Young Child Goes to ED for Medicine Poisoning Every 10 Minutes
Safe medicine storage in the home needs to begin well before infants are on the move
Stress Test-Based Physiological Age May Be Superior Mortality Predictor
Physiological age based on exercise stress testing performance better predictor than chronological age
Four Million New Peds Asthma Cases Attributed to NO2 Annually
Burden of new pediatric asthma cases accounts for 13 percent of global incidence
Many NPs Unable to Prescribe Meds to Treat Opioid Addiction
Greater practice restrictions lead to lower percentage of NPs with waivers to prescribe buprenorphine
FDA: High Levels of Heavy Metals Found in Kratom Products
Products contain levels of lead and nickel at concentrations that exceed safe daily intake
Considerable Proportion of ICU Admissions May Be Preventable
ICU hospitalizations for ambulatory care-sensitive conditions have decreased during a 10-year period
Care at High-Volume Facility May Cut Mortality in Multiple Myeloma
Mortality did not differ for those treated by NCICCC MM specialists, highest-volume community oncologists
OCT Imaging Needle Can Detect Blood Vessels in Neurosurgery
OCT probe integrated into standard brain biopsy needle IDs vessels with high sensitivity, specificity
Increase Seen in Amphetamine, Opioid Use in Pregnant Women
Increase in amphetamine-, opioid-related deliveries disproportionate between rural vs. urban counties
Total Fertility Rates Vary by State
Total fertility rate for U.S. 16 percent less than number needed to replace population
Recent Nasal Preps Less Effective Than Injected Vax for Flu in Kids
Quadrivalent live attenuated flu vaccine less effective than inactivated vaccine for influenza A/H1N1pdm09
Ertugliflozin Seems Safe, Effective for Type 2 Diabetes Treatment
Improvements seen in HbA1c, fasting glucose, body weight, blood pressure over two years
Outcomes of Importance ID’d for Peritoneal Dialysis Patients
PD-related infection, mortality, fatigue are highest-ranked outcomes for patients, caregivers
Low Vitamin D Tied to Risk for Renal Hyperfiltration in Healthy Adults
Severe deficiency linked to increased prevalence of RHF in population with normal renal function
FDA Investigating Paclitaxel-Coated Balloons, Paclitaxel-Eluting Stents
Investigation triggered by meta-analysis showing possible increased mortality in PAD patients at 2 years
No Asthma Benefit Seen With n3PUFA in Overweight Teens
Overweight/obese teens, young adults taking supplements do not have improved asthma control
Likelihood of Engaging in Choking Game Higher in Troubled Teens
History of depression, conduct disorders in teens associated with participating in choking game
Pregnancy-Adapted Algorithm Avoids Diagnostic Imaging for PE
Suspected pulmonary embolism safely ruled out in some pregnant women with diagnostic algorithm
Knee Pain Not Tied to Activity Levels in Knee Osteoarthritis
Neither inverted KOOS-pain nor P4 pain scale tied to physical activity
Model Can Predict Survival in Nonmetastatic Prostate Cancer
Model demonstrated good discrimination for 15-year prostate cancer-specific mortality in validation cohorts
STI Incidence Up After Receipt of HIV Preexposure Prophylaxis
Younger age, greater partner number, group sex, but not condom use, linked to increased risk of STI
Seniors Less Likely to Receive or Have Timely PCI for Acute MI
Patients >65 years of age have increased incidence of cardiac arrest, in-hospital mortality
Most Osteoporosis Guidelines Do Not Discuss Patient Choices
When patient beliefs, values, preferences are cited, they are not usually supported by evidence
United States Will Keep Measles Elimination Status
Elimination status can be removed by the WHO when measles has been spreading continuously for a year
Food Insecurity Prevalent Among Medicare Enrollees
Odds of food insecurity up with reporting four or more chronic conditions, depression, anxiety
No Big Increase Seen in Loneliness During U.S. COVID-19 Outbreak
Overall, older adults reported less loneliness compared with younger age groups
Shifting Pattern Seen for Primary Care Office Visits
