Levels of Burnout High for Emergency Medicine Health Care Providers

Only 41 percent of responders to a survey on burnout reported having access to support programs

Inability to Afford Prescription Meds, Specialty Care More Likely for Adults With Epilepsy

Those with active or inactive epilepsy are also more likely to have Medicaid and other public insurance

Early Brain MRI Phenotypes of Autism Tied to Familial ASD Traits

Greater levels of proband ASD traits correlated with distinctive brain MRI findings in younger siblings who later develop ASD

Appearance of Ovarian Lesions on Ultrasound May Predict Malignancy

For classic lesions, malignancy rate was <1 percent compared with 32 percent for nonclassic lesions with blood flow

Proportion of Asymptomatic SARS-CoV-2 Infections Unclear

Most SARS-CoV-2 infections are not asymptomatic; those with asymptomatic infections are less infectious

Airway Injuries Severe Consequence of Button Battery Ingestion

Tracheoesophageal fistulae and vocal cord paralyses are most common airway sequelae; vocal cord paralysis occurs after shorter exposure

Retinal Layer Thickness Linked to Cognitive Decline in Older Adults

Thinner baseline total macular retinal nerve fiber layer thickness associated with larger decline in cognitive function test scores during follow-up

Metformin, Lifestyle Changes Cut Risk for T2DM, But Not CVD

No reduction seen in first occurrence of nonfatal MI, stroke, or CV death with either metformin or lifestyle intervention versus placebo

Drug Therapy for Peds Psych Disorders, Later SUD Risk Examined

Majority of studies showed reduced risk for developing substance use disorder with pharmacotherapy for childhood-onset psychiatric disorders

Exposure to Air Pollution Linked to Severe SARS-CoV-2 Outcomes

Odds ratios increased for hospital admission, ICU admission, death with increased exposure to increased ground-level ozone

Healthy Lifestyle May Lower Dementia Risk Despite Genetics

Higher scores in Life's Simple 7 at midlife linked to lower risk for dementia across the range of genetic risk

Seizure-Related Emergency Visits Dropped in Early Pandemic Period

Seizure-related visits increased to almost prepandemic levels for all age groups by end of 2020, except among those aged 0 to 9 years

Exposure to Air Pollution May Increase In-Hospital Stroke-Related Deaths

Each 10 µg/m3 increase in short-term, long-term average exposure to PM1, PM2.5, PM10 linked to increased risk for in-hospital fatality

Inappropriate Outpatient Antibiotic Rx Common for Children

Inappropriate prescriptions linked to increased risk for adverse drug events, increased health care expenditures

AI Aids Assessment of Indeterminate Pulmonary Nodules on CT

Improvement seen in risk stratification and management recommendations with use of computer-aided diagnosis

Beliefs Associated With Sunscreen Use Identified for Over 50s

Odds of using sunscreen increased for those who believe it will prevent sunburn, those whose romantic partners think they should

DDW: Cannabinoid Use Ups Sedation Requirements During Endoscopy

However, patients with cannabis use do not have increased awareness or discomfort during procedures

More Shipments of Baby Formula Heading to Store Shelves Soon

Abbott Nutrition leadership apologized on Wednesday for the company's role in a nationwide shortage of infant formula

Point-of-Care Lung Ultrasound Feasible for Pneumonia Diagnosis in Primary Care

Short training program appears sufficient and little time is needed to perform the scan in practice

Prognostic Model Predicts Survival in Elderly With GI Diffuse Large B-Cell Lymphoma

Model including four clinical factors can predict overall survival, with predictive performance superior to Ann Arbor staging system

Breastfeeding Duration Has Modest Effect on Child’s Cognition

Effect remains when adjusting for socioeconomic factors, maternal cognition

Monkeypox Poses Challenges, Even in High-Income Countries

Three of seven patients in U.K. were treated with brincidofovir; all developed elevated liver enzyme resulting in cessation of therapy

Survey IDs Challenges of Health Care Environmental Hygiene

50 of 51 health care facilities surveyed lacking in some or all of the five components of the WHO multimodal hand hygiene strategy

Eldecalcitol Does Not Prevent Type 2 Diabetes in At-Risk

Eldecalcitol may have beneficial effect among those with lower level of basal insulin secretion

