Physician’s Briefing Weekly Coronavirus Roundup
Poll: Most Older Adults Want to Age in Place
Authors urge investing in home improvements to ensure future independence
Three Main Barriers Hamper Weight Loss Surgery for Obese Teens
Barriers include lack of information, social stigma, and access issues related to costs
Inflammatory Skin Diseases Classified at Molecular Level
Molecular signatures for inflammatory skin diseases can help with classification of clinically indeterminate skin rashes
New Law Allows FDA to Police E-Cigarettes Made With Synthetic Nicotine
Vaping companies must now follow the same federal sales restrictions and age requirements as tobacco product companies
Incidence of Herpes Zoster Up for ≥50s With COVID-19 Diagnosis
Increased herpes zoster risk found for those with versus without COVID-19, with more pronounced risk following COVID-19 hospitalization
Posttraumatic Epilepsy More Likely to Be Drug Resistant
Lowest quality of life reported for those with posttraumatic epilepsy, drug-resistant epilepsy
Fourth Dose of BNT162b2 Offers Protection Against Severe COVID-19
Protection against COVID-19 did not wane in six weeks after receipt of fourth dose; protection against infection waned
COVID-19 Linked to Increased Risk for DVT, PE, Bleeding
Rate ratios were highest for critical COVID-19, and during first versus second and third pandemic waves in Sweden
Intra-Articular Injection of Triamcinolone Beneficial in Hip Osteoarthritis
Pain improved with ultrasound-guided intra-articular hip injection of corticosteroid and local anesthetic added to best current treatment
ACC: Lasting Reduction in BP Seen With Radiofrequency Renal Denervation
Significant reductions in systolic and diastolic BP observed at up to 36 months following intervention versus sham control procedure
Benefits of Smoking Cessation Quantified in Patients With ASCVD
About five event-free years gained through either quitting smoking or the use of three medications combined in persistent smokers
Insomnia Linked to Recurrent MACE in Coronary Heart Disease
Association remained significant after adjustment for major coronary risk factors, comorbidity, anxiety and depression symptoms
Recommendations Updated for Management of Heart Failure
Sodium-glucose cotransporter-2 inhibitors recommended for HF with reduced, mildly reduced ejection fraction
Hundreds of Overseas Flights Canceled After Mask Rules Dropped
Recent increase in canceled flights is the result of 'higher than usual staff sickness levels' due to recent surge in COVID-19
Report Says Nursing Home Industry Needs an Overhaul
Staffing was a major focal point of the study, which advocates say is too low in sheer numbers, while staff is also untrained and underpaid
Despite Improvements, Disparities in Faculty Diversity Persist
Compared with U.S. demographic characteristics, female representation increased among clinical faculty, but URM representation decreased
Middle Ear Effusion Up for Children With Tracheostomy on Ventilator
Mechanical ventilation increases risk for development of middle ear effusion in tracheostomy-dependent children
ACC: Low-Sodium Intervention Has Little Benefit in Heart Failure
Low-sodium diet did not reduce composite primary outcome of cardiovascular admission to hospital or ED or all-cause death
Sitting Tai Chi Program Benefits Subacute Stroke Survivors
Tailored sitting tai chi program in the subacute phase can improve recovery outcomes in stroke survivors
Tebipenem Pivoxil Hydrobromide Noninferior to Ertapenem for UTI
Findings observed in patients with complicated urinary tract infection or acute pyelonephritis
Fear of Cancer Recurrence Prevalent in Patients, Survivors
FCR decreased with age, but was observed across cancer types and continents, and for all time periods since cancer diagnosis
ACC: Bleeding Risk Lower With Tranexamic Acid in Noncardiac Surgery
But, though difference is small, tranexamic acid not noninferior to placebo for primary safety outcome of composite cardiovascular outcome
Substance Use Treatment Cuts Depression With Co-Occurrence
One-third of teens show early depression response with substance use treatment alone
