Alzheimer Disease Tied to Adverse Financial Events

Adverse financial events seen years before diagnosis and become more prevalent after diagnosis

‘Teach-Back’ Communication Strategy Aids Diabetes Outcomes

Patients who use teach-back have fewer diabetes-related complications, hospitalizations, health expenditures

Increased PCR Testing Shown to Slow COVID-19 Transmission

Average reproduction number reduced by 9 percent with 10-fold increase in ratio of tests to new cases

Antiviral Drugs Have No Effect on Mortality in COVID-19

Remdesivir, hydroxychloroquine, lopinavir, interferon regimens have little to no effect on in-hospital mortality

Ongoing Anticoagulant Use Does Not Avert Severe COVID-19

No reduction seen in risks for hospital admission, intensive care unit admission, or death due to COVID

Black Men Experience More Treatment Regret With Prostate Cancer

Higher medical mistrust and concerns about masculinity may contribute to regret

Emergency Departments Saw Decrease in All Non-COVID-19 Diagnoses

Related decreases seen for specialty consultation and urgent inpatient procedures

Large Increase Seen in Overdose-Related Cardiac Arrests in COVID-19

Overdose-related cardiac arrests sharply increased during April 2020, followed by subsequent decrease

Good Outcomes Reported With Single-Position Lumbar Surgery

Operative time, estimated blood loss, length of stay, fluoroscopy radiation dosage reduced with SPLS versus 'Flip'

Residential Care Community Characteristics Vary by Dementia Prevalence

Higher prevalence of depression, need for assistance with activities of daily living seen for high proportion of residents with dementia

Pembrolizumab Slows MSI-H-dMMR Metastatic CRC

Pembrolizumab superior to chemo for progression-free survival among patients who had not previously received treatment

Gestational Age at Birth Tied to Hospitalizations to Age 10

Children born <28 weeks had highest rate of hospital admission; risk also up for children born at 38 weeks

Dexamethasone May Hinder Immunotherapy for Glioblastoma

Findings seen in preclinical studies of mice, survival data from patients receiving PD-(L)1 blockade for GBM

Federal Rules Tied to Reduced ED Visits for Pediatric Magnet Ingestions

Tighter industry regulation tied to fewer emergency department visits, while lack of rules tied to more visits

More Long-Term Dialysis Patients Aligned to ACOs

Among Medicare beneficiaries on dialysis, less spent per beneficiary-quarter for ACO-aligned versus nonaligned

Mental Health Symptoms Common for Perinatal Women During COVID-19

Women with preexisting mental health diagnoses more likely to have mental health symptoms during pandemic

Sedentary Behavior Linked to Heart Failure Hospitalization

Risk for heart failure hospitalization in postmenopausal women increased with sitting, sedentary behavior

Everyone Who Gets COVID-19 Vaccine Will Receive Vaccination Card

Wallet-sized card will document what dose has been given and when next dose is due

Menopausal Symptoms Tied to Lower Work Performance

Women reporting more symptoms also had more chronic diseases, less exercise

Teens Still Able to Access E-Cigarettes During COVID-19 Pandemic

Some report changing their point-of-purchase to access products during the pandemic

RSNA: Deep Learning Model Can Predict Breast Cancer Risk

DL model using screening mammography biomarkers can improve accuracy for predicting future breast cancer risk

SARS-CoV-2 Seroprevalence Low in U.S. From July to Sept. 2020

Jurisdiction-level seroprevalence varied from less than 1 percent to 23 percent across four collection periods

CDC Director Warns of Dire Winter Ahead for COVID-19 Hospitalizations, Deaths

Redfield says that the coming winter months are going to be 'the most difficult time in the public health history of this nation'

FDA Approves Drug for PET Imaging of Prostate Cancer

Approval of Gallium 68 PSMA-11 provides new imaging approach to detect prostate cancer metastasis or recurrence

Parosmia Tied to Smell Recovery After Olfactory Training

Parosmia linked to clinically relevant recovery in patients with postinfectious smell loss receiving olfactory training

