Inflammatory Heart Disease After COVID-19 Rare in Athletes
Five athletes (0.6 percent) had cardiac magnetic resonance imaging findings suggestive of inflammatory heart disease
New Models Predict Risk for Ventilation, Death From COVID-19
Age not a predictor of which hospitalized COVID-19 patients will require ventilation
Tobacco Exposure Tied to Hypertension in Children
Findings based on study of more than 8,500 children ages 8 to 19 years
Erythrocytosis ID’d in 11 Percent of Trans Men Using Testosterone
Factors associated with erythrocytosis include tobacco use, long-acting undecanoate injections, age at initiation of testosterone
Weight Loss Tied to Worse Breast Cancer Outcomes
Baseline body mass index tied to outcomes, with obesity linked to poorer outcome
Timing of Exercise May Be Linked to Cardiovascular Fitness
Associations significant for men with type 2 diabetes, but less so for women
Neurologic Involvement Common in Children Hospitalized With COVID-19
Twelve percent of those with neurologic involvement develop life-threatening conditions associated with COVID-19
FDA Warns Consumers to Not Use Ivermectin for COVID-19
Agency has received reports of patients requiring medical support after self-medicating with ivermectin for use in horses
Globalization of Cancer Trials Tied to Lower Enrollment of Blacks
Significant inverse correlation identified between proportion of patients enrolled outside the U.S. and disparity score
Suicide Decedents in Child Welfare System Had Used Health Services
Young suicide decedents more likely to have accessed mental health services, physical health services; visited ED
Physician’s Briefing Weekly Coronavirus Roundup
AI Algorithm May Differentiate Polyps on CT Colonography
Adding machine learning-based image analysis allows noninvasive differentiation of benign and premalignant polyps
Six in 10 Heart Failure Patients Readmitted Within One Year
Comorbidities, including kidney dysfunction, lung disease, and psychiatric illness, tied to higher readmission
Hypertensive Disorders of Pregnancy Tied to Heart Damage 10 Years Later
A decade after delivery, changes seen in left ventricular structure and function
2014 to 2019 Saw Increase in Prevalence of Autism in U.S. Children
From 2014 to 2019, prevalence remained stable among non-Hispanic Whites, while increases were seen in non-Hispanic Blacks, Hispanics
Ivermectin Does Not Speed Symptom Resolution in Mild COVID-19
No significant improvement seen in median time to resolution of symptoms with ivermectin versus placebo
Heart Failure-Related Mortality Up for Rural Versus Urban Adults
Rural-urban incidence rate ratio persisted among younger and older adults after adjustment for county-level factors
Delayed Local Reactions to mRNA-1273 Vaccination Reported
Reactions appeared near injection site at a median onset of day 8 after first dose; six of 12 patients had no recurrence after second dose
Two Cases of SARS-CoV-2 Variant P.1 Identified in Minnesota
Patients reported travel to Brazil within 14 days prior to symptom onset; genome sequencing confirmed specimens to be P.1 variant
Three Modes of Transmission Explain Most Giardiasis Outbreaks
Water exposure, person-to-person contact, contaminated food accounted for more than half of outbreaks in 2012 to 2017
Shortage of Syringes Reported for COVID-19 Shots
Billions poured into development of vaccines, but little public investment made in expanding manufacturing for syringes
Semaglutide May Aid Weight Loss in Obese Patients With T2DM
Estimated change in mean body weight to week 68 was −9.6 percent with semaglutide 2.4 mg versus −3.4 percent with placebo
Ambulatory Function Poorer for Older Cancer Survivors
Poorer ambulatory function associated with increased risks for mortality; significant associations seen for nine cancer types
Psychiatric Visits Increased Significantly in 2020 Versus 2019
7 percent increase found in psychiatric care volume overall, but 42 percent decrease seen for new patients
Frequency of Urgent Vitreoretinal Surgery Down During Pandemic
Decreases seen in intravitreal injections, lasers and cryotherapy, retinal detachment repairs, other vitrectomies
CVD Risk Factors Tied to Cognitive Impairment in Schizophrenia
Significantly greater global cognitive deficits seen in those with schizophrenia who had metabolic syndrome, diabetes, hypertension
Uptake of Seasonal Influenza Vaccine Lower Among Minorities
Uptake lower among Black, Asian, Hispanic adults versus Whites; those vaccinated less likely to receive high-dose vaccine
CV Risk Factors, Atherosclerosis May Alter Brain Metabolism
Cardiovascular risk, particularly hypertension, associated with brain hypometabolism in asymptomatic middle-aged adults
Maternal Cardiovascular Health in Pregnancy Tied to Offspring Cardiovascular Health
Maternal CV health at 28 weeks of gestation tied to offspring cardiovascular health at ages 10 to 14 years
