FDA Tells Three Small E-Cigarette Makers to Stop Selling Flavored Products

Agency says companies have not provided 'sufficient evidence' that any possible public health benefits of e-cigarettes outweigh the risks

Fratelli Beretta Antipasto Trays Are the Source of Salmonella Outbreak: CDC

Agency says investigation is continuing to try to determine if additional products are linked to the outbreak

FDA Approves First Nerve-Stimulation Device to Aid Stroke Recovery

Vivistim System is a prescription therapy for ischemic stroke patients who have moderate-to-severe difficulty moving their arms and hands

Half of American Workers Support COVID-19 Vaccination, Mask Mandates in Workplace

Poll was conducted before the FDA granted full approval to the Pfizer COVID-19 vaccine

Adverse Events Associated With BNT162b2 Vaccination ID’d

Vaccination not associated with elevated risk for most of the adverse events examined; association found with increased risk for myocarditis, but risk higher in association with SARS-CoV-2 infection

Adults With Disabilities Have Worse Mental Health During COVID-19

Adults with disabilities more often report that the pandemic makes it harder for them to access care, medication

Risk Factors ID’d for Lower-Limb Amputation for PAD in Urban Areas

In metropolitan areas, lower median household income and higher Distressed Communities Index score tied to increased amputation rate

Current, Recent SARS-CoV-2 Infection May Up VTE Risk After Surgery

Substudy of prospective cohort study shows link between SARS-CoV-2 infection and increased risk for postoperative venous thromboembolism

Magnets in Consumer Electronics Can Interfere With Medical Devices

In close proximity (1 to 11 mm), static magnetic fields created by iPhone 12, Apple Watch 6 models can interfere with pacemakers, ICDs

Dementia Risk Score Linked to MRI Markers of Brain Atrophy

Higher scores on Lifestyle for Brain Health index linked to higher volumes of white matter hyperintensities, lower scores for cognitive function

Most Children Experience Fluctuations in ADHD Symptoms

While nearly one in three will experience points of remission of ADHD symptoms, most experience recurrence over time and few outgrow it

Vitamin D Does Not Impact Kidney Outcomes in Prediabetes

Secondary analysis of randomized trial shows no difference in progression of KDIGO risk scores with daily vitamin D versus placebo

Home Hospital Model Creates Capacity, Delivers Quality Care

Findings show model can successfully free up hospital beds by treating some patients at home during a pandemic

Reading Clinic Visit Notes Benefits Older Adults

Older adults with chronic conditions report reading notes helped them to remember their care plan, medications

Learning Environment Issues Tied to Medical School Burnout

Those reporting mistreatment may also experience exhaustion, disengagement, and career regret

Moderna Readies for Full Vaccine Approval, as Pfizer Submits Data on Booster Shot

Right now, Moderna vaccine only authorized for emergency use in Americans 18+ years; Pfizer boosters available to immunocompromised

Record High COVID-19 Cases and Deaths Reported in Florida

As of Tuesday, Florida had reported a record average of 227 COVID-19 deaths a day this week

WHO Team Says Search for Coronavirus Origins at Standstill

Agency published an analysis in March that concluded the virus likely jumped to humans from animals

SARS-CoV-2 Shot Continues to Prevent Infection, Hospitalization With Delta Variant

SARS-CoV-2 infection rate and hospitalization rate 4.9 and 29.2 times higher for unvaccinated versus fully vaccinated persons

Breast Density Linked to Risk for Invasive Breast Cancer in ≥65s

Risk for invasive breast cancer increased with increasing breast density for women aged 65 to 74 years, 75 years or older

Some High-Priority Groups More Likely to Stop Taking PrEP

Younger individuals, African American and Latinx, those with substance use disorders more likely to discontinue PrEP

State Limits on Initial Opioid Rx Duration May Influence Prescribing

Decreases in days of opioid prescribed for initial prescriptions in Medicare beneficiaries especially pronounced among surgeons, dentists

Outcome Measure Developed for Crohn’s Perianal Fistula

Crohn's Anal Fistula QoL has good internal consistency, excellent stability, good responsiveness and construct validity

1990 to 2019 Saw Doubling of Number of People With Hypertension

Treatment and control rates vary, with largest improvements in high-income countries, some upper-middle-income countries

