Dialectical Behavior Therapy Tied to Fewer Suicide Attempts
Findings seen for the high-risk population of teens with bipolar spectrum disorder
High-Intensity Statins Underused With Atherosclerotic Cardiovascular Disease
Authors say findings show gaps between practice and guideline-based care
Subsequent Breast Cancer Risk Higher for Child Cancer Survivors Receiving Doxorubicin
More than twofold increase in risk seen for those treated with ≥200 mg/m² cumulative doxorubicin versus no doxorubicin
Cediranib Shows Promise for Differentiated Thyroid Cancer
No significant improvement in progression-free, overall survival seen with addition of lenalidomide to cediranib
Respiratory Infections in Childhood Increased With Urbanized Living at Birth
Environmental factors, including breastfeeding and visible damp, are associated with risk for infections
USPSTF Recommends Screening for Hypertensive Disorders of Pregnancy
Screening with blood pressure measurements has substantial net benefits and is recommended throughout pregnancy
Four Genetic Variants ID’d for Risk for Progressive Multifocal Leukoencephalopathy
All four risk variants were predicted to be deleterious and were located in two immune pathways
Pneumococcal Infection Reduced in Children With Sickle Cell Since PCV13
After 2010, all invasive pneumococcal infection serotypes were those not included in 13-valent pneumococcal conjugate vaccine
Extended-Release Buprenorphine Not Necessarily Cost-Effective
Extended-release buprenorphine not cost-effective when transmucosal buprenorphine is available for treatment of OUD
Premenopausal Bilateral Oophorectomy Linked to Chronic Conditions
More chronic conditions seen in late midlife for women with history of PBO with or without hysterectomy
Sputum Purulence Can Predict Outcomes in Bronchiectasis
Patients with more purulent sputum experience more exacerbations and more severe exacerbations
Cases of Pediatric Therapeutic Errors Related to ADHD Meds on the Rise
Likelihood of experiencing a serious medical outcome or being admitted to a health care facility was increased for children younger than 6 years
AAP Issues Low-Carb Diet Recommendations for Pediatric Diabetes
Safety concerns to consider for youth with diabetes who are restricting carbohydrates include growth deceleration, poor bone health
Ventilatory Burden Can Assess Severity of Obstructive Sleep Apnea
Ventilatory burden can also predict all-cause and cardiovascular disease mortality
Revaccination Suggested for Hep B Vaccine Nonresponders After Hep C Cure
Revaccination should be considered for patients with chronic HCV who do not respond to HBV vaccination
Use of AI Plus One Radiologist Noninferior for Detecting Breast Cancer
Double reading by one radiologist plus AI noninferior to standard-of-care double reading by two radiologists
Risk for Intracerebral Hemorrhage May Be Transmissible Via Blood Transfusion
Risk was increased for those receiving transfusion from donors who later developed multiple spontaneous intracerebral hemorrhages
Advanced Young-Onset Adenoma Increases Colorectal Cancer Risk
However, overall 10-year colorectal cancer incidence relatively low in veterans younger than 50 years of age
AI Tool May Aid Remote Assessment of Parkinson Symptom Severity
Performance better than certified rater but not quite as good as expert neurologists
Both Maternal, Paternal Substance Use Disorder Tied to Offspring Intellectual Disability
Authors say preventive efforts should focus on fathers, too
Air Pollution Exposure Tied to Smaller Babies at Birth
However, living in a greener area could help counteract this effect
Economic Burden of Youth Violence Reached $122 Billion in 2020
Total annual economic burden of youth violence 17 percent higher in 2020 due to increase in youth homicides
Infection With Omicron Less Likely to Result in Post-COVID-19 Condition
No variation in risk for PCC seen based on number of vaccinations, but previous infection linked to reduced PCC risk
Parent-Support Early Childhood Obesity Intervention Beneficial
No between-group difference seen in BMI-standard deviation score, but significant difference seen in reduction of BMI-SDS ≥0.5
Memories Reported by Some Patients Undergoing CPR for Cardiac Arrest
Normal EEG activity consistent with consciousness emerged as long as 35 to 60 minutes into CPR despite marked cerebral ischemia
Head Injury Linked to Increase in Incident Ischemic Stroke
