.S. Youth Gained Significant Weight During the Pandemic

Largest gains in median body mass index and overweight/obesity occurred in youth aged 5 to 11 years

Migraine Admission Differentially Affected by Race, Income

Patients admitted to hospital with migraine who identified as White had higher income; race did not impact length of stay in hospital

Judge Rules Against Florida Ban on School Mask Mandates

The question of who can decide mask mandates has been debated since July

Biden to Strengthen Push for Vaccine Mandates in New COVID-19 Plan

The new plan involves six steps, according to White House press secretary

18- to 24-Year-Olds at Highest Risk for Weight Gain

Compared with those aged 65 to 74 years, adults aged 18 to 24 years had highest odds for transitioning to overweight, obesity

Very High Antibiotic Use May Up Risk for Proximal Colon Cancer

Inverse association seen for antibiotic use and rectal cancer, which seems to be driven by women

Compensation Strategies Benefit Parkinson Patients With Gait Impairment

Patient-rated efficacy for compensation strategies is high; varies based on the context in which strategies are applied

Risk for Sudden Cardiac Death Up for People Living With HIV

Risk for sudden cardiac death increased among people living with HIV with elevated HIV viral load or low CD4 cell counts

Women, Minority Groups Still Lagging in Clinical Faculty Positions

Racial and ethnic diversity grew more slowly than representation of women in U.S. academic medicine from 1990 through 2019

Chronic Kidney Disease May Be Overestimated in the Elderly

Using a fixed estimated glomerular filtration rate threshold rather than an age-adapted definition may overestimate the burden of CKD

A Number of Men May Stop Active Surveillance for Prostate Cancer

Transition to definitive treatment more likely for patients with additional accompanying medical conditions

Health Care Disproportionately Spent on White Americans

White Americans benefit from greater than average spending on preventive care versus non-White populations

Exercise Habit Prior to Breast Cancer Chemo May Aid Cognition

Adherence to physical activity guidelines throughout chemotherapy was associated with better self-reported cognition

More Than One in 10 Elderly Adults Experience Mistreatment

Race appears to be an important social determinant

Outcomes for Acute Stroke Better With Mobile Stroke Units

Utility-weighted disability outcomes at 90 days better with mobile stroke units versus standard management with emergency medical services

mRNA COVID-19 Vaccines Immunogenic in Immunosuppressed Patients

Titers of anti-S IgG lower for patients with chronic inflammatory disease receiving glucocorticoids or B-cell depletion therapy

Family Availability Impacts Formal, Informal Dementia Care

Receipt of informal care up, while formal care use is lower for those with dementia and disability with greater family availability

Number of Homebound Older Adults Up in 2020

Biggest increases seen among Black, Hispanic individuals, although they were less likely to be living alone

U.S. COVID-19 Cases Now Top 40 Million

COVID-19 has roared back during a summer that began with Americans hopeful that the worst was behind them

Baricitinib Does Not Cut COVID-19 Progression in Hospitalized Adults

But placebo-controlled trial shows lower all-cause mortality at 28 days and 60 days in patients receiving baricitinib plus standard of care

Patient-Reported Outcome Measures May Aid Psoriasis Treatment

Including patient-reported outcome measures in routine care may facilitate individualized treatment for psoriasis

Office Environment May Trigger Asthma in Some Workers

Given the relative safety of office environments, occupational-related asthma causes may be overlooked, authors say

AAP Updates Recommendations for Influenza Vaccination in Children

Influenza vaccination recommended for all children age 6 months and up; no product preferred over another

Consensus Statement Defines Remission of Type 2 Diabetes

Remission defined as HbA1c <6.5 percent for at least three months after cessation of glucose-lowering pharmacotherapy

Psoriasis Not Linked to Preclinical Markers of Dementia

After adjustment for confounders, psoriasis may be linked to lower risk for developing dementia

New COVID-19 Cases, ED Visits Up for Children Since July 2021

Second study shows increase in COVID-19-associated hospitalization rates since delta strain became predominant in U.S.

