Fauci Calls for Americans to Pull Together, Says ‘Help Is on the Way’

Anthony Fauci, M.D., spoke with HD Live! about the safety and efficacy of a COVID-19 vaccine and doubling down on efforts to stop the surge in cases

2016 to 2019 Saw Increase in Prepregnancy Obesity in U.S.

Increase seen across women of all ages, Hispanic origin groups, educational levels

USPSTF Urges Behavioral Counseling to Reduce CVD Risk

Behavioral counseling interventions to promote healthy diet and physical activity have moderate net benefit

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Predictors of Satisfaction With RYGB Over Seven Years Identified

And, physical activity associated with improvements in depression and mental and physical HRQoL after RYGB

RSNA: Anxiety May Hasten Progression to Alzheimer Disease

Rate of progression from MCI to AD increased with ApoE4, anxiety, lower hippocampal and entorhinal cortex volumes

AI Algorithm Can Detect COVID-19 on Chest X-Rays

Accuracy of 82 percent achieved with DeepCOVID-XR compared with 81 percent for consensus of five thoracic radiologists

U.S. COVID-19 Vaccine Distribution Could Begin in Mid-December

Vaccine appears 95 percent effective at preventing mild-to-severe COVID-19, according to the manufacturers

Delirium Common in Seniors Presenting to ED With COVID-19

Delirium is the sixth most common presenting symptom/sign; delirium linked to ICU stay and death

Purdue Pharma Pleads Guilty Over Role in U.S. Opioid Epidemic

Company admits paying doctors to write more prescriptions, providing misleading information to the DEA

Hormonal Contraceptives Linked to Decline in Asthma Exacerbation

Risk reduced with previous and current use of any and combined hormonal contraceptives, not with progestogen-only use

Job Changes Increasingly Common Among U.S. Radiologists

Practice separation most common among early- and late-career radiologists, general radiologists

AHA: Ablation Better Than Meds for Initial A-Fib Treatment

Findings based on randomized trial evaluating initial treatment with cryoballoon catheter ablation versus standard meds

AHA: Sotagliflozin Beneficial for T2DM With Heart Failure

Second study shows benefits among patients with type 2 diabetes and chronic kidney disease, risks for CVD

Many Infants With Hep C-Positive Moms Not Screened for HCV

Prenatal care is an important time to screen for hepatitis C, authors say

Xofluza Approved for Postexposure Prevention of Flu

Influenza infection and symptoms occurred in 1 and 13 percent of those receiving Xofluza and placebo, respectively

CDC Recommends Three COVID-19 Tests for Americans Traveling Abroad

Tests recommended one to three days before the flight, three to five days after the flight, and one to three days before returning

Mediterranean Diet Cuts Type 2 Diabetes Risk in Women

Risk reduction driven by improvement in insulin resistance, lipoprotein metabolism, and inflammation

First Drug Approved to Treat Rare Metabolic Disorder

Oxlumo granted approval to treat primary hyperoxaluria type 1

CDC Warns That COVID-19 Vaccine Might Spur Transient Sickness

Some volunteers in trials of candidate vaccines have reported flu-like symptoms after immunization

SARS-CoV-2 Infection Rates Generally Low in U.S. Children

Black, Hispanic, Asian children less likely to get tested for SARS-CoV-2, more likely to test positive than White children

RSNA: Neurologic Complications of COVID-19 Examined

In patients with critical findings identified on neuroimaging, most common comorbidities were hypertension, diabetes

BCG Vaccination Linked to Lower SARS-CoV-2 Seroprevalence

Seroprevalence of anti-SARS-CoV-2 IgG lower for health care workers with history of BCG vaccination

COVID-19 Infection Not Tied to Adverse Pregnancy Outcomes

7 percent of mothers delivering at large county health system tested positive, as did 3 percent of tested infants

AHA: Obese Patients More Likely to Be Hospitalized for COVID-19

Risk for in-hospital death, mechanical ventilation higher for obese patients; link between BMI and outcomes strongest for adults ≥50 years

AHA: Out-of-Hospital Cardiac Arrest Outcomes Worse During COVID-19

OHCA outcomes worse early in the pandemic even in areas with low case-fatality rates

ATS Issues Guideline on Home Oxygen Therapy for COPD, ILD

Long-term oxygen therapy strongly recommended for adults with COPD, ILD who have severe chronic resting hypoxemia