Statin Use for Primary Prevention of CVD Lower for Sexual Minorities

Lesbian, gay, bisexual population less likely to use statins in analyses adjusted for covariates

Rate of Cancer in Teens, Young Adults Increased From 1973 to 2015

Greatest rate of increase seen for kidney carcinoma in male, female adolescents and young adults

RSNA: Sleeve Gastrectomy in Teens May Harm Bone Health

Decrease in lumbar volumetric bone mineral density seen in obese teens undergoing sleeve gastrectomy

More Than One-Third of Children With SARS-CoV-2 Are Asymptomatic

Cough, rhinorrhea not predictive of positive test; anosmia/ageusia, nausea/vomiting, headache, fever were most predictive

Admission Hyperglycemia Predicts Mortality in COVID-19

Patients with hyperglycemia had higher cumulative probability of mortality, independent of preexisting diabetes

Atrial Pathophysiology Differs in Black, White Stroke Patients

Black race associated with smaller left atrial diameter, greater P-wave terminal force in ECG lead V1

Circulating Metabolites Linked to Risk for Incident Stroke

10 significant metabolite associations identified, including amino acid histidine, glycolysis-related metabolite pyruvate

Risk for Fatal Cardiovascular Events High in Many T2DM Patients

More than one-third of T2DM patients without established cardiovascular disease had very high risk for CV events

AMA Pushes for Widespread Telehealth Adoption

American Medical Association House of Delegates will advocate for equitable and accessible telehealth post-COVID-19

CDC Shrinks COVID-19 Quarantine Time, Advises Against Holiday Travel

New quarantine guidelines allow people who have come in contact with someone infected with the virus to resume normal activity after 10 days

Female Doctors Less Likely to Be Promoted to Upper Faculty Ranks

Sex differences in promotions and appointments did not diminish over time and were not smaller in later cohorts

Boosting Coverage of Midwife Care Could Avert Deaths

About two-thirds of maternal deaths, neonatal deaths, stillbirths could be averted with universal coverage of midwife-delivered interventions

Anxiety Doubled in Young People During COVID-19 Pandemic

Number of young adults reporting anxiety doubled and was higher than that of their parents

Britain Approves Emergency Use of Pfizer COVID-19 Vaccine

FDA advisory panel to meet on Dec. 10 to decide whether agency should grant emergency use authorization to the vaccine

Tanning Bed Use by Young Women May Up Endometriosis Risk

Number of sunburns during adolescence, percentage of time using sunscreen in adulthood positively linked to endometriosis

Admission for SARS-CoV-2 Down With Prior Metabolic Surgery

Obese patients with COVID-19 who had prior metabolic surgery and subsequent weight loss have reduced rates of hospital admission

Chilblain-Like Lesions During COVID-19 Tied to Type I Interferonopathy

Findings based on systematic clinical, histologic, and biologic assessment

Diabetic Retinopathy May Up Risk for COVID-19 Intubation

In adjusted analyses, retinopathy independently and significantly associated with more than fivefold higher risk for intubation

Review: Thromboembolism Risk High in COVID-19 Patients

Patients with thromboembolism have increased pooled odds of mortality compared to those without

Women at Increased Risk for Heart Failure, Death After MI

Women had higher unadjusted rate of in-hospital mortality than men after first-time STEMI, NSTEMI

Women Have Lower Risk for Death After Resection for Lung Cancer

Restricted mean survival time difference was 0.84 years at 10 years for women undergoing pulmonary resection

Risk for SARS-CoV-2 Infection Lower for O, Rh− Blood Groups

Also, risk for severe COVID-19 illness or death lower for O versus all other groups, for Rh− versus Rh+

Industry Payments Consistently Linked to Physician Prescribing

Thirty of 36 studies identified a positive association between payments and prescribing in all analyses