Sleep Disorders Highly Prevalent in Children With Migraine

Higher Children's Sleep Habits Questionnaire total score correlated with higher frequency of severe attacks, lower drug efficacy

Rapid Intervention Can Contain Multidrug-Resistant Candida Auris

Enhanced laboratory surveillance identified Candida auris in postacute care facilities in Orange County, California in 2019

Genetic Risk Not Better for Predicting Schizophrenia Outcomes

Polygenic risk scores did not improve performance of predictive models relative to clinical features obtained from standard psychiatric interview

Perioperative Acetaminophen Ups Pain Outcomes After Shoulder Surgery

Findings show decreased opioid consumption, better overall pain control following primary rotator cuff repair

Post-Acute Kidney Sequelae Studied in COVID-19 Survivors

Graded increase seen in risks for kidney outcomes according to the severity of the acute infection

Which Cancer Patients Need a COVID-19 Booster Shot Most?

NCCN guidance says several groups should be considered eligible immediately for a third dose of either of the mRNA vaccines

Interim Data Show No Increase in Serious Outcomes Post-COVID-19 Vaccination

Incidence of ischemic stroke, appendicitis, or acute myocardial infarction not increased one to 21 days after mRNA COVID-19 vaccination

New COVID-19 Cases 300 Percent Higher This Labor Day Weekend Than Last Year

The surge in new cases could really hit a high point in about two weeks from now

Recent Cannabis Use Linked to History of MI for Younger Adults

History of myocardial infarction associated with cannabis use more than four times/month and with smoking as primary method of consumption

Journal Editors Call for Action to Curb Rising Global Temperatures

Risks to health and the environment include heat-related morbidity and decline in global yield potential for crops

Cisplatin-Induced Hearing Loss Up for Young Children With Cancer

Cumulative incidence highest in patients aged 5 years and younger; factors that influence development include cumulative dose of cisplatin

New ‘Mu’ Coronavirus Variant Being Watched Closely: Fauci

Variant has not taken extensive hold in the United States at this point, but NIAID is taking it 'very seriously'

Americans’ COVID-19 Medical Bills Are Set to Rise

Research shows that the average COVID-19 hospitalization costs about $40,000

Pfizer to Ship Smaller Packages of COVID-19 Vaccine to Cut Waste, Boost Uptake

CDC says smaller packages of the vaccine may be available by October

COVID-19 Cases Rise Sharply Among Children as School Year Starts

While cases declined in early summer, they have 'increased exponentially' recently, with more than a fivefold increase in the past month

Teen Vaccine Coverage Mainly Remained Stable in 2020

Coverage with Tdap and MenACWY remained stable from 2019; HPV vaccination increased from 2019

NAMS Updates Position Statement on Osteoporosis Management

Risk factor assessment can identify candidates for screening; nonpharmacologic measures appropriate for all postmenopausal women

Effect of Metabolic Syndrome on WTC-Lung Disease Risk Examined

Reduction of metabolic syndrome factors may reduce the likelihood of WTC-related lung injury in susceptible populations

Organ Transplant Activity Declined During 2020

The most affected organ transplants were kidney, followed by lung, liver, and heart

Policy to Cut Sugar in Packaged Foods, Drinks Could Improve Health

Achieving NSSRI sugar reduction targets could prevent 2.48 million CV events, 0.49 million CV deaths, 0.75 million cases of diabetes in the U.S.

