2000 to 2020 Saw Increase in Drug Overdose Death Rates in Seniors

For men aged 65 to 74 and 75 years or older, drug overdose death rates were higher for non-Hispanic Black men

Timing of Puberty Linked to Risk for Self-Harm in Adolescence

Earlier puberty associated with higher risk for self-harm at 16 years of age

Cytomegalovirus Linked to Faster Progression of Cystic Fibrosis

Faster progression to end-stage lung disease observed among patients with CMV IgG positivity

ACS: Surgery May Benefit Men With Stage IV Breast Cancer

Patients receiving systemic therapy, surgery, and radiation have survival advantage over systemic therapy alone

11.2 Percent of Pediatric Cancer Patients Positive for SARS-CoV-2

Rate of positivity 29.3 percent among screen- or symptom-positive patients; 2.5 percent in asymptomatic patients

Vision, Balance Issues Common With Pediatric Concussions

Visiovestibular clinical assessments often not performed in the emergency department setting

Bariatric Surgery Cuts Hepatic Steatosis in Obesity and T2DM

Similar decline in liver fat fraction seen for sleeve gastrectomy, Roux-en-Y gastric bypass from surgery to one-year follow-up

Many Patients Receive Guideline-Nonconcordant Care for Low Back Pain

One-third of patients received opioids, more than half of whom had not received prescription NSAIDs, PT

AUA: Marijuana Tied to Increased Risk for LUTS Medications in BPH

Marijuana use also linked to worse overall semen parameters due to induction of oxidative stress

Ticagrelor DAPT Linked to Lower Risk for Vein Graft Failure in CABG

But addition of ticagrelor linked to increased risk for BARC type 2, 3, or 5 bleeding events versus aspirin

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Cognitive Remediation Benefits Patients With Schizophrenia

Benefits include cognitive and functional outcomes even for severely affected patients

Prescriptions Rise for Veterinary Drug for COVID-19 Patients

Increase in demand for ivermectin has been accompanied by a fivefold increase in calls to poison control centers

Hemodialysis Facility Practices Linked to Patient Outcomes

Protocol that specifies how often to assess dry weight tied to lower all-cause, CVD mortality

Fear of COVID-19 Keeping Adults From Emergency Care

About 80 percent of poll respondents concerned about contracting COVID-19 from another patient, visitor

IDSA: Long-Term Follow-Up Reported for Early Initiation of ART in HIV

Excess risk for AIDS, serious non-AIDS conditions, death for those deferring treatment reduced soon after initiation of ART

Low Glucose Levels at Hospital Discharge Tied to Poor Outcomes

Patients with diabetes and hypoglycemia have higher readmission rate, postdischarge mortality

Once-Weekly Insulin Icodec Promising for Type 2 Diabetes

Icodec results in greater increase in time-in-range versus once-daily insulin glargine U100 in two phase 2 randomized, open-label trials

U.S. Adults Support Net-Risk Pediatric Research

Most support pediatric research posing minimal risk and research posing greater risk if it has high social value

Adjuvant Nivolumab Beneficial in Esophageal, GE Junction Cancer

Disease-free survival significantly longer in patients with resected esophageal, gastroesophageal junction cancer

Exercise Intervention During Chemotherapy Beneficial

Intervention during chemo linked to lower decreases in VO2peak, health-related QoL, muscle strength immediately postchemotherapy

Statins Tied to Lower In-Hospital COVID-19 Mortality Risk

For adults hospitalized in Spain with COVID-19, treatment with statins associated with lower COVID-19-related mortality

MMR Not Linked to Autism in Danish Cohort Study

No increased risk observed after MMR in those with sibling autism history, autism risk factors

August 2020 Briefing – Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for August 2020. This roundup includes the latest...