Smoking Prevalence High Among Adults With Active, Inactive Epilepsy

Health care personnel should ensure patients with epilepsy are provided with smoking cessation information and resources

Higher Doses of Z-Drugs Pose Risks for Dementia Patients

Risks for fracture, falls, ischemic stroke increased in patients with dementia prescribed higher doses of Z-drugs

WHO: Strawberry-Flavored HIV Medication Coming for Infants

WHO has also approved the dapivirine ring, a vaginal insert that has shown to be effective in protecting against HIV in women

Patient Expectations for Lumbar Surgery Often Too High

Surgeons more accurate at predicting two-year follow-up outcomes

Green Mediterranean Diet May Be Even Healthier

Decrease in waist circumference greater than with traditional Mediterranean diet or healthy dietary guidance

Mortality Rate High With Frequent Alcohol-Linked ED Visits

Individuals with five or more visits have higher adjusted mortality rate than those with two visits per year

Prognosis Good With Negative Biopsy in Active Surveillance

Negative biopsies during active surveillance for low-risk prostate cancer tied to more favorable outcomes

Racial Disparity Seen in COVID-19 Multisystem Inflammatory Syndrome

Rates more than three times higher in Black children in New York City versus White children

Breast Cancer, CRC Incidence No Different With, Without MS

However, bladder cancer incidence and mortality rates higher among individuals with multiple sclerosis

First Blood Test for Alzheimer Disease Available in U.S.

Test from C2N Diagnostics is meant for people 60 years and older who have cognitive issues and are being assessed for Alzheimer disease

Canagliflozin Beneficial Even for Advanced Kidney Disease

Canagliflozin slows progression of kidney disease in participants with eGFR <30 mL/min/1.73 m2 with no increase in AKI

Adverse Pregnancy Outcomes Up for Women With Psoriasis

Odds ratios increased for preeclampsia, severe postpartum hemorrhage, stillbirth, SGA, preterm labor

ART Treatment Not Tied to Higher Risk for Ovarian Cancer

Increased risk compared with general population likely due to nulliparity among ART-treated women; risk not increased versus subfertile women

Colon Cancer Diagnosed Earlier Under Medicaid Expansion

Medicaid expansion also may result in improved access to treatment, including palliative care

CVD Risk Higher in T2DM Even With Optimal Risk Factor Management

Those with T2DM with optimal risk factor control have greater risk for cardiovascular disease events versus those without T2DM

Cardiorespiratory Fitness Reduced With Prolonged ADT in Prostate Cancer

Increased cardiovascular mortality also seen with prolonged androgen deprivation therapy for prostate cancer

Risk for Bone Fractures Up for Patients With Psoriatic Diseases

No difference in bone mineral density and no increased risk for osteoporosis seen for psoriatic disease patients versus controls

Decline in SARS-CoV-2 Antibody Response Seen Over 60 Days

More than one in four health care personnel who were positive for SARS-CoV-2 antibodies were seronegative on repeat testing

Moderna to Request Emergency Approval for COVID-19 Vaccine

The company's application is based on data showing that the vaccine has met the necessary scientific criteria

COVID-19 Outcomes Not Improved With Convalescent Plasma

Clinical status, mortality did not differ for convalescent plasma versus placebo in adults with severe COVID-19 pneumonia

CT Use Down for ED Evaluation of Abdominal Pain in Children

Among adults with abdominal pain, use of CT in emergency department consistently increased from 1997 to 2016

Fauci Calls for Americans to Pull Together, Says ‘Help Is on the Way’

Anthony Fauci, M.D., spoke with HD Live! about the safety and efficacy of a COVID-19 vaccine and doubling down on efforts to stop the surge in cases

2016 to 2019 Saw Increase in Prepregnancy Obesity in U.S.