Hopelessness Up for Rural Patients With Ischemic Heart Disease

Nonmarried individuals with ischemic heart disease have higher prevalence of state hopelessness than married individuals

2012 to 2018 Saw Increase in Opioid-Linked Cardiac Arrest

Hospitalizations for cardiac arrest with opioid use linked to higher prevalence of alcohol, depression, and smoking

Active Smoking, HTN or Diabetes, Family History Predict Early MI

In multivariable analysis, strong predictors for MI ≤45 years were hypertension or diabetes, active smoking, family history, BMI ≥30 kg/m2

Current Guidelines May Lead to Antibiotic Overuse for SARS-CoV-2 Pneumonia

Bacterial superinfection at time of intubation occurred in <25 percent of patients; reduced antibiotic use seen with bronchoalveolar lavage-based management versus current guidelines

Myocarditis After COVID-19 Vaccination May Resolve Quickly for Youth

However, the long-term effects of myocarditis in children associated with COVID-19 vaccination are unknown

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Home Hazard Removal Program Cuts Rate of Falls Among Elderly

While the program did not reduce the hazard of falls, authors say it nonetheless may be an important, cost-effective intervention

Another HIV Vaccine Trial Canceled Due to Poor Results

Cancellation is the latest in a string of failures for HIV vaccine research

Depression, MS May Have Synergistic Effect on Mortality Risk

People with multiple sclerosis, with or without depression, have increased risks for incident vascular disease, all-cause mortality

AAOS: Some Seniors May Continue Opioid Use After Hip Fracture Surgery

Risk factors for persistent opioid use include prior substance abuse, smoking, higher body mass index, fracture fixation surgery

AAOS: Sports-Related Concussions Up in High School Girls

Soccer, basketball, cheerleading, softball, and volleyball were the activities most frequently associated with concussions

FDA Advisory Panel Set to Meet on COVID-19 Booster Shots

Public session could add clarity or controversy to what some feel has been a confusing decision-making process

Stop Use of Ivermectin for COVID-19: AMA, Pharmacist Groups

No form of ivermectin has been approved to treat or prevent COVID-19

15 Million COVID-19 Vaccine Doses Wasted in U.S. Since March 1

Reasons why doses may be marked as wasted include a cracked vial, an error diluting the vaccine, a freezer malfunction

OxyContin Maker Purdue Pharma Is Dissolved

Sackler family to pay $4.5 billion in bankruptcy settlement, denies any personal responsibility

Drones Can Deliver Defibrillators in Real-Life Emergencies

When drones arrived prior to ambulances for suspected out-of-hospital cardiac arrest cases, the median time benefit was 01:52 minutes

COVID-19 Infection Linked to Increased Risk for Myocarditis

Risk for myocarditis up 15.7-fold for patients with COVID-19 during March 2020 to January 2021 versus those without COVID-19

Odds of COVID-19 Hospitalization Lower After Vaccination

Compared with infected unvaccinated individuals, infected vaccinated individuals report almost all symptoms less frequently

Teachers Not at Increased Risk for Hospital Admission for COVID-19

Risk for hospital admission, severe COVID-19 not increased when schools in Scotland opened in autumn 2020 and in summer 2021

9.7 Percent of All U.S. Persons Uninsured in 2020

Slight decrease seen from 2019, but difference was not significant; 13.9 percent of adults and 5.1 percent of children uninsured in 2020

Mycophenolate Mofetil Treats Immune Thrombocytopenia

Fewer treatment failures and greater response, but poorer quality of life seen when added to a glucocorticoid for first-line treatment

Asthma, COPD Tied to Worse COVID-19 Outcomes

Individuals should continue to receive asthma care and take asthma medications during the pandemic

U.S. COVID-19 Vaccination Rates Climb in August

Only 20 percent of American adults now say they will not get immunized, the lowest number ever

Most Highly Allergic People Can Be Safely Immunized Against COVID-19

Algorithm enables immunization of most individuals, with 0.7 percent developing anaphylactic reaction after one BNT162b2 dose

Two Top Officials in FDA Vaccine Review Office to Retire

Retirements come as agency mulls decisions about COVID-19 vaccine approvals, authorizations for younger children, and booster shots.

