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Overall lifestyle only explained 3 to 12.3 percent of the excess risks

Every five-year younger age at onset of type 2 diabetes linked to hazard ratio of dementia of 1.24 at age 70 years

Also anticipated is a ban on menthol and other flavors in mass-produced cigars, including small cigars

No difference seen across mitral valve gradient quartiles for two-year composite end point of all-cause mortality, heart failure hospitalization

Bond offer will apply retroactively to those who have already received a COVID-19 vaccine

Surgical patients with concurrent cannabis use disorder had higher rates of inpatient neurovascular, thromboembolic, and pulmonary complications

Recommendations aim to improve postoperative pain control while reducing the risk for opioid use disorder

Almost half reported exhaustion, burnout, while one in five indicated PTSD symptoms

Failure to rescue decreased nationally from 1999 to 2017; however, disparities for five racial and ethnic groups persisted overall

Hispanic, Black children overrepresented for COVID-19 infections, but not severe disease

Odds ratios for rheumatoid arthritis increased for individuals exposed to famine in utero and at ages 0 to 3, 3 to 6, and 6 years or older

IGB therapy with lifestyle modification suggested for those with obesity who have failed conventional weight-loss strategies

Screening for hypertension with office blood pressure measurement recommended for adults aged 18 years and older

Even unvaccinated individuals may go without masks when walking, jogging, or biking outdoors with household members

European officials say AstraZeneca broke its contract when it said it would deliver only a third of the 300 million doses promised by end of June

Increased risks seen for any second cancer, obesity-related cancer, second breast cancer, second ER-positive breast cancer

Total of 615 plausible effector genes include targets of drugs approved for RA and repurposable drugs

Association only evident when adjustment was made for all vascular risk factors over the life course

Associations seen for shift work, irregular or permanent shift work, day-shift work, irregular or permanent night-shift work

Percentage positive agreement was 95 percent for BinaxNOW with virus culture for ID of replication-competent virus

Worse survival than with combination carboplatin-paclitaxel regimens for vulnerable older patients with ovarian cancer

Black and Hispanic or Latinx participants are underrepresented in clinical trials for drugs for AMD, OAG, DR

Among patients with plaque phenotype, high disease activity, and scalp lesions, 52 percent developed severe disease

Increased health care utilization seen for pediatric and adult patients

Maximum reduction in sedentary duration and increase in number of steps/day seen at week 20, attenuated by week 24

Compared with electronic health record usage at an academic medical center, clinician sex and work culture contributed more to burnout

Low-quality evidence suggests type/dose of steroid not linked to adverse psychological reactions, possibly associated with sleep problems

History of VTE predicts VTE occurrence; VTE occurrence linked to increased mortality

Three-day meeting prompted by what FDA officials call an 'unprecedented level of drug development' in recent years

When activities must be indoors, spaces should be well ventilated and windows should be kept open

In March, health system gave vaccinated workers an extra $500 and warned that at some point the shots would no longer be voluntary

No word on a timeline on when exactly tourist travel might open up or details on how it would occur

United States is 'working around the clock' to immediately send drug treatments and rapid diagnostic COVID-19 testing kits to India

In second study, bimekizumab showed noninferiority and superiority to adalimumab for moderate-to-severe disease

Local health authorities struggling to make sure that those who get their first shot also get their second

Patients with breast, prostate cancer who are receiving hormonal therapy more likely to develop cardiovascular risk factors

Worry, anxiety up with lower annual income for Medicaid-insured women receiving gynecologic oncology care during March 15 to April 15, 2020

Iron status improved in healthy pregnant women randomly assigned to Lactiplantibacillus plantarum 299v product versus placebo

Interventions investigated to reduce these adipose tissue depots, with lifestyle interventions as effective as medications (or more so)

Calcified coronary plaque prevalence lower among PLWH without known cardiovascular disease versus healthy volunteers without HIV

Mild and moderate-or-greater hearing is equivalent to 5.84 and 7.28 years of aging, respectively

Stabilization of lung function independent of the extent of quantitative radiographic interstitial lung disease or fibrosis at baseline

Past-year substance use disorder higher for adolescents than young adults at all examined time frames since first use

Johnson & Johnson has agreed with the U.S. Food and Drug Administration to add a warning label to the vaccine

Studies add to growing evidence that the two vaccines protect against all coronavirus variants identified so far

New diagnosis of psoriasis increases with age, is similar between sexes, and is greatest among Whites

Jemperli approved for dMMR endometrial cancer that progressed after platinum-containing chemotherapy treatment

Two people hospitalized; no deaths reported

22 infections identified among 12 residents and 10 staff members at 15 skilled nursing facilities; no facility-associated secondary transmission reported