Increase seen across women of all ages, Hispanic origin groups, educational levels

USPSTF Urges Behavioral Counseling to Reduce CVD Risk

Behavioral counseling interventions to promote healthy diet and physical activity have moderate net benefit

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Predictors of Satisfaction With RYGB Over Seven Years Identified

And, physical activity associated with improvements in depression and mental and physical HRQoL after RYGB

RSNA: Anxiety May Hasten Progression to Alzheimer Disease

Rate of progression from MCI to AD increased with ApoE4, anxiety, lower hippocampal and entorhinal cortex volumes

AI Algorithm Can Detect COVID-19 on Chest X-Rays

Accuracy of 82 percent achieved with DeepCOVID-XR compared with 81 percent for consensus of five thoracic radiologists

U.S. COVID-19 Vaccine Distribution Could Begin in Mid-December

Vaccine appears 95 percent effective at preventing mild-to-severe COVID-19, according to the manufacturers

Delirium Common in Seniors Presenting to ED With COVID-19

Delirium is the sixth most common presenting symptom/sign; delirium linked to ICU stay and death

Purdue Pharma Pleads Guilty Over Role in U.S. Opioid Epidemic

Company admits paying doctors to write more prescriptions, providing misleading information to the DEA

Hormonal Contraceptives Linked to Decline in Asthma Exacerbation

Risk reduced with previous and current use of any and combined hormonal contraceptives, not with progestogen-only use

Job Changes Increasingly Common Among U.S. Radiologists

Practice separation most common among early- and late-career radiologists, general radiologists

AHA: Ablation Better Than Meds for Initial A-Fib Treatment

Findings based on randomized trial evaluating initial treatment with cryoballoon catheter ablation versus standard meds

AHA: Sotagliflozin Beneficial for T2DM With Heart Failure

Second study shows benefits among patients with type 2 diabetes and chronic kidney disease, risks for CVD

Many Infants With Hep C-Positive Moms Not Screened for HCV

Prenatal care is an important time to screen for hepatitis C, authors say

Xofluza Approved for Postexposure Prevention of Flu

Influenza infection and symptoms occurred in 1 and 13 percent of those receiving Xofluza and placebo, respectively

CDC Recommends Three COVID-19 Tests for Americans Traveling Abroad

Tests recommended one to three days before the flight, three to five days after the flight, and one to three days before returning

Mediterranean Diet Cuts Type 2 Diabetes Risk in Women

Risk reduction driven by improvement in insulin resistance, lipoprotein metabolism, and inflammation

First Drug Approved to Treat Rare Metabolic Disorder

Oxlumo granted approval to treat primary hyperoxaluria type 1

CDC Warns That COVID-19 Vaccine Might Spur Transient Sickness

Some volunteers in trials of candidate vaccines have reported flu-like symptoms after immunization

SARS-CoV-2 Infection Rates Generally Low in U.S. Children

Black, Hispanic, Asian children less likely to get tested for SARS-CoV-2, more likely to test positive than White children

RSNA: Neurologic Complications of COVID-19 Examined

In patients with critical findings identified on neuroimaging, most common comorbidities were hypertension, diabetes

BCG Vaccination Linked to Lower SARS-CoV-2 Seroprevalence

Seroprevalence of anti-SARS-CoV-2 IgG lower for health care workers with history of BCG vaccination

COVID-19 Infection Not Tied to Adverse Pregnancy Outcomes

7 percent of mothers delivering at large county health system tested positive, as did 3 percent of tested infants

AHA: Obese Patients More Likely to Be Hospitalized for COVID-19

Risk for in-hospital death, mechanical ventilation higher for obese patients; link between BMI and outcomes strongest for adults ≥50 years

AHA: Out-of-Hospital Cardiac Arrest Outcomes Worse During COVID-19

OHCA outcomes worse early in the pandemic even in areas with low case-fatality rates

ATS Issues Guideline on Home Oxygen Therapy for COPD, ILD

Long-term oxygen therapy strongly recommended for adults with COPD, ILD who have severe chronic resting hypoxemia

Rural, Urban Disparities Seen for New Liver Cancer Cases

New hepatocellular carcinoma cases highest among rural Hispanic residents

Non-COVID-19-Related Deaths Up, Too

Excess deaths seen for specific gender and age groups, with protective effect seen for female children