Screening Seniors for A-Fib Reduces Risk for Adverse Outcomes

Reduction seen in combined end point of stroke, systemic embolism, bleeding leading to hospitalization, death

CDC: Unvaccinated Should Not Travel This Labor Day Weekend

Agency urges fully vaccinated people to travel with precautions, take infection risk into consideration

Individuals With COVID-19 Most Infectious Around Symptom Onset

Individuals are most infectious in the two days before and three days after symptom onset

Severe Eczema Tied to Depression, Internalizing Behaviors in Children

Mild-to-moderate atopic dermatitis not linked to symptoms of depression, but linked to internalizing behaviors from age 4 years

Periodontitis May Raise Risk for New Cardiovascular Events

Presence of periodontitis at baseline linked to increased odds for new cardiovascular events

Guidance Issued for Preventing Cutaneous SCC in Solid Organ Recipients

For five of six actinic damage and skin cancer index stages, consensus-based recommendations developed

Low-Field Portable MRI Detects Intracerebral Hemorrhage

Authors say low-field portable magnetic resonance imaging may be useful in resource-limited settings

Predictors of Upper GI Bleeding Identified After Acute MI

UGIB after MI linked to increased risk for all-cause mortality and stroke, but not recurrent myocardial infarction; predictors of UGIB include age and smoking status

Antihypertensives Linked to Reduced Mortality in Colorectal Cancer

Reductions in mortality seen in association with ACE inhibitors, beta-blockers, thiazide diuretics

Removing Race Term From CKD-EPI Could Worsen Cancer Care for Blacks

Removing race from CKD-EPI will calculate lower eGFR for Black patients and exclude more from receiving chemo

Maternal Mortality in the U.S. Higher Among Black Women

Postpartum cardiomyopathy, preeclampsia, and eclampsia are leading causes of maternal death for Black women

Risk for Asthma at Age 4 Years Higher After Pneumonia in Infancy

Risk slightly higher after introduction of nationwide pneumococcal conjugate vaccine

Burden of Hospital-Acquired SARS-CoV-2 Infection Estimated

Authors say that approximately one-tenth of patients with COVID-19 in U.K. hospitals were infected after admission

2008 to 2017 Saw Drop in Malignant Brain Tumor Incidence

Incidence among children, adolescents increased 0.5 to 0.7 percent; malignant tumor incidence highest for males, non-Hispanic Whites

Vaccines’ Power Against COVID-19 Hospitalization Fades in Elderly

Hospitalization rates among fully vaccinated higher among older residents of nursing homes and among those with underlying conditions

Toxic Leaded Gasoline Is Finished Globally

Use of the fuel has been linked to a wide range of human health problems

Risk for Hospitalization, ED Use Up With SARS-CoV-2 Delta Variant

Risk increased for being admitted to the hospital or attending emergency care within 14 days with delta variant

Monoclonal Antibody Therapy May Cut COVID-19 Hospitalizations

Lower hospitalization rates seen at 14, 21, 28 days for high-risk patients with mild-to-moderate COVID-19 who received casirivimab-imdevimab

2019 to 2020 Saw Increase in Benzodiazepine Overdose ED Visits

Benzodiazepine deaths increased from April-June 2019 to April-June 2020, with larger increase for illicit benzodiazepine deaths

Substance Use Disorder Prevalent for Young Adults With ADHD

Odds increased for developing alcohol use disorders, cannabis use disorders, other drug use disorders

Fixed-Dose Combination Therapies Reduce Cardiovascular Risk

Fixed-dose combo with BP-lowering meds, statin, and aspirin yields largest reduction in cardiovascular risk

Outcome Good at One Year for Majority of PIMS-TS Patients

Patients presenting with impaired cardiac function without aneurysm on echocardiography had all recovered by day 74

CDC Recommendations for Influenza Vaccination Updated for 2021-2022

ACIP makes no preferential recommendation when more than one licensed, recommended vaccine is available

AAOS: Knee Replacement Readmissions Higher Among Marijuana Users

Readmission rates higher for preoperative marijuana users compared with nonusers at 90 days and at one year following total knee arthroplasty

Individual A-Fib Episodes Tied to Recent Alcohol Intake

AF episodes also linked to higher odds of peak blood alcohol concentration, total area under curve of alcohol exposure

Bystander Rescue Breathing CPR Beneficial for Pediatric OHCA

Odds of neurologically favorable survival improved for RB-CPR versus compression-only CPR

