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Carnivorous pattern linked to increased risk for ulcerative colitis; Western dietary pattern linked to increased risk for Crohn disease

Incidence and prevalence highest in Northern Europe, North America; lowest in Southern Europe, Asia, Middle East

Incidences of major adverse cardiovascular events, cancers higher with tofacitinib versus TNF inhibitor; criteria for noninferiority not met

Real-world data support the use of remdesivir for hospitalized COVID-19 patients receiving no oxygen or low-flow oxygen

All-cause inpatient admissions 2.8 times more likely, death 1.5 times more likely during foot ulcer episodes versus period after healing

Lower respiratory infections accounted for >1.5 million deaths associated with resistance, making it the most burdensome syndrome

Reporting rates 3.83 per million vaccine doses for Ad26.COV2.S versus 0.00855 per million for mRNA-based vaccines

Stronger association seen for moderate- to vigorous-intensity steps per day than for light-intensity steps per day

Vaccine effectiveness against COVID-19 hospitalization increased with third dose in those with, without immunocompromising conditions

Vitamin D supplementation, with or without omega-3 fatty acids, linked to reduced risk for autoimmune disease

New study will focus on a single omicron-specific booster dose in about 600 adults

Higher levels of Ruminococcus gnavus, Bacteroides vulgatus, lower levels of Faecalibacterium prausnitzii observed in patients with PACS

The variant, called BA.2, has genetic traits that make it somewhat more difficult to detect

Prevalence ratios for chronic obstructive pulmonary disease increased with ever exposure, high cumulative exposure to pesticides at work

Other U.S. hospitals have also faced criticism for denying transplants to patients who were not vaccinated against COVID-19

Largest increases in distant-stage proportion for rectal-only seen for 20- to 29-year-old non-Hispanic Blacks, Hispanics

Significantly more ischemic strokes seen in women than men among those aged 35 years and younger, but not among 35- to 45-year-olds

SARS-CoV-2 infection associated with short-term transient decline in fertility for men

Promoting low-dose CT screening among mostly nonsmoking women increased detection of early-stage, but not late-stage, lung cancers

No such increased risk seen with Sinovac inactivated virus vaccine

Evidence currently inadequate for assessing the balance of benefits and harms of screening for atrial fibrillation in asymptomatic adults

Mean length of stay and percentages admitted to ICU, receiving invasive mechanical ventilation, dying lower during omicron

ACIP recommends PCV20 alone or PCV15 in series with PPSV23 for all aged 65 years and older or younger adults at risk

Risk for early-onset sepsis low among infants of all gestational ages born with low-risk delivery characteristics

For asymptomatic SARS-CoV-2-positive individuals living with infected household contact, combo cuts incidence of symptomatic COVID-19

Mortality rate increases with increasing sequential organ failure assessment score on admission, respiratory failure, maximum lactate level

Preferred approach described for managing ACLF, now emerging as a major cause of mortality in patients with cirrhosis, chronic liver disease

Fewer hospital admissions reported for respiratory, severe invasive, and vaccine-preventable infections

Patients with symptoms of anxiety significantly more likely to use psychotropic medications after hospital discharge

Approval based on two Phase 3 trials showing more than 50 percent of patients receiving Skyrizi achieved ACR20 response at 24 weeks

Three-month survival 95.6 percent among patients who underwent lung transplant during August 2020 to September 2021

And vaccine effectiveness lower during omicron with receipt of two doses, but higher after booster dose

Surgical patients in hospitals with good nurse environment less likely to be admitted to ICU, have 30-day mortality

Since the start of the pandemic, more than 10.6 million children have tested positive for COVID-19

Supreme Court said mandate went too far in imposing such a sweeping requirement on employers

Weight loss before infertility treatment in obese women not associated with improvement in healthy live birth rate

Consumption of a suite of ready-to-eat bioactive foods tied to 8.8 percent drop in LDL cholesterol in four weeks

Promoting low-dose CT screening among mostly nonsmoking women increased detection of early-stage, but not late-stage, lung cancers

Vaccine effectiveness 75 percent during 2019 to 2020 season, when vaccine-mismatched viruses predominated

Blood test based on four-marker protein panel combined with risk prediction model may improve assessment of risk for lung cancer

About 21 percent of adults diagnosed with acute PE in primary care sent home; few experienced adverse events within 30 days

Parents report much higher use of helmets during snowmobiling, skiing/snowboarding

Novel prognostic index CLL-WONT identifies patients with chronic lymphocytic leukemia who are at low risk for ever requiring treatment

Findings show modest, but significant, benefit from either compassion-based or mindfulness-based self-help

Those presenting with fatigue early likely to see it persist

Palpitations common, but corresponded with sinus rhythm or sinus tachycardia

Proportion of internal medicine applicants and matriculants who identify as underrepresented in medicine remained low during 2010 to 2018