Primary care physician visits down, but visits to nurse practitioners, physician assistants up
Artificial Intelligence Can Use Routine ECGs to ID Heart Disease
Those with positive AI screen four times more likely to develop future ventricular dysfunction
Obesity Linked to Lower Gray Matter Brain Volume
Combination of overall obesity and central obesity linked to lowest gray matter volume
Rituximab Beneficial in Secondary Progressive MS
Treatment with rituximab linked to lower Expanded Disability Status Scale score, delayed progression
Sex Differences Seen in Pursuit of Interventional Cardiology Career
Factors negatively influencing women are largely related to the culture of the subspecialty
EMS Treatment for Possible Heart Attack Varies by Sex
Women less likely to receive aspirin, resuscitation, ambulance transport with lights and siren
More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids
Significant increases seen in death rates involving synthetic opioids in 15 of 20 states from 2013 to 2017
AHA: Nearly Half of U.S. Adults Have Cardiovascular Disease
Forty-six percent of U.S. adults have hypertension
Intensive BP Treatment Does Not Reduce Dementia Risk
But drop seen in risk for MCI and combined rate of cognitive impairment, probable dementia
Texting Intervention Engages Patients After Joint Arthroplasty
Patient outcomes improved compared with traditional perioperative education
Cancer Risk Modestly Elevated With Chronic Kidney Disease
Lower eGFR linked to elevated cancer risk relative to eGFR of 90 to 104 mL/min
Testosterone Therapy in Hypogonadism Can Prevent Progression to T2DM
Men with prediabetes, hypogonadism achieved normal glucose regulation with TTh
Mumps Causes Quarantine of Over 2,200 Immigrant Detainees
25-day quarantine affects facilities in Pine Prairie, Louisiana, and Aurora, Colorado
Mindfulness Yoga Aids Patients With Parkinson Disease
Effects similar to those of stretching and resistance training for motor dysfunction, mobility
Chloroprocaine Offers Adequate Anesthesia for Knee Arthroscopy
Shorter time to complete recovery from motor blockade seen for chloroprocaine compared with prilocaine
Female Infertility Specialists Make Less Than Male Specialists
Findings remain significant even when accounting for years in practice and type of practice
Mortality Down for Autoantibody-Associated Vasculitides Patients
Average annual decline of 1.6 percent in AAV-related mortality rate seen from 1999 to 2017 in the U.S.
Risk Tool Can Predict Heart Failure in Patients With Diabetes
AI model integrates readily available clinical, laboratory, and electrocardiographic data
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
Targeted Hep C Testing Misses High Number of Cases in Prisons
Findings based on birth cohort, risk-based testing versus opt-out testing in prison system
U.S. Food Supply May Be at Risk Due to Government Shutdown
Number of routine food inspections performed by the FDA dropped sharply
AI Technology IDs Genetic Diseases by Analyzing Facial Photos
DeepGestalt technology better than doctors at identifying a range of genetic syndromes
Functional Milestones Identified for Persons With Down Syndrome
Most maintain personal hygiene by age 13, work independently by 20; 34 percent live independently
Complications Higher Than Expected for Invasive Lung Tests
Complication rates for invasive lung diagnostic procedures higher than those seen in clinical trials
Most Nurses Unsatisfied With Hospitals’ End-of-Life Care
The nurse practice environment was the best predictor of poor-quality end-of-life care
Mandated Neonatal Abstinence Reporting Helps Quantify Cases
Five of six states with mandatory reporting receive case reports within 30 days of diagnosis
Off-Label Uses in Dermatology Often Missing From Compendia
Only 30.7 percent of 238 treatments used to treat 22 dermatologic conditions listed in compendia
Gender Gap Seen in Accessing Alcohol Treatment With Cirrhosis
Women less likely to be treated than men; treatment visit, medication tied to improved one-year outcomes
Measles Outbreak Prompts Public Emergency in Washington State