Rural, Urban Disparities Seen for New Liver Cancer Cases

New hepatocellular carcinoma cases highest among rural Hispanic residents

Non-COVID-19-Related Deaths Up, Too

Excess deaths seen for specific gender and age groups, with protective effect seen for female children

Contraceptive Use Low Among Women With Kidney Disease

Overall rate of contraceptive use 5.3 percent of person-years

FDA Authorizes Use of Monoclonal Antibody Treatment for COVID-19

IV infusion of casirivimab and imdevimab authorized for treatment of mild-to-moderate COVID-19

Chimpanzee Adenovirus COVID-19 Vaccine Promising in Seniors

Immunogenicity similar across age groups; vaccine better tolerated in older versus younger adults

WHO: Remdesivir Not Advised for Hospitalized COVID-19 Patients

Evidence to date has not shown clinically important effects on mortality, need for mechanical ventilation

Third COVID-19 Vaccine Shows Effectiveness

The AstraZeneca vaccine becomes the third to show good effectiveness

AHA: Blacks, Hispanics Make Up 53 Percent of COVID-19 Deaths

Mortality, MACE rates among patients hospitalized with COVID-19 did not differ by race, ethnicity

Cirrhosis Cases Rising Among Women in North America

Projected future increases in cirrhosis due to alcohol-related liver disease and nonalcoholic fatty liver disease

Early ECMO-Facilitated Resuscitation Ups Survival in OHCA

Findings seen among adults with out-of-hospital cardiac arrest and refractory ventricular fibrillation

AHA: Care for Type 2 Myocardial Infarction Patients Varies

Just over half of patients with type 2 MI seen by a cardiologist in hospital; most did not see a cardiologist for follow-up care

Cognitive Exercises May Lower Risk for Postoperative Delirium

Cognitive prehabilitation reduced delirium among older adults undergoing major noncardiac surgery

FDA-Authorized Alpha-Defensin Lateral Flow Test Highly Accurate

Test demonstrates good performance for rapid diagnosis of periprosthetic joint infection around joint implants

Predictors of Late Effects in Young AML Survivors Explored

Most common late effects were endocrine, cardiovascular, respiratory; likelihood of late effects up for those who underwent HSCT

Vegans Have Increased Risk for Total, Main-Site Fractures

Association attenuated slightly with adjustment for dietary calcium and/or protein but still significant

Social Needs Linked to Lower HRQOL for Black Cancer Survivors

More than one-third of cancer survivors reported social needs, with highest prevalence for food insecurity

AHA Meeting Addresses Latest Research, COVID-19, Health Care Disparities

American Heart Association President-Elect Donald Lloyd-Jones, M.D., discussed highlights of the AHA Scientific Sessions 2020 with HD Live!

Less Than One in 20 Eligible Adults Receives Lung Cancer Screening

Lung cancer screening at the state level does not correlate with lung cancer burden

U.S. Nephrology Trainees Doubt Skill in Home Hemodialysis

Most respondents report being moderately confident about principles of peritoneal dialysis, but few had initiated urgent-start PD

FDA Issues EUA to Baricitinib Plus Remdesivir for COVID-19

Emergency use authorization applies to hospitalized patients requiring supplemental oxygen, mechanical ventilation, ECMO

ALA: Lung Cancer Survival Has Increased Nationally to 22.6 Percent

People of color face worse outcomes, have lower likelihood of being diagnosed early, receiving surgery

High-Dose Anticoagulation May Not Aid COVID-19 Patients

No significant benefit seen for high-dose versus standard anticoagulation therapies, may be harmful

Behavioral, Psych Condition Care Shifted to Telemedicine During COVID-19

Office-based visits decreased from before 2020 to during pandemic, but telemedicine visits increased in 2020 Q1, Q2

Biopsy Reclassification Risk in Prostate Cancer Examined

Gleason grade, prostate-specific antigen velocity, and imaging markers predict cancer spread

Risk for Infection Up for Children Born by C-Section

Increased risk for serious childhood infection following elective, emergency cesarean section persisted to five years

Rates of VTE, Major Bleeding High in Primary CNS Lymphoma

Pulmonary embolism and major bleeding linked to increased mortality risk

Air Pollution May Up Alzheimer Disease Risk in Elderly

Association seen in older women persisted even at PM2.5 levels below U.S. regulatory standards

Preoperative Mental State Associated With Postoperative Pain

Presurgery depression, anxiety, catastrophizing tied to more pain after joint replacement surgery