Several Health Indicators Differ for LBG, Heterosexual Adults

Bisexual men and women, gay men, lesbian women reported smoking, heavy drinking, using marijuana, illicit stimulants more often

Operating Overnight Not Tied to Worse Outcomes for Next-Day Surgeries

Incidence of in-hospital death, major complications similar when the attending surgeon operated the night before

Extreme Heat Tied to Higher All-Cause Mortality

Greater increases seen among older adults, men, and Black populations

Melatonin Aids Sleep in Older Adults

A 5-mg dose of melatonin can improve sleep in both the biological daytime and nighttime

Model Targeting Appetitive Traits Aids Weight Loss

Individuals who score higher on food responsiveness lose more weight in the responsiveness to cues interventions

Recognition of Fear, Anger Impaired in Psychosis Patients

Facial anger recognition was significantly associated with schizophrenia polygenic risk score

Post-COVID Conditions Are Common Among Adult Survivors

More than twofold risk of acute pulmonary embolism and respiratory signs and symptoms among survivors aged 18 to 64, ≥65 years

Abbott to Re-Open Baby Formula Plant on June 4

FDA is also talking with foreign formula manufacturers and suppliers about bringing their products to the United States

FDA Approves First Treatment for Eosinophilic Esophagitis

The monoclonal antibody showed significantly reduced eosinophils in the esophagus and patient-reported symptoms scores

Suicide by Firearm Down Globally From 1990 to 2019

However, rates showed great variation by country, with the highest rates seen in Greenland and the United States

Gout Drug May Cut Mortality in Heart Failure Hospitalizations

In-hospital mortality rate lower for patients with acute heart failure exacerbation who received colchicine for gout flare

Impact of Policy Changes for Anemia Care in Hemodialysis Examined

Changes in anemia care associated with lower risks for major adverse cardiovascular events, stroke, mortality, heart failure

Alzheimer Disease in Down Syndrome Similar to Autosomal Dominant Form

Age at onset, mortality for Alzheimer disease in people with Down syndrome comparable with fully penetrant form of the disease

Rheumatology Practice at or Above Prepandemic Levels

Financial health of community rheumatology practices and patient referrals same or better, while telemedicine visits remain part of practice

Infertility Tied to Male Breast Cancer Risk

Breast cancer risk linked to male-origin infertility; risk also up for men who have not fathered any children

H. pylori Infection Often Detected in Patients With Dyspepsia

Study in Ethiopia shows risk factors for peptic ulcer disease include H. pylori infection and NSAID/acetylsalicylic acid use

Number of Births, Fertility Rate Increased in 2021

Increases of 1 percent seen from 2020 in provisional number of births, general fertility rate; marks first increase since 2014

COVID-19 Can ‘Rebound’ After Treatment With Paxlovid, CDC Says

In these cases, the illness improved or resolved within an average of three days

Tech With Peer Support, Clinical Triage Feasible for Psychosis

Intervention including app for active monitoring of early warning signs is feasible and linked to lower fear of relapse

Strategies for Addressing Shortage of Iohexol Discussed

Immediate response should include establishment of institution-wide committee to create plans for contrast conservation

USPSTF: Evidence Lacking for Glaucoma Screening in Adults

And in second recommendation statement, evidence insufficient for screening asymptomatic older adults for impaired visual acuity

Cochlear Implants Beneficial for Deafness, Developmental Delays

Gains in cognitive skills, adaptive function slower for children with low cognition, low adaptive behavior with hearing aids versus implants

Lidocaine Infusions Beneficial for Refractory Chronic Migraine

Decrease seen in median pain rating from baseline to end of hospitalization; pain rating remained below baseline at postdischarge visit

E-Cigarette Use Tied to Excess Health Care Utilization

Current use contributed to $15.1 billion in annual health care expenditures in 2018

Counseling, Provision Interventions Increase Contraceptive Use

No increased risk seen for sexually transmitted infections or reduction in condom use with interventions

Cranberry Supplements May Aid Memory in Older Adults

Improvement in neural functioning also seen during 12-week intervention

Risk for Hospitalization for Heart Failure Down With SGLT-2i Treatment for T2D

Risk for stroke, MI, all-cause mortality similar for those initiating SGLT-2i or metformin