23 measles cases confirmed and two more suspected cases under investigation
Mental Health Issues Have Risen in Teens, Young Adults
Rates of depressive episodes, serious psychological distress, suicide-related outcomes have increased
Tramadol May Up Mortality Risk in Osteoarthritis Patients
Findings for those initially prescribed tramadol compared with commonly prescribed NSAIDs
Inflammatory Arthritis Linked to Sexual Dysfunction
Themes of impaired sexual function, compromised intimate relationships ID'd in studies of IA patients
Early T2DM Diagnosis Linked to Increased Cardiovascular Risk
Highest excess risk for mortality, CV mortality, heart failure, CHD seen for T2DM patients diagnosed before 40
Drop Seen in Preinvasive Cervical Disease With HPV Vaccination
Vaccine effectiveness increased for immunization at younger age
Medicaid Pays 75 Percent of What Medicare Pays for Spine Surgeries
Study authors report differences in reimbursement for certain procedures may impact access to care
Smartphone-Operated One-Lead ECG Detects A-Fib, Flutter
High sensitivity, specificity demonstrated for atrial arrhythmia
Uptitration of Drugs Varies With Target Dosage in Chronic HF
When target is higher versus lower dosage, uptitration stops further from recommended dosage
Restrictive, Obstructive Lung Disease Linked to Dementia Risk
Associations seen for both Alzheimer's disease-related dementia and cerebrovascular etiologies
For Teen Girls, Depression May Predict Subsequent Alcohol Use
Depression severity predicts increased likelihood of alcohol use; link for reverse pathway inconsistent
Chemo-Radiation Combo Tied to Higher Survival in Peds Hodgkin
Five-year overall survival higher in patients who receive combined tx than those treated with chemo alone
Employment, Earning Losses Noted After Cardiovascular Events
Fewer patients admitted to hospital for MI, cardiac arrest, stroke working at three years postevent
Temporary Impairment in HRQOL After Teen Sports Concussion
Worse cognitive HRQOL and clinically meaningful impairment in school and overall HRQOL observed
Incident Concussion 5.1 Percent Per Season for Youth Football
Risk increased for youth with depression or history of concussion
More Americans Reporting Less Than Six Hours Sleep Per Night
The number of Hispanics, blacks getting short sleep is growing at a fast rate
Variation in Revascularization for Asymptomatic SIHD Unexplained
Consistent benefit observed for patients with stable ischemic heart disease managed by revascularization
Hand Hygiene Compliance Low Among EMS Providers
Use of hand rub or hand wash seen in 3 percent before, 29 percent after patient encounters
2003 to 2015 Saw Increase in Outpatient Benzodiazepine Use
Fourfold increase seen in rate of coprescribing with opioids; twofold increase with other sedating meds
Recommendations Issued for HSCT in Multiple Myeloma
Autologous stem cell transplant remains essential component of MM therapy in eligible patients
AAOS: Underweight Status Increases Shoulder Arthroplasty Complications
Physicians, health care systems should pay more attention to this 'extremely at-risk population'
Waiting Room Tool Aids Patient-Physician Communication
Tool helps patients to prepare questions and prioritize concerns prior to seeing primary care doctor
Complication Rates Low for High-Volume Pediatric Thyroid Surgery
Low complication rates for surgical management of pediatric thyroid disease at high-volume center
Ten Infant Deaths Linked to Fisher-Price Rock ‘n Play Sleepers
All infants died after rolling from their back to their stomach or side while unrestrained
Computer Model Predicts Risk for Ventricular Arrhythmia in ARVC
Clinical benefit of model was superior to current consensus-based ICD placement algorithm
Three-Drug Single Inhaler Treats Uncontrolled Asthma in Adults
Findings seen in two large international clinical trials comparing three-drug inhaler to two-drug inhaler
NIH Stops Hydroxychloroquine Trial
Although there was no harm, data and safety monitoring board found the drug 'very unlikely to be beneficial'