Greater Social Support Tied to Lower Diabetes-Related Distress

Specifically, perceived support of family members significantly tied to less distress among low-income patients

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

CDC: About One in Five U.S. Adults Reports Tobacco Product Use

Prevalence of any current tobacco product use up for men; adults aged ≤65 years; lesbian, gay, bisexual adults

Teens Increasingly Worried About Their Weight

Large U.K. study shows more teens are dieting, overestimating their weight

COVID-19-Related Job Insecurity Tied to Anxiety, Depression

Survey of nearly 5,000 young adults reveals link between job insecurity and self-reported anxiety, depression

Wrong-Patient Order Entry Errors Reduced With Patient Photos

Display of patient photographs in electronic health records associated with decrease in WPOE errors

TAVR Volumes in the U.S. Have Risen Each Year Since 2011

In 2019, TAVR exceeded surgical procedures; 30-day mortality and stroke rates decreased since 2011

AHA: Adding Omega-3 Fatty Acids Does Not Cut High CV Risk

No reduction seen in CV events with omega-3 versus corn oil in addition to usual background therapies, including statins

Medicaid Expansion Tied to Increased Detection of Early Cancers

Three years after expansion, a decrease in late-stage cancers was also detectable

U.S. COVID-19 Deaths Top a Quarter Million

COVID-19 cases on the rise in all but one state

Disproportionality Signal Found for Suicidality in Finasteride Users

Younger patients and those with alopecia have significant disproportionality signals for increased suicidality

Group-Based Lifestyle Intervention Cuts Progression to T2DM

High-risk individuals making modest changes in weight, physical activity had lower odds of progressing to type 2 diabetes

2009 to 2018 Saw Increase in Incidence of NAFLD in Children

12.3 percent of obese and overweight children with alanine aminotransferase >30 U/L received further workup for NAFLD

Lorlatinib Superior to Crizotinib for ALK-Positive NSCLC

Interim analysis shows risk for disease progression or death lower for first-line therapy with lorlatinib versus crizotinib

Hearing Test Response May ID Newborns at Risk for Autism

Prolonged auditory brainstem response phase, V-negative latency seen in newborns with autism spectrum disorder

2010 to 2018 Saw Decrease in Rate of Death for People With HIV

48.4 percent decrease found in HIV-related death rates and 8.6 percent decrease seen in non-HIV-related death rate

AI Model May Predict Immunotherapy Response in Melanoma

Histology slides, clinical data used to predict immune checkpoint inhibitor response in advanced melanoma

Predictors of Severe Disease ID’d in Children With SARS-CoV-2

Obesity and hypoxia on admission predictive of severe respiratory disease; children with MIS-C more likely to be non-Hispanic Black

Highest Maternal Mortality Rate Seen in United States

United States is only country not to guarantee access to provider home visits or paid parental leave in postpartum period

Vitamin D Supplementation Tied to Reduction in Advanced Cancer

On stratification by BMI, significant reduction found in incident metastatic or fatal cancer in normal weight, not overweight/obese

Fluvoxamine Linked to Reduction in Clinical Deterioration in COVID-19

Findings seen among adult outpatients with SARS-CoV-2 with oxygen saturation of 92 percent or greater

Ebola Outbreak in Democratic Republic of the Congo Declared Over

Wednesday marks 42 days, or two incubation periods, since the last survivor tested negative for the virus

AAP Urges Inclusion of Children in SARS-CoV-2 Vaccine Trials

AAP joins six other medical groups in letter requesting transparency and communication to improve confidence in a vaccine

Hormonal Contraceptive Use May Delay Return of Fecundability

Longest delay of five to eight months found for users of injectable contraceptives; no lasting effect seen on fecundability for long-term use

Permanent Night Shift Workers at Higher Risk for Asthma

Increase in risk for moderate-severe asthma observed in morning chronotypes working irregular shifts, including nights

Genetics Tied to Thromboembolism Risk With Inflammatory Bowel Disease

Genetic signature tied to doubled risk for developing potentially fatal blood clots in one in seven IBD patients

Triplet Therapy Slows Refractory Multiple Myeloma

Progression-free survival longer with once-weekly selinexor-containing regimen versus standard bortezomib and dexamethasone

FDA Approves First Rapid COVID-19 Test for Home Use

Simple nasal swab test requires prescription; people younger than 14 cannot perform the test on themselves