Burden of Persistent Symptoms High After COVID-19 Infection

No specific causes of symptoms of postacute sequelae of SARS-CoV-2 infection identified

Persistent Opioid Use After Sarcoma Treatment Explored Among Youth

23 percent of adolescents and young adults who used opioids during treatment have new persistent use after treatment

Risk for VTE Up During Five Years After Prostate Cancer Diagnosis

Incidence proportion ratios decreased from 2.53 at six months to 1.59 at five years of follow-up

Formal Training in Cardio-Obstetrics Uncommon

Only 29 percent of practicing cardiologists reported receipt of cardio-obstetrics didactics during training

Antibody Levels After COVID-19 Vaccination Inversely Linked to Body Weight

Inverse correlation sustained for up to six months following two doses of BNT162b2 in small cohort of healthy young and middle-aged adults

Three-Dose Pfizer Vaccine Spurs Strong Response in Youngest Children

Company says third dose gave the young children 80 percent protection against asymptomatic COVID-19

Survival Similar for Early, Delayed Surgery in Stage I Esophageal Cancer

For patients with stage II/III esophageal cancer, five-year survival is improved with early versus delayed esophagectomy

Emergency Shipment of Baby Formula Arrives From Europe

Formula is designated for infants intolerant of the protein supplied by cow's milk

Vaccination After SARS-CoV-2 Infection May Cut Long COVID Risk

Initial decrease in odds for long COVID seen after first vaccine dose with evidence suggesting sustained improvement after second dose

Nearly Four in 10 Older Women Remain Sexually Active

Authors say women should speak to their providers about sexual health, including the impact of menopause-related symptoms

Jif Peanut Butter Recalled Due to Possible Salmonella

Fourteen illnesses (including two hospitalizations) tied to infection; no deaths have been reported

Comorbidities Explored in Palmoplantar Pustulosis

Patients with PPP have significantly higher risk for ankylosing spondylitis, Graves disease than those with psoriasis vulgaris

Pediatric Mental Health Crises Up During First Year of Pandemic

Average length of boarding increased more than twofold; about half of patients experienced extended boarding of two or more days

Odds of COVID-19 Mortality Lower for Women Receiving HRT

Receiving hormone replacement therapy within six months of recorded COVID-19 diagnosis linked to reduction in mortality

Drug Therapy for AUD May Cut Risk for Alcohol-Related Liver Disease

Pharmacotherapy for alcohol use disorder linked to reduced incidence of hepatic decompensation in patients with cirrhosis

Gabapentin May Cut Opioid Needs for Oral Mucositis Pain During RT

Findings seen in studies involving patients receiving chemoradiotherapy for nonmetastatic squamous cell carcinoma of head and neck

Physicians Often Experience Mistreatment, Discrimination

Experience of mistreatment or discrimination by patients, families, visitors independently linked with higher odds of burnout

Global Burden of RSV Profiled in Children Aged 0 to 60 Months in 2019

In 2019, 2.0 and 3.6 percent of deaths in children aged 0 to 60 months and 28 days to 6 months, respectively, attributable to RSV infection

Early Intervention May Be Better for Severe Asymptomatic Aortic Stenosis

Risks for all-cause mortality and hospitalization for heart failure reduced according to meta-analysis of data from two randomized trials

Tezepelumab Effective for Severe, Uncontrolled Asthma

Nearly half of patients experience a complete response to treatment across multiple measures

Follow-Up Often Delayed After High-Risk Findings on Lung Cancer Screening

Patients with more severe findings less likely to have prolonged delays; current smokers had more delays than former smokers

Candidate Biomarkers Identified for Psoriasis Progression

Genomic, proteomic, and metabolomic biomarkers identified from systematic review of relevant studies

Closed Baby Formula Plant May Reopen by Next Week

Earlier this week, the FDA announced a preliminary deal with Abbott to restart production if safety upgrades and certifications are met

Mystery of Pediatric Hepatitis Cases Deepens as CDC Probe Continues

One more U.S. death related to pediatric hepatitis was reported on Thursday

Mounjaro Approved for Blood Glucose Control in Type 2 Diabetes

The once-weekly injection is approved as an addition to diet and exercise

Senate OKs Bill to Overhaul Infant Formula Rules

In addition, the DoD is hiring commercial aircraft to transport Nestlé formula from Switzerland to the United States

1999 to 2019 Saw Decrease in Cancer Mortality for Blacks in the U.S.