New Drug For Vaginal Yeast Infections Approved by FDA

Brexafemme offers an alternative to Diflucan but at greater cost

FDA Panel to Weigh Improved Booster Shots From Moderna, Pfizer

Both Pfizer and Moderna have been testing updated booster shots that target the omicron variant

Smokers More Likely to Report Symptoms Suggestive of COVID-19

Current smokers have increased risk for reporting classic symptoms, more than five symptoms, more than 10 symptoms

Pembrolizumab Ups Survival in Advanced Triple-Negative Breast Cancer

Overall survival longer with addition of pembrolizumab to chemo in tumors expressing PD-L1 with combined positive score of 10 or more

USPSTF Presents New Approach to Sex, Gender in Recommendations

Task force will use inclusive approach to identify issues related to sex, gender in guideline development; will use gender-neutral language

Machine Learning Algorithms Can Classify Surgical Expertise in VR Simulation

Participants were classified by level of expertise with 90 percent accuracy, using six parameters

BNT162b2 Vaccine Effective Against Severe COVID-19 in Adolescents

Two doses highly effective against COVID-19-related hospitalization and critical illness for those aged 12 to 18 years

Adding a P2Y12 Inhibitor Does Not Improve Outcomes in COVID-19

Adding a P2Y12 inhibitor to a therapeutic dose of heparin does not improve outcomes among non-critically ill patients hospitalized for COVID-19

One in Five Adults May Have Avoided Health Care During the Pandemic

Finding among large survey of Dutch adults, including those with potentially urgent symptoms

USPSTF Urges CRC Screening for Adults Aged 50 to 75, 45 to 49

USPSTF concludes with moderate certainty that CRC screening has moderate net benefit for those aged 45 to 49 years

Performance of ESC 0/1-, 0/2-, 0/3-Hour Algorithms for AMI Compared

European Society of Cardiology 0/1-, 0/2-hour algorithms have higher sensitivities and negative predictive values than 0/3-hour algorithm

Survivors of Childhood Cancer More Likely to Be Undertreated for CVD

Increased health-related self-efficacy associated with significantly reduced likelihood of undertreatment

Terlipressin Bests Placebo in Type 1 Hepatorenal Syndrome

Terlipressin is more effective for reversal of HRS but is associated with more adverse events and death due to respiratory disorders

Abemaciclib Beneficial for HR+, HER2− Early Breast Cancer

Significant improvements seen in rates of invasive disease-free survival, distant recurrence-free survival

Some Newer Antiseizure Meds May Not Increase Suicide Risk

Current evidence does not support increased suicidality for certain newer antiseizure medications; class warning may not be merited

Most Children Experience Fluctuations in ADHD Symptoms

While nearly one in three will experience points of remission of ADHD symptoms, most experience recurrence over time and few outgrow it

Maternal H1N1 Flu Vaccination Not Linked to Autism in Offspring

Prenatal exposure not associated with diagnosis of autism spectrum disorder, autistic disorder

Survivors of Adolescent, Young Adult ALL May Suffer Late Effects

Estimated 10-year cumulative incidence high for subsequent endocrine disease, cardiac disease

May 2020 Briefing – Otolaryngology

Here are what the editors at HealthDay consider to be the most important developments in Otolaryngology for May 2020. This roundup includes the latest...

16 Illnesses, One Death Reported From Listeria in Deli Meat, Cheese

Many of the 16 who got sick are of Eastern European background or speak Russian and ate food from deli counters

Specific Postoperative Complications Increased for Patients With Obesity

Odds of infection, venous thromboembolism, renal complications increased for patients with overweight, obesity

January 2019 Briefing – Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for January 2019. This roundup includes the latest...

Combination Treatment Beneficial in Albuminuric CKD

7.4 year gain in event-free survival for 50-year-old patients with combo therapy with ACEi/ARB and SGLT2 inhibitors

Alcohol Brief Intervention Can Improve Health Outcomes in HTN

Adults with hypertension had modest but significant reduction in drinks at 12 months and in BP at 18 months

Ticagrelor, Prasugrel Compared in ACS Treated With PCI

Prespecified subgroup analysis of data from a randomized clinical trial suggest that a prasugrel-based strategy is preferable

Reviews Assess Tools to Identify, Diagnose, Treat Alzheimer Dementia

Many cognitive tests can differentiate clinical Alzheimer-type dementia from normal cognition

2010 to 2017 Saw >5,000 Travel-Linked Dengue Virus Cases in U.S.

