Dialectical Behavior Therapy Tied to Fewer Suicide Attempts

Findings seen for the high-risk population of teens with bipolar spectrum disorder

High-Intensity Statins Underused With Atherosclerotic Cardiovascular Disease

Authors say findings show gaps between practice and guideline-based care

Subsequent Breast Cancer Risk Higher for Child Cancer Survivors Receiving Doxorubicin

More than twofold increase in risk seen for those treated with ≥200 mg/m² cumulative doxorubicin versus no doxorubicin

Cediranib Shows Promise for Differentiated Thyroid Cancer

No significant improvement in progression-free, overall survival seen with addition of lenalidomide to cediranib

Respiratory Infections in Childhood Increased With Urbanized Living at Birth

Environmental factors, including breastfeeding and visible damp, are associated with risk for infections

USPSTF Recommends Screening for Hypertensive Disorders of Pregnancy

Screening with blood pressure measurements has substantial net benefits and is recommended throughout pregnancy

Four Genetic Variants ID’d for Risk for Progressive Multifocal Leukoencephalopathy

All four risk variants were predicted to be deleterious and were located in two immune pathways

Pneumococcal Infection Reduced in Children With Sickle Cell Since PCV13

After 2010, all invasive pneumococcal infection serotypes were those not included in 13-valent pneumococcal conjugate vaccine

Extended-Release Buprenorphine Not Necessarily Cost-Effective

Extended-release buprenorphine not cost-effective when transmucosal buprenorphine is available for treatment of OUD

Premenopausal Bilateral Oophorectomy Linked to Chronic Conditions

More chronic conditions seen in late midlife for women with history of PBO with or without hysterectomy

Sputum Purulence Can Predict Outcomes in Bronchiectasis

Patients with more purulent sputum experience more exacerbations and more severe exacerbations

Cases of Pediatric Therapeutic Errors Related to ADHD Meds on the Rise

Likelihood of experiencing a serious medical outcome or being admitted to a health care facility was increased for children younger than 6 years

AAP Issues Low-Carb Diet Recommendations for Pediatric Diabetes

Safety concerns to consider for youth with diabetes who are restricting carbohydrates include growth deceleration, poor bone health

Ventilatory Burden Can Assess Severity of Obstructive Sleep Apnea

Ventilatory burden can also predict all-cause and cardiovascular disease mortality

Revaccination Suggested for Hep B Vaccine Nonresponders After Hep C Cure

Revaccination should be considered for patients with chronic HCV who do not respond to HBV vaccination

Use of AI Plus One Radiologist Noninferior for Detecting Breast Cancer

Double reading by one radiologist plus AI noninferior to standard-of-care double reading by two radiologists

Risk for Intracerebral Hemorrhage May Be Transmissible Via Blood Transfusion

Risk was increased for those receiving transfusion from donors who later developed multiple spontaneous intracerebral hemorrhages

Advanced Young-Onset Adenoma Increases Colorectal Cancer Risk

However, overall 10-year colorectal cancer incidence relatively low in veterans younger than 50 years of age

AI Tool May Aid Remote Assessment of Parkinson Symptom Severity

Performance better than certified rater but not quite as good as expert neurologists

Both Maternal, Paternal Substance Use Disorder Tied to Offspring Intellectual Disability

Authors say preventive efforts should focus on fathers, too

Air Pollution Exposure Tied to Smaller Babies at Birth

However, living in a greener area could help counteract this effect

Economic Burden of Youth Violence Reached $122 Billion in 2020

Total annual economic burden of youth violence 17 percent higher in 2020 due to increase in youth homicides

Infection With Omicron Less Likely to Result in Post-COVID-19 Condition

No variation in risk for PCC seen based on number of vaccinations, but previous infection linked to reduced PCC risk

Parent-Support Early Childhood Obesity Intervention Beneficial

No between-group difference seen in BMI-standard deviation score, but significant difference seen in reduction of BMI-SDS ≥0.5

Memories Reported by Some Patients Undergoing CPR for Cardiac Arrest

Normal EEG activity consistent with consciousness emerged as long as 35 to 60 minutes into CPR despite marked cerebral ischemia

Head Injury Linked to Increase in Incident Ischemic Stroke

Dose-response association seen for risk for stroke with number of head injuries, but no association seen for severity