However, in 2019, Black men and women had highest cancer death rates compared with other racial, ethnic groups

Regulatory, Patent Reform Needed for Inhalers for Asthma, COPD

Manufacturers have employed various strategies to obtain regulatory exclusivities and patents on inhalers, limiting generic competition

CDC: 64.1 Percent of Violent Deaths in 2019 Were Suicides

Suicide rate was higher for males, among adults aged 45 to 54 years, and for AI/AN and non-Hispanic Whites

CDC Advisers Recommend Pfizer Booster Shot for Children 5 to 11

Third shot can be given at least five months after healthy children complete the two-dose vaccine series

Prevalence of Risk Factors for Alzheimer, Related Dementias Identified

Highest prevalence seen for high blood pressure and not meeting aerobic physical activity guidelines, followed by obesity

Psychological Distress May Increase Risk for COVID-19 Hospitalization

Depression, worry about COVID-19, loneliness as strongly linked to hospitalization as high cholesterol, hypertension

Clinical Support Software May Aid Medication Tasks in the OR

Mean total task time less for those using clinical decision support software prototype versus current standard electronic health record workflow

Pollution Accounts for One in Six Deaths Worldwide

Urgent attention needed to control pollution, including air pollution and pollution from hazardous chemicals, and prevent related disease

Burden of Medical Costs for Sickle Cell Disease Quantified

Over nonelderly lifetime, SCD-attributable costs were estimated at $1.7 million for males; with out-of-pocket costs of $45,091

Prevalence of Past-Month Adolescent Vaping 8.6 Percent Overall

Also, this study of adolescent vaping in 47 countries shows prevalence of past-month frequent vaping relatively low at 1.7 percent

Time-Restricted Eating Reduces CVD Risk for Older Breast Cancer Survivors

15 percent relative reduction in the median Framingham CVD risk following eight weeks of time-restricted eating intervention

Clinical Predictors Could Guide Lithium Dosage in Bipolar Disorder

Model based on six clinical predictors explained 61.4 and 49.8 percent of variance in body clearance of lithium, respectively, in two cohorts

CDC: U.S. Cases of Acute Hepatitis in Children Keep Rising

However, there have been no reported deaths since February, agency says

Age-Specific Dementia Risk Scores Developed for Mid, Late Life

Elevated systolic BP and diabetes mellitus most important vascular risk factors for increased 10-year incident dementia risk at age 55

U.S. Hospitals Facing Shortage of Dye Needed for Life-Saving Scans

Shortage expected to last until at least June 30, according to the American Hospital Association

E-Cigarettes May Be Better Than Nicotine Patches for Pregnant Women

Safety of e-cigarettes in pregnancy is similar to that of nicotine patches while possibly more effective

Biden Invokes Defense Act to Boost Supply of Infant Formula

Federal government can now use commercial aircraft or air cargo planes owned by the DoD to transport infant formula from countries abroad

Rollout of Pfizer COVID-19 Vaccine Saved Lives, Health Care Dollars

Model shows vaccine tied to prevention of 110,000 deaths and a resulting $30.4 billion direct health care cost savings

Massachusetts Man Has Monkeypox, Following Clusters in Europe

Currently, patient is in the hospital and reported to be in good condition

Preexisting Cardiovascular Conditions Tied to Severe COVID-19 in Children

Risk varies considerably across 26 examined cardiovascular conditions

Outcomes of Abdominal Wall Reconstruction Compared by Surgeon Rank

Long-term hernia recurrence rates similar for abdominal wall reconstruction performed by surgical fellows, faculty

More Cases of Monkeypox Emerge in Portugal as Outbreak Widens

Patients in the confirmed cases have skin lesions and are in stable condition

Cosmetic Outcome Comparable With 1-, 2-cm Suture Spacing

No significant difference seen in total mean Patient and Observer Scar Assessment Scale score assessed by patients, observers

