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Anthony Fauci, M.D., spoke with HD Live! about the safety and efficacy of a COVID-19 vaccine and doubling down on efforts to stop the surge in cases

Increase seen across women of all ages, Hispanic origin groups, educational levels

Behavioral counseling interventions to promote healthy diet and physical activity have moderate net benefit

And, physical activity associated with improvements in depression and mental and physical HRQoL after RYGB

Rate of progression from MCI to AD increased with ApoE4, anxiety, lower hippocampal and entorhinal cortex volumes

Accuracy of 82 percent achieved with DeepCOVID-XR compared with 81 percent for consensus of five thoracic radiologists

Vaccine appears 95 percent effective at preventing mild-to-severe COVID-19, according to the manufacturers

Delirium is the sixth most common presenting symptom/sign; delirium linked to ICU stay and death

Company admits paying doctors to write more prescriptions, providing misleading information to the DEA

Risk reduced with previous and current use of any and combined hormonal contraceptives, not with progestogen-only use

Practice separation most common among early- and late-career radiologists, general radiologists

Findings based on randomized trial evaluating initial treatment with cryoballoon catheter ablation versus standard meds

The 2020 Annual Meeting of the American College of Allergy, Asthma & Immunology

Second study shows benefits among patients with type 2 diabetes and chronic kidney disease, risks for CVD

Prenatal care is an important time to screen for hepatitis C, authors say

Influenza infection and symptoms occurred in 1 and 13 percent of those receiving Xofluza and placebo, respectively

Tests recommended one to three days before the flight, three to five days after the flight, and one to three days before returning

Risk reduction driven by improvement in insulin resistance, lipoprotein metabolism, and inflammation

Oxlumo granted approval to treat primary hyperoxaluria type 1

Some volunteers in trials of candidate vaccines have reported flu-like symptoms after immunization

Black, Hispanic, Asian children less likely to get tested for SARS-CoV-2, more likely to test positive than White children

In patients with critical findings identified on neuroimaging, most common comorbidities were hypertension, diabetes

Seroprevalence of anti-SARS-CoV-2 IgG lower for health care workers with history of BCG vaccination

7 percent of mothers delivering at large county health system tested positive, as did 3 percent of tested infants

Risk for in-hospital death, mechanical ventilation higher for obese patients; link between BMI and outcomes strongest for adults ≥50 years

OHCA outcomes worse early in the pandemic even in areas with low case-fatality rates

Long-term oxygen therapy strongly recommended for adults with COPD, ILD who have severe chronic resting hypoxemia

New hepatocellular carcinoma cases highest among rural Hispanic residents

Excess deaths seen for specific gender and age groups, with protective effect seen for female children

Overall rate of contraceptive use 5.3 percent of person-years

AAO 2020 Virtual

IV infusion of casirivimab and imdevimab authorized for treatment of mild-to-moderate COVID-19

Immunogenicity similar across age groups; vaccine better tolerated in older versus younger adults

Evidence to date has not shown clinically important effects on mortality, need for mechanical ventilation

The AstraZeneca vaccine becomes the third to show good effectiveness

Mortality, MACE rates among patients hospitalized with COVID-19 did not differ by race, ethnicity

Projected future increases in cirrhosis due to alcohol-related liver disease and nonalcoholic fatty liver disease

Findings seen among adults with out-of-hospital cardiac arrest and refractory ventricular fibrillation

Just over half of patients with type 2 MI seen by a cardiologist in hospital; most did not see a cardiologist for follow-up care

Cognitive prehabilitation reduced delirium among older adults undergoing major noncardiac surgery

Test demonstrates good performance for rapid diagnosis of periprosthetic joint infection around joint implants

Most common late effects were endocrine, cardiovascular, respiratory; likelihood of late effects up for those who underwent HSCT

Association attenuated slightly with adjustment for dietary calcium and/or protein but still significant

More than one-third of cancer survivors reported social needs, with highest prevalence for food insecurity

American Heart Association President-Elect Donald Lloyd-Jones, M.D., discussed highlights of the AHA Scientific Sessions 2020 with HD Live!