Eligibility Criteria Add to Race Gap in Pancreatic Cancer Clinical Trials
Black patients disproportionately excluded from participation in pancreatic cancer clinical trials
Psychological Interventions + Physical Therapy Ease Chronic Low Back Pain
Pain education, behavioral therapy delivered with physical therapy can help with physical function and pain intensity
Frequent Insomnia Symptoms Can Cause Higher HbA1c
Association seen across multivariable regression, one- and two-sample Mendelian randomization analyses
Serum Sodium in Upper Part of Normal Range Linked to Heart Failure
Serum sodium above 143 mmol/L linked to increased odds of left ventricular hypertrophy, heart failure
FDA Advisers Weigh COVID-19 Booster Shots for Fall
Vaccine experts still guessing at what the ever-changing pandemic will bring
FDA Panel Meets to Craft Future Vaccine Strategy
No official vote is planned, and no specific vaccine products will be discussed
EPA Proposes to Ban Last Form of Asbestos Used in the United States
Asbestos is banned in more than 50 countries and its use in the United States has been declining for years
Biden Makes National Push for ‘Long COVID’ Research
Efforts will include speeding up registrations of 40,000 people both with and without long COVID for a study on the condition
Primary Care-Based Screening Ups Thin Melanoma Detection
Incidence of melanoma thicker than 4 mm did not differ significantly for screened and unscreened patients
Racial Disparities Seen in Adverse Renal Outcomes for Pediatric Lupus
Proportion of admissions with adverse renal outcomes decreased from 2006 to 2019, but racial disparities persisted
Teens With Severe Substance Use Disorder May Not Grow Out of It
Many teens with severe substance use symptoms had symptoms for alcohol, cannabis, prescription, and other drug use disorders in adulthood
Simplified Approaches to Hypertension Screening Seem Reliable
Surveys conducted across 60 countries reveal screening strategies using the second blood pressure reading had the smallest misdiagnosis rate
Fine Particulate Matter Levels Up With Social Cannabis Smoking
PM₂.₅ level increases with smoking in the home, decays gradually after smoking stops, and remains elevated indoors 12 hours later
AAD: Skin Videomicroscopy Biomarker May Help Predict Cancer Relapse
Assessment of leukocytes adherent to and rolling along vessel wall may help predict outcomes after HCT for hematologic cancer
Plastic Surgery Consultations for Complex Cases Add Financial Value to Hospitals
Study shows substantial increase in net revenues for complex surgeries with plastic surgeon consultants
Cardiac Complications Up After SARS-CoV-2 Infection Versus Vaccines
Incidence of cardiac outcomes after mRNA COVID-19 vaccination highest in males aged 12 to 17 years, but risk 1.8 to 5.6 times higher after infection
Selfies Give Distorted Facial View
Selfies introduce measurable distortions in the size and perception of facial features
Inadequate Sleep Tied to Abdominal Fat Accumulation
Fat accumulation seen for subcutaneous and visceral abdominal fat depots
Most COVID-19 Patients Benefit at Long-Term Acute Care Hospitals
Patients treated for COVID-19 discharged with greater improvements in ambulation distance, assistance needs versus reference patients
Vaccination Offers Extra Protection After SARS-CoV-2 Infection
Two studies show additional protection against reinfection and COVID-19-linked hospitalization with vaccination
Burst Wave Lithotripsy Promising for Breaking Up Kidney Stones
Median of 90 percent comminution of total stone volume observed in the first 19 humans undergoing burst wave lithotripsy
ACC: Childhood Risk Factors Linked to Cardiovascular Events in Midlife
Change in combined-risk z score from childhood to adulthood also linked to cardiovascular events in midlife
Migraines May Affect Outcomes in Takotsubo Cardiomyopathy
Odds of mortality and acute complications lower for Takotsubo cardiomyopathy patients with versus without migraine headaches
Study Explores Characteristics of Vestibular Migraine
Severe headache associated with age 43 years or younger, while severe vertigo associated with age 41 years or older
