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Five circulating microparticle proteins differentiated placenta accreta spectrum from controls using plasma samples at median of 26 weeks of gestation

No increase seen in resident applications despite a very significant increase in integrated plastic surgery residency positions from 2010 to 2018

Independent associations seen and validated in two cohorts of children living in urban areas

Authors say this has implications for customization of over-the-counter hearing aids

Improving adherence to healthy lifestyle inversely associated with colorectal cancer risk

Approval of Leqembi comes after controversial approval in 2021 of Aduhelm, which met with criticism over concerns about that drug's effectiveness, safety, pricing

Racial disparities seen in outcomes, including more cases in Black children as organ dysfunction increases

Noninferiority established with respect to time to sustained clinical recovery for adults at high risk for progression

Recovery faster in terms of 2-minute walk test, Timed Up-and-Go test for unicompartmental versus total knee arthroplasty

Authors recommend against clinical assessment alone when neuromuscular drugs are administered due to insensitivity of assessment

Non-Hispanic Asian children and adolescents have the highest vaccination coverage, followed by Hispanic/Latino children

2.3 percent of all reported mpox cases were in cisgender women, 44 percent of whom were non-Hispanic Black

Larger benefit seen among those aged 13 years or older or with a mental illness, depression diagnosis

Increase in vaccination rate linked to fewer COVID-19 cases and deaths among residents, cases among staff

Intervention to increase social work staffing on primary care teams serving rural veterans tied to increased use of palliative care following hospitalization

Worse outcomes seen for mental health, pain, unhealthy lifestyle behaviors, and psychosocial health factors

Modified Atkins diet added to standard drug treatment more effective for reducing seizure frequency than standard drug therapy alone

Significantly higher association between diabetes and VTE seen among women versus men, especially those aged 50 to 59 years

Text message-based platform enhances self-efficacy for managing symptoms of IC/bladder pain syndrome

Nomogram showed good discrimination, with areas under the curve of 0.806 and 0.831 in training, validation cohorts

Risk for obesity higher for children in areas of low socioeconomic status

Significant increase seen in detection of flat adenomas with Paris classification 0 to IIb in patients with Lynch syndrome

High satisfaction reported for addressing medical and social concerns in primary care

Inverse relationship seen between habitual nighttime hot spring bathing and history of hypertension

Most prominent increase seen for spouses of patients diagnosed with cancer with poor prognosis, at advanced stage

Significant effects seen for treatment condition and time for participants who used Bio Ware during one or more IVEs

Risk for severe outcomes of COVID-19 higher for patients with hematologic versus solid cancer

Lipid testing provided in only 2.8 percent of ob-gyn preventive visits

Incompletion of reconstruction tied to tissue expander complications, high body mass index, radiation therapy

Magnitude of the association increased with the number of antiepileptic drugs prescribed

When comparing pre-COVID-19 years with COVID-19 years, significant increase seen in both ICU and non-ICU admissions

Elevations in creatine phosphokinase had sensitivity and specificity of 99 and 23 percent, respectively, for identifying myocarditis

Increased risk for developmental delay, intellectual disability, and epilepsy/intellectual spasms observed for those exposed to T1DM

Those with current alcohol use disorder or abstinent with alcohol use disorder history had lower likelihood of receiving direct-acting antivirals

Image model, video model, ensemble model were all superior to standard fetal biometry-based gestational age estimates

Psychiatric capacity structurally inequitable along both income gradient and rurality

Patients will still need a doctor's prescription to access the drugs, and pharmacies must follow certain rules to dispense the medication

Correlation of PHQ-2 scores with neutrophil count greater and significant only for women

Increased odds ratios seen for advanced liver fibrosis with age older than 50 years, BMI >30, diabetes, hypertension, dyslipidemia, metabolic syndrome

Graded association observed between smoking and subjective cognitive decline, with greatest prevalence seen for current smokers

Assuming trends from 2002 to 2017 continue, increases of 65 and 673 percent expected in types 1 and 2 diabetes, respectively, to 2060

WTC model allows for personalized drug testing within 10 days, even for small-sized tumors

No significant moderators identified for the association, possibly due to small number of studies included

Those with middle-age serum sodium >142 mmol/L also have increased risk for developing chronic diseases, premature mortality

Serious adverse events are rare, occur more often with mifepristone-misoprostol versus procedural induced abortion in first trimester

Bisphosphonates strongly recommended for initial treatment of primary osteoporosis for postmenopausal women

Occurrence of major cardiovascular events, non-cancer-related deaths no lower with chlorthalidone versus hydrochlorothiazide

180-day hospitalization risk significantly increased following endocarditis for those with opioid use disorder, cocaine use disorder