Dose-response association seen for risk for stroke with number of head injuries, but no association seen for severity
Physical Therapy Linked to Drop in Falls for Patients With Dizziness
Receipt of physical therapy within three months of presentation linked to reduced risk for subsequent falls
Tobacco, Cannabis Use Tied to High Rates of Self-Reported Mental Health Issues
Daily use of cigarettes, e-cigarettes, and cannabis associated with both anxiety and depression
Reproductive Factors Linked to Risk for Lung Cancer
Early menarche, early menopause, shortened reproductive life span linked to increased risk, especially for NSCLC
Lorundrostat Effective for Lowering BP in Uncontrolled Hypertension
Changes in office systolic BP of −14.1, −13.2, −6.9, and −4.1 mm Hg seen with 100, 50, 12.5 mg once daily of lorundrostat and placebo
Use of Nonselective β-Blockers Tied to Lower Risk for Total Knee Arthroplasty
Any β-blocker use cuts odds by nearly half, driven by nonselective β1-blockers
Concurrent Use of Fentanyl, Stimulants Common in Overdoses
Proportion of stimulant involvement in fentanyl-involved overdose deaths increased in almost every state from 2015 to 2021
E-Cigarettes, Cytisine, Varenicline Most Effective to Help Stop Smoking
Combination of a patch and fast-acting nicotine replacement therapy also effective
Rates of Sexual Dysfunction High in Patients With Schizophrenia
Review showed that treating depression was associated with lower rates of sexual disorders
HRQoL Consistently High for Out-of-Hospital Cardiac Arrest Survivors
Long-term health-related quality of life consistently high up to 20 years after the event
Diet, Exercise Intervention May Aid Chemotherapy Outcomes in Breast Cancer
Although relative dose intensity similar, pathologic complete response higher with intervention
Choking Hazard Spurs Recall of Bath Toys Sold at Target
Consumers should immediately stop using the recalled water bead kits and take them away from children
BNT162b2 Vaccination Linked to Lower Risk for COVID-19 Encounters in Children Under 5
Vaccination linked to reduced odds ratio of COVID-19-related emergency department or urgent care encounter, outpatient visits
Intensity-Modulated Radiation Therapy Best for Locally Advanced NSCLC
Intensity-modulated radiation therapy spares more normal tissue than 3D-conformal radiotherapy
Treatment of Lower Urinary Tract Symptoms Tied to Reduced Risk for Death in Men
Significant reductions seen in death with 1-point improvement in AUA Symptom Score, and in storage and voiding subscales
Home-Based Ovulation Monitoring Feasible for Timing Frozen-Thawed Embryo Transfer
No difference seen in ongoing pregnancy versus hospital-controlled ovulation monitoring
Minimally Processed Red Meat Can Work in Weight Loss Diet With Diabetes
High-protein, lean beef diet achieved similar weight loss, glucose control as normal-protein diet with no red meat
Interventions Can Increase Adjuvant Endocrine Treatment Adherence
Findings based on meta-analysis involving more than 360,000 breast cancer survivors
Immune Response Not Inferior With Coadministration of COVID-19, Flu Shots
Similar immune response and no increase in rate of reactogenicity events seen with coadministration versus COVID-19 vaccine alone
Factors Identified for Readmission Among Children With ARDS
Respiratory and nonrespiratory complex chronic conditions, tracheostomy placement, LOS ≥14 days linked to readmission; one-year readmission probability was 30 percent
Improvement Seen in Reproductive Hormone Levels With Keto Diet in PCOS
LH/FSH ratio and serum free testosterone reduced, while serum sex hormone-binding globulin increased with ≥45 days of diet
Exercise Stress Tests Can Also Predict Noncardiovascular Deaths
Low functional aerobic capacity, abnormal heart rate recovery, and low chronotropic index tied to noncardiovascular death
Hypertension, Statin Use Increased for Individuals Using TAF for PrEP
Incident hypertension, statin use higher with tenofovir alafenamide fumarate compared with tenofovir disoproxil fumarate
Increasing Proportion of Visits Delivered by Nurse Practitioners, PAs
Proportion of visits delivered by nonphysicians varies across conditions, from 13.2 percent for eye disorders to 41.5 percent for respiratory infections
Parent Drinking Behaviors Linked to Adolescent Drinking
Teens whose parents drink frequently or binge drink have significantly higher odds of drinking
