Inflammatory Heart Disease After COVID-19 Rare in Athletes

Five athletes (0.6 percent) had cardiac magnetic resonance imaging findings suggestive of inflammatory heart disease

New Models Predict Risk for Ventilation, Death From COVID-19

Age not a predictor of which hospitalized COVID-19 patients will require ventilation

Tobacco Exposure Tied to Hypertension in Children

Findings based on study of more than 8,500 children ages 8 to 19 years

Erythrocytosis ID’d in 11 Percent of Trans Men Using Testosterone

Factors associated with erythrocytosis include tobacco use, long-acting undecanoate injections, age at initiation of testosterone

Weight Loss Tied to Worse Breast Cancer Outcomes

Baseline body mass index tied to outcomes, with obesity linked to poorer outcome

Timing of Exercise May Be Linked to Cardiovascular Fitness

Associations significant for men with type 2 diabetes, but less so for women

Neurologic Involvement Common in Children Hospitalized With COVID-19

Twelve percent of those with neurologic involvement develop life-threatening conditions associated with COVID-19

FDA Warns Consumers to Not Use Ivermectin for COVID-19

Agency has received reports of patients requiring medical support after self-medicating with ivermectin for use in horses

Globalization of Cancer Trials Tied to Lower Enrollment of Blacks

Significant inverse correlation identified between proportion of patients enrolled outside the U.S. and disparity score

Suicide Decedents in Child Welfare System Had Used Health Services

Young suicide decedents more likely to have accessed mental health services, physical health services; visited ED

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

AI Algorithm May Differentiate Polyps on CT Colonography

Adding machine learning-based image analysis allows noninvasive differentiation of benign and premalignant polyps

Six in 10 Heart Failure Patients Readmitted Within One Year

Comorbidities, including kidney dysfunction, lung disease, and psychiatric illness, tied to higher readmission

Hypertensive Disorders of Pregnancy Tied to Heart Damage 10 Years Later

A decade after delivery, changes seen in left ventricular structure and function

2014 to 2019 Saw Increase in Prevalence of Autism in U.S. Children

From 2014 to 2019, prevalence remained stable among non-Hispanic Whites, while increases were seen in non-Hispanic Blacks, Hispanics

Ivermectin Does Not Speed Symptom Resolution in Mild COVID-19

No significant improvement seen in median time to resolution of symptoms with ivermectin versus placebo

Heart Failure-Related Mortality Up for Rural Versus Urban Adults

Rural-urban incidence rate ratio persisted among younger and older adults after adjustment for county-level factors

Delayed Local Reactions to mRNA-1273 Vaccination Reported

Reactions appeared near injection site at a median onset of day 8 after first dose; six of 12 patients had no recurrence after second dose

Two Cases of SARS-CoV-2 Variant P.1 Identified in Minnesota

Patients reported travel to Brazil within 14 days prior to symptom onset; genome sequencing confirmed specimens to be P.1 variant

Three Modes of Transmission Explain Most Giardiasis Outbreaks

Water exposure, person-to-person contact, contaminated food accounted for more than half of outbreaks in 2012 to 2017

Shortage of Syringes Reported for COVID-19 Shots

Billions poured into development of vaccines, but little public investment made in expanding manufacturing for syringes

Semaglutide May Aid Weight Loss in Obese Patients With T2DM

Estimated change in mean body weight to week 68 was −9.6 percent with semaglutide 2.4 mg versus −3.4 percent with placebo

Ambulatory Function Poorer for Older Cancer Survivors

Poorer ambulatory function associated with increased risks for mortality; significant associations seen for nine cancer types

Psychiatric Visits Increased Significantly in 2020 Versus 2019

7 percent increase found in psychiatric care volume overall, but 42 percent decrease seen for new patients

Frequency of Urgent Vitreoretinal Surgery Down During Pandemic

Decreases seen in intravitreal injections, lasers and cryotherapy, retinal detachment repairs, other vitrectomies

CVD Risk Factors Tied to Cognitive Impairment in Schizophrenia

Significantly greater global cognitive deficits seen in those with schizophrenia who had metabolic syndrome, diabetes, hypertension