Physical Therapy Linked to Drop in Falls for Patients With Dizziness

Receipt of physical therapy within three months of presentation linked to reduced risk for subsequent falls

Tobacco, Cannabis Use Tied to High Rates of Self-Reported Mental Health Issues

Daily use of cigarettes, e-cigarettes, and cannabis associated with both anxiety and depression

Reproductive Factors Linked to Risk for Lung Cancer

Early menarche, early menopause, shortened reproductive life span linked to increased risk, especially for NSCLC

Lorundrostat Effective for Lowering BP in Uncontrolled Hypertension

Changes in office systolic BP of −14.1, −13.2, −6.9, and −4.1 mm Hg seen with 100, 50, 12.5 mg once daily of lorundrostat and placebo

Use of Nonselective β-Blockers Tied to Lower Risk for Total Knee Arthroplasty

Any β-blocker use cuts odds by nearly half, driven by nonselective β1-blockers

Concurrent Use of Fentanyl, Stimulants Common in Overdoses

Proportion of stimulant involvement in fentanyl-involved overdose deaths increased in almost every state from 2015 to 2021

E-Cigarettes, Cytisine, Varenicline Most Effective to Help Stop Smoking

Combination of a patch and fast-acting nicotine replacement therapy also effective

Rates of Sexual Dysfunction High in Patients With Schizophrenia

Review showed that treating depression was associated with lower rates of sexual disorders

HRQoL Consistently High for Out-of-Hospital Cardiac Arrest Survivors

Long-term health-related quality of life consistently high up to 20 years after the event

Diet, Exercise Intervention May Aid Chemotherapy Outcomes in Breast Cancer

Although relative dose intensity similar, pathologic complete response higher with intervention

Choking Hazard Spurs Recall of Bath Toys Sold at Target

Consumers should immediately stop using the recalled water bead kits and take them away from children

BNT162b2 Vaccination Linked to Lower Risk for COVID-19 Encounters in Children Under 5

Vaccination linked to reduced odds ratio of COVID-19-related emergency department or urgent care encounter, outpatient visits

Intensity-Modulated Radiation Therapy Best for Locally Advanced NSCLC

Intensity-modulated radiation therapy spares more normal tissue than 3D-conformal radiotherapy

Treatment of Lower Urinary Tract Symptoms Tied to Reduced Risk for Death in Men

Significant reductions seen in death with 1-point improvement in AUA Symptom Score, and in storage and voiding subscales

Home-Based Ovulation Monitoring Feasible for Timing Frozen-Thawed Embryo Transfer

No difference seen in ongoing pregnancy versus hospital-controlled ovulation monitoring

Minimally Processed Red Meat Can Work in Weight Loss Diet With Diabetes

High-protein, lean beef diet achieved similar weight loss, glucose control as normal-protein diet with no red meat

Interventions Can Increase Adjuvant Endocrine Treatment Adherence

Findings based on meta-analysis involving more than 360,000 breast cancer survivors

Immune Response Not Inferior With Coadministration of COVID-19, Flu Shots

Similar immune response and no increase in rate of reactogenicity events seen with coadministration versus COVID-19 vaccine alone

Factors Identified for Readmission Among Children With ARDS

Respiratory and nonrespiratory complex chronic conditions, tracheostomy placement, LOS ≥14 days linked to readmission; one-year readmission probability was 30 percent

Improvement Seen in Reproductive Hormone Levels With Keto Diet in PCOS

LH/FSH ratio and serum free testosterone reduced, while serum sex hormone-binding globulin increased with ≥45 days of diet

Exercise Stress Tests Can Also Predict Noncardiovascular Deaths

Low functional aerobic capacity, abnormal heart rate recovery, and low chronotropic index tied to noncardiovascular death

Hypertension, Statin Use Increased for Individuals Using TAF for PrEP

Incident hypertension, statin use higher with tenofovir alafenamide fumarate compared with tenofovir disoproxil fumarate

Increasing Proportion of Visits Delivered by Nurse Practitioners, PAs

Proportion of visits delivered by nonphysicians varies across conditions, from 13.2 percent for eye disorders to 41.5 percent for respiratory infections