Longer progression-free survival seen with zanubrutinib versus ibrutinib for patients with relapsed or refractory chronic or small lymphocytic leukemia

No significant difference seen in likelihood of worse outcome in adjusted analysis for methylprednisolone versus placebo

All sequenced A(H3N2) viruses belonged to genetic group 3C.2a1b subclade 2a.2, which was antigenically different from 2021-2022 vaccine component

Adjusted composite patient rating of specialist care higher in association with cotraining of PCPs and specialists

Minor adverse events seen in 48.6 percent of patients, most often arm soreness and/or fatigue

Teens with habitual social media checking behaviors showed lower neural sensitivity to social anticipation in amygdala, other areas

Trial funded by the NCI has prompted the FDA to approve Tecentriq for children and adults with alveolar soft part sarcoma

Small reductions in pain-related disability at three months for multidisciplinary biopsychosocial intervention, individualized postural therapy

Highest reported unaffordability seen for dental care, followed by prescription drugs, medical care, mental health care

Risk for congenital hearing loss increased for those with petechiae at birth, periventricular cysts on MRI, seroconversion in first trimester

Immunoglobulin G spike receptor binding domain antibody levels similar after primary series, booster dose

However, improvements not significantly better than those seen with sham acupuncture

Nearly half have alcohol use disorder, symptoms of alcohol-related harm, or alcohol-related problems at eight years after surgery

Based on inverse variance weighted method, GERD found to substantially increase lung cancer risk

Authors strongly recommend treatment with denosumab or an intravenous bisphosphonate for adults with HCM

Adults with neuroendocrine tumors value independence as most important, with most valuing their future versus current quality of life

Strong recommendations include use of glucagon preparations that do not need reconstitution, real-time CGM for those receiving multiple daily injections

Clinical practice guidelines can help detect IBI in infants aged 8 to 60 days with high sensitivity but low specificity

Normalized difference vegetation index negatively associated with hospitalization for Alzheimer disease and related dementia, Parkinson disease

All with data available were at least partially unvaccinated, having had no doses or just one dose of the two-shot MMR vaccine

Findings for pneumococcal vaccine among immunosuppressed rheumatology patients

There have been 44 reports of carbon monoxide emission from customers, including three reports of people needing medical attention

Sunlenca is the first capsid inhibitor approved for HIV

The new rule, set to go into effect on Jan. 5, was created in response to a surge in COVID-19 cases in China

Nearly twofold increase in annual number of attacks seen from 2016 to 2021, exposing information of nearly 42 million patients

Self-reported failure to have understanding of treatment linked to failure to meet treatment expectations

Minimal difference observed in total costs and effectiveness after one year of follow-up

Patients with GERD have increased risk in analyses stratified by age, sex, and presence or absence of comorbidities

No reduction in COVID-19-associated hospitalizations or deaths seen among high-risk, vaccinated adults

Opiate prescriptions predicted by primary care physician specialty and patient age, gender, race

Furthermore, Black patients more likely to experience major complications, death than White patients

Astigmatism ≥1.0 D in both parents associated with greater odds of refractive and corneal astigmatism in the child

Findings similar across race/ethnicity and prepregnancy body mass index, but stronger in women aged 35 years or older

Magnitude of association for finasteride and dutasteride with dementia decreased over time and became nonsignificant

Mpox cases that occurred in vaccinated individuals associated with lower percentage of hospitalization

Only about 5.7 percent of patients receive incorrect diagnosis, with about 2.0 percent suffering adverse events as a result

Controversy over Aduhelm stretches back to its June 2021 approval by the U.S. Food and Drug Administration

No hospital-level factors (e.g., region, size) were associated with conducting screening

Social frailty linked to composite of all-cause death, cardiovascular events among elderly hospitalized heart failure patients

Predictors of emergency department avoidance include lower income, being uninsured, poor or fair mental/physical health, and younger age

Findings seen even among patients who have already progressed to high-risk portal hypertension

However, natural immunity tied to lower incidence of new infection

Higher dietary nitrate intake linked to reduced risk for progression to late age-related macular degeneration

Slowing of disability progression and higher likelihood of disability improvement observed compared with standard disease-modifying therapies

Outcomes worse for Black versus White patients enrolled in clinical trials that minimize access to care, socioeconomic status confounders

Radiation therapy recommended to reduce risk for vaginal and/or pelvic recurrence; data limited for sequencing radiation therapy and chemo

Primary outcome event occurred in more infants in the early-ibuprofen group than the expectant-management group

Apixaban dominated enoxaparin and edoxaban; rivaroxaban was slightly more effective than apixaban

AI had overall accuracy of 79.5 percent and passed two of 10 mock Royal College of Radiologists exams when excluding noninterpretable images