Uptake of Seasonal Influenza Vaccine Lower Among Minorities

Uptake lower among Black, Asian, Hispanic adults versus Whites; those vaccinated less likely to receive high-dose vaccine

CV Risk Factors, Atherosclerosis May Alter Brain Metabolism

Cardiovascular risk, particularly hypertension, associated with brain hypometabolism in asymptomatic middle-aged adults

Maternal Cardiovascular Health in Pregnancy Tied to Offspring Cardiovascular Health

Maternal CV health at 28 weeks of gestation tied to offspring cardiovascular health at ages 10 to 14 years

Many Non-Whites Experience Discrimination in Alzheimer Disease Care

Overall, 36, 19, and 18 percent of Black, Hispanic, Asian Americans, respectively, believe discrimination is barrier to receiving care

Egg, Cholesterol Intake Linked to Higher Mortality

Increased mortality associated with egg consumption largely influenced by cholesterol intake

CDC: 21,869 West Nile Virus Cases Identified in U.S. in 2009 to 2018

59 percent were neuroinvasive disease cases, which occurred more often with increasing age

Emptier Roads, but Sharp Rise in U.S. Traffic Deaths Reported in 2020

NHTSA says speed is main problem, as well as increased use of alcohol, marijuana, and opioids

California Targets Vulnerable Neighborhoods for COVID-19 Vaccination

Neighborhoods considered highly vulnerable based on factors such as income, education, housing, and transportation

COVID-19 Death Rates 10 Times Higher in Countries Where Most Are Overweight

Higher BMI also associated with increased risk for hospitalization, ICU admission, need for mechanical ventilation

Pediatric Oncology Services Disrupted During Pandemic

Newly diagnosed pediatric cancer cases decreased in 43 percent of centers; treatment abandonment increased in 34 percent

Traumatic Brain Injury May Increase Risk for Sleep Disorder

Increased risk observed for any sleep disorder, including sleep apnea, insomnia, hypersomnia, sleep-related movement disorder

Premature Ovarian Insufficiency Linked to Osteoporosis

Current cigarette smoking influenced the association, and protective factors included obesity, current hormone therapy use

AAAAI: Peanut Allergy Down 16 Percent in Infants

After 2016 changes to feeding guidelines advising earlier introduction of peanut, prevalence of peanut allergy in infants has decreased

Terlipressin Bests Placebo in Type 1 Hepatorenal Syndrome

Terlipressin is more effective for reversal of HRS but is associated with more adverse events and death due to respiratory disorders

Women With T1DM Experience Shorter Reproductive Period

Women with type 1 diabetes experience 2.5 fewer reproductive years, with findings limited to women diagnosed before reaching menarche

American Indians Have Highest Risk for Nonhemorrhagic Stroke

American Indians have highest risk of nonhemorrhagic stroke compared with non-American Indians, in presence or absence of a-fib

County-Level Factors Affect Race/Ethnicity-Specific CVD Death

Greatest variation in CVD age-adjusted mortality rate explained by socioeconomic factors for non-Hispanic Blacks

New Algorithm Can Predict Advanced Liver Disease

The CIRRhosis Using Standard tests algorithm could use results of routine blood tests to identify those at high risk for advanced liver disease

Nivolumab Plus Cabozantinib Tops Sunitinib for Renal Cell Carcinoma

Combination therapy superior with respect to progression-free, overall survival and overall response for first-line treatment of advanced RCC

Behavioral Health Issues Remain High as Pandemic Continues

Survey results reveal self-reported mental health, substance use, and suicidal ideation among U.S. adults in September 2020

Patients’ Mental Health Impacts Rating of Psoriasis Severity

Likelihood of a patient overestimating their psoriasis severity versus physician increased for those with depression, anxiety

NIH Halts Trial of Convalescent Plasma for Mild COVID-19

While the treatment seemed safe, no significant differences in outcomes were seen between patients receiving convalescent plasma or placebo

USPSTF Urges Screening Young Women for Chlamydia, Gonorrhea

All sexually active women aged 24 years and younger should be screened as well as women older than 25 at high risk

Good Response Seen With HealthCare.gov Reopening

CMS figures show more than 206,000 people signed up for coverage from Feb. 15 to 28