AHA: Polypill, With or Without Aspirin, Reduces Cardiovascular Events

Significant reductions seen in primary outcome for use of polypill and polypill plus aspirin combination

Guidelines Developed for Diabetes Management in CKD

Recommendations and practice points relate to comprehensive care needs, glycemic monitoring, lifestyle interventions

Periodontal Pathogens Linked to Atherosclerosis in RA

Immunoreactivity to Aggregatibacter actinomycetemcomitans serotype b, Aa leukotoxin A linked to atherosclerosis

Final Diagnosis Often Differs From Referral Diagnosis for EIS

In 54 percent of children with exercise-induced respiratory symptoms, final diagnosis differed from referral diagnosis

Air Pollution May Affect Mood, Memory in Oldest-Old Women

Indirect effect of remote NO2 and PM2.5 exposure on declines in episodic memory mediated by depressive symptoms

Pandemic Affecting Young People’s Mental Health

Self-reported symptoms of depression, thoughts of suicide much higher than historical norms

Lack of Insurance Tied to Non-Rx Hormone Use in Transgender Adults

Authors say insurance barrier poses risks to safety, health, and well-being

Sixty-Day Outcomes Examined for Hospitalized COVID-19 Patients

29.2 percent died during hospitalization or within 60 days of discharge; ongoing morbidity was common

Persistent Fatigue Prevalent After COVID-19 Infection

More than half of those recovered from acute phase of COVID-19 experience postviral fatigue, independent of COVID-19 severity

2009 to 2018 Saw Increase in Diseases-of-Despair Diagnoses

Increase in alcohol/substance-related diagnoses largest for those aged 55 to 74 years; increase in suicide-related diagnoses largest for under-18s

ACR: Osteoporosis Underdiagnosed, Undertreated in Older Men

Only 2.1 percent of those with qualifying fractures were diagnosed and treated

Routine COVID-19 Testing Improves Safety of Elective Surgery

Benefits of nasal swab testing seen in high-transmission areas and before major surgery

Hospital Mortality Higher for Critically Ill With COVID-19 Versus Flu

Patients with COVID-19 have slower improvement in oxygenation, longer duration of mechanical ventilation, lower rates of extubation

Sedentary Time Increases With Retirement

Abrupt increase in sedentary time seen for women, with more gradual increase for men

Food Insecurity Tied to Higher Cardiovascular Mortality

Findings independent of changes in demographic, economic, and health care access

Major U.S. Medical Groups Urge Trump to Work With Biden on Fighting COVID-19

In letter from three medical associations, the president is urged 'to share critical data and information as soon as possible'

Laparoscopic Resection May Be An Option for CRC Liver Metastases

For resectable colorectal liver metastases, five-year survival rates similar with laparoscopic, open surgery

Antibiotic Therapy Before Age 2 May Affect Child Health

Risk for childhood onset of health conditions increased for those with early-life antibiotic exposure

Nebulized Interferon Beta-1a Promising for COVID-19

Adults hospitalized for COVID-19 receiving SNG001 versus placebo more likely to show clinical improvement

Female Hormone Rx Not Tied to Retinal Vascular Occlusion

No increase seen in risk for occlusion of retinal artery, vein among women filling prescription for female hormone therapy

Asthma EMS Dispatch Rate Down With Insurance Expansion

Asthma EMS dispatch rate in New York City decreased after implementation of the Affordable Care Act

ACR: Warfarin Tied to Increased Risk for Knee, Hip Replacement in OA

Among adults with atrial fibrillation, warfarin use linked to increased odds of knee, hip replacement versus direct oral anticoagulants

AHA: Black Patients Less Likely to Receive Indicated BP Treatment Intensification

This accounts for about a quarter of the total effect on blood pressure control

MI, ASCVD Risk Higher in Older Adults With Elevated LDL-C

And LDL cholesterol-lowering therapies are effective for reducing cardiovascular events in older adults

Diagnostic Radiation May Up Risk for Testicular Cancer

Testicular germ cell tumor risk elevated with exposure to X-ray and CT below the waist, GI series or barium enema

AKI Common in U.S. Veterans Hospitalized With COVID-19

AKI associated with increased odds of mechanical ventilation use, longer hospital stay, increased risk for death

OCD Symptoms Worsening Among Children During COVID-19

Worsening was most pronounced among children with early age of onset, family history of ADHD