Impact of Fructose Varies With Energy Control, Food Source
Harmful effects for sugar-sweetened beverages when excess energy from sugar added to diet
Statin Therapy Reduces Risk for Diabetic Retinopathy in T2DM
Reduced risk, slowed progression of retinopathy for Taiwanese patients with type 2 diabetes, dyslipidemia
Fewer Than 5 Percent of Thyroid Surgery Patients Readmitted
Majority of readmissions occur within seven days of discharge and one-fourth within two days
Screening Donated Blood for Zika Not Cost-Effective
Universal mini-pool nucleic acid testing only during high mosquito activity cost-effective in Puerto Rico
Personalized Tx May Extend Life in CKD With Small Renal Tumors
Routine partial nephrectomy yielded longest life expectancy in patients with normal renal function
HPV Ups Cervical Cancer Risk, Even With No Cellular Signs
HPV-16/18 confers strong future risk, particularly in women younger than 30 years
Delayed School Start Shows Benefits for Teens
Longer sleep time tied to better grades, some improvements in attendance
Fruit, Vegetable Intake Very Low in Hemodialysis Population
Higher consumption of fruit and vegetables linked to lower risk for all-cause, non-CVD mortality
NOACs Recommended as First-Line Prevention of Stroke in A-Fib
Updated guidelines also emphasize weight loss for overweight, obese patients with atrial fibrillation
Suicide Incidence Up in Autism Spectrum Disorder 2013 to 2017
Difference driven by suicide among women, which was more than threefold higher
ACC: Dietary Cholesterol Ups Cardiovascular Disease Risk
Findings show dose-response increase in risk for cardiovascular disease, all-cause mortality
Guidelines Developed for Polymyxin Antibiotic Use
Polymyxin B recommended for routine use in invasive infections; colistin preferred for lower UTI
Short Regimen Noninferior for Rifampin-Resistant Tuberculosis
Short regimen of nine to 11 months noninferior to 20-month regimen following WHO guidelines
CDC: Prevalence of Autism at Age 4 Years Increasing
Frequency of co-occurring intellectual disabilities higher among children aged 4 years than 8 years
FDA Approves Osteoporosis Tx for High-Risk Postmenopausal Women
Boxed warning states increased risks for cardiovascular death, stroke, heart attack
Calcium Intake Tied to Lower Rate of Late AMD
Patients encouraged to continue taking calcium if needed for other indications
Increasing Intake of Any Sugary Drink Ups Diabetes Risk
Substituting one sugary drink daily with one water, coffee, or tea lowers risk
Ligelizumab Safely, Effectively Treats Hives
Doses of 72 mg or 240 mg tied to complete control of symptoms after 12-week trial
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
New BP Goals Could Prevent 3 Million CVD Events Over 10 Years
Maintaining ACC/AHA goals would result in fewer events than current BP levels, prior guideline goals
Flu Vaccination Safe for Hospitalized Patients
With vaccination, risks reduced for readmission, outpatient visits, fever, clinical evaluations for infection
Costs Higher for Those With Comorbid Noncommunicable Diseases
Health expenditure greater for person with two diseases simultaneously than for the diseases separately
In-Hospital Morbidity, Mortality Up With Flu in Heart Failure
Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury
Low-Income Women Lack Menstrual Hygiene Supplies
One in five low-income women in St. Louis cannot afford products on a monthly basis
Appalachia, Western States Have Highest Hep C Prevalence
Nine states account for more than 50 percent of all hepatitis C virus infections
Medication Treatment for Substance Abuse Up in Facilities
2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016
ASA: Flu-Like Illness Linked to Increased Risk for Stroke
Second study shows patients more likely to have ILI within 30 days preceding cervical artery dissection
Bone Health in Older Adults Not Improved by High-Dose Vitamin D
25(OH)D concentration increases with supplements, but no difference in BMD changes among three doses
Fried Chicken, Fish Linked to All-Cause, Cardiovascular Death