Lung cancer screening at the state level does not correlate with lung cancer burden

Most respondents report being moderately confident about principles of peritoneal dialysis, but few had initiated urgent-start PD

Emergency use authorization applies to hospitalized patients requiring supplemental oxygen, mechanical ventilation, ECMO

People of color face worse outcomes, have lower likelihood of being diagnosed early, receiving surgery

No significant benefit seen for high-dose versus standard anticoagulation therapies, may be harmful

Office-based visits decreased from before 2020 to during pandemic, but telemedicine visits increased in 2020 Q1, Q2

Gleason grade, prostate-specific antigen velocity, and imaging markers predict cancer spread

Increased risk for serious childhood infection following elective, emergency cesarean section persisted to five years

Pulmonary embolism and major bleeding linked to increased mortality risk

Association seen in older women persisted even at PM_2.5 levels below U.S. regulatory standards

Presurgery depression, anxiety, catastrophizing tied to more pain after joint replacement surgery

Specifically, perceived support of family members significantly tied to less distress among low-income patients

Prevalence of any current tobacco product use up for men; adults aged ≤65 years; lesbian, gay, bisexual adults

ACR Convergence 2020

Large U.K. study shows more teens are dieting, overestimating their weight

Survey of nearly 5,000 young adults reveals link between job insecurity and self-reported anxiety, depression

Display of patient photographs in electronic health records associated with decrease in WPOE errors

In 2019, TAVR exceeded surgical procedures; 30-day mortality and stroke rates decreased since 2011

No reduction seen in CV events with omega-3 versus corn oil in addition to usual background therapies, including statins

Three years after expansion, a decrease in late-stage cancers was also detectable

COVID-19 cases on the rise in all but one state

Younger patients and those with alopecia have significant disproportionality signals for increased suicidality

High-risk individuals making modest changes in weight, physical activity had lower odds of progressing to type 2 diabetes

12.3 percent of obese and overweight children with alanine aminotransferase >30 U/L received further workup for NAFLD

Interim analysis shows risk for disease progression or death lower for first-line therapy with lorlatinib versus crizotinib

Prolonged auditory brainstem response phase, V-negative latency seen in newborns with autism spectrum disorder

48.4 percent decrease found in HIV-related death rates and 8.6 percent decrease seen in non-HIV-related death rate

Histology slides, clinical data used to predict immune checkpoint inhibitor response in advanced melanoma

Obesity and hypoxia on admission predictive of severe respiratory disease; children with MIS-C more likely to be non-Hispanic Black

United States is only country not to guarantee access to provider home visits or paid parental leave in postpartum period

On stratification by BMI, significant reduction found in incident metastatic or fatal cancer in normal weight, not overweight/obese

Findings seen among adult outpatients with SARS-CoV-2 with oxygen saturation of 92 percent or greater

Wednesday marks 42 days, or two incubation periods, since the last survivor tested negative for the virus

AAP joins six other medical groups in letter requesting transparency and communication to improve confidence in a vaccine

Longest delay of five to eight months found for users of injectable contraceptives; no lasting effect seen on fecundability for long-term use

Increase in risk for moderate-severe asthma observed in morning chronotypes working irregular shifts, including nights

Genetic signature tied to doubled risk for developing potentially fatal blood clots in one in seven IBD patients

Progression-free survival longer with once-weekly selinexor-containing regimen versus standard bortezomib and dexamethasone

Simple nasal swab test requires prescription; people younger than 14 cannot perform the test on themselves

Significant reductions seen in primary outcome for use of polypill and polypill plus aspirin combination

Recommendations and practice points relate to comprehensive care needs, glycemic monitoring, lifestyle interventions

Immunoreactivity to Aggregatibacter actinomycetemcomitans serotype b, Aa leukotoxin A linked to atherosclerosis

In 54 percent of children with exercise-induced respiratory symptoms, final diagnosis differed from referral diagnosis

Indirect effect of remote NO₂ and PM_2.5 exposure on declines in episodic memory mediated by depressive symptoms

Self-reported symptoms of depression, thoughts of suicide much higher than historical norms

Authors say insurance barrier poses risks to safety, health, and well-being

29.2 percent died during hospitalization or within 60 days of discharge; ongoing morbidity was common

More than half of those recovered from acute phase of COVID-19 experience postviral fatigue, independent of COVID-19 severity

Increase in alcohol/substance-related diagnoses largest for those aged 55 to 74 years; increase in suicide-related diagnoses largest for under-18s

Only 2.1 percent of those with qualifying fractures were diagnosed and treated

Benefits of nasal swab testing seen in high-transmission areas and before major surgery

Patients with COVID-19 have slower improvement in oxygenation, longer duration of mechanical ventilation, lower rates of extubation