SARS-CoV-2 Vaccine Effectiveness 66 Percent During Delta Predominance

Vaccine effectiveness for all three vaccines decreased from 91 percent in months preceding delta predominance

Suicide Ideation Rates Reduced Among Veterans During COVID-19

Risk factors for new-onset suicide ideation include low social support, lifetime PTSD and/or depression, worsening of social relationships

Rates of Obesity, Weight Gain Up for Transmasculine Individuals

Prevalence of obesity and weight gain higher after hormone therapy for transmasculine versus transfeminine individuals

Nephrology Referrals ID Many Patients at Low Risk for Progression

Potential referral volume could be reduced if referral was restricted to patients with predicted risk ≥1 percent in addition to laboratory criteria

One in Four Older Adults Not Asked About Alcohol Use

Authors say physicians should screen and counsel older adults on alcohol use

Psoriatic Arthritis Worsens QoL in Patients With Psoriasis

Individuals with psoriasis/PsA have decreased ability to participate in social roles and activities, more depression symptoms

J&J Says Booster Shot Ups Immune Response to COVID-19

The Johnson & Johnson vaccine was not part of the government's initial booster plan, announced last week

Risk for Bell Palsy Up 42 Days After First Dose of CoronaVac

Hong Kong study shows small increased risk after Sinovac Biotech vaccine, but no significantly increased risk after BNT162b2 vaccine

Pentagon Says Troops Must Start Lining Up Now for COVID-19 Shots

The Pfizer vaccine will be added to the list of required shots for U.S. troops

Survival Rates Lower for Black Liver Transplant Recipients

For Blacks versus Whites, differences in post-LT mortality narrowed between 2002 and 2009, increased between 2014 and 2018

SARS-CoV-2 Antibodies ID’d in Breast Milk of Vaccinated Lactating Women

After the second dose of mRNA COVID-19 vaccine, breast milk levels of IgG(S1) increased and correlated with corresponding serum levels

Liraglutide Reduces Visceral Fat in Overweight, Obese Adults

Liraglutide plus diet and physical activity counseling reduce visceral and ectopic fat in overweight, obese adults at high risk for CVD

Maternal Obesity May Up CRC Risk in Adult Offspring

Authors say this association may be contributing to increasing incidence rates of colorectal cancer in younger adults

Mishaps Common During Patient Transport From Emergency Care

Common risk events during intrahospital patient transport from ED included limb trapping/displacement, collisions, IV line or catheter issues

Donor HLA Evolutionary Divergence May Predict Liver Transplant Rejection

Class I HED of the donor is associated with higher risk for acute and chronic rejection of the liver transplant

2001 to 2017 Saw Increase in Prevalence of T1DM, T2DM in Youth

Relative increase of 45.1 percent reported in prevalence of type 1 diabetes and relative increase of 95.3 percent reported in type 2 diabetes

No Benefit Found for COVID-19 Convalescent Plasma in High-Risk Outpatients

Disease progression was not reduced with convalescent plasma for outpatients aged 50 years or older with one or more risk factors

More Than 10 Percent of Adults Missed Health Care in Spring 2021

In addition, 9.2 percent of parents report delaying or forgoing care for their children for fear of exposure to the coronavirus

Cycling Common Cause of Sports-Linked Traumatic Spinal Injury

Within sports-related TSIs, rate of spinal cord injury was 13 percent for cycling injuries versus 41 percent for contact sports

Alcohol Use Down, Nicotine Use Up for Teens During COVID-19 Pandemic

Likelihood of using substances up when youth were stressed by pandemic-related uncertainty, family experienced material hardship

Morbidity Risk Up Among Black and Hispanic Term Newborns

More Black and Hispanic women deliver in hospitals ranking in the highest-morbidity tertile compared with White, Asian American women

FDA Warns Against ‘Off-Label’ Use of Pfizer COVID-19 Vaccine in Younger Children

Adult vaccine dose is much higher than doses being tested in younger children

Pain, Fatigue, Depression, Anxiety Prevalent After MS Diagnosis

Most patients had co-occurring symptoms: 21.3, 19.1, and 17.4 percent had two, three, and four symptoms, respectively