Distribution of cases equal between men and women; patients had median age of 41 years

COVID-19 Suspected for Surge in Medical Visits at End of 2019

Excess seen for visits with cough in outpatient clinics, ED; hospitalizations with acute respiratory failure

Weaning Occurs Earlier for Infants With In-Hospital Formula Feeding

2.5-fold increased hazard of weaning found after adjustment for medical indicators of supplementation

Few Brains From Deceased Military Personnel Have Evidence of CTE

All brains with chronic traumatic encephalopathy were from decedents who had participated in contact sports

Genetic Testing Underused in Breast, Ovarian Cancer

Pathogenic variants ID'd in 7.8 percent of patients with breast cancer, 14.5 percent with ovarian cancer

Social Vulnerability Tied to Higher Assault-Related Firearm Death Rates for Youth

Despite burden among socially vulnerable youth, states with restrictive gun laws have lower rates of assault-related firearm deaths

Racial/Ethnic Disparity Seen for Stroke in Dialysis Patients With A-Fib

Rates of stroke higher for minority dialysis patients with a-fib partly due to lower anticoagulant use

Acalabrutinib Promising for Treatment of Severe COVID-19

Selective bruton tyrosine kinase inhibitor treatment may improve oxygenation, reduce inflammation

Recommendations Simplified for Pneumococcal Vaccination

ACIP recommends PCV20 alone or PCV15 in series with PPSV23 for all aged 65 years and older or younger adults at risk

Hydrocortisone Early After Septic Shock Onset May Aid Outcomes

Days alive and free from vasopressors greater for initiation within 24 hours versus >48 hours

Odds of Gabapentin Rx Down for Adults With LBP Receiving Spinal Manipulation

Reduced odds seen for receiving gabapentin prescription in adults receiving chiropractic spinal manipulative therapy

Regular, Short Breaks From Sitting Aid Cardiometabolic Markers

Breaks every 30 minutes for five minutes may be enough to improve glycemic responses

Mindful Music Listening Aids Cognitive Recovery After Stroke

Mindful music listening feasible, acceptable, may be effective after stroke

Targeted Intraoperative RT Is Effective Alternative to EBRT

TARGIT-IORT during lumpectomy noninferior to EBRT for local recurrence in women with early breast cancer

Men Who Have Sex With Men Acting to Prevent Monkeypox Transmission

MSM report reducing their number of sexual partners, one-time sexual encounters, sex with partners met on dating apps

Adverse Maternal Outcomes Up With Motor Vehicle Crashes in Pregnancy

Increased risks seen for placental abruption, prolonged uterine contractions, antepartum hemorrhage, cesarean delivery

Pfizer to Seek Approval in Fall for COVID-19 Vaccine Use in Children Aged 2...

Company also plans to apply to the FDA this month for full approval of the vaccine for use in people ages 16 to 85 years

TXA Seems Safe for Surgery in High-Risk Patients With IT Hip Fracture

No increased risk for mortality or thromboembolic complications seen with use of tranexamic acid among high-risk patients, entire cohort

Pediatricians’ Group Urges That All Infants Get New RSV Shot

The American Academy of Pediatrics recommendation applies to infants 19 months of age or younger

Methotrexate May Impair Immune Response to mRNA COVID-19 Vaccine

Poorer humoral, cellular immune responses seen in patients receiving methotrexate for immune-mediated inflammatory disease

Poverty-Stricken Adults More Likely to be Calcium-, Vitamin D-Deficient

Data suggest that nutrient deficiencies affect osteoporosis risk more for poverty-stricken men versus women

Complications Higher Than Expected for Invasive Lung Tests

Complication rates for invasive lung diagnostic procedures higher than those seen in clinical trials

10.8 Percent of Children Live in Households With Food Insecurity

Percentage of children living in food-insecure households in 2019 to 2020 varied by ethnicity, urbanicity, family structure