Risk for Ectopic Pregnancy Increased for Women With Psoriasis

Ectopic pregnancy is only adverse pregnancy outcome significantly associated with psoriasis

Lifestyle Coaching Intervention Improves BP Control Among Blacks

At 24 and 48 months, greater BP control was seen in the lifestyle coaching group versus the usual care group

Delays in Care Longer for Female Trauma Patients

Female trauma patients had longer stay in ED, longer time in pretriage, increased likelihood of discharge to nursing or long-term care facilities

Supervised Exercise Program Beneficial for Seniors With Hip Fracture

Greater improvement on Instrumental Activities of Daily Living, Short Physical Performance Battery reported with home exercise program

Increased Flexibility Seen in Preapproval Evidence for New Drugs

Twenty-eight percent of trials used historical, external, or other control; nearly half used surrogate measure as a primary end point

Screening Could Help Identify Familial Hypercholesterolemia

For adults aged 20 to 39 years, clinical criteria alone would yield 1.3 cases per 1,000 screened; adding genetic testing would increase the yield to 4.2 cases

Sleep Problems Not a Major Issue in Rheumatoid Arthritis

Existing sleep problems related mainly to disease-related measures, such as pain and reduced function, more so than disease duration

Loss of Smell, Taste Less Likely With Newer COVID-19 Variants

Lower risk for developing chemosensory loss observed with alpha, delta, and omicron variants

Using New Guidelines Would Increase Diabetes Screening Eligibility

Screening eligibility would increase overall and among those with prediabetes with USPSTF 2021, ADA 2022 guidelines

Room for Improving Physical Activity Reported in Early Child Care

Only half of the programs for children aged 1 to 5 years meet the guidance of at least 60 to 90 minutes of physical activity per day

Early Glycemic Control May Cut CV Risk in Type 2 Diabetes

Greater glycemic variability is associated with increased risk for major adverse cardiovascular events

Medicaid Expansion Affected Overall Survival Rates Among Cancer Patients

Medicaid expansion linked to increase in two-year overall survival, with greater increase seen for non-Hispanic Blacks, patients in rural areas

Smokers Who Shift to Vaping May Improve Other Health Measures

Findings seen for adults' health and social functioning measured at ages 30 and 39 years

Albuterol Plus Budesonide Cuts Exacerbations in Asthma

Risk for severe exacerbations significantly lower with as-needed fixed higher-dose combination treatment versus albuterol alone

Rare Cases of Monkeypox Diagnosed in Britain

None of the individuals had traveled to the African countries where the virus is endemic

Breast Cancer Risk Up With Dense Breasts, Benign Breast Disease

Elevated risk also seen for benign breast disease and fatty breasts and extremely dense breasts without benign breast disease

Choroid Plexus Volume Up With Advanced Cognitive Impairment

Larger volume associated with severity of cognitive impairment across Alzheimer disease spectrum

Emphysema Prevalence Higher in Black Adults

Spirometry measures predicted based on race-specific equations may result in underrecognition of lung disease in Black adults, authors say

Guideline Updated for Management of Spontaneous ICH

Some in-hospital therapies and prophylactic treatments may confer no benefit or are potentially harmful and should be reconsidered

Emergency Residents Lacking in Rural Areas of United States

New training programs from 2013 to 2020 were disproportionately added to states with already high number of programs

AUA: Immunotherapy Aids Survival in Muscle-Invasive Bladder Cancer

Patients receiving nivolumab had an approximately 30 percent lower likelihood of developing cancer recurrence versus placebo

Biden Signs Law Banning Sleep Products Tied to Infant Deaths

From 1990 through March 2019, there were 113 reported deaths involving crib bumpers, and more than 100 babies have died in inclined sleepers

Increasing Impact of HPV Vaccination Seen in the United States

Impact on 4vHPV-type prevalence in 2015 to 2018 for 14- to 24-year-old females 90 percent among vaccinated, 74 percent among unvaccinated

Obesity Linked to Increased Risk for Crohn Disease

Obesity, as measured by BMI, linked to increased risk for CD, but no association seen for ulcerative colitis

Newly Certified General Internists Mainly Choose Hospital Practice

Most hospitalists in 2013 had the same practice type five years later; rate of retention similar for early-career, more senior physicians