Salmonella Illness in 17 States Tied to Salami, Prosciutto

Twelve people have been hospitalized; no deaths have been reported

Poverty Tied to Worse Functional Status in Rheumatoid Arthritis

Patients with lower socioeconomic status also have increased probability of functional decline in longitudinal analyses

Factors Linked to Development of Pediatric Psoriasis Identified

Factors independently linked to development include atopic dermatitis, family history of psoriasis, skin and fungal infections

USPSTF Says Start Diabetes Screen at Age 35 for Those With Overweight, Obesity

Overweight or obese adults should be screened for prediabetes, type 2 diabetes and offered or referred for preventive interventions

Teens, Young Men Have Higher SARS-CoV-2 Infection Rates

Standardized infection ratios were lowest in children and in adults aged 70 years or older compared with overall population

Risk for Death Increased for Infants After Maltreatment Report

Increased risk for death attributable to medical causes for infants reported for alleged maltreatment

More Frequent Alcohol Consumption Ups Risk for GI Cancers

Amount of alcohol consumed in each occasion seems to be a less important risk factor

COVID-19 Mortality Lower for Vaccinated Solid Organ Transplant Recipients

Second study shows increased risk for breakthrough COVID-19 infection and associated mortality for SOTRs versus general population

Roxadustat Treats Anemia in Non-Dialysis-Dependent CKD

Pooled data show roxadustat versus placebo increases hemoglobin levels with an acceptable profile for cardiovascular safety

Guidance Issued for Colonic Volvulus, Acute Colonic Pseudo-Obstruction

Clinical practice guideline addresses diagnosis and management of colonic volvulus, acute colonic pseudo-obstruction

Pfizer-BioNTech COVID-19 Vaccine Receives Full FDA Approval

Prescribing information includes warning about risks for myocarditis and pericarditis, particularly in men younger than 40 years

Drinking and Smoking After First Trimester May Up Late Stillbirth

No significantly increased risk observed for pregnancies prenatally exposed to drinking only or smoking only

Higher Flavonoid Intake May Lower Systolic Blood Pressure

Higher consumption of berries, red wine linked to lower SBP; association partly explained by microbial factors

No Permanent Lung Damage Observed After COVID-19 Recovery

No difference seen between lung parenchyma of COVID-19 survivors and controls in specimens from unrelated elective lung resections

Most Parents Plan to Send Children to In-Person Learning, Despite COVID-19

Survey revealed racial gap between parents' preferences and safety concerns

Among Persons With HIV, More Finish Short-Course TB Prophylaxis

Treatment completion 90.4 percent for three months of rifapentine-isoniazid versus 50.5 percent for six months of isoniazid

Israeli Study Shows Pfizer Booster Gives Seniors Big Rise in Immunity

Israel approved booster shots for people aged 60 years and older late last month; the government lowered the age of eligibility to 40 years last week

Pentagon to Make COVID-19 Vaccination Mandatory for Military

Officials are preparing to issue guidance to require vaccination, although no exact timeline has been given

Stop Using Ivermectin Veterinary Drug to Treat COVID-19, FDA Urges

No form of ivermectin has been approved to treat or prevent COVID-19, the agency emphasized

Half of Youth E-Cigarette Users Intend to Quit

Vaping cessation behaviors tied to tobacco co-use, vaping device, harm perceptions, and reasons for vaping

Screening Mammograms Plummeted During COVID-19 Pandemic

Drop in breast cancer screenings at one safety-net hospital raises concerns for worsening of preexisting health disparities

Milrinone, Dobutamine Similarly Effective for Cardiogenic Shock

Incidence of adverse clinical outcomes, including in-hospital death, high in both groups in pragmatic randomized clinical trial

Opioid Tapering Tied to Higher Risk for Overdose, Mental Health Crisis

Rates of overdose, mental health crises increased after dose tapering among patients prescribed stable, long-term, higher-dose opioid therapy

Higher Maternal Lipid Profile Tied to Congenital Heart Disease in Offspring

Doubled risk seen for high triglyceride, total/high-density lipoprotein, and apolipoprotein-A1

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

mRNA COVID-19 Vaccine Effectiveness Lower During Delta Strain Era

Adjusted effectiveness 53.1 percent against infection in nursing home residents during period when delta strain was predominant