ACC: Treatment Beneficial for Mild Chronic HTN in Pregnancy
Reduction seen in risk for primary outcome event, with no increased risk for small-for-gestational age birth weight
AAOS: Patients Mostly Satisfied After Flatfoot Reconstruction
Postoperatively, physical activities less difficult for 50 percent, equally difficult for 33 percent, and more difficult for 17 percent
U.S. Nursing Home Deaths Reach Lowest Levels Since Pandemic Began
Nursing home residents continue to be more vulnerable both because of their age and underlying medical conditions
A-Fib Detected in Nearly Three in 10 Cryptogenic Stroke Patients
Most patients diagnosed with AF were asymptomatic; arrhythmia detected with 12 months of continuous cardiac monitoring
Risk for Atrial Fibrillation Recurrence Increases With Body Weight
Body mass index linked to both short- and long-term risk for return of the heart rhythm disorder following ablation
CDC Director Walensky Announces Sweeping Review of Agency
Revamp would focus on improving the nation's public health workforce, data modernization, laboratory capacity, rapid response to outbreaks
COVID-19 Vaccination Early in Pregnancy Not Linked to Fetal Anomalies
Vaccination within teratogenic window not linked to presence of congenital anomalies identified on ultrasonography
FDA Warns of U.S. Norovirus Cases Linked to Canadian Oysters
Oysters were distributed in 13 states, but others may also have received them through further distribution within the United States
Sexual, Emotional Abuse in Childhood May Up Multiple Sclerosis Risk
Exposure to two or all three abuse categories associated with further increased risk for multiple sclerosis
Medicare Now Covers COVID-19 Tests Bought at Drug Stores
Now the 59 million Americans covered by Medicare Part B can get up to eight free, at-home tests each month
Clinical, Economic Impact of Nonfatal Firearm Injuries Explored
Increases in substance use disorders, psychiatric disorders, pain diagnoses, health care use and spending seen in survivors
Commercial-to-Medicare Hospital Price Ratios Stable 2012 to 2019
Trends in ratios varied considerably across hospital referral regions
WHO: 99 Percent of Planet’s Population Breathes Dirty Air
Air quality is the worst in WHO Eastern Mediterranean and Southeast Asia regions
Napping More Frequent in Women With Chronic Migraine
Nap duration linked to greater headache severity, lower sleep efficiency in chronic migraine
Body Mass Index, Obesity Up During the Pandemic for U.S. Adults
Higher rates of alcohol consumption and lower smoking rates may have contributed to higher obesity
2014 to 2019 Saw Decrease in Postoperative Opioid Use for Children
Rapid opioid deadoption identified beginning in late 2017; was first seen in teens followed by school- and preschool-aged children
BP Genetic Risk Score Linked to Risk for CV Events in Type 2 Diabetes
Each standard deviation increase in BP polygenic risk score linked to 12 percent increased hazard of adverse CV events
Early Ivermectin Does Not Reduce Hospital Admission in COVID-19
Also no decrease seen in prolonged ED visits for patients with COVID-19 symptoms for up to seven days, at least one risk factor for progression
BNT162b2 Prevents Critical COVID-19 in Children and Adolescents
During omicron-predominant period, effectiveness of two doses against hospitalization 68 percent for children, 40 percent for adolescents
AAOS: Outcomes Good for New ACL Repair Technique in Teens
For teens at high risk for failed ACLR, lateral extra-articular tenodesis with modified Lemaire technique used in conjunction with ACLR
AAOS: Early Outcomes Similar for Cementless, Cemented Fixation TKR
Groups did not differ in hospital length of stay, complications, 90-day readmission, revision surgery at two years
New Instrument Developed for Assessing Patient Knowledge of CKD
KART 2.0 can differentiate patients who have spent less than one versus one or more hours speaking to health professionals, reading about transplantation
Fetal Exposure to Cannabis Linked to Adiposity in Childhood
Exposure linked to higher fat mass, fat-free mass, adiposity, and fasting glucose; no link seen with BMI, BMI z-score
Risk for Death by Homicide Up for Cohabitants of Gun Owners