FDA Authorizes Pfizer Booster Shot for Children Ages 5 to 11 Years

Third shot can be given at least five months after healthy children complete the two-dose vaccine series

AUA: Outcomes of Robotic, Open Cystectomy Compared in Bladder Cancer

Number of days alive and out of hospital within first 90 days greater for robot-assisted surgery, but clinical significance of findings unclear

FDA Expands Baby Formula Market to Foreign Suppliers

Agency also moves to reopen Abbott plant and 'prioritize' new product submissions for approval from international companies

mRNA-1273 Induces Stronger Response Than BNT162b2 for Immunosuppressed

Findings seen in immunosuppressed patients with rheumatic and musculoskeletal diseases, solid organ transplant recipients

Sexual Minority Status Linked to Lower Odds of Pap Screen

Odds of ever undergoing pap testing lower for non-Hispanic White and Hispanic SM participants versus non-Hispanic White heterosexuals

Hypertension, Arterial Stiffness Linked to Risk for Diabetes

Highest risk for diabetes seen for those with hypertension, AS compared with those with normotension and normal AS

Hispanic Patients Wait Longer When Presenting to ED With Chest Pain

Overall disposition from the emergency department was 1.39 times longer for Hispanic versus non-Hispanic patients

Vaccine Effectiveness Modest for Children, Teens During Omicron

BNT162b2 vaccine effectiveness against symptomatic infection modest and declined rapidly, was higher after booster dose in teens

Risk for Type 1 MI Hospitalization Increased With Prediabetes

Younger adults with prediabetes have increased odds of T1MI, but do not have increased risk for MACCE

Prevalence of Multimorbidity Up in Rheumatoid Arthritis

Prevalence of 24 of 44 previously defined morbidities and seven of 78 additional chronic disease categories significantly higher

DDW: Cardiovascular Disease More Common in Lean NAFLD Patients

Findings independent of other risk factors like age, sex, race, smoking status, diabetes, hypertension, and dyslipidemia

Deficits in Geriatric Assessment Prevalent in Seniors With IBD

Clinical and biochemical disease associated with deficits in geriatric assessment

Guideline Updated for Use of Radiation for Brain Metastases

Updated guideline discusses advanced radiation therapy techniques and places emphasis on multidisciplinary care

AUA: Pandemic Disruptions Impacted One in Four Prostate, Bladder Cancer Patients

Changes, delays, and cancellation of cancer treatment and ancillary care reported

One in Nine Discharged After COVID-19 Admission Die or Are Readmitted

Higher risk seen for patients who were male, had multiple comorbidities and more previous emergency department visits

AUA: Kidney Transplants From COVID-19-Infected Donors Are Safe

Recipient outcomes similar to kidneys from noninfected donors

Coronary Heart Disease Risk Higher With COPD

However, emphysema score, lung function, exacerbation frequency, and hypoxemia do not predict coronary stenosis or calcium score >100

Menopause Symptoms Correlate With Temporomandibular Disorder Pain

Correlation stronger in the late menopausal transition than other time points

DDW: Gallstone Disease May Predict Pancreatic Cancer Incidence

Gallstone presentation may be a missed opportunity for earlier diagnosis

DDW: Antibiotics Up Risk of Older-Onset Inflammatory Bowel Disease

Findings regardless of antibiotic class and with a dose-response relationship

AI Applied to Apple Watch ECG Can ID Ejection Fraction ≤40 Percent

Artificial intelligence algorithm applied to watch single-lead ECG identified 13 of 16 patients with left ventricular dysfunction

Long-Term Mortality Rates Elevated for Adolescent, Young Adult Leukemia Survivors

Survival for adolescent and young adult leukemia survivors remained below general population at up to 30 years of follow-up

Cessation Program in Cancer Clinics May Reach More Tobacco Smokers

Low-burden, point-of-care program may increase access to and impact of treatment to assist tobacco cessation

Inflammation During COVID-19 Hospitalization Linked to Mortality

Elevated C-reactive protein during hospitalization associated with increased mortality risk after recovery from COVID-19