Contraceptive Use Low Among Women With Kidney Disease

Overall rate of contraceptive use 5.3 percent of person-years

FDA Authorizes Use of Monoclonal Antibody Treatment for COVID-19

IV infusion of casirivimab and imdevimab authorized for treatment of mild-to-moderate COVID-19

Chimpanzee Adenovirus COVID-19 Vaccine Promising in Seniors

Immunogenicity similar across age groups; vaccine better tolerated in older versus younger adults

WHO: Remdesivir Not Advised for Hospitalized COVID-19 Patients

Evidence to date has not shown clinically important effects on mortality, need for mechanical ventilation

Third COVID-19 Vaccine Shows Effectiveness

The AstraZeneca vaccine becomes the third to show good effectiveness

AHA: Blacks, Hispanics Make Up 53 Percent of COVID-19 Deaths

Mortality, MACE rates among patients hospitalized with COVID-19 did not differ by race, ethnicity

Cirrhosis Cases Rising Among Women in North America

Projected future increases in cirrhosis due to alcohol-related liver disease and nonalcoholic fatty liver disease

Early ECMO-Facilitated Resuscitation Ups Survival in OHCA

Findings seen among adults with out-of-hospital cardiac arrest and refractory ventricular fibrillation

AHA: Care for Type 2 Myocardial Infarction Patients Varies

Just over half of patients with type 2 MI seen by a cardiologist in hospital; most did not see a cardiologist for follow-up care

Cognitive Exercises May Lower Risk for Postoperative Delirium

Cognitive prehabilitation reduced delirium among older adults undergoing major noncardiac surgery

FDA-Authorized Alpha-Defensin Lateral Flow Test Highly Accurate

Test demonstrates good performance for rapid diagnosis of periprosthetic joint infection around joint implants

Predictors of Late Effects in Young AML Survivors Explored

Most common late effects were endocrine, cardiovascular, respiratory; likelihood of late effects up for those who underwent HSCT

Vegans Have Increased Risk for Total, Main-Site Fractures

Association attenuated slightly with adjustment for dietary calcium and/or protein but still significant

Social Needs Linked to Lower HRQOL for Black Cancer Survivors

More than one-third of cancer survivors reported social needs, with highest prevalence for food insecurity

AHA Meeting Addresses Latest Research, COVID-19, Health Care Disparities

American Heart Association President-Elect Donald Lloyd-Jones, M.D., discussed highlights of the AHA Scientific Sessions 2020 with HD Live!

Less Than One in 20 Eligible Adults Receives Lung Cancer Screening

Lung cancer screening at the state level does not correlate with lung cancer burden

U.S. Nephrology Trainees Doubt Skill in Home Hemodialysis

Most respondents report being moderately confident about principles of peritoneal dialysis, but few had initiated urgent-start PD

FDA Issues EUA to Baricitinib Plus Remdesivir for COVID-19

Emergency use authorization applies to hospitalized patients requiring supplemental oxygen, mechanical ventilation, ECMO

ALA: Lung Cancer Survival Has Increased Nationally to 22.6 Percent

People of color face worse outcomes, have lower likelihood of being diagnosed early, receiving surgery

High-Dose Anticoagulation May Not Aid COVID-19 Patients

No significant benefit seen for high-dose versus standard anticoagulation therapies, may be harmful

Behavioral, Psych Condition Care Shifted to Telemedicine During COVID-19

Office-based visits decreased from before 2020 to during pandemic, but telemedicine visits increased in 2020 Q1, Q2

Biopsy Reclassification Risk in Prostate Cancer Examined

Gleason grade, prostate-specific antigen velocity, and imaging markers predict cancer spread

Risk for Infection Up for Children Born by C-Section

Increased risk for serious childhood infection following elective, emergency cesarean section persisted to five years