Parent Drinking Behaviors Linked to Adolescent Drinking

Teens whose parents drink frequently or binge drink have significantly higher odds of drinking

Seniors With Digestive Disease More Likely to Have Loneliness, Depression

Loneliness, moderate-to-severe depression associated with greater odds of poor-to-fair health

Beauty Salon-Based Intervention Builds Knowledge of PrEP in Black Women

One challenge is that women perceive their risk for HIV infection as low

Online Peer-Delivered Cognitive-Behavioral Therapy Aids Postpartum Depression

Other benefits seen for improved maternal social support, infant-focused anxiety, and negative emotionality in infants

Racial Disparities Seen in Presentation of Frontotemporal Dementia

Black individuals exhibit higher frequency of delusions; Asian individuals have higher frequency of apathy

Prescribed Medical Cannabis Use Tied to Better Health-Related Quality of Life

Findings seen in real-world patients with a range of chronic health conditions

Methylation Score Can ID Risk for Cervical Adenocarcinomas

Methylation score had sensitivity of 74 percent, specificity of 89 percent for adenocarcinoma in situ/adenocarcinoma

Seasonal Difference Observed in Systolic Blood Pressure

Seasonal variation of 1.4 mm Hg tied to nearly 5 percent variation in blood pressure control

Hypertension While Lying Down Tied to Worse Cardiovascular Disease Outcomes

Findings seen regardless of whether hypertension persists in seated position

Testosterone Therapy Tied to Better Mental Health

Findings seen for transgender and gender-diverse individuals desiring testosterone therapy

Cardiac Arrest Survival Lower at EMS Agencies Serving Minority Populations

Difference not explained by response times, rates of EMS termination of resuscitation, or rates of initiating CPR or automated external defibrillator

Hypoattenuation Thickening on CT Prognostic After Left Atrial Appendage Occlusion

High-grade hypoattenuation thickening on follow-up CT after left atrial appendage occlusion associated with higher stroke risk

CDC Panel Gives Support to New COVID-19 Booster Shots

New booster targets the XBB.1.5 omicron subvariant, which is similar to the dominant variant now circulating

Risk for Dementia Reduced in Association With Antihypertensive Use

Individual patient data meta-analysis shows increased risk for dementia for those with untreated hypertension

Receipt of PT, Chiropractic Care Reportedly Low for Comorbid Chronic LBP, Opioid Use Disorder

Receipt of physical therapy and chiropractic care was low overall and lower across racial, ethnic minorities

AACR Cancer Progress Report Reveals 33 Percent Decrease in Cancer Death Rate, 1990 to...

Report highlights advances such as approval of 14 new anticancer therapeutics, expansion of use of 12 previously approved therapeutics

17 Percent of Patients Seeing Neurologist Travel Long Distance

Factors associated with long-distance travel include low neurologist density, rural setting, and visits for ALS, nervous system cancer

A Year After Launch, OTC Hearing Aids Are Not Catching on With U.S. Consumers

A year after the U.S. Food and Drug Administration approved the devices, only a small fraction of people with hearing difficulties have bought one

California Legislature First to Pass Ban on Four Food Additives Linked to Health Issues

The chemicals are already illegal in the European Union and other places around the world

Whites Have Greatest Magnitude of Association of Socioeconomic Status With LE8

Magnitude of positive association for four socioeconomic status categories with LE8 was greater for non-Hispanic Whites than minority groups

Adults Overdue for CRC Screen Rarely Receive Recommendation for Screening

Prevalence of reporting clinician recommendation was lower for non-Hispanic Asian, Black, Hispanic versus White adults

Lead Exposure Poses Considerable Global Health, Economic Burden

>90 percent of total global IQ loss and cardiovascular disease deaths occurred in low-, middle-income countries

Shorter Leucocyte Telomere Length Linked to Dementia Risk

Shorter leucocyte telomere length also associated with smaller total brain volume, white matter volume, hippocampus volume

Time Spent in Sedentary Behavior Tied to Incident Dementia in Seniors

Significant, nonlinear association identified between time spent in sedentary behavior and incident dementia

Coronary CTA-Derived Fractional Flow Reserve Can ID Three-Year Outcomes in Angina