Responses to Screening for Suicide Risk May Differ for Gun Owners

When probability of suicide attempt increases, gun owners may be less likely to endorse survey items about passive, active suicidal ideation

50-µg mRNA-1273 Safe, Effective for Children Aged 6 to 11 Years

Estimated vaccine efficacy with two doses was 88.0 percent against COVID-19 at a time when delta was dominant circulating variant

During Pandemic, Growth of Clinicians With X-Waivers for Buprenorphine Prescribing Slowed

Survey of 126 clinicians helps pinpoint barriers to obtaining waivers, prescribing buprenorphine

Persistent Viral Shedding Common in Hospitalized COVID-19 Patients

Persistent viral shedding associated with in-hospital delirium and increased six-month mortality

Slight Increase Reported in Lung Cancer, Brain Tumors With Wildfire Exposure

Individuals exposed to wildfire within 50 km of residential locations in past 10 years had slightly higher incidence

Menopause Tied to Proatherogenic Changes in Circulating Metabolites

Increase seen in concentrations of apoB, very-LDL triglycerides and particles, LDL cholesterol and particles, HDL triglycerides

Intervention Can Cut Risk for Mobility Disability in Seniors

Reduced incidence of mobility disability seen in older adults with physical frailty and sarcopenia receiving multicomponent intervention

DDW: ‘Alarming’ Rise in Esophageal Cancer, Barrett Esophagus Seen in Middle-Age

Number of endoscopies performed not increasing, despite increased prevalence

Cardiometabolic Derangement ID’d in Overweight School Children

Higher levels of fasting glucose, insulin, HOMA-IR, triglycerides, ALT and lower levels of HDL-C seen in overweight school-aged children

Impact of Diet on Gestational Diabetes Risk Unknown in Minority Populations

Significant protective impact of healthy diet only seen among White European women

Rapid Recovery Seen With More Frequent Dialysis in SNFs

Rapid recovery associated with reduced mortality and fewer hospitalizations

Most Patients Have Positive Views About AI in Medicine

However, concern expressed relating to unintended consequences, including misdiagnosis, privacy breaches, less time with clinicians

‘Tragic Milestone’: One Million American Lives Lost to COVID-19

President Biden has ordered U.S. flags to be flown at half-staff in honor of those lost

Self-Reported Postpartum Depressive Symptoms Up During Pandemic

States with greater increases in symptoms had fewer deaths from COVID-19 and lower women's unemployment rates

Buprenorphine Underused for OUD, Particularly Polysubstance Use

Yet, study shows buprenorphine is effective in protecting against overdose in this population

Lenacapavir Reduces Viral Load in Multidrug-Resistant HIV-1 Infection

Reduction in viral load from baseline greater with lenacapavir versus placebo among those with multidrug-resistant HIV-1 infection

Serotonergic Antidepressants in Pregnancy Not Tied to Neonatal Seizures

Maternal use of SSRIs, SNRIs in first trimester of pregnancy not linked to increased risk for neonatal seizures or childhood epilepsy in offspring

Link Between Major Traumatic Brain Injury, Dementia Examined

Risk factors most strongly attenuating the association between major TBI and dementia were alcohol consumption, physical activity

Digital Breas​t Tomosynthesis Tool Can Help Predict Breast Cancer

DBT-based risk model can predict cancer after a negative screening exam, with high discriminative performance for one-year risk

TXA Seems Safe for Surgery in High-Risk Patients With IT Hip Fracture

No increased risk for mortality or thromboembolic complications seen with use of tranexamic acid among high-risk patients, entire cohort

Previous Myocardial Injury Tied to Worse COVID-19 Outcomes

Significant but weaker associations with selected adverse outcomes seen for preexisting hypertension, diabetes, and ischemic heart disease

Number of Mesothelioma Deaths Up Among Women From 1999 to 2020

However, age-adjusted death rate per 1 million women decreased significantly, from 4.83 to 4.15 from 1999 to 2020

2019 to 2020 Saw Increase in Overall Firearm Homicide Rates

Largest increases seen among non-Hispanic Black males aged 10 to 44 years and in American Indian, Alaska Native males aged 25 to 44 years

Health Improves Over Two Years for COVID-19 Hospitalization Survivors

Improvements seen in physical and mental health, but survivors still have more symptoms than controls at two years