Seniors With Digestive Disease More Likely to Have Loneliness, Depression
Loneliness, moderate-to-severe depression associated with greater odds of poor-to-fair health
Beauty Salon-Based Intervention Builds Knowledge of PrEP in Black Women
One challenge is that women perceive their risk for HIV infection as low
Online Peer-Delivered Cognitive-Behavioral Therapy Aids Postpartum Depression
Other benefits seen for improved maternal social support, infant-focused anxiety, and negative emotionality in infants
Racial Disparities Seen in Presentation of Frontotemporal Dementia
Black individuals exhibit higher frequency of delusions; Asian individuals have higher frequency of apathy
Prescribed Medical Cannabis Use Tied to Better Health-Related Quality of Life
Findings seen in real-world patients with a range of chronic health conditions
Methylation Score Can ID Risk for Cervical Adenocarcinomas
Methylation score had sensitivity of 74 percent, specificity of 89 percent for adenocarcinoma in situ/adenocarcinoma
Seasonal Difference Observed in Systolic Blood Pressure
Seasonal variation of 1.4 mm Hg tied to nearly 5 percent variation in blood pressure control
Hypertension While Lying Down Tied to Worse Cardiovascular Disease Outcomes
Findings seen regardless of whether hypertension persists in seated position
Testosterone Therapy Tied to Better Mental Health
Findings seen for transgender and gender-diverse individuals desiring testosterone therapy
Cardiac Arrest Survival Lower at EMS Agencies Serving Minority Populations
Difference not explained by response times, rates of EMS termination of resuscitation, or rates of initiating CPR or automated external defibrillator
Hypoattenuation Thickening on CT Prognostic After Left Atrial Appendage Occlusion
High-grade hypoattenuation thickening on follow-up CT after left atrial appendage occlusion associated with higher stroke risk
CDC Panel Gives Support to New COVID-19 Booster Shots
New booster targets the XBB.1.5 omicron subvariant, which is similar to the dominant variant now circulating
Risk for Dementia Reduced in Association With Antihypertensive Use
Individual patient data meta-analysis shows increased risk for dementia for those with untreated hypertension
Receipt of PT, Chiropractic Care Reportedly Low for Comorbid Chronic LBP, Opioid Use Disorder
Receipt of physical therapy and chiropractic care was low overall and lower across racial, ethnic minorities
AACR Cancer Progress Report Reveals 33 Percent Decrease in Cancer Death Rate, 1990 to...
Report highlights advances such as approval of 14 new anticancer therapeutics, expansion of use of 12 previously approved therapeutics
17 Percent of Patients Seeing Neurologist Travel Long Distance
Factors associated with long-distance travel include low neurologist density, rural setting, and visits for ALS, nervous system cancer
Cyberbullying Tied to Eating Disorder Symptoms in Early Adolescence
Authors say screening may be recommended
A Year After Launch, OTC Hearing Aids Are Not Catching on With U.S. Consumers
A year after the U.S. Food and Drug Administration approved the devices, only a small fraction of people with hearing difficulties have bought one
California Legislature First to Pass Ban on Four Food Additives Linked to Health Issues
The chemicals are already illegal in the European Union and other places around the world
Whites Have Greatest Magnitude of Association of Socioeconomic Status With LE8
Magnitude of positive association for four socioeconomic status categories with LE8 was greater for non-Hispanic Whites than minority groups
Adults Overdue for CRC Screen Rarely Receive Recommendation for Screening
Prevalence of reporting clinician recommendation was lower for non-Hispanic Asian, Black, Hispanic versus White adults
Lead Exposure Poses Considerable Global Health, Economic Burden
>90 percent of total global IQ loss and cardiovascular disease deaths occurred in low-, middle-income countries
Shorter Leucocyte Telomere Length Linked to Dementia Risk
Shorter leucocyte telomere length also associated with smaller total brain volume, white matter volume, hippocampus volume
Time Spent in Sedentary Behavior Tied to Incident Dementia in Seniors
Significant, nonlinear association identified between time spent in sedentary behavior and incident dementia
Coronary CTA-Derived Fractional Flow Reserve Can ID Three-Year Outcomes in Angina