Dysnatremia Tied to Poorer Prognosis in Hospitalized COVID-19 Patients

Hypernatremia linked to increased mortality, while hyponatremia at admission linked to increased odds of needing ventilatory support

Bone Density Testing Low in Veterans With Kidney Stone Disease

23.6 percent of those with kidney stone disease have prevalent diagnosis of osteoporosis or fracture

Costs of Eating Disorders Quantified for the United States

Total economic costs estimated at $64.7 billion for fiscal year 2018 to 2019; reduction in well-being costs estimated at $326.5 billion

AAN: Anomalously Warm Weather Tied to More MS Hospital Visits

Authors say absolute effect on people with multiple sclerosis and the health care system is meaningful

AAN: Antidepressants Not Tied to Increased Intracerebral Hemorrhage Risk

Selective serotonin reuptake inhibitors are not associated with higher risk for intracerebral hemorrhage

Provider Teams Outperform Solo Care for New-Onset Chronic Disease

Among solo providers, there was little difference in care management and outcomes between physicians, nonphysicians

Birth Weight Modifies Link Between Adult IGF-1 Levels, T2DM

IGF-1 levels inversely associated with T2DM risk in dose-dependent manner, but only among those with birth weight ≥2.5 kg

Prediabetes, Type 2 Diabetes Tied to Poorer Brain Health

Higher risk for cognitive decline, vascular dementia, Alzheimer disease seen with high blood glucose

Physical Activity May Cut Fatality Risk in Myocardial Infarction

Risks for instant death, 28-day death related to MI lower in those with moderate-to-high levels of past physical activity

Threshold ID’d for Urine Test to Rule Out Prostate Cancer

In validation study, 3.7 percent of grade group ≥2 cancers missed with MyProstateScore value ≤10

Preliminary Data in Israel Show COVID-19 Vaccines Effectively Prevent Severe Disease

National study shows reduction in ratio of COVID-19 patients requiring mechanical ventilation aged 70 years and older to those younger than 50 years

Umbrella Review Reveals Links Between Diet, Colorectal Cancer

Review of meta-analyses of prospective observational studies reveals lower risk with higher intakes of dietary fiber, dietary calcium, yogurt

Risk for Breast Cancer Death Increased With Missing Mammogram

Serial participants have significantly lower risk for death compared with those who missed one or both of two screenings before diagnosis

One-Third of U.S. Adults Continue to Be Hesitant About COVID-19 Vaccines

Rates of vaccine hesitancy particularly high among Black adults and Republicans, a December survey reveals

Dramatic Decline Seen in COVID-19 Cases, Deaths at U.S. Nursing Homes

82 percent decline reported in new COVID-19 cases among residents at nursing homes since the peak during the week of Dec. 20

Robotically Assisted Surgical Device Authorized for Transvaginal Hysterectomy

Hominis Surgical System granted marketing authorization approval for use in benign hysterectomy with salpingo-oophorectomy

Response to One Dose of COVID-19 Vaccine Strong for Previously Infected

Two studies show higher anti-S titers in those with previous infection and very strong T-cell responses

​IL-6 Receptor Antagonists Benefit Critically Ill With COVID-19​

Improved outcomes, including more organ support-free days, reduced mortality, seen with tocilizumab, sarilumab

Only Two in 10 Older Adults Report Being Screened for Hearing Loss

Half of older adults rate their hearing as excellent or very good

Layperson-Delivered Phone Intervention Eases Loneliness for At-Risk Adults

Reductions seen in loneliness, depression, and anxiety; improvement seen in mental health among at-risk adults

Mortality Lowest With Five Servings of Fruit, Vegetables/Day

Lowest mortality seen with two servings of fruit and three servings of vegetables; no additional risk reduction seen with higher intake

COVID-19 Outcomes No Worse for People With Asthma

Patients with asthma may have a lower risk for becoming infected

Prescription Opioid Misuse Tied to Increased Suicide Behaviors in Youth

Students who report current POM more likely to report considering attempting suicide, making a suicide plan, attempting suicide

Childhood ADHD May Raise Risk for Later Psychotic Disorder

Findings based on systematic review and meta-analysis of pooled data from 12 studies involving more than 1.85 million participants