Also effective against cases in South Africa, which mainly comprised infections caused by the 20H/501Y.V2 variant

Work-related musculoskeletal disorder claims from overexertion among construction workers were highest for those aged 35 to 44 years

Asymptomatic women with COVID-19 diagnosis only have increased risks for maternal morbidity and preeclampsia

New atrial fibrillation was detected in 1.5 percent of patients screened versus 0.3 percent of controls, who did not undergo screening

20-year cumulative incidence of primary open angle glaucoma was 45.6 percent after adjustment for exposure time

Minority ICH survivors have greater global cerebral small vessel disease and hypertensive arteriopathy burden on MRI

Progression-free, overall survival prolonged with sacitizumab govitecan versus single-agent chemotherapy

Hardships include forgoing care and medication nonadherence due to cost

Survival benefit seen for surgery, even with R1/R2 resection margins compared with chemotherapy alone for stage II pancreatic cancer

Increased physical activity with high exposure to air pollution may increase risk for cardiovascular disease

Adverse neonatal outcomes included preterm birth and small for gestational age; no neonatal deaths reported

The American Association for Cancer Research Annual Meeting

Data also show that pharmacies accounted for three-quarters of the reported wastage

Company emphasized that no legitimate vaccine is sold online

President asks businesses to give employees paid time off to get vaccinated, offers special tax credits to businesses employing <500 people

Mean monthly admissions for AHT in children younger than 5 were lower in 2020 than in 2019, 2018, and 2017

Those who have clinically recovered but continue to test positive on RT-PCR after the requisite isolation seem not to be infectious to others

Linear association with total CVD, all-cause mortality seen for pattern including high intakes of chocolate, confectionary, butter, low-fiber bread

Icodec results in greater increase in time-in-range versus once-daily insulin glargine U100 in two phase 2 randomized, open-label trials

Janssen adenovirus type 26 vectored vaccine may be considered for individuals who self-report PEG allergy

Cavity shave margin resections for pure ductal carcinoma in situ may lower risk for positive margins

Anti-spike protein IgG and IgA levels in breast milk significantly elevated from baseline at 80 days after maternal COVID-19 vaccination

Treatment in the morning may be more effective, with greater impact seen in MGMT-methylated patients

Authors say early cognitive interventions in childhood may lessen risk for subsequent symptoms

Best practices recommend limiting antibiotics to five days for COPD exacerbations, acute uncomplicated bronchitis

Stroke incidence higher for Black than White individuals; stage 2 hypertension tied to substantially higher stroke risk compared with normal BP

Current evidence is lacking and balance of benefits and harms of screening cannot be determined

Slightly stronger association seen for ever users of menopausal hormone therapy than never users

Findings seen in 21 countries through July 2020, including the United States

Violations included not properly disinfecting equipment, not following procedures meant to prevent contamination, improperly trained employees

When supply exceeds demand, finding willing arms to receive vaccines gets a lot harder

Findings show highest risk in the first four months post-TBI, but risk remains regardless of severity or type of injury

Testing for antibodies to platelet factor 4 positive in 22 of 23 patients; treatment with platelet transfusion should be avoided

However, Black women have COVID-19 mortality rates nearly four times higher than White men, three times higher than Asian men

Lengths of stay even longer with discharge to a skilled nursing facility or rehabilitation center

Diagnostic yield for SARS-CoV-2 cardiac involvement higher for clinically indicated versus primary screening cardiac MRI

Total and measles-containing vaccines declined markedly in all children but recovered in those aged 0 to 23 months

Cutaneous immune-related adverse events seen in 25 percent of cancer patients initiating ICI therapy with median onset time of 113 days

Risk particularly high for acute myeloid leukemia before age 5 years

FDA granted Opdivo first approval of immunotherapy for first-line treatment of advanced or metastatic gastric cancer

Authors suggest MRI-based subtypes could predict disease progression and help target treatments

Variable impact found on changes in process measures, with no improvement in clinical outcomes

Racial income differences were statistically significant each survey year, with difference of $50,000 in 2018

Most common pain locations were back and hip, knee, or foot; physical therapy and massage most often used for management

European Medicines Agency also said the vaccine's benefits still far outweigh its risks

Airborne transmission of the virus continues to be the major threat

Nation is close to meeting President Biden's goal of 200 million shots in arms by his 100th day in office

Risk for testing positive reduced with use of probiotics, omega-3 fatty acids, multivitamins, and vitamin D supplements for women

Decrease seen in long-term residential care with admission avoidance hospital at home with comprehensive geriatric assessment

After adjustment for maternal sociodemographic, prepregnancy, pregnancy, and perinatal covariates, no link found with autism spectrum disorders