Risk for all-cause death, nonfatal spontaneous myocardial infarction identified in overall cohort, those with high coronary artery calcium scores
Fine Particular Matter Linked to Increase in Breast Cancer Risk
Significant increase in risk seen for ER-positive breast cancer, but not ER-negative tumors
Half of Older Adults With Glaucoma Unaware They Have It
Furthermore, two-thirds with undiagnosed glaucoma had normal intraocular pressure
FDA Panel Says Common OTC Decongestant Is Useless
Panel's recommendation could prompt the FDA to pull all oral decongestants containing phenylephrine from store shelves
Curcumin, Omeprazole Similarly Effective for Functional Dyspepsia
Significant improvements seen in symptoms on days 28 and 56; no synergistic effect seen for combination treatment
Children With Down Syndrome Experience More Medical Imaging
More medical imaging, including CT, fluoroscopy, angiography, nuclear medicine, reported for those with Down syndrome, especially in those younger than 1 year
Few With CRC in Sub-Saharan Africa Receive Guideline-Concordant Care
Risk for death 3.49 times higher for those receiving no cancer treatment versus standard treatment or treatment with minor deviations
Antipsychotic Use Increased for Seniors With Alzheimer, Related Dementias
Among patients with ADRD receiving care from a home health agency, antipsychotic use was tied to less improvement in activities of daily living
ChatGPT Accurately Handles Questions About Vaccine Hesitancy
Findings seen for 50 most common questions about false information, myths, and false and true contraindications
ED Pediatric Readiness Cuts In-Hospital Mortality
However, pediatric readiness does not eliminate Black mortality disparity for children's medical emergencies
Objective Measures of Social Visual Engagement Aid Early Diagnosis of Autism
Test able to quantify diagnostic status as well as individual levels of social disability, verbal ability, and nonverbal ability
Evening Chronotype Linked to Increased Risk for Type 2 Diabetes
Positive association seen after accounting for all measured lifestyle and sociodemographic factors
Flu Vaccine Cut Risk for Influenza-Linked Hospitalizations in 2023
Interim data show vaccine effectiveness of 51.9 percent in five South American countries during their flu season
FDA Approves New COVID-19 Booster Shots
New booster targets the XBB.1.5 omicron subvariant, which is similar to the dominant variant now circulating
Red Cross Appeals for Donors During National Blood Shortage
Back-to-back climate-related disasters have hampered blood collection efforts, and a summer shortfall has made the shortage worse
Americans Who Are Deaf Can Now Use 988 Suicide Helpline
The services use a videophone device that transmits video and audio
Gefapixant Leads to Modest Improvements in Cough
Modest improvement seen in cough frequency, severity, and specific quality of life, but increase seen in treatment-, taste-related adverse events
Risk for Death, Cardiovascular Death Lower for OSA Patients Using CPAP
Reduction seen in low-density coronary artery plaque volume with CPAP and with use of CPAP and GLP-1-mediated weight loss
Increase Seen in COPD Hospital Admissions Since 2010 in Canada
Age-standardized rates increased among younger women and men and older women, while they declined in older men
Opioids Can Be Continued in Cancer Patients With Nonmedical Stimulant Use
Regardless of prognosis, panel deemed it appropriate to continue opioids, increase monitoring, and avoid opioid tapering
Heat Exposure During Pregnancy Linked to Severe Maternal Morbidity
Greater associations seen for mothers with lower educational attainment, those whose pregnancies started in cold season
Severity Reduced With Mpox Reinfection, Postvaccination Infection
Shorter disease course with less mucosal disease seen on reinfection versus initial infection
Link Explored for NSAID Use, Hormonal Contraception, VTE Risk
NSAID use positively linked to VTE, with extra VTE events in those with concomitant high-, medium-risk contraception use
Growing Pains May Be Precursor to Migraine
Significantly more children and adolescents with growing pains had headaches fulfilling criteria of migraine without aura, probable migraine
Being in Good Shape Tied to Fewer Mental Health Rx
Reduction in need for anxiolytic drugs, antidepressants strongest for men and young and middle-aged adults
Redo Transcatheter Aortic Valve Replacement Safe, Effective