High Dose of Vitamin D Does Not Cut COVID-19 Hospital Stay

No significant differences seen for other outcomes among patients hospitalized with moderate-to-severe disease

Text Reminders + Mailed Home Testing Up Colorectal Cancer Screening

Screening rates improved in patients due for testing at a community health center predominantly serving people of color

Sleep Deficiency, Disturbance Tied to Higher Dementia Risk

Older adults followed for five years with poor-quality sleep had higher risk for dementia, earlier death

ASH Issues Guidance for Preventing, Treating VTE in Cancer

Use of thromboprophylaxis not recommended for ambulatory patients at low risk for VTE who are receiving chemotherapy

High Glycemic Index Diet May Up Risk for CV Disease, Death

Diet with a high glycemic index linked to increased risk for major CV event, death for those with, without preexisting cardiovascular disease

Racial, Ethnic Disparities Found in Diagnosis, Treatment of ADHD

Asian, Black, Hispanic children less likely to be diagnosed than Whites; White children more likely to receive some treatment

AstraZeneca COVID-19 Vaccine Easy to Update in Response to Variants

Oxford team working on modifying vaccine to fight new variants, expects new version to be available in the fall

U.S. to Monitor Air Travelers From African Nations With Ebola

As of Feb. 25, Guinea had nine Ebola cases, five deaths; the Democratic Republic of the Congo had eight cases, four deaths

Walmart Expands COVID-19 Vaccination Program

Company will use COVID-19 vaccines supplied by the U.S. Centers for Disease Control and Prevention

J&J COVID-19 Vaccine Granted Emergency Use Authorization

The single-dose Ad26 vaccine is now the third COVID-19 vaccine to be granted an EUA

Axillary Adenopathy Reported After Recent COVID-19 Vaccination

Management approach to these findings includes axillary ultrasound if clinical concern persists six weeks after final dose of vaccine

Decline in U.S. Suicide Rates From 2018 to 2019 Not Uniform

Significant declines seen in five states and certain subgroups, but several states experienced significant increases

Cutaneous Findings Described for Children With MIS-C

Cutaneous findings varied among patients; annular plaques in the proximal medial lower extremities were common

Model Estimates Harm Attributed to Menthol Cigarettes

From 1980 to 2018, menthol cigarettes were responsible for 10.1 million extra smokers, 3 million life years lost, 378,000 premature deaths

Inappropriate Antibiotic Prescribing Common for Women With UTIs

Many women receive prescriptions for inappropriate agents or durations; rural women more likely to receive Rx with inappropriately long duration

Transplant Beneficial for Kidney Failure in Sickle Cell

Patients with kidney failure associated with sickle cell disease are less likely to receive a transplant despite similar reduction in mortality

U.S. Patterns for Recurrent Coronary Heart Disease Examined

Decreases in recurrent MI rates, recurrent CHD event rates, heart failure hospitalization rates, all-cause death greater in women than men

More Frequent Disinfectant Use Tied to Uncontrolled Asthma

Findings seen in a survey of U.S. adults with asthma during the COVID-19 pandemic

Optimal Therapy for Esophageal Cancer Feasible in Fit Elderly

Those 70 years and older have similar postoperative complication scores and long-term survival

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Exposure to Greenspace Linked to Lower Risk for Pediatric-Onset IBD

Risk reduced for both ulcerative colitis, Crohn disease; linear dose response seen across increasing quartiles of greenspace

Markers of Puberty Differ in Girls With More Body Fat

Girls with higher total body fat have delayed breast maturation, as determined by breast ultrasound, and earlier menarche

Many Older Adults Keep and Use Leftover Antibiotics

Authors say further education is needed on appropriate uses of antibiotics

Digital Self-Monitoring Linked to Weight Loss for Adults

Few interventions had digital self-monitoring engagement rates greater than 75 percent of days

Cigarette Smoke Adds to Colorectal Neoplasia Risk in Patients With IBD

Adding smoke exposure improves the current risk stratification for colorectal neoplasia surveillance strategies

Online Portal Guides Users to COVID-19 Vaccination Sites Nationwide

VaccineFinder has been expanded to include more than 20,000 COVID-19 vaccination sites

Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility

Five patients tested positive in outbreaks in July and October 2020; disease severity worse during second outbreak

Model Can Aid Assessment of Multiple Pulmonary Nodules

Validated machine-based learning model performs better than surgeons, radiologists, CADx for predicting malignancy

Treatment to Lower RA Disease Activity Feasible in Pregnancy

In pregnant patients with rheumatoid arthritis, clinicians should strive for remission or low disease activity

Racial/Ethnic Minorities Underrepresented in Vaccine Trials

In adult trials, White patients and women are overrepresented; White patients account for 77.9 percent of participants

Mortality Gap Between Cancer, Heart Disease Narrowing for Women Younger Than 65

Age-adjusted mortality rates decreased for cancer and heart disease from 1999 to 2018, but increased for heart disease from 2010

Early-Onset T1DM Negatively Impacts Brain Development Over Time

Baseline differences in brain volumes and IQ persist or increase over longitudinal follow-up

Decline in Myocardial Function May Start Early in Blacks

Midwall fractional shortening trajectories differ by race from early age to young adulthood

COVID-19 Cases, Deaths Plummet in Nursing Homes After Vaccine Rollout

From late December to early February, new cases among U.S. nursing home residents fell by more than 80 percent

CDC Expands Alert About Listeria Outbreak Linked to Cheese

Three new illnesses linked to the outbreak reported this week

Liver Cancer Profile Differs in Black Patients With Hep C

Black patients have better liver function at the time of hepatocellular carcinoma diagnosis; have less early-stage HCC, larger tumors

U.S. Government to Distribute Millions of Face Masks

Masks will be sent to underserved communities and those hardest hit by the pandemic

Risk Reduced for Positive NAAT Result With SARS-CoV-2 Antibodies

Patients with positive antibody test initially more likely to have positive NAAT result but less likely after 30 days

New Coronavirus Variant Sweeping Through New York City

The new variant is called B.1.526 and was first detected in samples gathered in the city in November

More Than Half of U.S. Adults Use Dietary Supplements

Use higher for women than men; use increased with age, overall and in both men and women

COVID-19 Vaccine Makers Planning for Variants

Pfizer, BioNTech in discussions with regulators about testing an adapted version of their vaccine

Estimated Opioid-Related Costs $14 Billion for Symptomatic Knee OA

Almost half of costs were for lost productivity, criminal justice expenses, cost associated with diversion activities

AAN: Many Patients With Migraine Do Not Get Enough Exercise

Patients with no exercise report increased depression, anxiety, and sleep problems and have more migraines

USPSTF Recommends Low-Dose Aspirin to Prevent Preeclampsia

Substantial net benefit observed for daily low-dose aspirin use in pregnant women at high risk for preeclampsia

Time From eGFR Wait-List Threshold to ESKD Shorter in Blacks

Registering Blacks on transplant wait list at eGFR of 24 to 25 mL/min/1.73 m2 could improve racial equity in wait time prior to ESKD onset

Non-White Race Tied to Higher Likelihood of COVID-19 Infection

Age, not race, most important contributing factor for outcomes

AAN: Smell Loss Can Persist for Five Months After COVID-19

About half of those with compromised sense of smell during acute phase had not regained sense of smell at average of 150.1 days postdiagnosis

Symptoms ID’d That Should Trigger COVID-19 Testing

Testing people with any of seven key symptoms in the first three days of illness would detect 96 percent of symptomatic cases

Nationwide Study Shows BNT162b2 mRNA Vaccine Is Effective

In mass vaccination setting, vaccine is effective for symptomatic COVID-19, hospitalization, severe disease, death

FDA Review Reveals J&J COVID-19 Vaccine Safe, Effective

Advisory panel set to meet Friday to recommend whether the agency should authorize the shot for emergency use

Children Given Flu Shot Less Likely to Have Symptomatic COVID-19

Odds also lower for having severe disease for patients vaccinated for influenza, pneumococcal disease

Polynesian Ancestry May Increase Cardiometabolic Risk

Genetic study reveals link between Polynesian ancestry and higher risk for obesity, T2DM, heart failure in Native Hawaiians

New Coronavirus Variant Surging in California

The B.1.427/B.1.429 variant has been detected in 45 U.S. states to date and in several other countries