Of homicides occurring at home, sevenfold increased risk for being fatally shot by spouse, partner seen for cohabitants of gun owners
Risk for Acute MI Not Increased With Two-Dose HepB-CpG Vaccine
Noninferiority study shows no increased risk for acute MI with two-dose HepB-CpG vaccine versus three-dose HepB-alum vaccine
Diabetic Eye Complications More Common in Blacks, Hispanics
Additionally, minorities less likely to receive all recommended diabetes care
HTN, T2DM Contribute to Brain Changes in Puerto Rican Seniors
High prevalence of HTN, T2D seen among Puerto Rican cohort; those with both have deteriorating patterns in major white matter tracts
House Passes Bill To Limit Insulin Costs to $35 a Month
Bill now has to pass the Senate with at least 10 Republican votes
160,000 lb of Skippy Peanut Butter Recalled Due to Metal Fragments
Recall was voluntary, and no consumer complaints have been associated with it
Health, Economic Impact of COVID-19 Set to Lessen in Coming Years
Health care use projected to normalize after decline in 2020; remaining federal supplemental spending expected to decrease through 2024
Alzheimer Disease, Related Dementia Diagnoses Up in Medicare Decedents
Percentage of older U.S. decedents with a diagnosis of Alzheimer disease and related dementias increased significantly from 2004 to 2017
Higher Incidence of SARS-CoV-2 Infection in Under 5s During Omicron
Higher incidence rate of infection compared with delta variant, but significantly lower risk of severe clinical outcomes
Mental Health Among High School Students Explored During COVID-19
Students who felt close to someone at school had lower prevalence of poor mental health, had considered or attempted suicide
Living-Donor Liver Transplant Promising for CRC With Liver Mets
Recurrence-free survival of 62 percent, overall survival of 100 percent at 1.5 years after LDLT in select patients
At-Home Visual Acuity Tests Valid Versus In-Office Testing
Printed, mobile phone app, and website at-home self-administered visual acuity tests valid within one line of in-office Snellen visual acuity
Early Use of COVID-19 Convalescent Plasma Cuts Hospitalization Risk
Administration of convalescent plasma within nine days after symptom onset can reduce risk of COVID-19-linked hospitalization
Eight-Gene Model Can Help Predict Progression to Severe Dengue
Model predicted severe dengue progression with 86.4 percent sensitivity and 79.7 percent specificity
Buprenorphine Prescribing for Medicaid Beneficiaries Down in 2020
Despite increases in units per prescription, the amount of buprenorphine dispensed to Medicaid beneficiaries decreased early in the pandemic
VNS May Cut Hospital Costs for Children With Refractory Epilepsy
Antiseizure medication plus vagus nerve stimulation linked to lower hospital costs over time compared with antiseizure medication alone
Physician’s Briefing Weekly Coronavirus Roundup
Universal HepB Vaccination Recommended for Adults Age 19 to 59
Those aged 60 years or older with risk factors should receive vaccine; those without risk factors should be offered vaccine
FDA Advisory Panel Narrowly Votes Against New ALS Drug
Panelists said they hoped results of a larger study, now underway, would provide more evidence on the drug
Biden to Lift Pandemic Rule Restricting Immigrants at Land Border
Once lifted, migrants entering the country to seek asylum will not be quickly turned back because of public health concerns
CDC Lifts Warning on Cruise Ship Travel
Agency still advises passengers to get up-to-date vaccinations before boarding a cruise ship
New White House Website Speeds Access to Free COVID-19 Care
COVID.gov will bring into one place several types of critical COVID-19 information
New-Onset Cardiovascular Complications Common After Stroke
Odds of five-year all-cause mortality up for stroke patients with ACS, atrial fibrillation/flutter, heart failure, severe ventricular arrhythmias
Seizures of Drugs Containing Illicit Fentanyl Increasing in U.S.
From 2018 to 2021, increases seen in number of fentanyl-containing powder seizures, number of pill seizures
Stage Shift Seen With CT Screening for Lung Cancer in the U.S.