New revised leaflets now clearly state that Plan B and its kin work 'before release of an egg from the ovary'

Increase in annual attributable costs observed over time, from $28,311 in 2007-2013 to $37,055 in 2014-2017

No association seen between mean negotiated price and TJA complication rate, readmission rate, hospital performance score

Pediatric mental health visits with length of stay >12 and >24 hours accounted for 20.9 and 7.3 percent of all visits

Vast majority of cancers diagnosed due to symptoms or other medical care

Four children have become trapped in the blankets, including a 4-year-old girl and a 6-year-old girl who both died

Psychiatric comorbidities, chemical restraint use, public insurance tied to emergency revisits; substance use disorders associated with lower likelihood of revisits

Model performed five-way classification with 79 percent accuracy in 14 seconds on 100 test images

Findings show dose-response relationship, with higher risk tied to more severe atopic dermatitis

Systematic review finds acupressure better than acupuncture or electroacupuncture

Implementation of on-site guideline-based genetic testing for prostate cancer patients increased compliance from 33.3 to 98.7 percent

Higher risk seen with increasing peritonitis episodes; risk for cardiovascular mortality lower for those commencing peritoneal dialysis in 2012-2019 versus 2003-2011

Vestibular migraine plays key role in precipitating PPPD as a single comorbidity or component of multiple vestibular comorbidities

Adults with prior history of osteoporosis have increased risk of Ménière disease and those with prior Ménière disease have increased risk of osteoporosis

In two years following a rural hospital closure, nearby hospitals see increase in emergency department visits and hospital admissions

Treatment-resistant depression episodes tied to more psychiatric comorbid conditions, health care utilization, self-harm, and all-cause mortality

Mexican American adults receiving insulin less likely than non-Hispanic Whites to achieve glycemic control

New requirements are so strict that it costs less to add sesame to food products than to try to keep it out

Significant increases seen among children who are Black, very young, and with public insurance

Age-specific deaths rates increased for all age groups 1 year and over; no significant change seen in infant mortality rates

More patients receiving dupilumab have histologic remission, improvement in Dysphagia Symptom Questionnaire scores

Alcohol as trigger occurred more often in men; lack of sleep as trigger more common in women

Patients, caregivers scored higher on AML knowledge and perceived greater efficacy in communicating with oncologists

Findings for both 25-hydroxyvitamin D deficiency and insufficiency

Emergency surgery associated with incomplete oncologic evaluation, and increased incidence of postoperative complications, including mortality

Children ≤10 years often victims perpetrated by parents/caregivers, while children ≥11 years more often perpetrated by friends/acquaintances

No significant association observed between average annual emergency department volume and restraint use

Moderately-to-severely decreased eGFR had significant effect on all-cause mortality specifically in those with low socioeconomic status

Deep learning, multidiagnostic model shows high accuracy before clinical examination

No benefit seen for episodic memory or executive function at six or 18 months for older adults

However, no association seen between racial/ethnic group and patient satisfaction

Multiparametric flow cytometry has excellent prediction for survival among patients with B-cell acute lymphoblastic leukemia

Volume of endolymphatic hydrops decreased with reduction of vertigo attacks during eight months of PPT plus medication; however, volume increased with medication alone

Decision comes as the nation suffers from an unusually early and hard flu season, with about 9,300 deaths so far

Bivalent booster is effective against COVID-19 hospitalization in immunocompetent adults, seniors

1.55 percent difference in utilization rate for CT contrast media between localities with 10 percent different in NPP evaluation and management share

Does not reduce risk of relapse overall, but can reduce relapse risk and manic symptom severity for low-risk individuals

However, trend offset by increase in advanced practice professionals weekly work hours

No association seen for people with optimal and normal BP, high-normal BP, grade 1 hypertension

Among non-Hispanic Whites, highest incidence rates seen in Northeast for bladder cancer, Appalachia for kidney cancer

Increase in rate of injuries seen among elderly adults; head was most commonly affected body part

No significant difference observed in terms of tongue coating scores, plaque index for those receiving probiotics

Higher frequency of practice tied to greater impact on self-reported symptoms

Median survival significantly shorter for patients with renal impairment versus those with no renal impairment

Findings seen among subgroup of patients with human epidermal growth factor receptor 2-positive metastatic breast cancer

Risk varies by type of distress, but significant relationships seen for exhaustion and stress

Higher rates seen in less competitive markets and facilities that are large, for-profit, and non-safety net

Performance of lumbar puncture has decreased in late-onset sepsis evaluations; 16 percent of late-onset meningitis cases occurred without late-onset sepsis

Electronic nicotine delivery system use tied to gum bleeding

Variation seen in accessibility to mammography by states; in 10 states, more than 26 percent of women aged 45 to 84 years had limited access in 2022