Risk for all-cause death, nonfatal spontaneous myocardial infarction identified in overall cohort, those with high coronary artery calcium scores

Fine Particular Matter Linked to Increase in Breast Cancer Risk

Significant increase in risk seen for ER-positive breast cancer, but not ER-negative tumors

Half of Older Adults With Glaucoma Unaware They Have It

Furthermore, two-thirds with undiagnosed glaucoma had normal intraocular pressure

FDA Panel Says Common OTC Decongestant Is Useless

Panel's recommendation could prompt the FDA to pull all oral decongestants containing phenylephrine from store shelves

Curcumin, Omeprazole Similarly Effective for Functional Dyspepsia

Significant improvements seen in symptoms on days 28 and 56; no synergistic effect seen for combination treatment

Children With Down Syndrome Experience More Medical Imaging

More medical imaging, including CT, fluoroscopy, angiography, nuclear medicine, reported for those with Down syndrome, especially in those younger than 1 year

Few With CRC in Sub-Saharan Africa Receive Guideline-Concordant Care

Risk for death 3.49 times higher for those receiving no cancer treatment versus standard treatment or treatment with minor deviations

Antipsychotic Use Increased for Seniors With Alzheimer, Related Dementias

Among patients with ADRD receiving care from a home health agency, antipsychotic use was tied to less improvement in activities of daily living

ChatGPT Accurately Handles Questions About Vaccine Hesitancy

Findings seen for 50 most common questions about false information, myths, and false and true contraindications

ED Pediatric Readiness Cuts In-Hospital Mortality

However, pediatric readiness does not eliminate Black mortality disparity for children's medical emergencies

Objective Measures of Social Visual Engagement Aid Early Diagnosis of Autism

Test able to quantify diagnostic status as well as individual levels of social disability, verbal ability, and nonverbal ability

Evening Chronotype Linked to Increased Risk for Type 2 Diabetes

Positive association seen after accounting for all measured lifestyle and sociodemographic factors

Flu Vaccine Cut Risk for Influenza-Linked Hospitalizations in 2023

Interim data show vaccine effectiveness of 51.9 percent in five South American countries during their flu season

FDA Approves New COVID-19 Booster Shots

New booster targets the XBB.1.5 omicron subvariant, which is similar to the dominant variant now circulating

Red Cross Appeals for Donors During National Blood Shortage

Back-to-back climate-related disasters have hampered blood collection efforts, and a summer shortfall has made the shortage worse

Americans Who Are Deaf Can Now Use 988 Suicide Helpline

The services use a videophone device that transmits video and audio

Gefapixant Leads to Modest Improvements in Cough

Modest improvement seen in cough frequency, severity, and specific quality of life, but increase seen in treatment-, taste-related adverse events

Risk for Death, Cardiovascular Death Lower for OSA Patients Using CPAP

Reduction seen in low-density coronary artery plaque volume with CPAP and with use of CPAP and GLP-1-mediated weight loss

Increase Seen in COPD Hospital Admissions Since 2010 in Canada

Age-standardized rates increased among younger women and men and older women, while they declined in older men

Opioids Can Be Continued in Cancer Patients With Nonmedical Stimulant Use

Regardless of prognosis, panel deemed it appropriate to continue opioids, increase monitoring, and avoid opioid tapering

Heat Exposure During Pregnancy Linked to Severe Maternal Morbidity

Greater associations seen for mothers with lower educational attainment, those whose pregnancies started in cold season

Severity Reduced With Mpox Reinfection, Postvaccination Infection

Shorter disease course with less mucosal disease seen on reinfection versus initial infection

Link Explored for NSAID Use, Hormonal Contraception, VTE Risk

NSAID use positively linked to VTE, with extra VTE events in those with concomitant high-, medium-risk contraception use

Growing Pains May Be Precursor to Migraine

Significantly more children and adolescents with growing pains had headaches fulfilling criteria of migraine without aura, probable migraine

Being in Good Shape Tied to Fewer Mental Health Rx

Reduction in need for anxiolytic drugs, antidepressants strongest for men and young and middle-aged adults

Redo Transcatheter Aortic Valve Replacement Safe, Effective

Death and stroke rates similar to those in patients with a similar clinical profile and predicted risk undergoing TAVR for native aortic valve stenosis