Patients Happier With Doctors of Same Race

Authors say findings point to importance of having a diverse physician workforce

Loneliness Tied to Depression in Adults Older Than 50 Years

Between 11 and 18 percent of depression cases could potentially be prevented by eliminating loneliness

SARS-CoV-2 Transmitted Despite Quarantine Conditions

Among Marine Corps recruits, about 2 percent who were negative for SARS-CoV-2 at start of supervised quarantine tested positive by day 14

Pfizer COVID-19 Vaccine Could Cut Transmission by Half: Company Executive

Manufacturers say vaccine is 90 percent effective in protecting people from the new coronavirus

Moderna Vaccine Shows 94.5 Percent Effectiveness Against COVID-19

Company expects to have about 20 million doses of the vaccine ready to ship in the U.S. by the end of the year

Risk for Heart Failure Lower With Healthy Sleep Patterns

Hazard ratio 0.58 for heart failure with healthy sleep score of 5 versus score of 0 or 1

Lung Cancer Tied to Most Potential Years of Life Lost

Potential years of life lost per death highest for deaths due to cancers of testis, bones/joints, other endocrine sites

Interventions to Increase HPV Vaccine Coverage Cost-Effective

Interventions could avert 3,000 to 14,000 future HPV cancers scaling to the U.S. population

ACR Previews New Pharmacotherapy Guidelines for RA

The 2020 Guideline for the Management of Rheumatoid Arthritis updates guidance on drug treatments

Asymptomatic Brain Bleeds in Newborns Not Tied to Long-Term Harm

Normal brain development and neurodevelopmental scores seen at age 2 years

Positive BRCA Test Results Down From 2008 to 2018

Socioeconomic and regional disparities persist in the use of BRCA testing

Mental Health ED Visits in Children Up Mid-March to October 2020

Proportion of mental health-related ED visits increased 24 and 31 percent for children, adolescents

CDC: 26.4 Percent of U.S. Adults With Diabetes Meet ABCS Goals

About one in four meet combined goals of management of blood glucose, BP, non-HDL-C, avoiding smoking

ACR: Corticosteroid Injections Do Not Speed Progression of Knee OA

Rates of radiographic progression similar for corticosteroid injections, hyaluronic acid injections in multivariable analysis

Antipsychotic Use Declined in Young Children From 2009 to 2017

While there was a shift toward evidence-based indications, majority of use remains off-label

Statins Tied to Lower In-Hospital COVID-19 Mortality Risk

For adults hospitalized in Spain with COVID-19, treatment with statins associated with lower COVID-19-related mortality

Breastfeeding Linked to Fewer Behavioral Difficulties for Children

Fewer parent-reported behavioral problems observed with longer duration of breastfeeding

Targeted Efforts Do Not Alter Outcomes in Healthy Elderly

For seniors, vitamin D, omega-3 supplement, strength training, alone or in combination, do not improve clinical outcomes

Outcomes Vary for Depression Collaborative Care Programs

Programs receiving intensive implementation support more likely to achieve good depression outcomes

Teen E-Cigarette Use Ups Odds of Smoking Cigarettes

Findings seen among teens with no previous intention to smoke conventional cigarettes

Many Certified Cosmetic Surgeons Not Trained in Surgical Discipline

More than six in 10 board-certified cosmetic surgeons advertise procedures beyond the scope of their residency training

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Measles Cases Reach Highest Number in 23 Years

After steady decline in 2010 to 2016, measles cases increased in all WHO regions from 2017 to 2019; deaths increased 50 percent

ACR: Incidence of COVID-19 Low in Patients With Rheumatic Disease

73 percent of those with SARS-CoV-2 infection not hospitalized; 11 percent of those hospitalized required ICU admission

Symptoms Evolve During Five Years After Combat Concussion

Combat-related concussion groups show clinically significant decline from one- to five-year evaluation

AHA: 2007 to 2018 Saw Increase in Prepregnancy Hypertension

Rates of prepregnancy hypertension per 1,000 live births increased from 13.7 to 23.7 among rural women, from 10.5 to 20.0 among urban women

AHA: Mavacamten May Treat Hypertrophic Cardiomyopathy

Improvements in cardiac structure, function seen at 30 weeks of treatment with mavacamten versus placebo

Benefit of E-Cigarettes for Quitting Smoking Unclear

Nicotine e-cigarettes added to counseling improved abstinence at 12 weeks, but not at 24 weeks

Automated Alarm IDs Inpatients at Risk for Sudden Decline

Automated detection of impending clinical deterioration linked to lower mortality within 30 days after an alert