Stage shift toward Stage I NSCLC observed following introduction of low-dose CT screening for lung cancer
Memory Concerns Stable, but Incidence of Cognitive Decline Increased
Women, those older than 80 years, and those living in more deprived areas more likely to have memory concern, cognitive decline recorded in primary care
Amygdala Grows Faster Between 6 and 24 Months in Babies With Autism
Amygdala growth rate between 6 and 12 months linked to greater social deficits at 24 months when the infants were diagnosed
In Utero Antipsychotic Exposure May Not Up Neurodevelopmental Disorder Risk
Commonly prescribed antipsychotic medications taken late in pregnancy seem not to meaningfully increase NDD risk in offspring
SARS-CoV-2 Vaccination Seems Safe After MIS-C
No major adverse events seen among 15 children with MIS-C who were subsequently vaccinated against SARS-CoV-2
GLP-1 RA Use May Up Risk for Gallbladder, Biliary Diseases
GLP-1 RA treatment linked to increased risk, especially in trials for weight loss, and with higher doses and longer duration of use
Mini-Slings Noninferior to Mid-Urethral Slings for Stress UI in Women
Rate of patient-reported success similar for women in mini-sling, mid-urethral sling groups at 15 months, 36 months
ED-Initiated Buprenorphine for OUD Often Not Sustained
Many patients filling buprenorphine prescriptions written by emergency physicians do not subsequently fill prescriptions for the treatment
Rotating Shift Work Tied to Delay in Onset of Natural Menopause
Delay in onset of menopause linked to rotating shift work in current and longest job period
Booster Strategies After Janssen Shot Increased Protection Against Omicron
Vaccination with one Janssen dose plus mRNA booster provides higher protection than two Janssen doses
Use of Medications for Opioid Use Disorder Low
Past-year use lowest for adolescents and adults aged 50 years and older
Racial, Ethnic Disparities ID’d in Pediatric Acute Asthma Care
Spanish-preferring Latine children had higher odds of clinic visits for asthma exacerbation than non-Hispanic Whites
Cancer Survivors Face Transportation Barriers to Accessing Care
Survivors who are younger, poor, uninsured or publicly insured, unmarried, or who have functional limitations have greatest barriers
COVID-19 Vaccination Not Linked to Peripartum Adverse Outcomes
Large population-based cohort of more than 22,000 women shows no increased risks with vaccination during pregnancy
21 States Sue to Overturn CDC Public Transport Mask Mandate
Lawsuit claims mask mandate exceeds the authority of the U.S. Centers for Disease Control and Prevention
Probability of False-Positives Lower With Digital Breast Tomosynthesis
Cumulative probabilities of false-positive results substantially lower for biennial versus annual screening, regardless of modality
Global Burden of Melanoma Considerable, Set to Rise by 2040
If 2020 rates continue, burden estimated to increase by about 50 percent for incidence, 68 percent for deaths by 2040
Avocado Intake Linked to Lower Risk for CVD, Coronary Heart Disease
Replacing animal products such as butter, cheese, eggs, processed meat with avocado linked to lower risk for CVD events
Light Alcohol Intake May Not Protect Against Cardiovascular Disease
Heavy consumption tied to exponential increases of cardiovascular disease risk
Preconception Paternal Metformin Linked to Major Birth Defects
Genital birth defects, all in boys, more common among metformin-exposed offspring
CDC Supports Second COVID-19 Booster for Americans 50 Years and Older
Echoing the FDA, the CDC also supported a second booster for 'certain immune-compromised individuals'
Risk, Burden of Diabetes Up After Acute SARS-CoV-2 Infection
Risks and burdens of postacute outcomes increased in graded manner based on COVID-19 severity
Early Aspirin Cuts In-Hospital Mortality With Moderate COVID-19
Largest benefits seen for patients older than 60 years with no increased risk for hemorrhagic complications
USPSTF: Evidence Lacking for OSA Screening in Asymptomatic Adults
The evidence is insufficient to assess the balance of benefits and harms of screening for obstructive sleep apnea in the general adult population
FDA Approves Second COVID-19 Booster for Americans 50+
Agency also authorized a second booster for Americans 12 and older who are immune-compromised
FDA Reviewers Give Thumbs Down to New ALS Drug
Agency said results were 'not persuasive,' citing missing data, mistakes in enlisting patients, other issues