Rates of VTE, Major Bleeding High in Primary CNS Lymphoma

Pulmonary embolism and major bleeding linked to increased mortality risk

Air Pollution May Up Alzheimer Disease Risk in Elderly

Association seen in older women persisted even at PM2.5 levels below U.S. regulatory standards

Preoperative Mental State Associated With Postoperative Pain

Presurgery depression, anxiety, catastrophizing tied to more pain after joint replacement surgery

Greater Social Support Tied to Lower Diabetes-Related Distress

Specifically, perceived support of family members significantly tied to less distress among low-income patients

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

CDC: About One in Five U.S. Adults Reports Tobacco Product Use

Prevalence of any current tobacco product use up for men; adults aged ≤65 years; lesbian, gay, bisexual adults

Teens Increasingly Worried About Their Weight

Large U.K. study shows more teens are dieting, overestimating their weight

COVID-19-Related Job Insecurity Tied to Anxiety, Depression

Survey of nearly 5,000 young adults reveals link between job insecurity and self-reported anxiety, depression

Wrong-Patient Order Entry Errors Reduced With Patient Photos

Display of patient photographs in electronic health records associated with decrease in WPOE errors

TAVR Volumes in the U.S. Have Risen Each Year Since 2011

In 2019, TAVR exceeded surgical procedures; 30-day mortality and stroke rates decreased since 2011

AHA: Adding Omega-3 Fatty Acids Does Not Cut High CV Risk

No reduction seen in CV events with omega-3 versus corn oil in addition to usual background therapies, including statins

Medicaid Expansion Tied to Increased Detection of Early Cancers

Three years after expansion, a decrease in late-stage cancers was also detectable

U.S. COVID-19 Deaths Top a Quarter Million

COVID-19 cases on the rise in all but one state

Disproportionality Signal Found for Suicidality in Finasteride Users

Younger patients and those with alopecia have significant disproportionality signals for increased suicidality

Group-Based Lifestyle Intervention Cuts Progression to T2DM

High-risk individuals making modest changes in weight, physical activity had lower odds of progressing to type 2 diabetes

2009 to 2018 Saw Increase in Incidence of NAFLD in Children

12.3 percent of obese and overweight children with alanine aminotransferase >30 U/L received further workup for NAFLD

Lorlatinib Superior to Crizotinib for ALK-Positive NSCLC

Interim analysis shows risk for disease progression or death lower for first-line therapy with lorlatinib versus crizotinib

Hearing Test Response May ID Newborns at Risk for Autism

Prolonged auditory brainstem response phase, V-negative latency seen in newborns with autism spectrum disorder

2010 to 2018 Saw Decrease in Rate of Death for People With HIV

48.4 percent decrease found in HIV-related death rates and 8.6 percent decrease seen in non-HIV-related death rate

AI Model May Predict Immunotherapy Response in Melanoma

Histology slides, clinical data used to predict immune checkpoint inhibitor response in advanced melanoma

Predictors of Severe Disease ID’d in Children With SARS-CoV-2

Obesity and hypoxia on admission predictive of severe respiratory disease; children with MIS-C more likely to be non-Hispanic Black

Highest Maternal Mortality Rate Seen in United States

United States is only country not to guarantee access to provider home visits or paid parental leave in postpartum period

Vitamin D Supplementation Tied to Reduction in Advanced Cancer

On stratification by BMI, significant reduction found in incident metastatic or fatal cancer in normal weight, not overweight/obese

Fluvoxamine Linked to Reduction in Clinical Deterioration in COVID-19

Findings seen among adult outpatients with SARS-CoV-2 with oxygen saturation of 92 percent or greater

Ebola Outbreak in Democratic Republic of the Congo Declared Over

Wednesday marks 42 days, or two incubation periods, since the last survivor tested negative for the virus

AAP Urges Inclusion of Children in SARS-CoV-2 Vaccine Trials

AAP joins six other medical groups in letter requesting transparency and communication to improve confidence in a vaccine