Risks of Opioids Should Be Recognized for Children After Surgery

Opioid prescribing guidelines for children developed; authors underscore importance of nonopioid analgesic options, providing education to patients and their families

U.S. Nursing Homes Seeing Increase in New COVID-19 Cases

New weekly cases in nursing homes up by 44 percent between mid-September and week of Oct. 18

9 Percent Readmitted After Index COVID-19 Hospitalization

Odds of hospital readmission increased with age, presence of chronic conditions, hospitalization within previous three months

AHA: Patient CPR Outcomes Similar With COVID-19 Precautions

No negative impact on survival found with additional safety precautions for health care personnel during COVID-19

HTN Visits Vary for Adults Living in Urban, Rural Residences

Higher proportion of physician visits included hypertension for adults living in rural, small-medium metro areas

COVID-19 at Forefront of IDWeek Discussions

IDWeek chairs Inger Damon, M.D., and Tom Talbot, M.D., discuss this year's annual meeting with HD Live!

NHLBI Trial Concludes No Benefit for Hydroxychloroquine in COVID-19

No clinical benefit found for hydroxychloroquine versus placebo in hospitalized adults with COVID-19

Incidence of Restless Leg Syndrome High in Pregnancy

Variation seen by race, ethnicity, which is likely accounted for by other risk factors such as age, parity, nutritional factors

E. Coli Outbreak May Be Linked to Recalled Romaine Lettuce

Five patients have been hospitalized; no deaths have been reported

DBT + Synthetic Mammography Better at Repeat Screening

Cancer detection rate higher for repeat screening with digital breast tomosynthesis + synthetic mammography versus full-field digital mammography

Most Pediatric Cases of Abusive Head Trauma Occur in Private Homes

In 98.5 percent of the cases, usual child care arrangement was by a single adult in charge of one or more children

Many at Risk for Severe COVID-19 Have Essential Jobs

Up to 74 million U.S. adults at risk for severe infection are essential workers or live with one

COVID-19 Infection Higher Among Support Staff Than Doctors, Nurses

Black and Latino workers have twice the odds of a positive virus or antibody test

Intentional Violent Injuries Up During Peripandemic Period

Proportion of intentional violent injury significantly greater during peripandemic months versus prior years, especially from firearms

Disparities Seen in Internet Access for Those With Chronic Conditions

Internet use lower among those with hypertension and diabetes and among Blacks and Hispanics

Tool Could Optimize Antibiotic Prescribing for UTI

Authors say decision support tool could help reduce antibiotic resistance by cutting use of broad-spectrum antibiotics

AHA: CVD Risk Often Unaddressed for Transgender Population

Of those receiving gender-affirming hormone therapy, many have CV risk factors and are not receiving appropriate therapies

New Equation Estimates GFR Across Age Spectrum

But EKFC equation was developed and validated only in White populations

AHA: Young Adults With CVD Have Low Flu Vaccination Rates

Prevalence of flu vaccination lower among adults aged 18 to 34, 35 to 44 years with versus without history of MI

Antibody Treatment Approved for Emergency Use Against Early COVID-19

Treatment approved for people newly infected with COVID-19 who are at high risk for progressing to severe disease

AHA: Remote Cardiac Rehab Is Effective Alternative to On-Site Programs

Two studies show no significant reduction in patient acceptance, adherence to virtual CR; remote CR as effective as outpatient CR

Multivitamin, Multimineral Users Self-Report Better Health

No differences seen in history of 10 chronic diseases, current health conditions, severity of psychological distress, rates of needing help with daily activities

USPSTF Finds Evidence Lacking for Child HTN Screening

I statement based on lack of studies examining benefits and harms of screening, impact of treatment on outcomes in adulthood

Spinal Cord Stimulation May Ease Diabetic Nerve Pain

Early results of clinical trial show high rate of responders who achieved ≥50 percent pain relief

AHA: PTSD Tied to Ischemic Heart Disease in Female Veterans

Findings most pronounced in younger women and racial and ethnic minorities

New Cancer Drug Approvals Linked to Drop in Mortality

New cancer drugs approved between 2000 and 2016 associated with 1,291,769 fewer related deaths in the U.S.