Out-of-State Residents Can Now Seek Medical Aid in Dying in Oregon
Lawsuit that challenged the residency requirement as unconstitutional was settled Monday
1999 to 2018 Saw Increase in Prevalence of Prediabetes in Teens
Disparities in prevalence of prediabetes remained stable and were pronounced in subgroup analyses of sex and BMI category
2019 to 2020 Saw Risk-Linked Deaths From Heart Disease, Stroke Up
Highest risk-associated increases were seen in non-Hispanic Black people followed by Hispanics, non-Hispanic Asian or Pacific Islanders
Motivational Interviewing Not Better in Weight Loss Programs
Evidence lacking that MI makes meaningful difference to weight loss, well-being when added to behavioral weight management program
Live Attenuated Flu Vaccine Does Not Increase Frequency of Asthma Exacerbations
Frequency of asthma exacerbations not increased with live attenuated versus inactivated flu vaccine in children aged 5 to 17 years with asthma
Risks for Anaphylaxis Compared Among IV Iron Products
Rates of anaphylaxis low for IV iron products, but risk for anaphylaxis increased with iron dextran and ferumoxytol compared with iron sucrose
No Adverse Outcomes Seen With SARS-CoV-2 Vaccination in Pregnancy
No significantly increased risk reported for preterm birth, stillbirth, SGA, low Apgar score, or neonatal care admission
For Men Aged 60 to 64, CVD Deaths Up With Warmer Summer Nights
Risk for CVD deaths increased with warmer summer nights for men aged 60 to 64 years in England and Wales; King County, Washington, USA
Memory Deficits Seen in Individuals With ‘Long COVID’
Deficits increased with severity of ongoing self-reported symptoms; severity of initial illness did not influence later cognitive performance
Prenatal Occupational Disinfectant Use Tied to Child Allergies
Risks for asthma, eczema increased in offspring of pregnant women with work-related disinfectant use
Immune Response to SARS-CoV-2 Infection Persists in Children
Ninety-six percent of those with evidence of nucleocapsid antibodies at baseline still had antibodies more than six months later
Risk for Ischemic Stroke Up With Antidopaminergic Antiemetic Use
Increase in risk greatest for metopimazine and metoclopramide; risk for ischemic stroke may be higher in first days of use
COVID-19 Tied to Higher Risk for Pregnancy Complications
Infection tied to worse outcomes for severe maternal morbidity, preterm birth, and venous thromboembolism
Stakes Are High Ahead of FDA Panel Vote on ALS Drug
AMX0035 is a combination of two established drug ingredients -- sodium phenylbutyrate and taurursodiol
Biden Administration to Offer Second COVID-19 Boosters to Those 50+
While a second booster for older adults will be offered, federal health officials will not go so far as to recommend it
Many Local Health Departments Report Harassment During Pandemic
Public health officials reported experiencing structural and political undermining of their professional duties
2004 to 2017 Saw Increase in Appendiceal Cancer
Increase appears to be driven by a rise in carcinoids
Less Than Half of Primary Care Providers Ask About Teens’ Mental Health
Parents also report that it is difficult to get mental health care for teens
Amino Acid Supplementation Beneficial After Fracture Fixation
Reduction in postoperative complications for adults receiving conditionally essential amino acid supplementation
Intimate Partner Violence Referrals Increased After COVID-19 Emergence
Face-to-face consults decreased, but total number of consults, mainly for emotional abuse, increased
Management of Antithrombotics in GI Bleed, Endoscopy Addressed
Guideline addresses management of anticoagulants, antiplatelets during acute gastrointestinal bleeding and in the elective endoscopy setting
Use of Injectable Local Anesthetics Up for Hip Fracture
Increasing use of injected local anesthetics may represent move away from opioid analgesia for hip fracture patients
AMA Poll: Most Physicians Continuing to Use Telehealth
Most users (93 percent) are conducting live, interactive video visits with patients, while 69 percent are conducting audio-only visits
ACC: Use of Salt Substitute to Prevent Stroke Is Cost-Saving
Salt substitute intervention shown to be cost-saving among individuals with prior stroke or uncontrolled high blood pressure living in rural China
Awake Prone Positioning Does Not Improve Outcomes in COVID-19
Findings seen among non-critically ill patients with moderate hypoxemia, admitted to hospital with COVID-19