For postmenopausal women, mortality risk increased with one serving fried chicken/fish per week
AAP: Nasal Spray Vaccine Against Flu Acceptable in 2019 to 2020
Based on current data, AAP Board of Directors says either injection or nasal spray vaccination OK
Four-to-Seven-Day Opioid Rx Likely Sufficient for Acute Pain Treatment
No more than one in five patients who filled an opioid analgesic prescription obtained a refill
Myoelectric Computer Interface Beneficial for Stroke Survivors
MyoCI well tolerated, can reduce abnormal coactivation in stroke survivors with arm impairment
Model Can Predict Sepsis Risk for Emergency Medical Admissions
Computer-aided National Early Warning Score model makes use of data already collected by clinicians
CDC: Violence Against Seniors on Rise, Especially Among Men
Nonfatal assault rate increased 75.4 percent among men from 2002 to 2016
Hepatitis C Virus Infection Rates Up for Women Giving Birth
Rates of HCV infection are much higher among women with opioid use disorder
Johnson & Johnson Settles Opioid Suit With Two Ohio Counties
Drug maker agrees to pay Cuyahoga and Summit counties $10 million without admitting liability
Overlapping Orthopedic Surgery Noninferior for Patient Safety
Reduced odds of perioperative complications seen for overlapping surgery versus nonoverlapping surgery
Bone Indices on CT Scan Predict Fracture Risk in Older Adults
Peripheral CT indices address risk for fracture contributed by changes in bone microarchitecture
Increase in Brand-Name Drug Cost Mainly Due to Existing Drugs
Rising costs of oral, injectable generic and specialty drugs mostly driven by new product entry
Meta-Analysis: Botulinum A Tops Placebo for Chronic Migraine
Frequency of chronic migraines significantly reduced after three months; QoL improved
Prevalence of Knee OA Lower With Menopausal Hormone Therapy
Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model
CDC: Weight, Waist Size, BMI Increased for Many U.S. Adults
1999-2000 to 2015-2016 saw increase in mean weight, waist circumference, BMI for many subgroups
Opioid Prescribing Patterns Vary for Pediatric Patients
Geographic region, race, age, payment method associated with differences in opioid prescribing
Oral Hepatoselective Glucokinase Activator Promising in T2DM
Clinically significant and sustained reduction in glycated hemoglobin was observed with TTP399
Aerobic Exercise Tied to Better Cognition at All Ages
Effect seen as young as 20 years, although the effect is greater with increasing age
Home-Based Program Achieves Hypertension Control
Program uses Bluetooth-enabled monitoring, patient coaching by nurse practitioners and pharmacists
Sugary Drinks Tied to Cardiovascular Disease Mortality
Comparing extreme categories of consumption, SSB linked to increased CVD mortality, cancer mortality
Average of 283,000 Children Have Sports-Related TBIs/Year
From 2010 to 2016, average of 283,000 children sought care in EDs for SRR-TBIs
CDC: 228 Measles Cases Already in 2019
Number of cases in the United States so far this year getting close to the total number for all of 2018
Caregiving for Older Cancer Patients Takes Emotional Toll
Poorer patient health tied to higher levels of caregiver distress among informal caregivers
Telemedicine Leads to More Antibiotic Rx for Pediatric Respiratory Infection
More antibiotics prescribed with less guideline-concordant antibiotic management versus other settings
FDA Issues Warning on E-Cigarette Liquids Resembling Cough Syrup
Products have labeling, advertising that imitate prescription cough syrup products
Changes in Air Pollution Levels May Affect Risk for Preterm Birth
For second pregnancy, risk higher among low-risk women with high, persistent air pollution exposure
Many U.S. Counties Lack Infectious Disease Specialists
Among 785 counties with highest quartile of COVID-19 burden, 66.4 percent have no ID physicians
Core Language Skill Stable From Infancy to Adolescence
Consistency in core language skill is stable through childhood in typically, atypically developing children
Drug Repurposing May Provide More Psychiatric Tx Options