New U.S. study will assess the updated, omicron-targeted vaccine for use as a booster or for primary vaccinations

More states have now reported they have passed their peaks in new cases, and new cases have begun to drop nationally

Announcement made a day after the WHO said the spread of the omicron variant could change the pandemic from overwhelming to manageable

Masks already set up for distribution at some Hy-Vee and Meijer grocery stores in the Midwest

Treatments made by Regeneron and Eli Lilly performed well against earlier variants, but not against omicron

Allopurinol initiation, achieving target serum urate levels, allopurinol dose escalation not associated with increased mortality

Findings seen regardless of whether a person has normal, overweight, or obese BMI at baseline

Compared with homologous booster, heterologous booster with mRNA-based vaccine yielded larger increase in binding antibodies

Investigational oral live microbiome therapeutic superior to placebo in patients with three or more episodes of C. difficile infection

However, nonlinear association seen between night shifts and chronic lymphocytic leukemia

Links found for frailty with in-hospital mortality, prolonged length of stay for patients with NHL, HL, MM undergoing aHSCT

Compared with White patients, Black patients have 2.54 times the odds of having at least one negative descriptor in EHR

MRI-detected tenosynovitis independently associated with progression to rheumatoid arthritis

Treatments made by Regeneron and Eli Lilly performed well against earlier variants, but not against omicron

Standardized incidence ratio was 3.0 during first year of follow-up after VTE and decreased to 1.5 during subsequent years

Mask mandates to be lifted this week, as England relies on vaccinations and testing to keep the virus in check

During period of delta predominance, protection was lower among vaccinated persons without previous COVID-19 diagnosis

In response to the incident, Hartford officials pledged to ensure that all city schools are stocked with naloxone

51 percent of institutions cite decreased clinical staff availability; HCPs experiencing psychological distress, financial concerns

Vaginal seeding has no known benefits and may expose neonates to vaginal pathogens; umbilical nonseverance has no clear benefit

Overall survival, but not progression-free survival, improved with tremelimumab plus durvalumab versus sorafenib for unresectable HCC

Overall survival, progression-free survival prolonged in those receiving durvalumab versus placebo in addition to gemcitabine and cisplatin

However, some small but significant increases and decreases seen in specific geographic areas

Statistically significant linear increase observed in mortality from five hours after time of arrival at emergency department up to 12 hours

Percentage of time with glucose level in target range higher during closed-loop period versus sensor-augmented pump therapy period

Findings reported for subcutaneous treatment in overweight, obese adults also using diet, physical activity

Increased incidence of diabetes seen among patients aged younger than 18 years after acute COVID-19 infection versus those without COVID-19

Health behavior impacts showed a dose-response relationship with mental health distress

35 percent higher risk for venous thromboembolism seen with watching more than four hours of TV daily

Exploratory analysis shows link between optical defocus treatment and slower progression of myopia in school-aged children

Findings seen in second phase of the pandemic; no significant racial differences seen during the beginning of the pandemic

But protection against COVID-19 hospitalization, death after two doses of BNT162b2 or CHAdOx1-S is more durable

However, government's order for the free test kits is in addition to existing supply and does not interfere with existing orders

Measurement of prefrontal cortex oxygenated hemoglobin concentration with functional near-infrared spectroscopy may detect THC impairment

Chances of hospitalization for COVID-19 more than 40 times higher for those who are unvaccinated than for those with full vaccination and booster

Increased market growth of biosimilars that are similar to brand-name biologic agents has the potential to reduce spending on prescription drugs

More children who received immunotherapy met the primary outcome of desensitization and remission criteria

Risk for hypertension even higher for those receiving left-sided radiation therapy, endocrine therapy

Faster increase seen for total hip arthroplasty, while total knee arthroplasty has slightly higher odds of complications

Significant predictors of pandemic weight gain were psychological distress, prepandemic weight, and children at home

Claims data for private insurance and Medicare Advantage plans show spike in inappropriate ivermectin prescriptions for COVID-19

Life challenges more negatively impacted in younger, female, relapsed patients; socializing more positively impacted in older patients

Prediction accuracy of the nomogram higher than that of Ann Arbor Stage for primary intestinal non-Hodgkin lymphoma patients

However, no reduction observed in prescribed opioid quantity

Fourth dose of mRNA vaccine increased antispike IgG titers in some kidney transplant recipients with weak serologic response after three doses

Findings show inclusion significantly cuts odds of pressure injuries in patients hospitalized with severe COVID-19

Previously hospitalized patients had twice the health care utilization of nonhospitalized COVID-19 patients

Two doses of RZV recommended for adults 19 years and older who are immunocompromised due to disease or therapy

Rates for three largest race and Hispanic-origin groups did not significantly change; increase in rates reported in one state, decline reported in two states