Videogaming Rehabilitation Studied in Stroke Patients
Use of self-managed, at-home video game rehabilitation compared to other methods for upper-extremity therapy
AAD: Baricitinib Tops Placebo for Hair Regrowth in Alopecia Areata
In two phase 3 trials, baricitinib superior to placebo in terms of percentage of patients with a SALT score of 20 or less at week 36
ACC: Pericardial Effusion Prevalent in Hospitalized COVID-19 Patients
Prevalence of pericardial effusion in hospitalized COVID-19 patients is about 14 percent, but it rarely is attributable to pericarditis
Pregnant Obese, Overweight Women Have Higher Risk of Perinatal Death
Earlier gestational age at delivery may be implicated in many of these obesity-related perinatal deaths
Physician’s Briefing Weekly Coronavirus Roundup
Neurodevelopmental Disorders for Most Children Born <24 Weeks
75 percent born before 24 weeks of gestation had neurodevelopmental disorders; 88 percent had somatic diagnoses
Overtreatment of T2DM Common Among VA Nursing Home Residents
Minority of those overtreated or potentially overtreated have their medication regimens appropriately deintensified
Model Predicts CRC Risk in Ulcerative Colitis Patients With LGD
Four clinicopathological variables significantly associated with advanced neoplasia risk among those with low-grade dysplasia
One in Three Children With Disabilities Experience Violence
Children with disabilities twice as likely to experience any form of violence (physical, emotional, sexual, neglect) than children without disabilities
Survival Up With Bortezomib in T-Cell Lymphoblastic Lymphoma
No differences in EFS or OS seen with/without bortezomib overall or in patients with T-cell acute lymphoblastic leukemia
FDA Authorizes More E-Cigarette Products
Agency said it has acted on approximately 99 percent of the nearly 6.7 million e-cigarette products submitted for authorization
AI Model May Help Predict Ovarian Cancer Treatment Outcomes
Artificial intelligence model trained to recognize distinct morphologic patterns in high-grade serous ovarian cancer at the time of laparoscopy
Higher Internet Use Tied to Poorer Mental Health in Teens
Teens with higher usage self-report higher level of stress, and feelings of sadness and suicidal ideation
Vicious Cycle Seen Between Daytime Napping, Alzheimer Dementia
Excessive daytime napping over a year predicts worse cognitive performance the following year and vice versa
CDC: Vaccinated More Likely to Die During Omicron Wave If They Got J&J Shot
However, breakthrough infections among J&J vaccine recipients were similar or lower compared to the other vaccines
Medical Marijuana May Not Aid Pain, Anxiety, Depression Symptoms
But many obtaining immediate access to a medical marijuana card developed cannabis use disorder
Psychotropic Meds Tied to Risk for Post-COVID Dementia in Seniors
One-year incidence rate of post-COVID dementia was 12.7 percent in adults ≥65 years hospitalized with COVID-19
Outcomes Better With Open Hysterectomy for Early Cervical Cancer
Poorer disease-free survival seen with minimally invasive versus open radical hysterectomy for early cervical cancer at 4.5 years of follow-up
Artificial Sweeteners Linked to Increased Cancer Risk
Risks seen for aspartame and acesulfame-K; higher risks also seen for breast cancer and obesity-related cancers
Airlines Ask Biden to Drop Mask Mandates, COVID-19 Testing
Federal requirement that people wear masks on public transportation was recently extended until April 18
Improved CRC Outcomes With Recent Colonoscopy in IBD
Those with colonoscopy within one and one to three years less likely to be diagnosed at later stage
Incidence of TB Increased 9.4 Percent in U.S. During 2021
Incidence increased among U.S.-born and non-U.S.-born persons; increase may be due to delayed diagnosis during 2020
Nearly One in Three People With Depression Report Owning a Gun
Authors say there is opportunity to cut suicide risk through focused interventions
Mentalizing Imagery Therapy Aids Family Caregivers
Findings show lower depression, anxiety and better well-being versus support group attendance
Midlife Antibiotic Use Tied to Minor Cognitive Decline Later
Small decreases in cognitive scores seen at seven years for women reporting at least two months of antibiotic use during midlife
Hydrocortisone Does Not Up Survival Without BPD in Preemies
Survival without moderate or severe bronchopulmonary dysplasia in extremely preterm infants similar with hydrocortisone versus placebo