Death and stroke rates similar to those in patients with a similar clinical profile and predicted risk undergoing TAVR for native aortic valve stenosis
Company Pulls ‘One Chip Challenge’ From Store Shelves After Teen Dies
Hospitalizations from the One Chip Challenge have been reported across the country
Patients May Not Have Choice in Behavioral Health Visit Modality
Nearly half of patients report they do not believe their clinician considered their modality preferences when deciding on in-person versus virtual visit
Pulmonary Embolism-Related Mortality Remained Unchanged From 2006 to 2019
Age-adjusted mortality rate increased for men versus women and Black versus White patients
Black-White Disparities in Cognition Declined Between 2008 and 2017
However, disparities persisted among seniors in functional limitations and limitations in activities of daily living
Depression, Inflammation Linked in Obese Patients Undergoing Bariatric Surgery
Higher baseline hsCRP predicts poorer weight loss but has no effect on depression severity
Alzheimer, Parkinson Disease Share Protective Association at HLA Locus
Protective HLA-DRB1*04 subtypes bind strongly to aggregation-prone tau PHF6 sequence when acetylated at K311
Hypertension, Anemia Contribute to Racial Disparities in Severe Maternal Morbidity
Population attributable risk percentage for antepartum anemia and SMM highest for multiracial, Black, Hispanic patients
Food Additive Emulsifier Intake Linked to Risk for CVD
Higher intake of celluloses (E460 to E468) positively associated with higher risks for CVD and coronary heart disease
Upfront Combo Lipid-Lowering Therapy Best for Acute Coronary Syndrome
Combination approach better than statin monotherapy for all-cause mortality at one, three, and five years in acute coronary syndromes
Small Changes in Bone Mineral Density Can Reduce Hip Fracture Risk
Small improvements in femoral neck BMD coincided with significant reduction in incidence of hip fracture in men and women
Linguistic Disparities Impact Patient Access to Cancer Care
Non-English-speaking patient callers to hospital are less likely to be provided with next steps to access cancer care
Providers Have Inadequate Awareness of PCV20 Vaccination Recommendations
Two-thirds of health care providers agree with expanding recommendations for new PCV20
Racial, Ethnic Disparities Seen in Type 2 Diabetes After GDM
Associations between education, Medicaid, WIC participation, body mass index with T2DM were more pronounced among White individuals
Adverse Association Identified for Calcium Channel Blocker Use, Glaucoma
CCB use also linked to thinner macular ganglion cell-inner plexiform layer, macular retinal nerve fiber layer thickness
Company Reaches $479 Million Settlement Over Defects in CPAP Machines
The machines were recalled in June 2021 by the U.S. Food and Drug Administration
Hepatitis C Virus Still Leading Cause of Hepatocellular Cancer in Men
Since 2017, leading cause of HCC is NAFLD among women; increases in ALD- and NAFLD-HCC seen since 2015
FDA Approval of New COVID-19 Boosters Could Come by Friday
The new booster targets the XBB.1.5 omicron subvariant, which is similar to the dominant variant now circulating
Early-Onset Cancer Morbidity Continuing to Increase
Main risk factors underlying early-onset cancers are dietary risk factors, alcohol consumption, and tobacco use
Opioid-Free Discharge Feasible After Pancreatectomy
In a recent study, there was an increase in the percentage of patients discharged opioid-free
Eye Tracking of Social Visual Engagement Predicts Autism Diagnosis
Findings seen among 16- to 30-month-old children referred to specialty autism clinics
In Situ, Invasive Melanoma Diagnoses Decreased in 2020
Significant decrease seen in incidence of stage I melanomas but not other stages
Cannabis Legalization, Commercialization Linked to Traffic Injuries
Threefold increase reported in quarterly rate of cannabis-involved traffic injury ED visits during commercialization
ADHD Is Independent Risk Factor for Psychiatric Disorders
Independent association seen for genetic liability to ADHD with risk for anorexia nervosa; bidirectional link noted to major depressive disorder
No Change Seen in Frequency of Recurrent Vertigo Attacks Over Time
Attack frequency did not change over three years for people with benign recurrent vertigo, Meniere disease, or vestibular migraine