Abrupt increase in sedentary time seen for women, with more gradual increase for men

Findings independent of changes in demographic, economic, and health care access

In letter from three medical associations, the president is urged 'to share critical data and information as soon as possible'

For resectable colorectal liver metastases, five-year survival rates similar with laparoscopic, open surgery

Risk for childhood onset of health conditions increased for those with early-life antibiotic exposure

Adults hospitalized for COVID-19 receiving SNG001 versus placebo more likely to show clinical improvement

No increase seen in risk for occlusion of retinal artery, vein among women filling prescription for female hormone therapy

Asthma EMS dispatch rate in New York City decreased after implementation of the Affordable Care Act

Among adults with atrial fibrillation, warfarin use linked to increased odds of knee, hip replacement versus direct oral anticoagulants

This accounts for about a quarter of the total effect on blood pressure control

And LDL cholesterol-lowering therapies are effective for reducing cardiovascular events in older adults

Testicular germ cell tumor risk elevated with exposure to X-ray and CT below the waist, GI series or barium enema

AKI associated with increased odds of mechanical ventilation use, longer hospital stay, increased risk for death

Worsening was most pronounced among children with early age of onset, family history of ADHD

Authors say findings point to importance of having a diverse physician workforce

Between 11 and 18 percent of depression cases could potentially be prevented by eliminating loneliness

Among Marine Corps recruits, about 2 percent who were negative for SARS-CoV-2 at start of supervised quarantine tested positive by day 14

Manufacturers say vaccine is 90 percent effective in protecting people from the new coronavirus

Company expects to have about 20 million doses of the vaccine ready to ship in the U.S. by the end of the year

Hazard ratio 0.58 for heart failure with healthy sleep score of 5 versus score of 0 or 1

Potential years of life lost per death highest for deaths due to cancers of testis, bones/joints, other endocrine sites

Interventions could avert 3,000 to 14,000 future HPV cancers scaling to the U.S. population

The 2020 Guideline for the Management of Rheumatoid Arthritis updates guidance on drug treatments

Normal brain development and neurodevelopmental scores seen at age 2 years

Socioeconomic and regional disparities persist in the use of BRCA testing

Proportion of mental health-related ED visits increased 24 and 31 percent for children, adolescents

About one in four meet combined goals of management of blood glucose, BP, non-HDL-C, avoiding smoking

Rates of radiographic progression similar for corticosteroid injections, hyaluronic acid injections in multivariable analysis

While there was a shift toward evidence-based indications, majority of use remains off-label

For adults hospitalized in Spain with COVID-19, treatment with statins associated with lower COVID-19-related mortality

Fewer parent-reported behavioral problems observed with longer duration of breastfeeding

For seniors, vitamin D, omega-3 supplement, strength training, alone or in combination, do not improve clinical outcomes

Programs receiving intensive implementation support more likely to achieve good depression outcomes

Findings seen among teens with no previous intention to smoke conventional cigarettes

More than six in 10 board-certified cosmetic surgeons advertise procedures beyond the scope of their residency training

After steady decline in 2010 to 2016, measles cases increased in all WHO regions from 2017 to 2019; deaths increased 50 percent

73 percent of those with SARS-CoV-2 infection not hospitalized; 11 percent of those hospitalized required ICU admission

Combat-related concussion groups show clinically significant decline from one- to five-year evaluation

Rates of prepregnancy hypertension per 1,000 live births increased from 13.7 to 23.7 among rural women, from 10.5 to 20.0 among urban women

Improvements in cardiac structure, function seen at 30 weeks of treatment with mavacamten versus placebo

Nicotine e-cigarettes added to counseling improved abstinence at 12 weeks, but not at 24 weeks

Automated detection of impending clinical deterioration linked to lower mortality within 30 days after an alert

Opioid prescribing guidelines for children developed; authors underscore importance of nonopioid analgesic options, providing education to patients and their families

New weekly cases in nursing homes up by 44 percent between mid-September and week of Oct. 18

Odds of hospital readmission increased with age, presence of chronic conditions, hospitalization within previous three months

No negative impact on survival found with additional safety precautions for health care personnel during COVID-19

Higher proportion of physician visits included hypertension for adults living in rural, small-medium metro areas

IDWeek chairs Inger Damon, M.D., and Tom Talbot, M.D., discuss this year's annual meeting with HD Live!