Fourth mRNA COVID-19 Vaccine Immunogenic, Safe
Vaccine efficacy 30 percent for BNT162b2 and 11 percent for mRNA-1273 against any SARS-CoV-2 infection
Risk for Myocarditis Low After Third Dose of BNT162b2 Vaccine
Incidence of myocarditis among young men estimated to be 6.43 and 11.25 per 100,000 vaccines in the week, two weeks after third dose
Timing, Type of Food Intake Linked to Mortality Risks in Diabetes
Among people with diabetes, higher intake of processed meat in the evening linked to increased risk for CVD mortality
Violent Assault Risk Up for People With Tourette Syndrome, Chronic Tic
Compared with the general population, individuals with these conditions also more likely to have criminal convictions
Addition of Icosapent Ethyl Cuts CV Risk in Patients With Prior PCI
Risk for cardiovascular events reduced when icosapent ethyl is added to statins in patients with elevated triglycerides and history of prior PCI
Presenting Symptoms Do Not Predict NSTEMI Outcomes
Presenting symptoms, such as chest pain, dyspnea/fatigue, syncope were not independent predictors of death from any cause at one year
Handheld Device Used to Screen for A-Fib in Primary Care Setting
Single-lead ECG device did not increase new diagnoses of atrial fibrillation for those aged 65 years or older compared with usual care
Older Adults Using Statins Have Reduced Risk of Parkinsonism
Lower risk of parkinsonism partly mediated by reduced odds of brain atherosclerosis
Risk of A-Fib Up With Occupational Exposure for Firefighters
Prevalence of atrial fibrillation increased for firefighters with increasing numbers of fires fought per year
Trastuzumab Deruxtecan Ups PFS in HER2+ Metastatic Breast Cancer
Trastuzumab deruxtecan better than trastuzumab emtansine for patients previously treated with trastuzumab and a taxane
QOL Advantages in Young Adulthood for Those Conceived Through ART
Being ART conceived associated with higher scores on social relationships and environmental WHOQoL-BREF domains
Pandemic Tied to Drop in New Cancer Diagnoses
While weekly detection increased from March 2020 low, incidence rates have not fully recovered
Ivermectin Effect in COVID-19 Varies With Strongyloidiasis Prevalence
Risk for mortality decreased only in ivermectin trials that took place in regions with high prevalence of strongyloidiasis
Ozone Exposure Tied to Adolescent Depressive Symptoms
Findings seen even in neighborhoods that meet national air quality standards
Living Review Compares Treatments for Atopic Dermatitis
Abrocitinib, 200 mg daily, and upadacitinib, 30 mg daily, slightly better than dupilumab, while upadacitinib, 15 mg daily is similar to dupilumab
Free COVID-19 Tests, Treatments for Uninsured Americans Cut for Lack of Funding
Program reimburses hospitals, clinics, doctors, and other service providers for COVID-19 care for uninsured people
Emergency Mental Health Visits Up After COVID-19 Surges
Findings show increases specifically for young adults and individual racial and ethnic minoritized subpopulations
Moderna Will Ask FDA to Approve COVID-19 Vaccine for Young Children
Request is based on interim results from clinical trial that showed the youngest children had an immune response similar to young adults
Decision Support System Cuts Pneumonia Deaths in Community Hospitals
Other benefits include improved antibiotic prescribing, faster time to first antibiotic
Hypertriglyceridemia Linked to Vascular Risk After Stroke
Risk of major adverse cardiovascular events increased for patients with hypertriglyceridemia even after adjustment for statin use
Patency of Iliac Vein Stents Examined in Subsequent Pregnancy
Small retrospective review shows good patency of iliac vein stents during and after pregnancy, no need for reintervention due to compression
Survival Inferior in Black Patients With Acute Myeloid Leukemia
Most disparities in acute myeloid leukemia mortality death accounted for by census tract measures
Review Explores Telehealth for Substance Use Disorders
And guideline developed to guide and inform treatment of active service members and veterans with substance use disorders
Low SARS-CoV-2 Positivity for Babies Born to Moms With COVID-19
SARS-CoV-2 positivity up in offspring in association with severe maternal COVID-19, maternal death, admission to ICU
Meds, Exercise Recommended for Stroke Prevention After sICAS
Clinicians should not recommend percutaneous transluminal angioplasty and stenting for stroke prevention