Company Pulls ‘One Chip Challenge’ From Store Shelves After Teen Dies

Hospitalizations from the One Chip Challenge have been reported across the country

Patients May Not Have Choice in Behavioral Health Visit Modality

Nearly half of patients report they do not believe their clinician considered their modality preferences when deciding on in-person versus virtual visit

Pulmonary Embolism-Related Mortality Remained Unchanged From 2006 to 2019

Age-adjusted mortality rate increased for men versus women and Black versus White patients

Black-White Disparities in Cognition Declined Between 2008 and 2017

However, disparities persisted among seniors in functional limitations and limitations in activities of daily living

Depression, Inflammation Linked in Obese Patients Undergoing Bariatric Surgery

Higher baseline hsCRP predicts poorer weight loss but has no effect on depression severity

Alzheimer, Parkinson Disease Share Protective Association at HLA Locus

Protective HLA-DRB1*04 subtypes bind strongly to aggregation-prone tau PHF6 sequence when acetylated at K311

Hypertension, Anemia Contribute to Racial Disparities in Severe Maternal Morbidity

Population attributable risk percentage for antepartum anemia and SMM highest for multiracial, Black, Hispanic patients

Food Additive Emulsifier Intake Linked to Risk for CVD

Higher intake of celluloses (E460 to E468) positively associated with higher risks for CVD and coronary heart disease

Upfront Combo Lipid-Lowering Therapy Best for Acute Coronary Syndrome

Combination approach better than statin monotherapy for all-cause mortality at one, three, and five years in acute coronary syndromes

Small Changes in Bone Mineral Density Can Reduce Hip Fracture Risk

Small improvements in femoral neck BMD coincided with significant reduction in incidence of hip fracture in men and women

Linguistic Disparities Impact Patient Access to Cancer Care

Non-English-speaking patient callers to hospital are less likely to be provided with next steps to access cancer care

Providers Have Inadequate Awareness of PCV20 Vaccination Recommendations

Two-thirds of health care providers agree with expanding recommendations for new PCV20

Racial, Ethnic Disparities Seen in Type 2 Diabetes After GDM

Associations between education, Medicaid, WIC participation, body mass index with T2DM were more pronounced among White individuals

Adverse Association Identified for Calcium Channel Blocker Use, Glaucoma

CCB use also linked to thinner macular ganglion cell-inner plexiform layer, macular retinal nerve fiber layer thickness

Company Reaches $479 Million Settlement Over Defects in CPAP Machines

The machines were recalled in June 2021 by the U.S. Food and Drug Administration

Hepatitis C Virus Still Leading Cause of Hepatocellular Cancer in Men

Since 2017, leading cause of HCC is NAFLD among women; increases in ALD- and NAFLD-HCC seen since 2015

FDA Approval of New COVID-19 Boosters Could Come by Friday

The new booster targets the XBB.1.5 omicron subvariant, which is similar to the dominant variant now circulating

Early-Onset Cancer Morbidity Continuing to Increase

Main risk factors underlying early-onset cancers are dietary risk factors, alcohol consumption, and tobacco use

Opioid-Free Discharge Feasible After Pancreatectomy

In a recent study, there was an increase in the percentage of patients discharged opioid-free

Eye Tracking of Social Visual Engagement Predicts Autism Diagnosis

Findings seen among 16- to 30-month-old children referred to specialty autism clinics

In Situ, Invasive Melanoma Diagnoses Decreased in 2020

Significant decrease seen in incidence of stage I melanomas but not other stages

Cannabis Legalization, Commercialization Linked to Traffic Injuries

Threefold increase reported in quarterly rate of cannabis-involved traffic injury ED visits during commercialization

ADHD Is Independent Risk Factor for Psychiatric Disorders

Independent association seen for genetic liability to ADHD with risk for anorexia nervosa; bidirectional link noted to major depressive disorder

No Change Seen in Frequency of Recurrent Vertigo Attacks Over Time

Attack frequency did not change over three years for people with benign recurrent vertigo, Meniere disease, or vestibular migraine

Early Clean Intermittent Catheterization Recommended With Neurogenic Bladder

High-grade vesicoureteral reflux is crucial risk factor for recurrent febrile urinary tract infections in children