Three drug classes tied to lower rates of self-harm and psychiatric stays with serious mental illness
Smartphone App Can Detect Early Signs of Opioid Overdose
App has high sensitivity, specificity for opioid-induced central apnea, respiratory depression
Rx Opioids Up Pneumonia Risk in Patients With, Without HIV
Risk greatest with higher-dose opioids and opioids with immunosuppressive properties
Coronary Artery Calcium May Help Predict CVD in South Asians
CAC incidence similar in South Asian men versus white, black, Latino men; higher than Chinese
FDA Approves Drugs for Treatment of Two Rare Blood Diseases
Elzonris approved to treat BPDCN; Ultomiris approved for paroxysmal nocturnal hemoglobinuria
Review Highlights Lack of Tx Options for Prurigo Nodularis
Researchers call for more randomized controlled trials to investigate systemic treatments
Symptom Combos Suggesting Laryngeal Cancer Identified
10 features of laryngeal cancer with which patients presented in year before diagnosis identified
Depressive Symptoms Higher During Internal Medicine Internship
Faculty feedback, learning experience in inpatient rotations, work hours tied to change in symptoms
Cognitive Scores After Kidney Transplant Tied to Frailty
Cognitive function first improved then declined 1 to 4 years after transplant in frail recipients
ACC: Antibacterial Envelope Can Reduce CIED Infections
Incidence of major cardiac implantable electronic device infections significantly lower with envelope
Less Invasive Method Safely IDs Epilepsy Surgical Candidates
Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases
Head of National Cancer Institute Named Acting FDA Commissioner
Current commissioner, Scott Gottlieb, will be stepping down in April
Older Adults With Hearing Loss Have Lower Patient Activation
Even those with 'a little trouble' hearing have higher risk for low activation than those with 'no trouble'
Dietary Supplement Use Not Linked to Mortality Benefits
Excess calcium intake may increase risk for cancer death; link related to supplemental calcium intake
No Benefit Seen With Rituximab for Chronic Fatigue Syndrome
B-cell depletion using several rituximab infusions over 12 months not linked to clinical improvement
Indoor Tanning May Up Risk for Squamous Cell Carcinoma
Dose-response association found between indoor tanning and SCC risk among women
Hyperemesis Gravidarum Linked to Autism Spectrum Disorder
Rates of ASD increased for children exposed to HG in utero; risk up for boys, girls, whites, Hispanics
Physician’s Briefing Weekly Coronavirus Roundup
Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...
Risk of Sudden Death in Epilepsy Can Decline Over Time
Those with a low risk for SUDEP generally remain in this categorization during three years of tracking
Less Deep Sleep in Elderly Tied to Alzheimer Disease Markers
Poor-quality sleep in later life could be a noninvasive marker for deteriorating brain health
Racial Differences ID’d in Some Biomarkers of Alzheimer’s Disease
African-Americans have lower mean CSF concentration of total tau, phosphorylated tau181
Sex Differences ID’d in Response to Glioblastoma Treatment
Standard therapy more effective for female versus male patients with glioblastoma
High Levels of Activity, Motor Ability Linked to Better Cognition
Findings seen in older adults; independent correlations remained for those with Alzheimer disease
Complications, Costs Up With Cardiac Sx in Opioid Use Disorder
No increased risk of mortality, but increase in incidence of major complications
FDA Panel Has Tie Vote on New Type 1 Diabetes Drug
Zynquista is a once-daily pill meant to help type 1 diabetes patients manage their blood glucose levels
FDA Receives an ‘F’ in Tobacco Prevention Report Card
American Lung Association releases State of Tobacco Control 2019 report
Adverse Birth Outcomes Up With Medically Assisted Reproduction
But risks are mainly attributable to factors other than medically assisted reproductive treatment
Time to Breast Cancer Surgery Delayed for Non-Hispanic Blacks
Racial differences in TTS did not explain racial differences in overall survival with breast-conserving sx