Suicidal Ideation Common Among World Trade Center Responders

Depression, functional impairment, alcohol use problems, and lower family support ups risk

CDC: Overdose Deaths Up 15 Percent in 2021

However, growth in overdose deaths has slowed compared with the 30 percent increase seen in 2020

FDA Moves to Ease Nationwide Shortage of Baby Formula

The agency's latest moves should help ease the dire situation many mothers face

EU Scraps Mask Mandate for Planes, Airports

However, masking rules may still vary by airline if regulations are different in the locations they fly to or from

Lack of Asthma Control More Likely With COVID-19-Related Anxiety

Second study shows most parents of children with food allergy report unchanged or decreased food allergy-specific anxiety during pandemic

Ban of Indoor Tanning Beds Would Reduce Cancers, Cut Costs

Intervention would yield net monetary benefit of £10.6 million and net health benefit of 530 QALYs

Espresso Consumption Linked to Increase in Serum Total Cholesterol

Consumption of three to five versus zero cups of espresso linked to increased S-TC in women and men, with greater increase for men

High AI-ECG-AF Risk Score Tied to Worse Cognition, Cognitive Decline

High probability of atrial fibrillation by AI-ECG-AF score correlated with cerebral infarcts on MRI

Subcutaneous Implantable Defibrillators Cut Lead-Related Complications

Risk for major lead-related complications much lower with subcutaneous ICD versus transvenous ICD

Review: Power Training, Strength Training Compared for Older Adults

Modest improvement in physical function with power training versus traditional strength training

Neuropsychiatric Sequelae Similar for Severe COVID-19, SARI

Neuropsychiatric sequelae are comparable for survivors of COVID-19 hospitalization, other severe acute respiratory infections

Early Tracheostomy No Aid for Severe Stroke Outcomes

Findings for six-month functional outcomes among patients with severe stroke receiving mechanical ventilation

One in Three Alzheimer, Dementia Cases Tied to Modifiable Risk Factors

Risk factors differ based on sex and race and ethnicity

Recent Cancer Treatment Linked to Worse COVID-19 Outcomes

However, a history of cancer more than one year before COVID-19 diagnosis not tied to increased mortality or hospitalization

An Hour Less of Sitting Daily Improves Cardiometabolic Measures

Findings for modest increases in light-intensity and moderate-to-vigorous activity among adults with metabolic syndrome

Serious Neurologic Manifestations Tied to Worse COVID-19 Outcomes

Encephalopathy was the most common serious neurologic manifestation, occurring in 10.2 percent of adults hospitalized with COVID-19

Impact of Healthy Lifestyle on GDM Risk Varies With Genetic Risk

Lifestyle intervention effective in reducing age-adjusted occurrence of GDM only among those with the highest genetic risk for type 2 diabetes

Rare Cases of COVID-19 Relapse Seen With Pfizer Pill

Reports of symptoms returning in patients several days after completing the five-day regimen of Paxlovid

Heterogeneity in CV Mortality Seen in Asian American Subgroups

Several subgroups experiencing stagnant age-standardized mortality rates for cardiovascular, cerebrovascular mortality

Company Hid Problems With COVID-19 Vaccines From FDA

Nearly 400 million doses of vaccine made by Emergent had to be destroyed 'due to poor quality control'

PFAS, Phthalate Biomarkers Linked to Bone Mineral Density in Teens

Each doubling of serum perfluorooctanoate, overall PFAS/phthalate mixture linked to lower areal BMD in male adolescents

Subsidized Supermarkets May Cut Obesity Risk in Children

Findings for underserved students living within 0.50 miles of a subsidized supermarket

Normal-Looking Skin Involved in Cutaneous Lupus Erythematosus

Normal-appearing skin is type I interferon-rich environment; interferon-induced gene expression changes seen in all major skin type cells

NIH Launches Clinical Trial of Epstein-Barr Virus Vaccine

The phase 1 trial is expected to last four years and enroll 40 participants

Recommendations Updated for Idiopathic Pulmonary Fibrosis

Guideline updates prior IPF guidelines and addresses progression of pulmonary fibrosis in interstitial lung diseases other than IPF