No evidence of temporal association seen between invasive dental procedure and late prosthetic joint infection

But authors say use of mental health services is not increasing among those who attempt suicide

Compared with meeting EPA standards alone, this would prevent 11,850 more deaths, 25,400 more morbidities

Machine learning model incorporates data from 14 proteins derived from a single blood sample to predict survival in patients with COVID-19

Compared with 2013 USPSTF criteria, more patients eligible for lung cancer screening with less racial disparity in access

Two doses highly effective against COVID-19-related hospitalization and critical illness for those aged 12 to 18 years

Inability to fulfill elements of decisional capacity coupled with need for rapid treatment decisions complicates consent

Fewer than 10 percent of people in lower-income countries have received one dose of COVID-19 vaccine

Move follows updated mask guidance issued by the CDC late last week

As of Jan. 27, COVID-19 passes will no longer be needed to enter large-scale events, use of face masks in public schools will no longer be required

Monoclonal antibody treatment used infrequently among all racial, ethnic groups; Hispanics received mAbs less often than non-Hispanics

Dermatologists and patients with psoriatic disease approve of a specialist-led model of care

All deformation parameters on echocardiogram recovered within first week, including LV global longitudinal strain, peak left atrial strain

Approval indicated for those 12 years and older with atopic dermatitis that has not responded to previous treatment

An increase in the gap between retinal age and chronological age, known as the retinal age gap, may increase the risk for mortality

Exposure to air pollution greater for certain racial/ethnic groups, low-income groups

29 percent of patients deemed appropriate for intervention were Hispanic compared with 52 percent of those deemed not appropriate

Procurement and transplant of stage 3 AKI kidneys has increased, but discard rate is still high

Guidelines address diagnosis and management, use of diagnostic colonoscopy in complicated disease, and interventions to prevent recurrence

EBRT strongly recommended as potential first-line therapy for patients with HCC confined to liver who are not candidates for curative therapy

Guideline-nonconcordant radiotherapy given to substantial proportion of Medicare beneficiaries with metastatic cancer near the end of life

For adults without known CVD risk factors, individualize the decision to refer to behavioral counseling to promote healthy diet, physical activity

Risk for MS increased 32-fold following EBV infection, but not following infection with other viruses, including cytomegalovirus

Adding a P2Y12 inhibitor to a therapeutic dose of heparin does not improve outcomes among non-critically ill patients hospitalized for COVID-19

Incidence higher for men versus women, adults older than 70 years, and individuals living in high social-demographic index regions

From 2000 to 2019, overall survival progressively improved for patients with Philadelphia-positive ALL who had posttransplant relapse

During the week ending Jan. 9, U.S. nursing homes reported more than 32,000 cases and 645 deaths among their residents

Early launch due to 'beta testing'; website currently working at 'limited capacity' ahead of official Wednesday debut

Thirty-six of the organization's 194 member countries have still only vaccinated 10 percent of their populations

There are suggestions that omicron could result in COVID-19 transitioning from a pandemic to an endemic situation

Achieving sustained changes requires multidisciplinary teams, multidimensional educational programs, multilevel interventions

Presence of an appendicolith increases risk for undergoing appendectomy after starting antibiotic therapy for acute appendicitis

Patterns of medication use for obesity-related comorbidities slightly more favorable following gastric bypass versus sleeve gastrectomy

Young adults with secondhand vape exposure have increased odds of bronchitic symptoms, shortness of breath

In addition to managing all cardiovascular risk factors, providers must consider social determinants of health

Age, underlying chronic illness, and symptom duration tied to severe outcomes

Fosfomycin not noninferior to ceftriaxone or meropenem for bacteremic urinary tract infection due to multidrug-resistant E. coli in adults

Authors urge primary care physicians to make case-by-case basis decisions based on benefit-to-risk

Access to GAH during adolescence, adulthood linked to lower odds of past-year suicidal ideation versus desiring but not accessing GAH

However, most costs are paid out of pocket

Easing the rules would result in a 2 to 4 percent increase -- 345,400 to 615,300 more pints of blood -- in the nation's annual blood supply

Among those who voted against Califf's nomination were Democrats who expressed concerns about his links to pharmaceutical companies

Severe depressive and sexual symptoms of menopause associated with worse cognitive performance

Mandate was a crucial component of the White House plan to tackle the COVID-19 pandemic

For those aged 45 to 49 years, 32 percent had any neoplasia, 7.5 percent had advanced premalignant lesions, 0.58 percent had CRC

JAK inhibitor baricitinib strongly recommended for the treatment of severe or critical COVID-19

Regular physical activity levels linked to slower deterioration of postural and gait stability, activities of daily living, processing speed

The NCCN Advisory Committee supports the strong preference for mRNA vaccines and offers guidance on the timing of vaccination

Rural home health care agencies perform better on process measures; urban agencies perform better on outcome measures