Regional Stroke Triage by EMS Ups Endovascular Therapy Rate

Implementation of a prehospital transport policy tied to sharp and sustained change in endovascular therapy rates

mRNA Vaccine Effective Against Hospitalization Over 24-Week Period

Pfizer-BioNTech and Moderna vaccines effective against COVID-19-associated hospitalizations among adults

Long-Haul COVID-19 May Affect Two of Three With Mild, Moderate Disease

Authors say these estimates are similar to estimates in hospitalized patients

1.69 Million Deaths Attributed to Extreme Temperatures in 2019

Acute heat and cold exposures increase mortality risk for multiple causes of death; cold-attributable exceeds heat-attributable mortality

COVID-19 Immune Response Appears Strong in Cancer Patients

Vast majority show seropositivity four months after the second COVID-19 vaccine dose

Workplace Mistreatment Reported Frequently by Emergency Medicine Residents

Patients and/or patients' families are a frequent source of mistreatment; 2.5 percent of residents report suicidal thoughts

Risk for Myocarditis in Young Who Get Moderna Shots May Be Greater Than Thought

However, health officials emphasize that COVID-19 puts someone at much greater risk for heart inflammation than getting the vaccine does

Significant Gender Pay Gap Persists in Anesthesiology

Women anesthesiologists receive an average of $32,600 less per year; gap exists even when adjusting for differences in age, hours worked, geographic practice region

Decision on J&J COVID-19 Vaccine Booster Doses Could Take Weeks

Federal health officials are waiting on results from a government-backed clinical trial and from studies by Johnson & Johnson

Higher Maternal Prenatal BMI May Harm Child Cognition

5-unit increase in maternal late-pregnancy BMI linked to lower WASI performance IQ, NeuroTrax scores at age 6.5 years

Previous Tx in Metastatic Melanoma May Cut Response to ACT TIL

Prior therapy linked to lower objective response rate to adoptive cell transfer with tumor-infiltrating lymphocytes compared with no prior therapy

COVID-19 Vaccine Effectiveness Down Against New Infections in New York

Recent decline in vaccine effectiveness against new COVID-19 cases coincided with increasing circulation of delta variant

Sedentary Time Ups Stroke Risk for Younger Adults With Low Activity

Stroke risk increased with sedentary time of at least eight hours a day for those younger than 60 years with low physical activity

FDA: Stop Using Eco-Med Ultrasound Gels, Lotions

Health care providers, facilities should stop using and discard all ultrasound gels and lotions due to risk for bacterial contamination

Cognitively Stimulating Jobs May Lower Risk for Dementia

Higher cognitive stimulation at work linked to lower levels of proteins that inhibit CNS axonogenesis and synaptogenesis

Biden Puts Pressure on Nursing Homes to Vaccinate Staff Against COVID-19

New mandate, which will come in the form of a regulation to be issued by CMS, could happen next month

Oral Atogepant Effective for Reducing Number of Migraine Days

Results also favored atogepant over placebo for most secondary end points; constipation, nausea most common adverse events

Pesticide to Be Banned Over Ties to Neurological Damage in Children

New rule to block the use of chlorpyrifos on food will take effect in six months

Almost 140,000 COVID-19 Deaths Averted With Vaccinations

Vaccination-associated reduction in deaths translated to statistical life benefit ranging from $625 billion to $1.4 trillion

Family Behind Oxycontin Denies Any Responsibility for Opioid Crisis

When asked if he carries any responsibility for the opioid crisis in the United States, Richard Sackler firmly replied: 'No'

High-Intensity Interval Training Beneficial in Prostate Cancer

PSA level, velocity, and prostate cancer cell growth reduced with HIIT in men with localized prostate cancer under active surveillance

Maternal Diabetes Ups Offspring Risk for High Refractive Error

Offspring of mothers with diabetic complications have more pronounced increased risks than those of mothers with diabetes without complications

AHA Statement Addresses Impact of Childhood OSA on Heart Health

Main risk factor for OSA in childhood is obesity; families and health care professionals should be counseled regarding this link

Adjuvant Pembrolizumab Beneficial in Renal Cell Carcinoma

Rate of disease-free survival at 24 months higher with pembrolizumab versus placebo following nephrectomy