Hormonal Contraceptive Use May Delay Return of Fecundability

Longest delay of five to eight months found for users of injectable contraceptives; no lasting effect seen on fecundability for long-term use

Permanent Night Shift Workers at Higher Risk for Asthma

Increase in risk for moderate-severe asthma observed in morning chronotypes working irregular shifts, including nights

Genetics Tied to Thromboembolism Risk With Inflammatory Bowel Disease

Genetic signature tied to doubled risk for developing potentially fatal blood clots in one in seven IBD patients

Triplet Therapy Slows Refractory Multiple Myeloma

Progression-free survival longer with once-weekly selinexor-containing regimen versus standard bortezomib and dexamethasone

FDA Approves First Rapid COVID-19 Test for Home Use

Simple nasal swab test requires prescription; people younger than 14 cannot perform the test on themselves

AHA: Polypill, With or Without Aspirin, Reduces Cardiovascular Events

Significant reductions seen in primary outcome for use of polypill and polypill plus aspirin combination

Guidelines Developed for Diabetes Management in CKD

Recommendations and practice points relate to comprehensive care needs, glycemic monitoring, lifestyle interventions

Periodontal Pathogens Linked to Atherosclerosis in RA

Immunoreactivity to Aggregatibacter actinomycetemcomitans serotype b, Aa leukotoxin A linked to atherosclerosis

Final Diagnosis Often Differs From Referral Diagnosis for EIS

In 54 percent of children with exercise-induced respiratory symptoms, final diagnosis differed from referral diagnosis

Air Pollution May Affect Mood, Memory in Oldest-Old Women

Indirect effect of remote NO2 and PM2.5 exposure on declines in episodic memory mediated by depressive symptoms

Pandemic Affecting Young People’s Mental Health

Self-reported symptoms of depression, thoughts of suicide much higher than historical norms

Lack of Insurance Tied to Non-Rx Hormone Use in Transgender Adults

Authors say insurance barrier poses risks to safety, health, and well-being

Sixty-Day Outcomes Examined for Hospitalized COVID-19 Patients

29.2 percent died during hospitalization or within 60 days of discharge; ongoing morbidity was common

Persistent Fatigue Prevalent After COVID-19 Infection

More than half of those recovered from acute phase of COVID-19 experience postviral fatigue, independent of COVID-19 severity

2009 to 2018 Saw Increase in Diseases-of-Despair Diagnoses

Increase in alcohol/substance-related diagnoses largest for those aged 55 to 74 years; increase in suicide-related diagnoses largest for under-18s

ACR: Osteoporosis Underdiagnosed, Undertreated in Older Men

Only 2.1 percent of those with qualifying fractures were diagnosed and treated

Routine COVID-19 Testing Improves Safety of Elective Surgery

Benefits of nasal swab testing seen in high-transmission areas and before major surgery

Hospital Mortality Higher for Critically Ill With COVID-19 Versus Flu

Patients with COVID-19 have slower improvement in oxygenation, longer duration of mechanical ventilation, lower rates of extubation

Sedentary Time Increases With Retirement

Abrupt increase in sedentary time seen for women, with more gradual increase for men

Food Insecurity Tied to Higher Cardiovascular Mortality

Findings independent of changes in demographic, economic, and health care access

Major U.S. Medical Groups Urge Trump to Work With Biden on Fighting COVID-19

In letter from three medical associations, the president is urged 'to share critical data and information as soon as possible'

Laparoscopic Resection May Be An Option for CRC Liver Metastases

For resectable colorectal liver metastases, five-year survival rates similar with laparoscopic, open surgery

Antibiotic Therapy Before Age 2 May Affect Child Health

Risk for childhood onset of health conditions increased for those with early-life antibiotic exposure

Nebulized Interferon Beta-1a Promising for COVID-19

Adults hospitalized for COVID-19 receiving SNG001 versus placebo more likely to show clinical improvement