Total Joint Arthroplasty Linked to Reduced Risk for Falls

Risk for falls significantly reduced for patients undergoing total hip, knee arthroplasty for osteoarthritis

Review Examines Methods for Diagnosis of Elevated ICP in Critically Ill

Physical examination features not sensitive enough for diagnosis of elevated ICP in critically ill patients

Mild, No Symptoms for Most Children With SARS-CoV-2 Infection

Main radiologic findings are bronchial thickening, ground-glass opacities; also seen when asymptomatic

Major Insurers Offer $55 Million to Lower Generic Drug Costs

Nonprofit Civica Rx reached deal with Blue Cross Blue Shield and 18 of its member organizations

Feds Warn of Bedrails That Can Entrap; Three Deaths Reported

Warning applies to 10 models of bedrails made and sold by Mobility Transfer Systems

Methamphetamines, Opiates, Cocaine, Cannabis Up Risk for A-Fib

Methamphetamine, cocaine, opiate, and cannabis exposure each associated with increased incidence of AF

Decrease in PM2.5-Related U.S. Mortality From 2010 to 2017

During the same period, ozone-related mortality remained mainly unchanged

Neuropsychiatric Manifestations Seen in Monkeypox Patients

Headache, fatigue, and myalgia are reported frequently; serious complications, such as confusion, encephalitis, and seizure, are less common

Cognition Declines Tied to Hearing Loss Begin Early

Cognitive impairment starts as soon as hearing becomes imperfect, suggesting need for earlier testing, treatment

Uncontrolled Diabetes, Hypertension Rates High in CKD Patients

Findings also revealed low use of statins among patients with chronic kidney disease

February 2019 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for February 2019. This roundup includes the...

Furniture, TV Tip-Over Injuries Send Many Young Children to ED

Authors urge a mandatory safety standard for manufacturers and for families to anchor furniture to avoid head/neck injuries

No Sign of Vertical Transmission of COVID-19 Found in Late Pregnancy

Varied symptoms identified in nine pregnant women with 2019 novel coronavirus disease

Racial/Ethnic, Educational Barriers ID’d for DBT Screening Access

Use of digital breast tomosynthesis lower for Black versus White women, those with lower educational level, in lowest income quartile

Gestational Diabetes May Increase Risk for Fetal Hypoxia

Hypoxia-related ZigZag pattern, late decelerations of FHR on intrapartal CTG and increased risk of fetal asphyxia seen in GDM pregnancies

Stay-at-Home Orders Challenging Obese Patients

Survey respondents report difficulty in achieving weight loss goals, deteriorating mental health

Permanent Hair Dye Not Linked to Cancer Risk, Mortality

Risk increased slightly for basal cell carcinomas; positive link found for some breast cancers, ovarian cancer

Moderna Vaccine Top for Protection Against COVID-19 Hospitalization

Vaccine effectiveness higher for Moderna than Pfizer-BioNTech vaccine; both mRNA vaccines have higher VE than Janssen

Acetaminophen Exposure in Utero Tied to Child Neurobehavioral Problems

Problems with sleep, attention seen at age 3 years in children exposed to acetaminophen in utero

COVID-19 Case Fatality Rate High in Long-Term Dialysis Patients

Racial, sociodemographic, and dialysis-related factors predict COVID-19 infection risk among long-term dialysis patients

Pandemic Disrupting Health Care for 55 Percent of Older Adults

One in five older adults reported trying telemedicine; 49 percent find it comparable to an in-person visit

Firearm Use Up in Female Nurse Suicides in the U.S.

Female nurses used firearms in suicides less often than other women from 2003 to 2013, but firearm use increased from 2014 to 2017

Drop in Firearm Deaths Linked to More Restrictive Gun Policies

Restrictive gun policy has 0.98 probability of being associated with decrease in firearm-related deaths

Signs/Symptoms May ID COVID-19 Even With Negative RT-PCR

Patients who repeatedly tested negative but had signs/symptoms of COVID-19 had similar seroprevalence as RT-PCR-confirmed cases

Most Women Face 6 to 22 Percent Risk of Breast Cancer Metastases

Risk varies by age at diagnosis, decade of diagnosis, and type of breast cancer

February 2019 Briefing – Allergy

Here are what the editors at HealthDay consider to be the most important developments in Allergy for February 2019. This roundup includes the latest...