Early Clean Intermittent Catheterization Recommended With Neurogenic Bladder
High-grade vesicoureteral reflux is crucial risk factor for recurrent febrile urinary tract infections in children
Statin Use Linked to Reduced Risk for CRC Incidence, Mortality in Patients With IBD
Benefit for incident CRC was duration-dependent, with significantly reduced risk after two or more years of use
DOACs Reduce Dementia Risk Versus Warfarin in A-Fib
Significant reductions were seen in dementia risk for rivaroxaban, apixaban, and dabigatran versus warfarin in network meta-analysis
Traumatic Brain Injury Linked to Cognitive Decline in Twin Study
History of TBI, TBI with loss of consciousness, older-age TBI linked to lower cognitive scores at age 70 years
Atezolizumab Can Induce Response in Alveolar Soft Part Sarcoma
Anti-PD-L1 agent induces sustained responses seen in about one-third of patients with advanced alveolar soft part sarcoma
Panel of 48 CSF Proteins Complements Existing Alzheimer Biomarkers
CSF 48 panel plus existing biomarkers significantly improved diagnostic performance for outcomes studied
Revisional-RYGB Examined for GERD and Weight-Loss Failure
Almost all patients had remission of reflux symptoms after R-RYGB following sleeve gastrectomy
Urinary Biomarkers Can Differentiate IC/BPS From Other LUTDs
Urinary TNF-α and eotaxin levels can differentiate interstitial cystitis/bladder pain syndrome from other dysfunctions in men
Clinical Severity Staging System May Aid Tx Selection for Meniere Disease
Decreased vertigo severity, comorbidity burden, and absence of hearing loss tied to conservative treatment response
Decrease in U.S. Preterm Mortality Seen in Recent Decades
Relative risk for preterm mortality widened over time for nonsmokers, those with high levels of education
Availability of CVD Meds Varies by Low-Cost Generic Program
Variation in coverage seen by program, drug, and cardiovascular disease condition
CDC Warns of Rise in RSV Cases Among Young Children, Infants
Spike in severe cases seen in Florida and Georgia; regional increases usually predict the beginning of RSV season, according to CDC
CDC: Warm Waters Raise Risk for Flesh-Eating Bacteria
Infections have been mostly seen in Gulf Coast states; infections in the Eastern United States have increased eightfold from 1988 to 2018
Moderna Says Updated COVID-19 Vaccine Shields Against Highly Mutated New Variant
Scientists found the variant appears to be less concerning than initially thought, with data showing it is 60 percent less infectious than XBB.1.5 variants
Obesity-Linked CV Mortality Increased From 1999 to 2020
Highest age-adjusted mortality rates seen for Black individuals, and greatest temporal increase found in American Indian and Alaska Native individuals
Overdose Deaths Involving Counterfeit Pills Increasing in U.S.
Quarterly percentage of deaths more than doubled with evidence of counterfeit pill use from July to September 2019 to October to December 2021
Fewer Complications Seen With Vitamin C, D Supplementation in AML
Overall survival did not differ, but significant interaction found between supplementation and NPM1 with survival
Diagnostic Performance of AI Comparable to Humans for Mammograms
Diagnostic performance comparable for two test sets from the Personal Performance in Mammographic Screening scheme
OOP Costs Often Exceed Discount Card Pricing for Select Generics
OOP payments exceeded Amazon and GoodRx prices for 40 and 79 percent of prescriptions assumed to be in deductible phase
In-Hospital Adverse Events Similar for Haloperidol, Atypical Antipsychotics
Comparable rates of in-hospital adverse events seen among seniors prescribed oral antipsychotics after major surgery
Major Discharge Barriers Present for One in 10 Hospitalized Patients
Prolonged length of stay is often due to need for skilled therapy or daily living support in medically ready patients
Infertility Tx Tied to Higher Risk for Stroke Hospitalization
Risk for stroke hospitalization within 12 months of delivery higher for those who received infertility treatment versus spontaneous conception
Sleep Apnea Treatment Cuts Nighttime Heartburn, Respiratory Symptoms
Positive airway pressure treatment itself associated with less wheezing
Chronic Traumatic Encephalopathy Seen in Young, Deceased Athletes
However, clinical correlates of pathologic brain conditions are still uncertain
Cannabis May Be Tied to Increased Risk for Psychiatric Outcomes