Dexamethasone Studied for Treatment of Heavy Menstrual Bleeding

Results of dose-finding study suggest dexamethasone is safe for use at a dosage of 1.8 mg daily for five days per menstrual cycle

Recall of Philips Breathing Machines Affects Millions of Americans

About 2 million of the recalled machines were in use in the United States

TSA Extends Mask Mandate for U.S. Travelers to January

Mandate was set to expire on Sept. 13; travel industry supports the extension

Childhood Parental Smoking Linked to Adult-Onset RA

Association seen among women even after controlling for adult personal smoking, with strongest association among ever smokers

Cannabis Use Lower in Cancer Survivors Than General Population

Factors associated with use or nonuse found to be similar between the groups

Tree Nut Whole Extract Sensitization Common in Adulthood

Whole extract sensitization is usually asymptomatic; storage protein sensitization is more reliable indicator of tree nut allergy symptoms

Adalimumab Efficacious Adjunct to Surgery for Hidradenitis Suppurativa

Risk for postoperative wound infection, complications, hemorrhage no greater with adalimumab versus placebo in hidradenitis suppurativa

Early-Onset CRC Biologically Similar to Average-Onset CRC

No significant differences seen at gene or pathway level according to age; chemotherapy response, survival equivalent by age groups

Blacks Remain Underrepresented in U.S. Medical School Faculty

No medical specialty has Black faculty representation in proportion to current U.S. population estimates

COVID-19 Vaccines Well Tolerated Among Reproductive-Aged Women

Findings seen in large study of women who were pregnant, lactating, or planning pregnancy

Fifteen Headache-Day Threshold Does Not Capture Migraine Burden

Findings raise questions about the current headache frequency used for classification of migraine headaches

Household SARS-CoV-2 Transmission Higher With Younger Children

Odds of secondary transmission higher for children age 0 to 3 years and 4 to 8 years versus 14 to 17 years

Antibiotic Dispensing Decreased After COVID-19 Restrictions

36 percent reduction seen in antibiotic dispensing after COVID-19 restrictions; large reduction found in antibiotics for RTIs

Management Strategies Compared for Pregnancy of Unknown Location

Active management may be more effective than expectant management in resolving early nonviable pregnancy of unknown location

COVID-19 Booster Shots for All Americans, Starting Sept. 20

Plan calls for Americans to get a booster shot eight months after their second dose

Child Injuries, Deaths Spur Recall of 10 Million Magnet Balls, Cubes

Products sold online at Neoballs.com and ZenMagnets.com beginning in January 2009

Avanti Expands Recall of Frozen Shrimp for Possible Salmonella Contamination

There have been nine reports of Salmonella-related illness associated with the recalled products

U.S. National Park Service Issues Mask Mandate

Along with all NPS buildings and public transportation systems, masks will be required in outdoor spaces where social distancing is not possible

2011 to 2019 Saw Rates of GDM Increase Across Race, Ethnicity

Highest gestational diabetes rates were seen in Asian/Indian participants; Puerto Ricans had highest rate among Hispanic/Latinas

Racial, Ethnic Differences in U.S. Health Metrics Persist

Racial and ethnic differences in health status, care access improved in some subgroups; mainly persisted in U.S. adults from 1999 to 2018

Minorities, Women Underrepresented in Pancreatic Cancer Trials

84.7 percent of patients in clinical trials were White and 54.8 percent were men; underrepresentation seen in trials of nearly all phases

Toe, Foot Amputations Increasing in Minorities, Rural Residents With Diabetes

Rates of minor lower-extremity amputations rising among Asian/Pacific Islanders

Lyme Disease Tied to Higher Risk for Psychiatric Conditions, Suicide

Risk particularly heightened in the six months following diagnosis

Rule Change Led to Short-Term Drop in Nonmedical Exemptions

32 percent decrease in NMEs in Michigan seen immediately after rule change, but rebound seen in subsequent years

Model Predicts False-Positives in Breast Cancer MRI Screen

Full prediction model could prevent 45.5 percent of false-positive recalls, 21.3 percent of benign biopsies for those with extremely dense breasts

U.S. to Recommend Booster Shots for Most Americans

Officials could announce the decision as early as this week, with third shots becoming available to those most vulnerable as early as mid-September