Cabotegravir Injection Can Protect Women From HIV for Two Months

Experimental drug found to be 89 percent more effective at preventing HIV infection than Truvada pills

Medicare Outpatient Premium to Rise

Monthly premium for outpatient care will rise by $3.90 next year

Panel Recommends Against Approval of Experimental Drug for Alzheimer Disease

FDA panel concluded there is not enough evidence to support the clinical effectiveness of aducanumab

About One in Five Children Have Vaccine-Hesitant Parent

Influenza vaccine coverage 26 percent lower for children of parents reported to be hesitant about childhood shots

Life Expectancy Has Increased for Individuals With IBD

However, there is still a gap in life expectancy, health-adjusted life expectancy between those with and without inflammatory bowel disease

Stroke Risk Increased With Depressive Symptoms

Middle-aged and older Black and White adults have increased stroke risk with CES-D-4 scores of 1 to 3, 4 or more

Low-Dose CT Offers Opportunity to Screen for Osteoporosis

Chest CT scans performed for other indications can identify adults with low bone mineral density

Preexisting Tinnitus May Be Exacerbated by COVID-19

Tinnitus exacerbated for those self-isolating, feeling lonely, sleeping poorly, exercising less

Hospital Stays After Delivery Shorter With Pandemic Protocols

Despite shorter stays, no differences seen in maternal or newborn adverse outcomes

Drug-Linked Endogenous Endophthalmitis Hospitalizations Up

2003 to 2016 saw fourfold increase in drug use-related endogenous endophthalmitis hospitalizations in the United States

Higher Health Literacy Linked to Odds of PSA Screening

However, patients with higher health literacy less likely to undergo PSA screening in the presence of shared decision-making

Broader Genetic Testing Could ID More Heritable Cancers

Universal genetic testing catches genetic mutations not detected in guideline-based testing

‘Watch and Wait’ Feasible for Some Rectal Cancer Patients

Some patients with complete response to neoadjuvant chemoradiation may wish to defer surgery

Pfizer COVID-19 Vaccine Reaches 90 Percent Effectiveness in Early Analysis

Vaccine requires two doses, given three weeks apart

COVID-19-Linked Ischemic Strokes More Severe

More severe disability on discharge and more inpatient death reported for ischemic stroke in COVID-19 patients versus controls

Global Burden High for Musculoskeletal Disorders

From 1990, slight decrease seen in age-standardized prevalence, disability-adjusted life year rates

Multinutrient Intervention Slows Cognitive Decline in Alzheimer Disease

Cognitive decline significantly reduced for Neuropsychological Test Battery five-item composite, memory, brain atrophy measures

Gun Violence Curriculum Benefits Surgical Trainees

Curriculum covers technical, nontechnical skills necessary to care for gun violence victims

Vitamin D Supplementation May Aid Severe Dermatitis

EASI score significantly lower for pediatric patients receiving vitamin D3 versus placebo with 1 percent hydrocortisone cream

Regulators Discuss Approval of New Alzheimer Disease Drug

Aducanumab does not cure or reverse Alzheimer disease; high dose may slow mental decline

Irritated Skin Tied to Pressure Injuries in Critical Care Patients

Treating, monitoring irritated skin may prevent pressure injuries

Unhealthy Drinking Habits Seen With Some Psychiatric Disorders

People with depression, anxiety disorder, or bulimia more likely to exceed daily, weekly alcohol limits

Considerable Decreases Seen in Health Care Use During COVID-19

Reductions reported in colonoscopies, mammograms, child vaccines, in-person office visits; telemedicine service use up in March, April 2020

Restricting Symptoms at the End of Life Decreasing

Decreases seen for difficulty sleeping; chest pain or tightness; shortness of breath; cold or flu symptoms; and nausea, vomiting, or diarrhea

Maternal Heart Health Predicts CVD Onset in Offspring

Offspring of mothers with ideal CV health live nine more years free from CVD than offspring of mothers with poor CV health

Drug Combo Offers Long-Term Glycemic Control in T2DM

Reduction in HbA1c at 104 weeks greater with exenatide plus dapagliflozin versus either drug alone

College Campuses See Rise in COVID-19 Cases

More than 38,000 campus cases have been reported in the past two weeks

Mortality Down for Cancer Patients With Medicaid Expansion

Mortality reduced for patients with newly diagnosed breast, colorectal, lung cancers, mediated by earlier stage of diagnosis

Review: Nearly One in Five With SARS-CoV-2 Has GI Manifestations

Sixteen percent of COVID-19 cases may only present with gastrointestinal symptoms, which include nausea, vomiting, diarrhea

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...