Stockholm3 Test May Aid Risk Prediction in Prostate Cancer Screening

Stockholm3 of 0.11 or higher combined with MRI-targeted and systematic biopsies could detect significant cancers, reduce overdetection

42.4 Percent of U.S. Teens Have Received at Least One COVID-19 Shot

Vaccination coverages vary by state, with rates of one dose or more ranging from from 20.2 percent in Mississippi to 70.1 percent in Vermont

Vitamin D Supplementation No Aid to Muscle Health

Review finds no beneficial effects on muscle function, strength, or mass

Prescriptions Rise for Veterinary Drug for COVID-19 Patients

Increase in demand for ivermectin has been accompanied by a fivefold increase in calls to poison control centers

Pain Management Skills Class Aids Those With Chronic Low Back Pain

Findings show noninferior outcomes at three months versus cognitive behavioral therapy

High Demand for At-Home COVID-19 Tests Could Hamper Supply, Abbott Says

Sales have skyrocketed due to the surge in cases driven by the highly transmissible delta variant

Working Night Shift May Up Risk for Atrial Fibrillation

Risk increased for both current and long-term exposure to night shift work regardless of genetic risk for atrial fibrillation

Daily Average of COVID-19 Hospitalizations in U.S. Hits 100,000

COVID-19 deaths have also risen to an average of more than 1,000 a day for the first time since March

Neurocognitive Effects of Ketamine for Depression Examined

Findings based on a systematic literature review of studies reporting the use of ketamine, esketamine for treatment-resistant depression

U.S. to Be Removed From European Union Safe Travel List

Change not mandatory; EU member nations can decide for themselves whether or not to impose the new measures

Higher Vitamin D Intake Linked to Reduced Risk of Early-Onset CRC

Inverse association significant and stronger for dietary sources of vitamin D versus supplemental vitamin D

COVID-19 Vaccine Hesitancy Up for Racial, Ethnic Minority HCWs

Vaccine hesitancy highest among Black and Hispanic or Latino health care workers; concerns include side effects, newness of vaccine

Walnut Intake Linked to Modest Decrease in LDL Cholesterol in Seniors

Significant decreases in total cholesterol, LDL-C, intermediate density lipoprotein cholesterol, with no increase in weight

Ultra-Low-Dose Combo Cuts Systolic BP in Hypertension

Reduction in systolic blood pressure greater at week 12 with fixed-dose quadruple quarter-dose combo versus standard-dose monotherapy

Good Recovery at One Year for Most COVID-19 Hospital Survivors

However, survivors had more problems with mobility, pain or discomfort, anxiety or depression at one year than controls

Obesity Ups Medical Spending for Long-Term Cancer Survivors

Survivors with obesity have additional $3,216 in medical spending per person per year, translating to $19.7 billion in 2016

Model Predicts Risk for Patients on Waitlist for Cardiac Surgery

Clinical risk model predicts risk for composite outcome of death and unplanned cardiac hospitalization for patients on cardiac surgery waitlist

Cognitive Remediation Benefits Patients With Schizophrenia

Benefits include cognitive and functional outcomes even for severely affected patients

Ultrasound Detects Ulcerative Colitis Disease Activity

New index shows strong correlation with endoscopically determined disease activity

Breast Cancer Screening Down Among Low-Income Women During Pandemic

Eight percent drop in screenings at 32 community health centers means about 47,517 fewer mammograms, 242 missed breast cancer diagnoses

Awake Prone Positioning May Prevent Intubation in COVID-19

Significant reduction seen in intubation with prone positioning for hospitalized patients with acute hypoxic respiratory failure

Patterns of Nicotine Product Use Examined for U.S. Teens

Estimates of health risks linked to nicotine product use among adolescents depend on risk assigned to vaping versus combustible products

History of Concussion Impacts Cingulate Cerebral Blood Flow

Greater declines seen in midcingulate cerebral blood flow at subacute phase and in posterior cingulate CBF at one year after return to play