Widespread Pain Tied to Dementia, Alzheimer Disease, Stroke

After adjustment for multiple variables, widespread pain appeared to increase subsequent risk

Global Numbers of Suicide Deaths on the Rise

From 1990 to 2019, decrease in age-specific suicide rates offset by population growth and aging to increase numbers of suicide deaths

Flu Vaccine May Protect Against Adverse Events After SARS-CoV-2

Individuals with flu vaccination have lower risks for sepsis, stroke, and DVT, emergency department and ICU admissions

Doctors More Likely to Test for Conditions Recently Diagnosed in Other Patients

When seeing patients with shortness of breath, testing for pulmonary embolism increases for 10 days after diagnosing a patient with the condition

Age, Ethnicity Tied to Less Follow-Up Care in Childhood Cancer Survivors

Authors say improving long-term follow-up is needed to better manage survivors' health in adulthood

Canada to Mandate COVID-19 Vaccines for All Plane, Train Travelers

More than 71 percent of eligible Canadians are fully vaccinated, and 82 percent have had at least their first shot

Biden Administration to Greatly Expand Food Stamp Program

Enrollment in SNAP has more than doubled since the early 2000s, and about 43 percent of beneficiaries are children

Almost Half of Pediatric Opioid Prescriptions Considered High-Risk

61.4 percent of the prescriptions written by dentists, surgeons; high-volume prescribers wrote more than half of prescriptions

Body Dissatisfaction in Youth Not Tied to Socioeconomic Status

Findings seen in longitudinal study of U.S. teens of diverse backgrounds recruited from schools in the Minneapolis-St. Paul, Minnesota area

Vitamin K Inversely Linked to Risk for Atherosclerotic CVD

Participants with diets high in vitamin K1 and vitamin K2 have reduced risk for atherosclerotic CVD in adjusted analyses

Exercise Linked to Decrease in Deaths, Regardless of Air Pollution

In each PM2.5 stratum, moderate and high levels of exercise were associated with a reduced risk for death versus inactivity

Preop Isolation May Up Risk for Postop Pulmonary Complications

Pandemic-related preoperative isolation linked to higher rates of postoperative pulmonary complications following elective surgery

Greater Height Loss in Middle Age Tied to Higher Risk for Death in Women

Findings driven by cause-specific mortality, including cardiovascular-related mortality

COVID-19 Outcomes in Critically Ill No Better With Full-Dose Heparin

For patients hospitalized with COVID-19 who are not critically ill, therapeutic-dose anticoagulation is beneficial

Text Reminders Boost COVID-19 Vaccine Appointments

Messages that stress the accessibility of the vaccine and include 'ownership' language most effective

Toxic Dust Exposure Tied to Liver Disease in WTC Responders

Earlier arrival time at World Trade Center associated with decreased liver attenuation on computed tomography

Acupuncture Alleviates Chronic Prostatitis, Pelvic Pain in Men

At 24-week follow-up, more patients experienced symptomatic relief with eight weeks of acupuncture sessions versus sham treatments

Dexamethasone Underused for Adults Hospitalized With COVID-19

Dexamethasone and remdesivir use have gradually increased during the pandemic; hydroxychloroquine use peaked in March 2020

Exposure to Prenatal Antipsychotics Seems Safe

No increased risk seen for ADHD, ASD, small for gestational age with prenatal antipsychotics exposure

High BMI Variability, Adverse Outcomes Linked in Predialysis CKD

Variabilities in metabolic syndrome components linked to prognosis, with worse prognosis for more components with high variability

Brain-Training App Aids Cognitive Function After Brain Injury

Cognitive improvement seen in vets using self-administered program remotely for 12 weeks, with results sustained for an additional 12 weeks

Handling of Secondary Genetic Findings in Research Examined

When given more information, almost half of research participants who initially refused opted to accept secondary genetic findings

ASTRO Issues Guideline on RT for Soft Tissue Sarcoma in Adults

Multidisciplinary evaluation recommended for all cases of STS; when indicated, preoperative RT recommended over postoperative RT

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Health Coaching + Change in Early-Life Care Benefits Babies, Moms

Findings show reduced infant overweight and increased receipt of maternal postpartum care among low-income dyads