Pfizer, Moderna Tell Congress a Big Jump in Vaccine Supply Is Coming

By end of March, Pfizer and Moderna expect to have delivered a total of 220 million vaccine doses to the U.S. government

Pessary Treatment Successful for Symptomatic Pelvic Organ Prolapse

75.3 percent of patients report successful pessary treatment at five-year follow-up, with discontinuation rates decreasing over time

Use of Health Services Up for Adults With Inflammatory Bowel Disease

IBD associated with increased prevalence of being prescribed medication and having received acute care services

Pediatric-Onset Multiple Sclerosis Tied to Lasting Social Consequences

Long-term follow-up shows lower educational attainment, lower income in adulthood

FDA: New Variants Mean COVID-19 Vaccines, Tests May Need Tweaking

Agency offers recommendations for companies seeking to modify already-approved vaccines, medicines, and tests so they can remain effective

Risk for Rheumatoid Arthritis Reduced for Patients With T2DM

Reduced risk may be attributable to statin use; no significant association seen for glycemic control, metformin use on RA risk

Text Message System Useful for Monitoring Postoperative Opioid Use

System deployed in 2,444 patients during 16-month period showed that 61 percent of opioid tablets remained unused

Children Conceived by ART Are Shorter, Lighter at Birth

Children conceived by assisted reproduction technology grow more rapidly after birth; height, weight similar to those naturally conceived by 17

Cocaine Use, HIV Affect Coronary Plaque Morphology

Cocaine use significantly linked to 23.7 percent of radiomic features identified in plaque; HIV infection linked to 1.3 percent

Deceased Organ Donation Rose Among Blacks but Still Lags

Despite gains in deceased organ donation among racial/ethnic groups in the U.S., substantial racial differences remain

Fecal Transplant May Counter Anti-PD-1 Resistance in Melanoma

FMT plus anti-PD-1 therapy may change gut microbiome and help overcome drug resistance in some patients with advanced melanoma

Prevalence of Multiple Chronic Conditions Up Among Veterans

Prevalence of MCC remained higher for male, female veterans after stratification by age and adjustment for sociodemographics

Vascular Deaths Down for Diabetes Patients in the U.K.

Cancer is now the leading contributor to death among individuals with diabetes living in England

FDA Warns Not to Rely on Pulse Oximetry for Diagnosis, Treatment Decisions

Safety communication follows NEJM study showing risk for inaccuracy with use of pulse oximeters in those with dark skin pigmentation

Transplant Recipient Dies After Receiving COVID-19-Infected Lungs

Surgeon who handled the donor lungs also became infected and fell ill but recovered

Trial of Gene Therapy for Sickle Cell Disease Halted

Two patients participating in the study developed cancer years after treatment

COVID-19 Vaccines Adapted to Fight Variants Will Not Require Long Clinical Trials: FDA

Most makers of approved COVID-19 vaccines have said they plan to adapt their vaccines to tackle variants

Amoxicillin-Clavulanate Effective for Outpatients With Diverticulitis

As effective as metronidazole with fluoroquinolone, with reduced risk for one-year Clostridioides difficile infection

Predictors of Death, Discharge ID’d for Diabetes Patients With COVID-19

Younger age, routine metformin therapy, and longer symptom duration on admission positively linked to discharge

Limiting Resident Shifts Cuts Attentional Failures in PICU

After adjustment for workload, rapid cycling work roster schedule has protective effect on rate of serious medical errors

Greater HbA1c Variability May Raise Risk for CVD in T2DM

Severe hypoglycemia may mediate this association

CDC Report Shows No Evidence of Unexpected Adverse Events With COVID-19 Vaccines

Findings from the first month show no unexpected adverse events, with 6,994 adverse events and >90 percent classified as nonserious

SARS-CoV-2, COVID-19 Rates Decreased After One Vaccine Dose

Study among health care workers shows reductions in SARS-CoV-2 infection rates one to 14, 15 to 28 days after first dose of the BNT162b2 COVID-19 vaccine

COVID-19 Vaccine Efficacy Higher With Three-Month Interval Between Doses

For ChAdOx1 nCoV-19 Oxford vaccine, three-month interval results in higher efficacy than six-week interval