Intervention Promotes Better Conversations With Cancer Patients
But communication quality-improvement intervention does not improve patient outcomes
Parent Perception of E-Cig Safety Varies With Smoking Habits
Most who smoke cigarettes and e-cigs have smoke-free home policies; fewer have vape-free policies
Review Links Adverse Events to Use of Herbal Meds in Pregnancy
Increased odds of preterm birth with almond oil; oral raspberry leaf linked to cesarean delivery
Variation ID’d in Rate of Sexual Onset Before 13 Among Boys
Likelihood of reporting sexual intercourse before 13 lower for boys whose mothers have college degree
Older Patients With Vision Loss Have Higher Hospital Use, Costs
Similar findings seen among patients with commercial insurance
Food Insecurity Linked to Chronic Disease in Young Adults
Second study shows food insecurity linked to mental health problems, poorer sleep outcomes
Monitoring HTN Med Adherence Does Not Improve BP Control
Text messaging and remote monitoring can aid adherence but not blood pressure control
Asthma-Related ED Use Up for Children With Anxiety, Depression
Children with asthma and anxiety, depression, or both have increased rates of asthma-linked ED use
Hospitalization for Upper GI Bleed Highest With Rivaroxaban
Upper gastrointestinal bleeding hospitalization risk lower for anticoagulant tx with PPI cotherapy
Presence of Antiphospholipid Antibodies Tied to First-Time MI
With validation, findings may impact management, outcomes of high-risk patients
No Increased Fall Risk With HTN Treatment in Older Women
Lower incidence rate ratios found for women with treated controlled hypertension, treated uncontrolled HTN
Exercise Can Consistently Lower Blood Pressure
Reductions in BP from exercise comparable but not as great as from medications
Hemochromatosis Mutation Linked to Other Morbidity
Higher rates of at least one incident-linked condition seen in men, women with HFE p.C282Y homozygosity
Mental, Behavior, Developmental Disorders Up With Low-Income
Children in lower- versus higher-income households more often diagnosed with MBDDs
Elevated Risk for Lung CA in Lung Transplant Recipients Explored
13-fold increased risk found in native lung for those receiving single lung transplant
Mandibular Contour Surgery Training System Beneficial
Improvements in clinical surgery time, accuracy with use of intraoral MCS training system
Prophylaxis for Gonococcal Eye Infections in Newborns Advised
USPSTF reaffirms use of antibiotic ointment to prevent gonococcal ophthalmia neonatorum
Psychopathology in Adulthood Up With Child Lead Exposure
Higher childhood blood lead levels linked to increase in general psychopathology
Antiepileptic Drugs Not Tied to Dementia Risk
No increased overall risk found, but levetiracetam generic brands tied to higher dementia risk
CDC: 2000 to 2017 Saw Increase in Mortality Due to Dementia
Age-adjusted death rate was 66.7 deaths per 100,000 U.S. population in 2017
Diet Quality in Midlife Not Linked to Later Risk for Dementia
No significant difference in incidence rates for dementia according to measures of diet quality
2000 to 2015 Saw Increase in Liver Cancer Mortality
Increase generally steeper in less educated women; confined to men with ≤15 years education
First Two-Drug Regimen Approved for HIV-1 Treatment
Dovato indicated for use in patients with no history of antiretroviral treatment
Back Sleeping in Late Pregnancy Linked to Lower Birth Weight
Authors say this is a modifiable risk and campaigns should target third-trimester side sleeping
Factors Predict Low BMD in Pediatric Blood Cancer Survivors
Low bone mineral density detected during guideline-recommended dual-energy X-ray absorptiometry
Children’s Robitussin Honey Cough and Chest Congestion DM Recalled
Dosing cups missing some graduation markings
CDC: Acute Flaccid Myelitis Cases Appear to Have Peaked for 2018
As of Nov. 30, 134 cases of AFM have been confirmed in 33 states
Persistent Opioid Use High in Head, Neck Cancer Patients
Opioid use before treatment, tobacco use are risk factors for ongoing opioid use