Wildfires May Amplify Effect of PM₂.₅ Exposure on COVID-19 Dynamics

Increases in COVID-19 cases and deaths seen in 28 days following wildfire-linked increases in PM2.5

Xywav Gets FDA Approval to Treat Rare Sleep Disorder

First drug to be approved by the agency for idiopathic hypersomnia

COVID-19 Outbreak Reported on Carnival Cruise Ship

The 27 cases on the Carnival Vista reported by the Belize Tourism Board include 26 crew and one guest

Largest U.S. Teachers’ Union Supports Mandatory COVID-19 Vaccination

Union says nearly 90 percent of its members report being fully vaccinated

Third Dose of mRNA-1273 Boosts Immunity in Transplant Recipients

More patients receiving mRNA-1273 booster have serologic response with anti-receptor-binding domain antibody level of at least 100 U/mL

FDA OKs Third COVID-19 Shot for Vulnerable Americans

Authorization includes people who have had solid organ transplants and those whose immune systems are equally compromised

NSAID Eye Drops May Suffice for Cataract Surgery Prophylaxis

Initiation of prophylactic treatment three days before surgery is not superior to initiation on day of surgery

Cannabidiol Relieves Burnout for Health Care Workers During Pandemic

Emotional exhaustion reduced, but five participants in treatment group experienced serious adverse events

Uninsurance Rates Up for Low-Income Adults During Pandemic

Medicaid expansion linked to protection against the increase in uninsurance among Black, Latinx individuals

Health Care Visits for Sunburn Are Rare

Most sunburn encounters occur in the outpatient setting and are treated by a dermatologist or family medicine provider

1,173 Cases of Domestic Arboviral Disease Reported in 2019 in United States

83 percent of these were West Nile virus disease cases, of which 65 percent were classified as neuroinvasive disease

Physical Activity Linked to Lower Mortality in Stroke Survivors

Dose-response relationship seen; most of the risk reduction occurred between 0 and 20 metabolic equivalent hours/week

All HHS Health Care Workers Must Now Get COVID-19 Vaccines

Order will affect more than 25,000 clinicians, researchers, contractors, trainees, and volunteers

COVID-19 Vaccines Now Mandatory for California Teachers, School Staff

Announcement comes as growing number of public and private employers nationwide implement vaccination mandates

Cabotegravir Bests TDF-FTC for HIV Prevention in Those at Risk

Long-acting injectable cabotegravir superior for preventing HIV infection in men who have sex with men, transgender women

AAP: Consider Palivizumab for Atypical Interseasonal RSV

AAP strongly supports consideration of palivizumab for patients who would be candidates per current eligibility recommendations

mRNA-1273 SARS-CoV-2 Vaccine Seems Safe for Adolescents

Interim analysis shows immune response in adolescents aged 12 to 17 years noninferior to that in young adults aged 18 to 25 years

Features of Vaccine-Induced Thrombotic Syndrome Studied

No individual risk factors identified for VITT, but increased mortality seen for those with cerebral venous sinus thrombosis, low platelets

DPP-4i Use May Protect in Alzheimer Dementia With Diabetes

Low amyloid burden and favorable cognitive outcomes seen with DPP-4i use in Alzheimer disease-related cognitive impairment with diabetes

Some Newer Antiseizure Meds May Not Increase Suicide Risk

Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited

Most Preprocedural Urinalyses Represent Low-Value Care

Between six and 28 percent of preprocedural urinalyses that were not indicated were followed by an antibiotic prescription

FDA to Approve COVID-19 Booster Shots for Vulnerable Americans

About 3 percent of Americans have weakened immune systems

Phone App Captures Measures of Functional Impairment in MS

Associations between almost all tests with domain-specific standard clinical disability measures were significant

Breaded, Raw Chicken Recalled in Multistate Salmonella Outbreak

CDC, FSIS investigating 28 cases of Salmonella illness in eight states

Americans Have High Trust in Health Care Providers: Poll

Trust in health care providers could be an important factor in efforts to boost COVID-19 vaccination rates

New, Tighter COVID-19 Rules Coming for Oregon

New rules in Oregon come as battles over masks rage in some other states

U.S. Sees Big Spike in COVID-19 Vaccinations

Daily number rose from 226,209 on July 5 to about 441,198 on Aug. 5

Experts Demand That Biden Do More to Distribute COVID-19 Vaccines Globally

More than 50 organizations have cosigned letter sent to senior White House officials