Among healthy, young adults, risk for subsequent infection among seropositive participants about one-fifth of that for seronegative participants

CDC added that almost 84 million adults, or nearly a third, are fully vaccinated

Prevalence varies by race/ethnicity, ranging from 17 percent among Whites to 65 percent among American Indian/Alaska Natives

Women, Black or Asian patients less likely to receive sodium-glucose cotransporter 2 inhibitor treatment for type 2 diabetes

Within two to four months, increases, decreases in systolic BP seen in transmasculine, transfeminine adults, respectively

Adverse ventricular remodeling, poorer cardiac function, and higher arterial stiffness linked to greater intake of red, processed meat

Some life habits and socioeconomic factors such as alcohol consumption, smoking, relationship status, physical activity may also contribute

Cumulative hazard of death increased in association with hemorrhagic stroke, but not with ischemic stroke

Vaccination differences represent a large percentage of Black and Hispanic gaps in vaccination rates

BCDR had high sensitivity, specificity based on body region bruised, bruising anywhere on infant 4.99 months or younger, bruising pattern

While not required, a third booster shot could provide additional protection against COVID-19 variants

Correlation of migraine or severe headache with IBD remains significant overall after adjustment for all covariates

All projects that had been approved before the Trump administration restrictions 'will be reinstated without further review'

Actual number believed to be much higher because some governments may be concealing numbers

Officials have not said how low COVID-19 case numbers must go or how many people would have to be vaccinated for the requirements to be lifted

And, CDC has scheduled a new emergency hearing on the safety of J&J vaccine for April 23

WHO wants to emphasize the need for Europe to maintain social distancing and speed up vaccinations

In addition to increased risk for death, hospital and ICU lengths of stay are longer

o,p'-DDT exposure in normal-weight, but not overweight or obese, grandmothers linked to obesity in granddaughters

Clinical indication and individual risk factors linked to breast cancer detection and could help triage mammography use

About 43 percent of patients who receive anti-PD1 therapy for advanced melanoma have chronic immune-related adverse effects

Stress-related brain activity tied to higher risk for developing Takotsubo syndrome

Future increase in morbidity and mortality rates likely as younger generations age

Those with severe mental illness also less likely to receive revascularization

Evidence-based guidelines address diagnosis, evaluation, and treatment, including early multidisciplinary care team involvement

Online ratings perceived to be very important nearly as often as word-of-mouth recommendations from family and friends

Number of self-identified preventive medicine physicians has decreased since 2000, with leveling off in past four years

Authors say screening and linkage to supportive services needed for HIV patients

Neutralizing antibody titer is higher after one dose of mRNA vaccine than after two vaccine doses in previously uninfected persons

Waiver could open the door for generic or other manufacturers to make more vaccines

No difference seen in change in depression scores at six weeks for psilocybin plus placebo versus psilocybin plus escitalopram

Discontinuation of oxytocin may lead to small increase in rate of cesarean section, decrease in fetal heart rate abnormalities

Children with neurological involvement have higher peak inflammatory markers, are more likely to be ventilated

B-cell repopulation occurs more often in African American versus White patients between six and 12 months after anti-CD20 infusion

Findings independent of socioeconomic characteristics, onset age, and other related disorders

Cortical thinning partially mediates the association between neighborhood-level disadvantage and cognitive decline

Increased risks for anxiety, depression, adjustment disorder especially high during first two years after diagnosis

Nonpharmaceutical interventions to reduce COVID-19 associated with reduction in admissions for COPD, asthma

Consuming more than 50 mg of caffeine per day (the amount in about half a cup of coffee) linked to lower birth weight

Emergency department visits were 25 percent lower during December 2020 to January 2021 versus one year earlier

However, mammography and colonoscopy rates rebounded substantially by the end of July

Increase largely driven by illicitly manufactured fentanyl and other synthetic opioids

New data are the first to indicate how effective COVID-19 vaccines are in real life

Advisers to the CDC say they do not have enough information or time to recommend how to proceed and they will meet again within 10 days

Among women, suicide incidence was higher among nurses than the general population, with relative risk of 1.99

Evidence insufficient to ascertain benefits and harms of screening for vitamin D deficiency in asymptomatic adults

Second study shows no change in symptoms, disease duration, reinfection rates with B.1.1.7, but reveals multiplicative increase in R₁

Geographic and temporal differences ID'd in racial and ethnic disparities in COVID-19 hospitalization levels during 2020

Infected adults regularly meeting physical activity guidelines have lower risk for hospitalization, death

Animal foods, sugar, processed foods tied to inflammatory gut microbiome, while plant-based foods tied to anti-inflammatory microbes