Medication limits are meant to 'ensure equitable access,' according to a CVS statement

No evidence that large numbers of nurses left health care or hospital practice during first 18 months of pandemic

Experts recommend agency leaders set clear objectives and expectations to prevent more 'detrimental’ effects on the agency's work and staff morale

The 64th American Society of Hematology Annual Meeting and Exposition

When clinical symptoms and signs of hypothyroidism are present, TSH, free thyroxine should be measured, regardless of screening results

Hazard of incident diabetes reduced by 44 percent in adjusted models comparing average daily step count of 10,700 to 6,000

No difference seen in global PET amyloid burden between asymptomatic with Down syndrome, asymptomatic mutation carriers

SARS-CoV-2 coinfection occurred in 6 percent of pediatric influenza-associated hospitalizations

Cumulative environmental risk score most strongly associated with true schizotypy, followed by affective, introverted schizotypy

Most of the cancer survivors who refused participation in a trial of the vaccine did so for vaccine-related concerns

Reduced risk seen for total knee replacement and total hip replacement with metformin use

39 percent of patients had a complete response, with median time to complete response of 42 days

Brain abscesses where no primary source of infection identified have higher counts of Streptococcus anginosus

BP reduction greater with 15 minutes a day of yoga, five times a week for three months plus 30 minutes of aerobic training, compared with stretching control

Most direct-to-consumer platforms offer testosterone therapy despite consumer reporting normal testosterone levels, free testosterone

About 90 and 83.9 percent of overdose deaths involved opioids and illicitly manufactured fentanyls

Addition of left atrial reservoir strain also yields predicted net benefit in people without prior a-fib or stroke

DART improves decisional quality at three and six months; results decrease thereafter

However, early electronic cigarette quitters plus stable cigarette use was the most common trajectory in 41.6 percent of participants

About 57,000 men and 18,000 women are diagnosed with bladder cancer annually

Four changes included in new case definition, including no required duration of subjective or measured fever

Only peak force fatigability, but not peak rate of force development, contributed to fatigue variance

The 45th Annual CTRC-AACR San Antonio Breast Cancer Symposium

FMT from lean donor does not reduce body weight, improve results of bariatric surgery at six months or one year

Different patterns of age-specific incidence observed between countries with and without well-developed population-based screening and treatment

Right thumb network achieved highest level of accuracy from networks based on single fingers at 68 percent

Authors say mobile devices for calming should be avoided in preschool-aged boys, children with higher surgency

Among those with atopic dermatitis, smoking and male sex were significantly associated with higher risk for new-onset migraine

Authors say systematic inflammation likely contributes to increased incidence of PAD in this population

Among participants with episodic migraine, the interaction of migraine presence on day 2 with alcohol intake on day 2 not significant

Being married, having a confidant associated with better mental health with COPD

Immediate increase seen in vaccine administration rate in women; increased slope seen over time postupdate

Prevalence of obesity with type 2 diabetes highest in White children and lowest in Asian children

More adverse dental outcomes seen with sublingual buprenorphine/naloxone compared with use of transdermal buprenorphine or oral naltrexone

Highest risk for thyroid cancer seen among participants with both high genetic risk and unfavorable lifestyle

Higher risk seen among women drinking one or more beverages per day

Black men disproportionately impacted by firearm homicide, while White men most impacted by firearm suicide

No association seen with death, major adverse cardiovascular events, rehospitalization following elective major noncardiac surgery

Extended method uses additional data from 1999 to 2016 NHANES, rather than extrapolation; improves characterization of extremely high BMI in children

Presence of RLS associated with significantly more severe psoriasis and more severe systemic inflammation

Twelve instruments were selected to measure outcomes in the value-based outcome set, which were reported by patients and providers

Lasting improvement seen for patients receiving anti-OX40 antibody rocatinlimab compared with placebo

Altered smell and taste are significant predictors of positive anti-spike IgG response in multivariable models

Locus of control appears to modify the effect size of work stress on stroke risk

Findings show fewer years free of disease at all ages compared with the general population

Vending machine dispenses naloxone, sharps containers, safer injection/smoking kits, pregnancy tests, HIV tests

However, recovery seen in monthly volume of vaccine doses administered

Recommendations include duplex ultrasound scanning as diagnostic test of choice; venous intervention over long-term compression stockings

These social media messages build positive attitudes, which are tied to intention to vaccinate

Children exposed to maternal schizophrenia have increased risk for mental health and non-mental health conditions

COVID-19 will remain the third-largest killer for 2022, behind heart disease and cancer, even with the reduced numbers

Every household in the country is eligible to receive four free COVID-19 nasal swab testing kits