Health Coaches Improve Inhaler Use in COPD Patients

Significant improvements in inhaler adherence, technique seen for low-income patients

42.4 Percent of U.S. Teens Have Received at Least One COVID-19 Shot

Vaccination coverages vary by state, with rates of one dose or more ranging from from 20.2 percent in Mississippi to 70.1 percent in Vermont

Good Outcomes Seen With Primary Hip Arthroscopy for Borderline Hip Dysplasia

Overall survivorship of 82.2 percent seen at minimum follow-up of 10 years; significant improvement seen in all PROMs

Burden of Obesity-Associated Cancers Shifted to Younger Age Groups

Large study shows particular increase in the 50- to 64-year-old age group from 2000 to 2016

AI Assistance May Improve Accuracy of Breast Cancer Screening

Sensitivity increased for subgroups with small lesion sizes, invasive carcinomas

E-Cigarette Aerosol Exposure Tied to Asthma Symptoms

Findings seen among youth reporting asthma diagnosis, secondhand exposure to e-cigarette aerosols

Reinforced Learning Model Can Improve Sensitivity of Skin Cancer Diagnosis

Correct diagnoses made by dermatologists increased with reinforcement learning, incorporating human preferences into AI model

Experts Weigh in on Pace of Reopening, Preventive Measures

Marjorie Jenkins, M.D., and Thomas Giordano, M.D., talk with HD Live! about waning social distancing measures, rising infection rates in the youth population

Peripheral Nerve Stimulation May Cut Pain After Orthopedic Surgery

Pain scores, opioid consumption reduced in first postoperative week with percutaneous peripheral nerve stimulation versus sham treatment

Systemic Hormone Therapy During Menopause May Up Risk for Depression

Initiating systemic hormone therapy before age 50 years linked to increased risk for depression

Florida Bans Most Abortions After Six Weeks

New law will impact women in the state, as well as those in the region where many have traveled to Florida to access abortions

Melanoma Presentation, Mortality Varies by Race

Black patients face higher mortality with melanoma independent of insurance status and severity at diagnosis

Four Million New Peds Asthma Cases Attributed to NO2 Annually

Burden of new pediatric asthma cases accounts for 13 percent of global incidence

Vestibular Dysfunction May Be Modifiable Risk Factor for Cognitive Decline

Findings seen in study of patients with Meniere disease

Phthalate Exposure May Increase Diabetes Risk in Women

Increased incidence of diabetes seen with exposure to certain phthalates for White, but not Black or Asian, women

ASH Issues Guidance for Preventing, Treating VTE in Cancer

Use of thromboprophylaxis not recommended for ambulatory patients at low risk for VTE who are receiving chemotherapy

Trainee Demographics Tied to Passage of U.S. Surgical Boards

White and single residents more likely to pass the American Board of Surgery examinations

Antibiotic Exposure Positively Linked to IBD Development

Positive dose-response seen for all aged 10 years and older, with greatest risks for those aged 40 to 60 years and 60 years and older

December 2019 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for December 2019. This roundup includes the...

March 2019 Briefing – Psychiatry

Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for March 2019. This roundup includes the latest...

In California Study, Many Veterans at Risk of Suicide Have Unlocked Gun at Home

Suicide by firearm is the number one cause of suicide death among veterans

ASTRO Issues Recs for Radiation Tx of Basal, Squamous Cell Carcinoma

RT recommended as primary treatment for BCC, cSCC patients who are not surgical candidates

Many With Relapsed/Refractory Lymphoma in Pregnancy Delay Treatment

Five of 23 women studied received intentional antenatal therapy; no malformations or genetic diseases observed

AAN: Teriflunomide Reduces Clinical Events in Radiologically Isolated Syndrome

Significant reduction seen in clinical events with teriflunomide; nonsignificant reduction noted in Gd+ lesions, new or enlarging T2 lesions