Authors say that it is important for providers to assess sleep patterns in patients with schizophrenia

Workers in construction, manufacturing jobs may be more susceptible to carpal tunnel than those working in office jobs

Hazard ratio for mortality was 1.75 for community-dwelling adults aged 40 to 85 years colonized with MRSA

Elexacaftor/tezacaftor/ivacaftor well tolerated in children aged 6 through 11 years with cystic fibrosis and at least one F508del-CFTR allele

Obesity associated with an estimated excess annual medical cost of $1,861 per person among U.S. adults

Compared with prepandemic period, increases seen in risk for firearm injuries in young children and injuries inflicted by young children

In 2019, nearly 2.5 million Americans had an infection of chlamydia, gonorrhea, or syphilis

Company also says vaccine is 95 percent effective against severe cases of the disease

Ban forced Planned Parenthood out of the federal family planning program called Title X

Agency said it will assess the science, set maximum acceptable levels, and monitor baby food makers' compliance

Reports document 16 reactions in young European patients following first dose of ChAdOx1 nCoV-19 vaccine

Most neonates fed unpasteurized expressed breast milk until discharge; 85 percent were breastfed postdischarge

Higher levels of leisure time, but not occupational, physical activity associated with decreased risk for cardiovascular events, death

Significant reduction found in risk for disease progression/death for C+R versus placebo and rituximab

Better work environment associated with fewer readmissions and shorter length of stay

Concurrent rise seen in fall-related mortality in older adults in the United States from 1999 to 2017

Diagnosis of TES requires exposure to repetitive head injury, core features of cognitive impairment/neurobehavioral dysregulation

Lower risk seen for major CVD, mortality with a minimal fish intake of 175 g (approximately two servings) weekly in those with vascular disease

Recommendation strong for screening average-risk individuals from age 50 to 75 years; recommendation conditional for screening from age 45 years

The six cases involved a cerebral venous sinus thrombosis and occurred in women between the ages of 18 and 48 years

Authors recommend postponing surgery for patients with positive preoperative COVID-19 test result

From 2005 to 2014, the ratio of Medicare reimbursements for hospital charges compared with surgeon charges has increased

Agency says wild animals 'are the source of more than 70 percent of all emerging infectious diseases in humans'

Decision means that health care providers in some states will be able to prescribe mifepristone via telemedicine and mail the pills to patients

Two people have been hospitalized, but no deaths have been reported

The GI Genius identifies 'regions of interest' in real time to help clinicians determine where further assessment may be needed

Most common were delayed large local reactions, followed by local injection site reactions, urticarial eruptions, morbilliform eruptions

However, anticoagulation cuts risk for major thromboembolic events by 46 percent

Response is lower than for individuals without kidney disease, and age affects response regardless of medical conditions

Ban could reduce the number of melanoma cases and decrease lifetime health care costs, despite compliance costs

Vaccine well tolerated in 13 patients; vaccine showed potential benefit in patients with solid tumors, multiple myeloma in phase 1 trial

But adherence to healthy lifestyle not associated with decreased risk for overall prostate cancer

Increased exposure linked to significantly increased rates of incident keratinocyte carcinoma, melanoma in adults ≥66 years

Mortality risk lower with PDE5i treatment versus alprostadil treatment; similar links seen for MI, heart failure, CV mortality risks

Heartburn, regurgitation symptoms, particularly daytime regurgitation/reflux, may help identify patients with rumination syndrome

Currently, the FDA allows the Pfizer vaccine to be given to people 16 years and older

Acute CRAO is a medical emergency and patients should be immediately triaged to an emergency department

Drug company will ask FDA to expand the drug's EUA to allow it to be given for preventive purposes in 'appropriate populations'

Fakespot, which identifies online retail scams, has pinpointed hundreds of different sellers of fake vaccination cards since the start of the year

Effectiveness of one vaccine at preventing symptomatic infections was found to be as low as 50.4 percent by researchers in Brazil

Greater efforts needed to increase diversity in health care professions

Decrease seen despite concerns there would be more suicides due to the COVID-19 pandemic

Risk reduction even greater for obesity-related cancers

And, North Carolina has stopped administering Johnson & Johnson vaccines after at least 26 people experienced adverse reactions

Prescription rates for psychotropic drugs during adolescence, young adulthood higher with preterm birth versus birth at term

Female recipient received lung tissue donated by her husband and son

Unmarried, less-educated patients less likely to receive autologous hematopoietic cell transplantation

Agency says the risk for contracting the virus from a contaminated surface is less than 1 in 10,000

Age, sex, smoking status, 10-year atherosclerotic risk score, and natriuretic peptide concentrations tied to future cancer risk