No clinical benefit found for hydroxychloroquine versus placebo in hospitalized adults with COVID-19

The 62nd Annual Meeting of the American Society for Radiation Oncology

Variation seen by race, ethnicity, which is likely accounted for by other risk factors such as age, parity, nutritional factors

Five patients have been hospitalized; no deaths have been reported

Cancer detection rate higher for repeat screening with digital breast tomosynthesis + synthetic mammography versus full-field digital mammography

In 98.5 percent of the cases, usual child care arrangement was by a single adult in charge of one or more children

Up to 74 million U.S. adults at risk for severe infection are essential workers or live with one

Black and Latino workers have twice the odds of a positive virus or antibody test

Proportion of intentional violent injury significantly greater during peripandemic months versus prior years, especially from firearms

Internet use lower among those with hypertension and diabetes and among Blacks and Hispanics

Authors say decision support tool could help reduce antibiotic resistance by cutting use of broad-spectrum antibiotics

Of those receiving gender-affirming hormone therapy, many have CV risk factors and are not receiving appropriate therapies

But EKFC equation was developed and validated only in White populations

Prevalence of flu vaccination lower among adults aged 18 to 34, 35 to 44 years with versus without history of MI

Treatment approved for people newly infected with COVID-19 who are at high risk for progressing to severe disease

Two studies show no significant reduction in patient acceptance, adherence to virtual CR; remote CR as effective as outpatient CR

No differences seen in history of 10 chronic diseases, current health conditions, severity of psychological distress, rates of needing help with daily activities

I statement based on lack of studies examining benefits and harms of screening, impact of treatment on outcomes in adulthood

Early results of clinical trial show high rate of responders who achieved ≥50 percent pain relief

Findings most pronounced in younger women and racial and ethnic minorities

New cancer drugs approved between 2000 and 2016 associated with 1,291,769 fewer related deaths in the U.S.

Experimental drug found to be 89 percent more effective at preventing HIV infection than Truvada pills

Monthly premium for outpatient care will rise by $3.90 next year

FDA panel concluded there is not enough evidence to support the clinical effectiveness of aducanumab

Influenza vaccine coverage 26 percent lower for children of parents reported to be hesitant about childhood shots

ACG 2020 Virtual

However, there is still a gap in life expectancy, health-adjusted life expectancy between those with and without inflammatory bowel disease

Middle-aged and older Black and White adults have increased stroke risk with CES-D-4 scores of 1 to 3, 4 or more

Chest CT scans performed for other indications can identify adults with low bone mineral density

Tinnitus exacerbated for those self-isolating, feeling lonely, sleeping poorly, exercising less

Despite shorter stays, no differences seen in maternal or newborn adverse outcomes

2003 to 2016 saw fourfold increase in drug use-related endogenous endophthalmitis hospitalizations in the United States

However, patients with higher health literacy less likely to undergo PSA screening in the presence of shared decision-making

Universal genetic testing catches genetic mutations not detected in guideline-based testing

Vaccine requires two doses, given three weeks apart

More severe disability on discharge and more inpatient death reported for ischemic stroke in COVID-19 patients versus controls

From 1990, slight decrease seen in age-standardized prevalence, disability-adjusted life year rates

Cognitive decline significantly reduced for Neuropsychological Test Battery five-item composite, memory, brain atrophy measures

Curriculum covers technical, nontechnical skills necessary to care for gun violence victims

EASI score significantly lower for pediatric patients receiving vitamin D3 versus placebo with 1 percent hydrocortisone cream

Aducanumab does not cure or reverse Alzheimer disease; high dose may slow mental decline

Treating, monitoring irritated skin may prevent pressure injuries

People with depression, anxiety disorder, or bulimia more likely to exceed daily, weekly alcohol limits

Reductions reported in colonoscopies, mammograms, child vaccines, in-person office visits; telemedicine service use up in March, April 2020

Decreases seen for difficulty sleeping; chest pain or tightness; shortness of breath; cold or flu symptoms; and nausea, vomiting, or diarrhea

Offspring of mothers with ideal CV health live nine more years free from CVD than offspring of mothers with poor CV health

Reduction in HbA1c at 104 weeks greater with exenatide plus dapagliflozin versus either drug alone

More than 38,000 campus cases have been reported in the past two weeks

Mortality reduced for patients with newly diagnosed breast, colorectal, lung cancers, mediated by earlier stage of diagnosis

Sixteen percent of COVID-19 cases may only present with gastrointestinal symptoms, which include nausea, vomiting, diarrhea