Fear of Recurrence Persists for Some Prostate Cancer Survivors

Predictors include lower level of education, years since radical prostatectomy, FCR, no current adjuvant therapy, anxiety

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Furniture, TV Tip-Over Injuries Send Many Young Children to ED

Authors urge a mandatory safety standard for manufacturers and for families to anchor furniture to avoid head/neck injuries

FDA Tells Three Small E-Cigarette Makers to Stop Selling Flavored Products

Agency says companies have not provided 'sufficient evidence' that any possible public health benefits of e-cigarettes outweigh the risks

Fratelli Beretta Antipasto Trays Are the Source of Salmonella Outbreak: CDC

Agency says investigation is continuing to try to determine if additional products are linked to the outbreak

FDA Approves First Nerve-Stimulation Device to Aid Stroke Recovery

Vivistim System is a prescription therapy for ischemic stroke patients who have moderate-to-severe difficulty moving their arms and hands

Half of American Workers Support COVID-19 Vaccination, Mask Mandates in Workplace

Poll was conducted before the FDA granted full approval to the Pfizer COVID-19 vaccine

Adverse Events Associated With BNT162b2 Vaccination ID’d

Vaccination not associated with elevated risk for most of the adverse events examined; association found with increased risk for myocarditis, but risk higher in association with SARS-CoV-2 infection

Adults With Disabilities Have Worse Mental Health During COVID-19

Adults with disabilities more often report that the pandemic makes it harder for them to access care, medication

Risk Factors ID’d for Lower-Limb Amputation for PAD in Urban Areas

In metropolitan areas, lower median household income and higher Distressed Communities Index score tied to increased amputation rate

Current, Recent SARS-CoV-2 Infection May Up VTE Risk After Surgery

Substudy of prospective cohort study shows link between SARS-CoV-2 infection and increased risk for postoperative venous thromboembolism

Magnets in Consumer Electronics Can Interfere With Medical Devices

In close proximity (1 to 11 mm), static magnetic fields created by iPhone 12, Apple Watch 6 models can interfere with pacemakers, ICDs

Dementia Risk Score Linked to MRI Markers of Brain Atrophy

Higher scores on Lifestyle for Brain Health index linked to higher volumes of white matter hyperintensities, lower scores for cognitive function

Most Children Experience Fluctuations in ADHD Symptoms

While nearly one in three will experience points of remission of ADHD symptoms, most experience recurrence over time and few outgrow it

Vitamin D Does Not Impact Kidney Outcomes in Prediabetes

Secondary analysis of randomized trial shows no difference in progression of KDIGO risk scores with daily vitamin D versus placebo

Home Hospital Model Creates Capacity, Delivers Quality Care

Findings show model can successfully free up hospital beds by treating some patients at home during a pandemic

Reading Clinic Visit Notes Benefits Older Adults

Older adults with chronic conditions report reading notes helped them to remember their care plan, medications

Learning Environment Issues Tied to Medical School Burnout

Those reporting mistreatment may also experience exhaustion, disengagement, and career regret

Moderna Readies for Full Vaccine Approval, as Pfizer Submits Data on Booster Shot

Right now, Moderna vaccine only authorized for emergency use in Americans 18+ years; Pfizer boosters available to immunocompromised

Record High COVID-19 Cases and Deaths Reported in Florida

As of Tuesday, Florida had reported a record average of 227 COVID-19 deaths a day this week

WHO Team Says Search for Coronavirus Origins at Standstill

Agency published an analysis in March that concluded the virus likely jumped to humans from animals

SARS-CoV-2 Shot Continues to Prevent Infection, Hospitalization With Delta Variant

SARS-CoV-2 infection rate and hospitalization rate 4.9 and 29.2 times higher for unvaccinated versus fully vaccinated persons

Breast Density Linked to Risk for Invasive Breast Cancer in ≥65s

Risk for invasive breast cancer increased with increasing breast density for women aged 65 to 74 years, 75 years or older