1990 to 2017 Saw Increase in Global Incidence of Mesothelioma

Mesothelioma incident cases and deaths associated with mesothelioma decreased after 20 years of complete ban on asbestos

Subjective Social Status, Heart Health Linked in Hispanics/Latinos

Increase in perceived social status linked to increased likelihood of ideal levels of BMI, exercise, fasting blood glucose

Cutaneous Beta-HPV May Up Risk for Cutaneous Squamous Cell Carcinoma

Beta-HPV detected in skin swabs may predict cuSCC risk, but no link seen for serologic evidence of past beta-HPV infection

Risk for Autism Spectrum Disorder Up With Preterm, Early-Term Birth

Risk increased among boys and girls; associations only slightly attenuated after controlling for shared familial factors

Fewer Cancers Might Be Missed With Full-Body Skin Examinations

Authors recommend that dermatologists perform a total-body skin examination even when a patient is referred for a suspicious lesion

25 Weeks May Be Cutoff for Severe Neurological Outcomes in Preemies

Preterm delivery before 25 weeks of gestation may be a critical threshold for increased risk for long-term neurological complications

Racial/Ethnic Disparities Seen in Anticoagulant Initiation for A-Fib

Disparities seen among VA patients both for initiating any anticoagulant therapy and for initiating direct-acting oral anticoagulant use

Targeted COVID-19 Vaccine Reminders Boost Uptake

Behaviorally informed messages were sent to health care workers who initially delayed receiving the COVID-19 vaccine

Prevalence of Obesity, Overweight High in Coronary Heart Disease

Overall, 19.5 percent of obese patients lost ≥5 percent of weight by six to 24 months after a CHD-related hospitalization

Low Vitamin D Levels Tied to Higher Risk for COVID-19 Infection

Risk for COVID-19 infection greater among U.S. Black women with serum levels of vitamin D lower than 20 ng/mL

COVID-19 Vaccine Safe, Recommended for Pregnant Women, CDC Says

Latest recommendation comes after new data showed no raised risk for miscarriage in mothers-to-be during first 20 weeks

Monthly COVID-19 Hospitalization Rates Peaked in December 2020

Peak reported in hospitalization, ICU admission, death, but decrease found in frequency of ICU admission, mechanical ventilation, vasopressor use

COVID-19 Vaccines Effectively Prevent Hospitalization for Seniors

Pfizer-BioNTech, Moderna, Janssen vaccines highly effective for preventing COVID-19-linked hospitalization

Consumption of Ultraprocessed Food Up Among Youth

Findings show that from 1999 to 2018, ultraprocessed food made up the majority of youths' total energy intake

USPSTF Recommends Screening for Gestational Diabetes at 24 Weeks

Screening for gestational diabetes at or after 24 weeks of gestation has moderate net benefit to improve maternal and fetal outcomes

Lung Cancer Screening Rates Mainly Unchanged During Pandemic

National LCS rates were unchanged between 2019 and 2020; significant declines seen in five states and increases recorded in 19 states

Increased Crowding Linked to COVID-19 Incidence in Prisons

COVID-19 transmission in the surrounding county consistently associated with COVID-19 incidence in prisons

Enzyme Replacement Therapy Approved for Late-Onset Pompe Disease

Patients taking Nexviazyme saw improvements in respiratory function and walking distance measures

U.S. Military Members Must Get COVID-19 Vaccine by Mid-September

Pentagon plan gives the FDA time to give final approval to the Pfizer vaccine, which is expected to come early next month

CDC: Fourth Case of Melioidosis Found in United States

Two of the four patients have died, the agency said Monday

Diagnosis of Inflammatory Arthritis Tied to Impaired Male Fertility

Men diagnosed at age 30 years or younger had a significantly lower mean number of children than those diagnosed at age 31 to 40, 41 years or older

Physical Function Worse for Migraine, Overlapping Pain

Worse pain-related physical function, psychosocial functioning, increased health care utilization reported for chronic migraine with overlapping pain

Barriers Persist for Enrolling Women in Cardiology Clinical Trials

Eight barriers discussed include differential care, ageism, logistical barriers, lack of diversity in clinical trial leadership