Statin Use Linked to Reduced Risk for CRC Incidence, Mortality in Patients With IBD

Benefit for incident CRC was duration-dependent, with significantly reduced risk after two or more years of use

DOACs Reduce Dementia Risk Versus Warfarin in A-Fib

Significant reductions were seen in dementia risk for rivaroxaban, apixaban, and dabigatran versus warfarin in network meta-analysis

Traumatic Brain Injury Linked to Cognitive Decline in Twin Study

History of TBI, TBI with loss of consciousness, older-age TBI linked to lower cognitive scores at age 70 years

Atezolizumab Can Induce Response in Alveolar Soft Part Sarcoma

Anti-PD-L1 agent induces sustained responses seen in about one-third of patients with advanced alveolar soft part sarcoma

Panel of 48 CSF Proteins Complements Existing Alzheimer Biomarkers

CSF 48 panel plus existing biomarkers significantly improved diagnostic performance for outcomes studied

Revisional-RYGB Examined for GERD and Weight-Loss Failure

Almost all patients had remission of reflux symptoms after R-RYGB following sleeve gastrectomy

Urinary Biomarkers Can Differentiate IC/BPS From Other LUTDs

Urinary TNF-α and eotaxin levels can differentiate interstitial cystitis/bladder pain syndrome from other dysfunctions in men

Clinical Severity Staging System May Aid Tx Selection for Meniere Disease

Decreased vertigo severity, comorbidity burden, and absence of hearing loss tied to conservative treatment response

Decrease in U.S. Preterm Mortality Seen in Recent Decades

Relative risk for preterm mortality widened over time for nonsmokers, those with high levels of education

Availability of CVD Meds Varies by Low-Cost Generic Program

Variation in coverage seen by program, drug, and cardiovascular disease condition

CDC Warns of Rise in RSV Cases Among Young Children, Infants

Spike in severe cases seen in Florida and Georgia; regional increases usually predict the beginning of RSV season, according to CDC

CDC: Warm Waters Raise Risk for Flesh-Eating Bacteria

Infections have been mostly seen in Gulf Coast states; infections in the Eastern United States have increased eightfold from 1988 to 2018

Moderna Says Updated COVID-19 Vaccine Shields Against Highly Mutated New Variant

Scientists found the variant appears to be less concerning than initially thought, with data showing it is 60 percent less infectious than XBB.1.5 variants

Obesity-Linked CV Mortality Increased From 1999 to 2020

Highest age-adjusted mortality rates seen for Black individuals, and greatest temporal increase found in American Indian and Alaska Native individuals

Overdose Deaths Involving Counterfeit Pills Increasing in U.S.

Quarterly percentage of deaths more than doubled with evidence of counterfeit pill use from July to September 2019 to October to December 2021

Fewer Complications Seen With Vitamin C, D Supplementation in AML

Overall survival did not differ, but significant interaction found between supplementation and NPM1 with survival

Diagnostic Performance of AI Comparable to Humans for Mammograms

Diagnostic performance comparable for two test sets from the Personal Performance in Mammographic Screening scheme

OOP Costs Often Exceed Discount Card Pricing for Select Generics

OOP payments exceeded Amazon and GoodRx prices for 40 and 79 percent of prescriptions assumed to be in deductible phase

In-Hospital Adverse Events Similar for Haloperidol, Atypical Antipsychotics

Comparable rates of in-hospital adverse events seen among seniors prescribed oral antipsychotics after major surgery

Major Discharge Barriers Present for One in 10 Hospitalized Patients

Prolonged length of stay is often due to need for skilled therapy or daily living support in medically ready patients

Infertility Tx Tied to Higher Risk for Stroke Hospitalization

Risk for stroke hospitalization within 12 months of delivery higher for those who received infertility treatment versus spontaneous conception

Sleep Apnea Treatment Cuts Nighttime Heartburn, Respiratory Symptoms

Positive airway pressure treatment itself associated with less wheezing

Chronic Traumatic Encephalopathy Seen in Young, Deceased Athletes

However, clinical correlates of pathologic brain conditions are still uncertain

Cannabis May Be Tied to Increased Risk for Psychiatric Outcomes

However, cannabis and cannabis-based medicines may aid certain clinical conditions