Some High-Priority Groups More Likely to Stop Taking PrEP

Younger individuals, African American and Latinx, those with substance use disorders more likely to discontinue PrEP

State Limits on Initial Opioid Rx Duration May Influence Prescribing

Decreases in days of opioid prescribed for initial prescriptions in Medicare beneficiaries especially pronounced among surgeons, dentists

Outcome Measure Developed for Crohn’s Perianal Fistula

Crohn's Anal Fistula QoL has good internal consistency, excellent stability, good responsiveness and construct validity

1990 to 2019 Saw Doubling of Number of People With Hypertension

Treatment and control rates vary, with largest improvements in high-income countries, some upper-middle-income countries

SARS-CoV-2 Vaccine Effectiveness 66 Percent During Delta Predominance

Vaccine effectiveness for all three vaccines decreased from 91 percent in months preceding delta predominance

Suicide Ideation Rates Reduced Among Veterans During COVID-19

Risk factors for new-onset suicide ideation include low social support, lifetime PTSD and/or depression, worsening of social relationships

Rates of Obesity, Weight Gain Up for Transmasculine Individuals

Prevalence of obesity and weight gain higher after hormone therapy for transmasculine versus transfeminine individuals

Nephrology Referrals ID Many Patients at Low Risk for Progression

Potential referral volume could be reduced if referral was restricted to patients with predicted risk ≥1 percent in addition to laboratory criteria

One in Four Older Adults Not Asked About Alcohol Use

Authors say physicians should screen and counsel older adults on alcohol use

Psoriatic Arthritis Worsens QoL in Patients With Psoriasis

Individuals with psoriasis/PsA have decreased ability to participate in social roles and activities, more depression symptoms

J&J Says Booster Shot Ups Immune Response to COVID-19

The Johnson & Johnson vaccine was not part of the government's initial booster plan, announced last week

Risk for Bell Palsy Up 42 Days After First Dose of CoronaVac

Hong Kong study shows small increased risk after Sinovac Biotech vaccine, but no significantly increased risk after BNT162b2 vaccine

Pentagon Says Troops Must Start Lining Up Now for COVID-19 Shots

The Pfizer vaccine will be added to the list of required shots for U.S. troops

Survival Rates Lower for Black Liver Transplant Recipients

For Blacks versus Whites, differences in post-LT mortality narrowed between 2002 and 2009, increased between 2014 and 2018

SARS-CoV-2 Antibodies ID’d in Breast Milk of Vaccinated Lactating Women

After the second dose of mRNA COVID-19 vaccine, breast milk levels of IgG(S1) increased and correlated with corresponding serum levels

Liraglutide Reduces Visceral Fat in Overweight, Obese Adults

Liraglutide plus diet and physical activity counseling reduce visceral and ectopic fat in overweight, obese adults at high risk for CVD

Maternal Obesity May Up CRC Risk in Adult Offspring

Authors say this association may be contributing to increasing incidence rates of colorectal cancer in younger adults

Mishaps Common During Patient Transport From Emergency Care

Common risk events during intrahospital patient transport from ED included limb trapping/displacement, collisions, IV line or catheter issues

Donor HLA Evolutionary Divergence May Predict Liver Transplant Rejection

Class I HED of the donor is associated with higher risk for acute and chronic rejection of the liver transplant

2001 to 2017 Saw Increase in Prevalence of T1DM, T2DM in Youth

Relative increase of 45.1 percent reported in prevalence of type 1 diabetes and relative increase of 95.3 percent reported in type 2 diabetes

No Benefit Found for COVID-19 Convalescent Plasma in High-Risk Outpatients

Disease progression was not reduced with convalescent plasma for outpatients aged 50 years or older with one or more risk factors

More Than 10 Percent of Adults Missed Health Care in Spring 2021

In addition, 9.2 percent of parents report delaying or forgoing care for their children for fear of exposure to the coronavirus

Cycling Common Cause of Sports-Linked Traumatic Spinal Injury

Within sports-related TSIs, rate of spinal cord injury was 13 percent for cycling injuries versus 41 percent for contact sports