Virtual, Hybrid Format Feasible for Cardiac Rehabilitation

Improvements in functional capacity similar to in-person cardiac rehabilitation

Treatment Rates for Major Depressive Disorder Low Worldwide

Even bigger gaps in care seen for people living in low-income and lower middle-income countries

Potentially Tainted Marijuana Sold in Colorado

To date, no reports of health problems associated with the affected marijuana have been received

Suicide, Homicide Rates Up Among Youth Aged 10 to 24

Suicide rates increased from 2007 to 2017, while homicide rates increased from 2014 to 2017

Judge Overturns Arkansas Law Banning Gender Transition Care for Minors

Judge contends law discriminates against transgender people and violates the constitutional rights of doctors

Physician Burnout Rate Increased From 2014 to 2017

Early-career physicians most susceptible to burnout; late-career physicians less vulnerable

Suicidal Behaviors, Deaths Lower for Childhood Cancer Survivors

But prevalence of suicidal ideation similar for childhood cancer survivors, general population

Stepped Tx for Alcohol Use Disorder Studied in HIV Patients

Gradually increasing intensity of treatment reduces alcohol intake and improves HIV status

Adding Maraviroc to c-ART No Better in Advanced HIV

Incidence of severe morbidity similar for addition of maraviroc versus placebo to standard c-ART

Flu Activity Low in Southern Hemisphere in June to August 2020

Little flu circulation anticipated in Northern Hemisphere flu season with community mitigation measures

2019 to 2022 Saw Increase in Mental Health Service Use, Spending

Telehealth visits increased more than 10-fold during acute phase of pandemic and remained high in postacute phase

Portable Low-Field MRI Allows Brain Imaging in ICU Patients

Feasibility of bedside brain MRI demonstrated in 50 patients admitted to neuroscience or COVID-19 ICUs

Odds of Severe, Critical COVID-19 Up With Vitamin D Deficiency

Patients with severe or critical disease more often had preinfection vitamin D deficiency than those with mild-to-moderate disease

FDA Testing Levels of Carcinogen in Diabetes Drug Metformin

No metformin recalls affect U.S. market at the moment

Many Psychiatric Patients Are Getting Risky Drug Gabapentin ‘Off-Label’

By Amy Norton HealthDay Reporter MONDAY, Nov. 22, 2021 (HealthDay News) -- Most prescriptions for the medication gabapentin are for unapproved uses -- and many...

FDA: Tattoo Inks Recalled Due to Bacterial Contamination

Symptoms of tattoo ink-associated infections include rashes, lesions in areas where ink has been applied

RSV in First Year of Life Tied to Risk for Childhood Asthma

Authors say association is age- and severity-dependent

Long-Term Diastolic Dysfunction Seen After Early Preeclampsia

Cardiac dysfunction associated with previous preeclampsia is quantifiable and persistent

Hospitalization Rates Up During Omicron BA.2 Predominance

Hospitalization rates 3.4 times as high for unvaccinated adults compared with vaccinated adults

Global Coronavirus Outbreaks Stoking Fears of Pandemic

Mild nature of most cases of COVID-19 making the virus difficult to identify and contain

Public Health Interventions Could Cut Global Burden of Hepatitis C

Package of prevention, screening, treatments could avert 15.1 million new infections versus 2015

Lower Mortality Seen With Hemodiafiltration for Kidney Failure

Risk for death from any cause reduced with hemodiafiltration versus hemodialysis among patients with kidney failure

January 2020 Briefing – Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for January 2020. This roundup includes the latest...

New Ebola Drugs Highly Effective, Might Shorten Outbreak in Africa

The treatments, REGN-EB3 and mAb-114, are both monoclonal antibodies

Cardiovascular AEs Common With Carfilzomib in Multiple Myeloma

Patients with relapsed multiple myeloma experiencing CVAEs had inferior survival

Trastuzumab Tied to Higher Long-Term Risk for Heart Failure

Increased risk for heart failure seen in breast cancer survivors given trastuzumab rather than chemo alone

Myorelaxants, NSAIDs, NSAID-Acetaminophen Combo Ease Lower Back Pain

No improvement seen in lower back pain with acetaminophen alone or placebo across trials

Vascular Deaths Down for Diabetes Patients in the U.K.