No similar findings seen for middle-aged women

Woven EndoBridge device effective for treating ruptured and unruptured aneurysms in all intracranial locations

Risk for overactive bladder varies across individual cholinesterase inhibitor drugs

Incidence increased from 2004 to 2018, and among non-Hispanic Asian or Pacific Islander women and those aged 20 to 39 years

Risk for both all-cause and cancer-specific death increased for cancer survivors with combination of prolonged sitting and inactivity

Struggles include finding the right medication and medication side effects

KFRE score >20 percent had similar specificity, higher sensitivity for predicting end-stage kidney disease than eGFR <20 mL/min/1.73 m²

Higher risk seen for low birth weight and preterm birth with statins, but no tie to congenital anomalies

After three or more years of therapy, drug holidays from risedronate versus alendronate linked to 18 percent increase in hip fracture risk

One option being discussed is to distribute the masks at community sites

Decrease in antibiotic prescriptions in pediatric primary care driven by reduced volume of visits for respiratory tract infections

More than 1,000 will begin arriving at hospitals nationwide starting next week

During 2014 to 2018, incidence continued to increase slowly for female breast cancer, remained stable for prostate cancer

Cluster of false-positive results likely the result of manufacturing issues, rather than implementation

Replacing butter, margarine, mayonnaise, dairy fat with olive oil linked to reductions in total, cause-specific mortality

Outcomes better for Black men compared with White men in clinical trials of definitive radiotherapy for localized prostate cancer

Also, work absences common for primary caregivers after critical care hospitalization of child for acute respiratory failure

Pfizer also working to improve its current COVID-19 vaccine 'to address any future variant of potential concern, if needed'

Positive additive interaction linked to increased risk for breast cancer particularly in postmenopausal women

Patient outcomes similar for certain procedures performed by residents alone, attending surgeons alone, residents assisted by attending surgeons

All reprocessed N95 respirators met primary end points of function and effectiveness; no change reported in filtration efficiency

Since the start of the pandemic, nearly 8.5 million U.S. children have tested positive for COVID-19

One model suggests number of daily reported cases in the U.S. will top out at 1.2 million by Jan. 19 and then fall sharply

Myopia incidence from age 20 to 28 years was 14 percent

Earlier preliminary studies had raised questions about whether rapid antigen tests might be less sensitive to omicron than other variants

Prevalence of depression increased among adults and children with hidradenitis suppurativa

First shipments are expected later this month

Increased frequency, severity of ED visits for cannabis exposure in children tied to legalization of commercial cannabis edibles in Ontario

Race coefficients applied to calculation of eGFR in non-Black transplant candidates to demonstrate more equitable preemptive listing

Improvements show long-term effect up to 12 months following a three-month intervention

Two doses of Pfizer-BioNTech vaccine have estimated effectiveness of 91 percent against MIS-C in children aged 12 to 18 years

Authors say validated psychophysical tests can better identify true burden of chemosensory dysfunction

Surge in cases has overwhelmed hospitals nationwide, and about one-quarter face critical staffing shortages

Combination improved pain management for teens undergoing spinal fusion for scoliosis

Under the plan, people who provide insurance information at certain pharmacies will be able to get the tests with no out-of-pocket costs

However, grip strength and physical functioning were tied to lower risk for death, regardless of weight

People who have received COVID-19 vaccines can donate blood and platelets as long as they are symptom-free

High psychological distress tied to lower quality of life, social isolation, impaired cancer care

Agency has placed Canada under a Level 4 travel health notice, which is the highest category

However, wide variation seen in provider uptake

The Maryland heart patient is still doing well three days after the procedure was performed

Mindfulness practices combined with active rather than sham transcranial direct-current stimulation showed greater benefit

Updates include recommendation to screen for prediabetes and diabetes in all people starting at age 35 years

Among parous women, risks for CVD, coronary heart disease, stroke, fatal CVD reduced for those who ever, versus those who never, breastfed

Long-term exposure to low levels of air pollutants linked to increased incidence of COVID-19 in city in Northern Italy

Children experiencing hybrid learning have better outcomes than with remote learning, worse behavior than with in-person learning

Throat swabs are common in some countries, but most self-tests in the United States require nasal samples

Factors linked to health declines include higher BMI, lower level of education, current smoking, osteoarthritis, depression, CVD

Announcement comes shortly after Aduhelm maker Biogen cut the price of the drug by about half, from $56,000 to $28,000 a year

Difference in change in cycle length between vaccinated and unvaccinated cohorts less than one day in adjusted models

Attorney General offices around the country have reported receiving complaints or hearing stories of price gouging

Discontinuation of ACE-I, ARB, metformin associated with elevated risk for death among hospitalized COVID-19 patients

Headache-related impairment did not improve, but headache frequency reduced and psychological functioning improved