Alcohol Use Down, Nicotine Use Up for Teens During COVID-19 Pandemic

Likelihood of using substances up when youth were stressed by pandemic-related uncertainty, family experienced material hardship

Morbidity Risk Up Among Black and Hispanic Term Newborns

More Black and Hispanic women deliver in hospitals ranking in the highest-morbidity tertile compared with White, Asian American women

FDA Warns Against ‘Off-Label’ Use of Pfizer COVID-19 Vaccine in Younger Children

Adult vaccine dose is much higher than doses being tested in younger children

Pain, Fatigue, Depression, Anxiety Prevalent After MS Diagnosis

Most patients had co-occurring symptoms: 21.3, 19.1, and 17.4 percent had two, three, and four symptoms, respectively

Salmonella Illness in 17 States Tied to Salami, Prosciutto

Twelve people have been hospitalized; no deaths have been reported

Poverty Tied to Worse Functional Status in Rheumatoid Arthritis

Patients with lower socioeconomic status also have increased probability of functional decline in longitudinal analyses

Factors Linked to Development of Pediatric Psoriasis Identified

Factors independently linked to development include atopic dermatitis, family history of psoriasis, skin and fungal infections

USPSTF Says Start Diabetes Screen at Age 35 for Those With Overweight, Obesity

Overweight or obese adults should be screened for prediabetes, type 2 diabetes and offered or referred for preventive interventions

Teens, Young Men Have Higher SARS-CoV-2 Infection Rates

Standardized infection ratios were lowest in children and in adults aged 70 years or older compared with overall population

Risk for Death Increased for Infants After Maltreatment Report

Increased risk for death attributable to medical causes for infants reported for alleged maltreatment

More Frequent Alcohol Consumption Ups Risk for GI Cancers

Amount of alcohol consumed in each occasion seems to be a less important risk factor

COVID-19 Mortality Lower for Vaccinated Solid Organ Transplant Recipients

Second study shows increased risk for breakthrough COVID-19 infection and associated mortality for SOTRs versus general population

Roxadustat Treats Anemia in Non-Dialysis-Dependent CKD

Pooled data show roxadustat versus placebo increases hemoglobin levels with an acceptable profile for cardiovascular safety

Guidance Issued for Colonic Volvulus, Acute Colonic Pseudo-Obstruction

Clinical practice guideline addresses diagnosis and management of colonic volvulus, acute colonic pseudo-obstruction

Pfizer-BioNTech COVID-19 Vaccine Receives Full FDA Approval

Prescribing information includes warning about risks for myocarditis and pericarditis, particularly in men younger than 40 years

Drinking and Smoking After First Trimester May Up Late Stillbirth

No significantly increased risk observed for pregnancies prenatally exposed to drinking only or smoking only

Higher Flavonoid Intake May Lower Systolic Blood Pressure

Higher consumption of berries, red wine linked to lower SBP; association partly explained by microbial factors

No Permanent Lung Damage Observed After COVID-19 Recovery

No difference seen between lung parenchyma of COVID-19 survivors and controls in specimens from unrelated elective lung resections

Most Parents Plan to Send Children to In-Person Learning, Despite COVID-19

Survey revealed racial gap between parents' preferences and safety concerns

Among Persons With HIV, More Finish Short-Course TB Prophylaxis

Treatment completion 90.4 percent for three months of rifapentine-isoniazid versus 50.5 percent for six months of isoniazid

Israeli Study Shows Pfizer Booster Gives Seniors Big Rise in Immunity

Israel approved booster shots for people aged 60 years and older late last month; the government lowered the age of eligibility to 40 years last week

Pentagon to Make COVID-19 Vaccination Mandatory for Military

Officials are preparing to issue guidance to require vaccination, although no exact timeline has been given

Stop Using Ivermectin Veterinary Drug to Treat COVID-19, FDA Urges

No form of ivermectin has been approved to treat or prevent COVID-19, the agency emphasized