Female Hormone Rx Not Tied to Retinal Vascular Occlusion

No increase seen in risk for occlusion of retinal artery, vein among women filling prescription for female hormone therapy

Asthma EMS Dispatch Rate Down With Insurance Expansion

Asthma EMS dispatch rate in New York City decreased after implementation of the Affordable Care Act

ACR: Warfarin Tied to Increased Risk for Knee, Hip Replacement in OA

Among adults with atrial fibrillation, warfarin use linked to increased odds of knee, hip replacement versus direct oral anticoagulants

AHA: Black Patients Less Likely to Receive Indicated BP Treatment Intensification

This accounts for about a quarter of the total effect on blood pressure control

MI, ASCVD Risk Higher in Older Adults With Elevated LDL-C

And LDL cholesterol-lowering therapies are effective for reducing cardiovascular events in older adults

Diagnostic Radiation May Up Risk for Testicular Cancer

Testicular germ cell tumor risk elevated with exposure to X-ray and CT below the waist, GI series or barium enema

AKI Common in U.S. Veterans Hospitalized With COVID-19

AKI associated with increased odds of mechanical ventilation use, longer hospital stay, increased risk for death

OCD Symptoms Worsening Among Children During COVID-19

Worsening was most pronounced among children with early age of onset, family history of ADHD

Patients Happier With Doctors of Same Race

Authors say findings point to importance of having a diverse physician workforce

Loneliness Tied to Depression in Adults Older Than 50 Years

Between 11 and 18 percent of depression cases could potentially be prevented by eliminating loneliness

SARS-CoV-2 Transmitted Despite Quarantine Conditions

Among Marine Corps recruits, about 2 percent who were negative for SARS-CoV-2 at start of supervised quarantine tested positive by day 14

Pfizer COVID-19 Vaccine Could Cut Transmission by Half: Company Executive

Manufacturers say vaccine is 90 percent effective in protecting people from the new coronavirus

Moderna Vaccine Shows 94.5 Percent Effectiveness Against COVID-19

Company expects to have about 20 million doses of the vaccine ready to ship in the U.S. by the end of the year

Risk for Heart Failure Lower With Healthy Sleep Patterns

Hazard ratio 0.58 for heart failure with healthy sleep score of 5 versus score of 0 or 1

Lung Cancer Tied to Most Potential Years of Life Lost

Potential years of life lost per death highest for deaths due to cancers of testis, bones/joints, other endocrine sites

Interventions to Increase HPV Vaccine Coverage Cost-Effective

Interventions could avert 3,000 to 14,000 future HPV cancers scaling to the U.S. population

ACR Previews New Pharmacotherapy Guidelines for RA

The 2020 Guideline for the Management of Rheumatoid Arthritis updates guidance on drug treatments

Asymptomatic Brain Bleeds in Newborns Not Tied to Long-Term Harm

Normal brain development and neurodevelopmental scores seen at age 2 years

Positive BRCA Test Results Down From 2008 to 2018

Socioeconomic and regional disparities persist in the use of BRCA testing

Mental Health ED Visits in Children Up Mid-March to October 2020

Proportion of mental health-related ED visits increased 24 and 31 percent for children, adolescents

CDC: 26.4 Percent of U.S. Adults With Diabetes Meet ABCS Goals

About one in four meet combined goals of management of blood glucose, BP, non-HDL-C, avoiding smoking

ACR: Corticosteroid Injections Do Not Speed Progression of Knee OA

Rates of radiographic progression similar for corticosteroid injections, hyaluronic acid injections in multivariable analysis

Antipsychotic Use Declined in Young Children From 2009 to 2017

While there was a shift toward evidence-based indications, majority of use remains off-label

Statins Tied to Lower In-Hospital COVID-19 Mortality Risk

For adults hospitalized in Spain with COVID-19, treatment with statins associated with lower COVID-19-related mortality

Breastfeeding Linked to Fewer Behavioral Difficulties for Children

Fewer parent-reported behavioral problems observed with longer duration of breastfeeding