Apixaban Has Lower Bleeding Risk for Initial Anticoagulation for Venous Thromboembolism

During extended treatment, bleeding risk was similar for apixaban and rivaroxaban

Smoking Increases Risk for Mental Illness

Smoking increased the risk for being hospitalized with a mental illness by 250 percent

More Than One in Four Older Adults Report Falling in the Previous Year

Self-reported falls more common in women, but fall-related deaths more common in men

Half as Many Internal Medicine Residents Pursuing General Internal Medicine

Simultaneously from 2009-2011 to 2019-2021, interest in hospital medicine gained popularity

Most of the Effect of Paroxetine for Treating Hot Flashes May Be Placebo Effect

Authors say mean treatment effect for hot flash frequency may only be 21 percent

EASD: Low-Dose Aspirin Tied to Lower Risk for New Diabetes in Older Adults

Findings show low-dose aspirin also slows the increase in fasting plasma glucose over time among initially healthy older adults

Overactive Bladder Symptoms Common With Pelvic Organ Prolapse

Just over one-third of women experienced improvement in symptoms across treatment modalities

Alterations in Infant Gut Microbiota Precede Development of Eczema

Similar patterns also observed in C-section-born infants

Mitotane Not Needed With Low- to Intermediate-Risk Adrenocortical Carcinoma

No significant improvement seen for relapse, but treatment was associated with side effects

Psilocybin Tied to Fewer Symptoms With Major Depressive Disorder

Significant benefit seen as early as eight days compared with placebo

Young Smokers Report More Ocular Symptoms

Teen, young adult users of e-cigarettes and cigarettes more likely to have severe, frequent ocular symptoms

Higher Administrative Payment Burden Causes Delays in Cancer Care

Younger patients, African American patients appear to have more cost-related delays/nonadherence

Erectile Dysfunction May Be Marker for Prediabetes, Diabetes

Authors urge glycemia screening in younger men presenting with ED

Marijuana Users Have Higher Metal Levels in Blood, Urine

Cadmium and lead levels significantly higher among exclusive marijuana users

Gut Microbiome May Predict Later Peanut Allergies

Infants who eventually developed peanut allergies had lower gut microbiome diversity during their early years

Federal Government to Regulate Staffing at Nursing Homes for First Time

Proposal would set minimum staffing to equivalent of three hours per resident per day, with just over a half hour of that time from a registered nurse

Factors ID’d That Increase Risk for Mechanical Ventilation With Sepsis

However, risk factors change depending on time from diagnosis and comorbidities

Psychosocial Stressors Tied to Incident Atrial Fibrillation in Postmenopausal Women

Analysis revealed two clusters of highly correlated psychosocial factors -- stress and strain

Female Surgeons Have Lower Rates of Adverse Postoperative Outcomes

Findings persist for common surgeries when accounting for patient, procedure, surgeon, and other characteristics

Concizumab May Be Effective Prophylaxis for Hemophilia A or B With Inhibitors

Overall median annualized bleeding rate was 0 with concizumab

Drinking Water Quality Tied to Lung Infections in Patients With Cystic Fibrosis

High levels of sulfate, vanadium, molybdenum in water supplies may increase the risk for nontuberculous mycobacteria pulmonary infections

Even Five Years Postapproval, Many Drug Studies Remain Nonpublic

Authors urge greater transparency of study results for drugs approved by the FDA

Rates of Tx Retention for Rifaximin Low Despite Benefits for Hepatic Encephalopathy

Lower treatment retention rates seen with 30-day, out-of-pocket costs ≥$150

Warning Symptoms May Predict Sudden Cardiac Arrest

Warning symptoms differed significantly between patients with sudden cardiac arrest and controls, but were sex-specific

Zolbetuximab Plus CAPOX Beneficial for Advanced mG/GEJ Adenocarcinoma

Progression-free survival and overall survival prolonged with zolbetuximab plus CAPOX versus placebo plus CAPOX

Patient Experience Scores for Hospital Care Decreased During COVID-19

Higher-performing and higher-staffed hospitals prepandemic were slower to decline, but all declined by Q4 of 2021

Prostate-Specific Antigen Levels Posttreatment May Not Predict Overall Survival

Biochemical recurrence does not meet the criteria to be a reliable surrogate endpoint for overall survival