Cancer is now the leading contributor to death among individuals with diabetes living in England

No Evidence Found for SARS-CoV-2 Vertical Transmission to Fetus

No maternal-fetal transmission of SARS-CoV-2 seen to date in pregnant women with COVID-19

Fatty Tissue Transfer Benefits Arthritic Finger Joints

Minimally invasive procedure associated with significant improvements of osteoarthritis symptoms

Poverty Ups Risk for Amputation After Knee Replacement

No racial or sex disparities seen for risk for amputation after periprosthetic joint infections

Adverse Childhood Experiences Led to Poorer Mental Health During Pandemic

Teens reporting four or more ACEs during pandemic had prevalence of poor current mental health four times higher than those without ACEs

New Coordinator Appointed for U.S. Global Response to COVID-19 Pandemic

Gayle Smith's duties will include harnessing U.S. knowledge and resources to increase COVID-19 vaccine production and distribution worldwide

Minerals Not Linked to Multiple Sclerosis Risk in Women

Associations null when women with highest versus lowest intake in quintiles, deciles compared

TKA Complications Increased for Sickle Cell Disease Patients

Patients with sickle cell disease have longer length of stay, incur greater health care costs, have increased need for step-down health care facilities

Short-Term Mortality Link Identified for Increased Ozone Exposure

Exposure to ozone greater than maximum background levels linked to short-term excess mortality of 0.26 percent

Europe Surpasses 1 Million COVID-19 Deaths

WHO wants to emphasize the need for Europe to maintain social distancing and speed up vaccinations

Federal Court Orders EPA to Reexamine Whether Roundup Causes Cancer

In its ruling, court challenged Trump-era finding that glyphosate was not a serious health risk and 'not likely' to cause cancer

August 2019 Briefing – Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for August 2019. This roundup includes the latest...

OxyContin Maker Purdue Pharma Is Dissolved

Sackler family to pay $4.5 billion in bankruptcy settlement, denies any personal responsibility

Very Elderly Can Benefit From Brain Tumor Surgery

While there is short-term excess mortality, cumulative survival is similar to the general population

CDC Panel Urges Seniors to Get New, More Potent Flu Shot This Fall

Agency urges all Americans aged 6 months and older to get a flu shot every season

Oral Immunotherapy With Boiled Then Roasted Peanuts Feasible

Sequential approach is feasible and safe for peanut allergy, with very low frequency of rescue epinephrine use

CDC: Vaccinated More Likely to Die During Omicron Wave If They Got J&J Shot

However, breakthrough infections among J&J vaccine recipients were similar or lower compared to the other vaccines

Serum Elaidic Acid Levels Tied to Dementia, Alzheimer Disease

Higher serum elaidic acid levels linked to increased risk for all-cause dementia, not vascular dementia

Sleep-Disordered Breathing Tied to Insulin Resistance in Pregnancy

In pregnant women with BMI ≥27 kg/m², respiratory event index and oxygen desaturation index linked to HOMA-IR

Minorities Less Likely to Undergo MRI After Elevated PSA Test

Disparities in subsequent MRIs more pronounced at higher PSA thresholds

2018 Health Care Spending Up Due to Higher Prices

2018 uptick in utilization first seen in years, but impact dwarfed by price increases

Lopinavir-Ritonavir No Benefit in Adults With Severe COVID-19

No benefit seen in time to clinical improvement, mortality at 28 days compared with standard care alone

Black Americans More Likely to Know Someone Who Has Died of COVID-19

Poll's findings highlight significant racial differences in how Americans are being affected by the pandemic

Meta-Analysis Links PTSD to Increased Dementia Risk

Risk up in veterans and general population, remains significant after exclusion of high-bias studies

DDW: Cannabinoid Use Ups Sedation Requirements During Endoscopy

However, patients with cannabis use do not have increased awareness or discomfort during procedures