However, cannabis and cannabis-based medicines may aid certain clinical conditions
Apixaban Has Lower Bleeding Risk for Initial Anticoagulation for Venous Thromboembolism
During extended treatment, bleeding risk was similar for apixaban and rivaroxaban
Smoking Increases Risk for Mental Illness
Smoking increased the risk for being hospitalized with a mental illness by 250 percent
More Than One in Four Older Adults Report Falling in the Previous Year
Self-reported falls more common in women, but fall-related deaths more common in men
Half as Many Internal Medicine Residents Pursuing General Internal Medicine
Simultaneously from 2009-2011 to 2019-2021, interest in hospital medicine gained popularity
Most of the Effect of Paroxetine for Treating Hot Flashes May Be Placebo Effect
Authors say mean treatment effect for hot flash frequency may only be 21 percent
EASD: Low-Dose Aspirin Tied to Lower Risk for New Diabetes in Older Adults
Findings show low-dose aspirin also slows the increase in fasting plasma glucose over time among initially healthy older adults
Overactive Bladder Symptoms Common With Pelvic Organ Prolapse
Just over one-third of women experienced improvement in symptoms across treatment modalities
Alterations in Infant Gut Microbiota Precede Development of Eczema
Similar patterns also observed in C-section-born infants
Mitotane Not Needed With Low- to Intermediate-Risk Adrenocortical Carcinoma
No significant improvement seen for relapse, but treatment was associated with side effects
Psilocybin Tied to Fewer Symptoms With Major Depressive Disorder
Significant benefit seen as early as eight days compared with placebo
Young Smokers Report More Ocular Symptoms
Teen, young adult users of e-cigarettes and cigarettes more likely to have severe, frequent ocular symptoms
Higher Administrative Payment Burden Causes Delays in Cancer Care
Younger patients, African American patients appear to have more cost-related delays/nonadherence
Erectile Dysfunction May Be Marker for Prediabetes, Diabetes
Authors urge glycemia screening in younger men presenting with ED
Marijuana Users Have Higher Metal Levels in Blood, Urine
Cadmium and lead levels significantly higher among exclusive marijuana users
Gut Microbiome May Predict Later Peanut Allergies
Infants who eventually developed peanut allergies had lower gut microbiome diversity during their early years
Federal Government to Regulate Staffing at Nursing Homes for First Time
Proposal would set minimum staffing to equivalent of three hours per resident per day, with just over a half hour of that time from a registered nurse
Factors ID’d That Increase Risk for Mechanical Ventilation With Sepsis
However, risk factors change depending on time from diagnosis and comorbidities
Psychosocial Stressors Tied to Incident Atrial Fibrillation in Postmenopausal Women
Analysis revealed two clusters of highly correlated psychosocial factors -- stress and strain
Female Surgeons Have Lower Rates of Adverse Postoperative Outcomes
Findings persist for common surgeries when accounting for patient, procedure, surgeon, and other characteristics
Concizumab May Be Effective Prophylaxis for Hemophilia A or B With Inhibitors
Overall median annualized bleeding rate was 0 with concizumab
Drinking Water Quality Tied to Lung Infections in Patients With Cystic Fibrosis
High levels of sulfate, vanadium, molybdenum in water supplies may increase the risk for nontuberculous mycobacteria pulmonary infections
Even Five Years Postapproval, Many Drug Studies Remain Nonpublic
Authors urge greater transparency of study results for drugs approved by the FDA
Rates of Tx Retention for Rifaximin Low Despite Benefits for Hepatic Encephalopathy
Lower treatment retention rates seen with 30-day, out-of-pocket costs ≥$150
Warning Symptoms May Predict Sudden Cardiac Arrest
Warning symptoms differed significantly between patients with sudden cardiac arrest and controls, but were sex-specific
Zolbetuximab Plus CAPOX Beneficial for Advanced mG/GEJ Adenocarcinoma
Progression-free survival and overall survival prolonged with zolbetuximab plus CAPOX versus placebo plus CAPOX
Patient Experience Scores for Hospital Care Decreased During COVID-19
Higher-performing and higher-staffed hospitals prepandemic were slower to decline, but all declined by Q4 of 2021
Prostate-Specific Antigen Levels Posttreatment May Not Predict Overall Survival