Persistent Symptoms Reported for About 30 Percent With COVID-19

At least one persistent symptom reported by 32.7 percent of outpatients with mild illness, 31.3 percent of patients hospitalized

Prevalence Data Suggest Increasing Trend of Psoriasis With Age

Worldwide studies suggest stable or slightly decreasing trend in incidence of psoriasis and increasing trend in prevalence

Testosterone Therapy Does Not Improve Vascular Function

Exercise training, but not testosterone, improves endothelium-dependent vascular function in men with low-normal testosterone

Listeria Outbreak Spurs Recall of Queso Fresco Cheeses

There have been seven illnesses reported so far; all patients were hospitalized

GERD Linked to Squamous Cell Cancers of Larynx, Esophagus

An estimated 16.92 and 17.32 percent, respectively, of cases of LSCC and ESCC among individuals aged 50 to 71 years linked to GERD

All British Adults Should Have First COVID-19 Shot by July 31: Government

Announcement made as government prepares a 'cautious' reopening plan

Proinflammatory, Low-Quality Maternal Diet Linked to Adiposity

Odds of late childhood overweight and obesity increased with more proinflammatory diet in early pregnancy

Bone Cancer Survivor Selected for SpaceX Flight

Hayley Arceneaux will join billionaire Jared Isaacman, who wants to raise $200 million for St. Jude Children's Research Hospital

U.S. COVID-19 Hospitalizations at Lowest Level Since November

There were about 59,800 COVID-19 patients in hospitals nationwide on Friday, a 55 percent decrease from Jan. 6

Aspirin Overused, Statins Underused for CVD Prevention in Seniors

56.4 percent aged 75 years and older using statin for secondary cardiovascular event prevention; 45.3 percent taking aspirin for primary prevention

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Mortality Highest for Asians, Hispanic/Latinos With Lupus

Among patients with systemic lupus erythematosus, mortality is increased for minorities, especially Asian, Hispanic/Latina women

Pediatric Inpatient Admissions Down During Pandemic

Findings seen across a wide range of diagnoses and not reflective of seasonal variation

Socioeconomic Status Tied to Multisystem Inflammatory Syndrome in Children

Low socioeconomic status, high social vulnerability index, racial/ethnic minority linked to MIS-C

Factors Associated With Fracture Risk in Middle Age ID’d

Factors independently linked to incident fracture include age, sex, BMI, level of leisure-time physical activity

Among Blacks, Late-Stage HIV Diagnosis Varies by Rurality

Across rural, urban, metropolitan areas, linkage to care within one month of diagnosis was similar but below targets

U.S. to Provide $4 Billion for International COVID-19 Vaccine Program

U.N. Secretary-General Antonio Guterres says that 130 countries have not received a single dose of the vaccine

Lenvatinib Plus Pembrolizumab Tops Sunitinib in Advanced RCC

Progression-free, overall survival significantly longer with combo versus sunitinib for advanced renal cell carcinoma

Pfizer to Begin Clinical Trial of COVID-19 Vaccine in Pregnant Women

Pfizer also planning to start trials of the vaccine in younger children, teens, people with weakened immune systems

Age-Adjusted Suicide Rates Decreased From 2018 to 2019 in U.S.

2019 rates significantly lower in women aged 25 to 44 years and in boys and men aged 10 to 14, 45 to 64, and 65 to 74 years

Water Problems Plague Texas Hospitals After Storm

Hospitals experiencing water pressure issues as well as widespread power outages

Discharge to Survival After Out-of-Hospital Cardiac Arrest Lower for Women

Among patients who were not made DNR and did not have withdrawal of life-sustaining therapy, women had lower discharge survival

T2DM in Middle Age Ups Mortality Risk in COVID-19 Infection

Excess COVID-19 death risk from type 2 diabetes decreases with increasing age

COVID-19 Death Count Varies With Race of Nursing Home Residents

Nursing homes with lowest versus highest proportion of White residents have higher COVID-19 death counts

Scoring Tool Predicts Seven-Day Stroke Risk After TIA

Risk prediction using Canadian TIA Score accurate with or without carotid endarterectomy/carotid artery stenting