Moderate-to-Late Preemies Likely Go Home at 36 Weeks

Those who are small for gestational age or have specific diagnoses may stay longer

WHO Slams COVID-19 Booster Shots in Wealthy Nations

Agency calls for a moratorium on booster shots until at least the end of September

Liver Transplant Outcomes Worse for Nonoverweight NAFLD Patients

Outcomes worse before and after liver transplant for nonoverweight versus overweight/obese adults with nonalcoholic fatty liver disease

Younger Women With AMI Have More Adverse Outcomes After Discharge

Sex differences seen for coronary-related and noncardiac hospitalizations in year following discharge

Infants of COVID-19-Infected Mothers Doing Well in Short Term

No differences seen in rates of preterm birth, NICU admission, respiratory disease with infection

Exposure to Greenspace Linked to Lower Risk for Pediatric-Onset IBD

Risk reduced for both ulcerative colitis, Crohn disease; linear dose response seen across increasing quartiles of greenspace

Global Maternal, Fetal Outcomes Worsened During COVID-19 Pandemic

Increase seen in stillbirth and maternal deaths, surgically managed ectopic pregnancies, and maternal depression

More Lung Injury Seen With Vaping Cannabis Versus Vaping, Smoking Nicotine

'Wheezing or whistling' in chest nearly two times higher among teens who had used cannabis in electronic nicotine delivery systems

Americans Have High Trust in Health Care Providers: Poll

Trust in health care providers could be an important factor in efforts to boost COVID-19 vaccination rates

Flu Cases Already Up 23 Percent This Season: Walgreens

Significant increase shown by the company's analysis of its own data reflects the historically low levels of flu last year

Ten Infant Deaths Linked to Fisher-Price Rock ‘n Play Sleepers

All infants died after rolling from their back to their stomach or side while unrestrained

Pandemic Worsened Mental Health, Social Risk in Minority Children

Depression/anxiety problems increased for urban, racial- and ethnic-minority children during versus six months before the pandemic

Infant Screen Use Linked to Alterations in Cortical EEG Before Age 2

Link between infant screen time, executive functioning at school age partially mediated by frontocentral and parietal theta/beta ratios

November 2019 Briefing – Gastroenterology

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for November 2019. This roundup includes the latest...

Wearables Detect Physiologic Changes at COVID-19 Symptom Onset

Alterations seen in basal heart rate, heart rate response to physical activity, circadian variation in heart rate, autocorrelation of heart rate

Brepocitinib Beneficial for Moderate-to-Severe Psoriatic Arthritis

Significantly greater ACR20 response rates seen at week 16 for 30 and 60 mg QD versus placebo; response maintained or improved at 52 weeks

CDC: GI, Respiratory Illnesses More Likely in Low-Income Children

But likelihood of missing any school days during the previous year decreased with reduced income

Drive-Through IOP Screening Clinic Feasible During COVID-19

Intraocular pressure screening clinic allows for continued management, including necessary changes in management

Mortality Increased in Association With SARS-CoV-2 U.K. Variant

Mortality hazard ratio was 1.64 in association with infection with VOC-202012/1 versus infection with previously circulating variants

SPPADE Symptoms Common in Cancer Patients

Co-occurrence of symptoms also very common across cancer types

Fentanyl Is Main Agent in Fatal Pediatric Opioid Poisoning

5 percent of deaths from opioids in 1999 were from fentanyl compared with 94.0 percent of opioid deaths by 2021

Lower BMI Cutoff Tied to Endometrial Cancer in Chinese Women

Lower obesity threshold of BMI ≥25 kg/m2 tied to increased risk of endometrial cancer in Asian women presenting with postmenopausal bleeding

Stem Cell Transplant Reviewed for Peripheral T-Cell Lymphoma

Three- and five-year overall survival similar with allogeneic or autologous HSCT, but transplant-related mortality higher with allogeneic HSCT

Low Specificity Limits Use of Focused Cardiac Ultrasonography

FoCUS may help rule out ventricular dysfunction, valvular disease in low-risk patients