Delays in Endometriosis Diagnosis Tied to Increased Health Care Utilization

Increased health care utilization seen up to 10 years before diagnosis with increases closer to diagnosis

Atopic Dermatitis Increases Risk for Inflammatory Bowel Disease

Risk varies by age, atopic dermatitis severity, and inflammatory bowel disease subtype

Tech ‘Glitch’ Causing Children to Lose Medicaid Coverage

Automated systems involved in large-scale eligibility review are causing entire households to be removed from Medicaid coverage, but children may still be eligible

Marijuana Should Be Moved to Lower-Risk Drug Category, U.S. Health Officials Say

The move would not legalize marijuana, but could move it from its Schedule I classification to a Schedule III

Tx of Postnatal Depression Tied to Better Maternal, Offspring Outcomes

Selective serotonin reuptake inhibitor treatment tied to lower risk for maternal mental health problems and child externalizing behaviors across early childhood

Omega-3, -6 Fatty Acids No Aid for Vision Among Extremely Preterm Infants

Findings seen for visual acuity at 2.5 years of corrected age, but authors note that high loss to follow-up rate may have impacted findings

Subcutaneous Securement System Best for Reaching End of PICC Need

Subcutaneous anchor securement system better than adhesive securement device for reaching end of need with a single PICC

Mortality Lower for Patients With Obesity and ARDS Receiving ECMO

ICU mortality lower compared with patients without obesity in multivariable and propensity score-matched analyses

Recurrent Injury, Death Common After Acute Firearm Injury

Individuals experiencing recurrent injury are typically young and mostly male, Black, and uninsured

ESC: Cumulative Sedentary Time in Younger Years Tied to Changes in Heart Structure

13-year findings reveal sedentary time from childhood through young adulthood associated with progressive left ventricular remodeling

Overestimation of Oxygen Saturation Leads to Delayed COVID-19 Treatment

Patients with unrecognized need for COVID-19 therapy appear to have higher odds of readmission, regardless of race

Mortality Risk Increased for Six Months After COVID-19 in Veterans

Those who survived COVID-19 had reduced mortality on days 181 to 365 and 366 to 730

Statin Exposure Not Linked to Increased Risk for Recurrent ICH

Survivors of spontaneous intracerebral hemorrhage with statin exposure have a lower risk for any stroke, ischemic stroke

Total Hip Arthroplasty Can Be Performed Safely in 90-Year-Olds

Comorbidities tied to higher rates of complications and postoperative morbidity

Some Immunosuppressed Do Not Have Anti-Spike Antibodies After COVID-19 Vaccination

IgG anti-spike antibodies undetectable in ~20 percent with immunosuppression who had received three or more COVID-19 vaccines

Hospital COVID-19 Burden Impacted NSTEMI Treatment, Outcome

Outcomes and treatment worse for patients hospitalized during weeks with a high hospital COVID-19 burden

Surgery for Isolate Cleft Palate at 6 Months Yields Better Outcomes Than at 12...

Benefits seen for velopharyngeal insufficiency at 5 years of age

No Change in Depression Seen in Children Across the Globe From 2004 to 2019

Findings based on 41 studies with data for children younger than 13 years old

Many Heart Attack, Stroke Survivors Do Not Know Their Cholesterol Levels

American Heart Association says knowing levels is key to preventing recurrent heart attack, stroke

Narcan Will Reach Drug Store Shelves Next Week

The nasal spray version of naloxone will be available at select retailers for $44.99 for a box of two doses

Adult Education Classes May Lower Dementia Risk

Additionally, participation tied to greater retention of subsequent fluid intelligence

ESC: Catheter Ablation Aids Symptomatic Atrial Fibrillation, End-Stage Heart Failure

Patient benefits seen for all-cause mortality, implantation of a left ventricular assist device, or urgent heart transplantation

Women’s Weight Loss Tied to Lower Odds of Living to 90 Years or Older

Three-year weight loss in older women tied to 33 percent lower odds of reaching age 90 years; association stronger for unintentional versus intentional weight loss

Higher Neighborhood Opportunity Tied to Lower Childhood Asthma Incidence

However, no association seen for social vulnerability index in early-life neighborhood