Biochemical recurrence does not meet the criteria to be a reliable surrogate endpoint for overall survival
Delays in Endometriosis Diagnosis Tied to Increased Health Care Utilization
Increased health care utilization seen up to 10 years before diagnosis with increases closer to diagnosis
Atopic Dermatitis Increases Risk for Inflammatory Bowel Disease
Risk varies by age, atopic dermatitis severity, and inflammatory bowel disease subtype
Tech ‘Glitch’ Causing Children to Lose Medicaid Coverage
Automated systems involved in large-scale eligibility review are causing entire households to be removed from Medicaid coverage, but children may still be eligible
Marijuana Should Be Moved to Lower-Risk Drug Category, U.S. Health Officials Say
The move would not legalize marijuana, but could move it from its Schedule I classification to a Schedule III
Tx of Postnatal Depression Tied to Better Maternal, Offspring Outcomes
Selective serotonin reuptake inhibitor treatment tied to lower risk for maternal mental health problems and child externalizing behaviors across early childhood
Omega-3, -6 Fatty Acids No Aid for Vision Among Extremely Preterm Infants
Findings seen for visual acuity at 2.5 years of corrected age, but authors note that high loss to follow-up rate may have impacted findings
Subcutaneous Securement System Best for Reaching End of PICC Need
Subcutaneous anchor securement system better than adhesive securement device for reaching end of need with a single PICC
Mortality Lower for Patients With Obesity and ARDS Receiving ECMO
ICU mortality lower compared with patients without obesity in multivariable and propensity score-matched analyses
Recurrent Injury, Death Common After Acute Firearm Injury
Individuals experiencing recurrent injury are typically young and mostly male, Black, and uninsured
ESC: Cumulative Sedentary Time in Younger Years Tied to Changes in Heart Structure
13-year findings reveal sedentary time from childhood through young adulthood associated with progressive left ventricular remodeling
Overestimation of Oxygen Saturation Leads to Delayed COVID-19 Treatment
Patients with unrecognized need for COVID-19 therapy appear to have higher odds of readmission, regardless of race
Mortality Risk Increased for Six Months After COVID-19 in Veterans
Those who survived COVID-19 had reduced mortality on days 181 to 365 and 366 to 730
Statin Exposure Not Linked to Increased Risk for Recurrent ICH
Survivors of spontaneous intracerebral hemorrhage with statin exposure have a lower risk for any stroke, ischemic stroke
Total Hip Arthroplasty Can Be Performed Safely in 90-Year-Olds
Comorbidities tied to higher rates of complications and postoperative morbidity
Some Immunosuppressed Do Not Have Anti-Spike Antibodies After COVID-19 Vaccination
IgG anti-spike antibodies undetectable in ~20 percent with immunosuppression who had received three or more COVID-19 vaccines
Hospital COVID-19 Burden Impacted NSTEMI Treatment, Outcome
Outcomes and treatment worse for patients hospitalized during weeks with a high hospital COVID-19 burden
Surgery for Isolate Cleft Palate at 6 Months Yields Better Outcomes Than at 12...
Benefits seen for velopharyngeal insufficiency at 5 years of age
No Change in Depression Seen in Children Across the Globe From 2004 to 2019
Findings based on 41 studies with data for children younger than 13 years old
Many Heart Attack, Stroke Survivors Do Not Know Their Cholesterol Levels
American Heart Association says knowing levels is key to preventing recurrent heart attack, stroke
Narcan Will Reach Drug Store Shelves Next Week
The nasal spray version of naloxone will be available at select retailers for $44.99 for a box of two doses
Adult Education Classes May Lower Dementia Risk
Additionally, participation tied to greater retention of subsequent fluid intelligence
ESC: Catheter Ablation Aids Symptomatic Atrial Fibrillation, End-Stage Heart Failure
Patient benefits seen for all-cause mortality, implantation of a left ventricular assist device, or urgent heart transplantation
Women’s Weight Loss Tied to Lower Odds of Living to 90 Years or Older
Three-year weight loss in older women tied to 33 percent lower odds of reaching age 90 years; association stronger for unintentional versus intentional weight loss
Higher Neighborhood Opportunity Tied to Lower Childhood Asthma Incidence
However, no association seen for social vulnerability index in early-life neighborhood