Genetic Mutations May Add to Racial Disparity in Child B-ALL

Increased incidence of IKZF1 deletion and IGH-CRLF2 translocation seen in Hispanic/Latino children with B-ALL

Age, Frailty Independently Linked to COVID-19 Mortality

Frailty also associated with increased risk for higher care needs on discharge and increased likelihood of adverse outcomes

Many U.S. Troops Refusing COVID-19 Vaccination

Up to two-thirds of troops who were offered the vaccine have accepted, according to 'very early data'

Dementia Risk Up in Men With Genetic Mutation for Hemochromatosis

Male p.C282Y homozygotes have lower T2* measures on brain MRI in areas including the putamen, thalamus, hippocampus

Millions of Counterfeit N95 Masks Seized

Medical workers and companies should go to the 3M website to learn how to identify fake masks

Certain Prostate Drugs Tied to Risk for Parkinson Disease

Use of glycolysis-enhancing drugs terazosin, doxazosin, or alfuzosin tied to lower risk for developing Parkinson disease than use of tamsulosin

FDA Approves Therapy to Protect Bone Marrow Cells From Effects of Chemotherapy

Cosela reduces the frequency of bone marrow suppression caused by chemotherapy for extensive-stage small cell lung cancer

Decrease Seen in U.S. Life Expectancy in First Half of 2020

Life expectancy decreased by 1.0 year in first half of 2020 from 2019, with decreases of 1.2 and 0.9 years for males and females, respectively

Myocardial Injury Prevalent in Patients With Severe COVID-19

54 percent of discharged patients who had troponin elevation in conjunction with severe COVID-19 had late gadolinium enhancement and/or ischemia

Relugolix Combo Therapy Beneficial for Fibroid-Related Menorrhagia

Significantly more women had reduced menstrual bleeding with once-daily relugolix combination therapy versus placebo

Avacopan Noninferior to Prednisone for ANCA-Associated Vasculitis

Avacopan noninferior to prednisone taper for remission at week 26, superior to prednisone taper for sustained remission at week 52

1998 to 2018 Saw Jump in Admissions for Food-Induced Anaphylaxis

U.K. data revealed decrease in case fatality rate during study period; cow's milk responsible for 26 percent of deaths in school-aged children

Biomarker May Predict Treatment Outcome in Advanced Melanoma

Changes in plasma levels of ctDNA associated with survival outcomes in BRAF V600 mutation-positive unresectable or metastatic melanoma

White Matter Hyperintensities Characterized in Dementia

Association seen for larger volumes of white matter hyperintensities with disease severity, but not vascular risk, in bvFTD

Enfortumab Vedotin Prolongs Survival in Advanced Urothelial Cancer

Overall survival longer compared with standard chemo for disease progression following platinum-based chemo and PD-1 or PD-L1 inhibitor

Mortality Lower for Veterans Receiving Posttransplant Care in VA

Mortality significantly higher for patients receiving care after kidney transplant in Medicare only, dual care

Zinc, Ascorbic Acid Do Not Cut Symptom Duration in SARS-CoV-2

No difference in length of time required to achieve 50 percent reduction in symptoms seen with supplements versus usual care

Methylprednisolone Added to IVIG May Cut Fever in MIS-C

IV immunoglobulins plus methylprednisolone associated with lower risk for treatment failure compared with immunoglobulins alone

Cabozantinib Prolongs PFS in Papillary Renal Cell Carcinoma

Progression-free survival longer and response rate greater for cabozantinib versus sunitinib in phase 2 trial in adults with PRCC

CPR Quality Impacts Survival in In-Hospital Cardiac Arrest

Number of pauses greater than 10 seconds during resuscitation linked to survival for four end points

Primary PCI Use Down for Cancer Patients With STEMI

Rates of associated in-hospital all-cause mortality, major adverse cardiovascular and cerebrovascular events lower for cancer patients

CRISPR-Based Testing Feasible for SARS-CoV-2 Screening

Study finds technology shows concordance with PCR testing and can detect leading edge of outbreak in asymptomatic people

Canadian Study Confirms COVID-19 More Serious Than Influenza

Relative risks increased for in-hospital mortality, ICU use, hospital length-of-stay during first wave of pandemic