Many Non-Whites Experience Discrimination in Alzheimer Disease Care
Overall, 36, 19, and 18 percent of Black, Hispanic, Asian Americans, respectively, believe discrimination is barrier to receiving care
Egg, Cholesterol Intake Linked to Higher Mortality
Increased mortality associated with egg consumption largely influenced by cholesterol intake
CDC: 21,869 West Nile Virus Cases Identified in U.S. in 2009 to 2018
59 percent were neuroinvasive disease cases, which occurred more often with increasing age
Emptier Roads, but Sharp Rise in U.S. Traffic Deaths Reported in 2020
NHTSA says speed is main problem, as well as increased use of alcohol, marijuana, and opioids
California Targets Vulnerable Neighborhoods for COVID-19 Vaccination
Neighborhoods considered highly vulnerable based on factors such as income, education, housing, and transportation
COVID-19 Death Rates 10 Times Higher in Countries Where Most Are Overweight
Higher BMI also associated with increased risk for hospitalization, ICU admission, need for mechanical ventilation
Pediatric Oncology Services Disrupted During Pandemic
Newly diagnosed pediatric cancer cases decreased in 43 percent of centers; treatment abandonment increased in 34 percent
Traumatic Brain Injury May Increase Risk for Sleep Disorder
Increased risk observed for any sleep disorder, including sleep apnea, insomnia, hypersomnia, sleep-related movement disorder
Premature Ovarian Insufficiency Linked to Osteoporosis
Current cigarette smoking influenced the association, and protective factors included obesity, current hormone therapy use
AAAAI: Peanut Allergy Down 16 Percent in Infants
After 2016 changes to feeding guidelines advising earlier introduction of peanut, prevalence of peanut allergy in infants has decreased
Terlipressin Bests Placebo in Type 1 Hepatorenal Syndrome
Terlipressin is more effective for reversal of HRS but is associated with more adverse events and death due to respiratory disorders
Women With T1DM Experience Shorter Reproductive Period
Women with type 1 diabetes experience 2.5 fewer reproductive years, with findings limited to women diagnosed before reaching menarche
American Indians Have Highest Risk for Nonhemorrhagic Stroke
American Indians have highest risk of nonhemorrhagic stroke compared with non-American Indians, in presence or absence of a-fib
County-Level Factors Affect Race/Ethnicity-Specific CVD Death
Greatest variation in CVD age-adjusted mortality rate explained by socioeconomic factors for non-Hispanic Blacks
New Algorithm Can Predict Advanced Liver Disease
The CIRRhosis Using Standard tests algorithm could use results of routine blood tests to identify those at high risk for advanced liver disease
Nivolumab Plus Cabozantinib Tops Sunitinib for Renal Cell Carcinoma
Combination therapy superior with respect to progression-free, overall survival and overall response for first-line treatment of advanced RCC
Behavioral Health Issues Remain High as Pandemic Continues
Survey results reveal self-reported mental health, substance use, and suicidal ideation among U.S. adults in September 2020
Patients’ Mental Health Impacts Rating of Psoriasis Severity
Likelihood of a patient overestimating their psoriasis severity versus physician increased for those with depression, anxiety
NIH Halts Trial of Convalescent Plasma for Mild COVID-19
While the treatment seemed safe, no significant differences in outcomes were seen between patients receiving convalescent plasma or placebo
USPSTF Urges Screening Young Women for Chlamydia, Gonorrhea
All sexually active women aged 24 years and younger should be screened as well as women older than 25 at high risk
Good Response Seen With HealthCare.gov Reopening
CMS figures show more than 206,000 people signed up for coverage from Feb. 15 to 28
Dysnatremia Tied to Poorer Prognosis in Hospitalized COVID-19 Patients
Hypernatremia linked to increased mortality, while hyponatremia at admission linked to increased odds of needing ventilatory support
Bone Density Testing Low in Veterans With Kidney Stone Disease
23.6 percent of those with kidney stone disease have prevalent diagnosis of osteoporosis or fracture
Costs of Eating Disorders Quantified for the United States
Total economic costs estimated at $64.7 billion for fiscal year 2018 to 2019; reduction in well-being costs estimated at $326.5 billion
AAN: Anomalously Warm Weather Tied to More MS Hospital Visits
Authors say absolute effect on people with multiple sclerosis and the health care system is meaningful
AAN: Antidepressants Not Tied to Increased Intracerebral Hemorrhage Risk
Selective serotonin reuptake inhibitors are not associated with higher risk for intracerebral hemorrhage
Provider Teams Outperform Solo Care for New-Onset Chronic Disease
Among solo providers, there was little difference in care management and outcomes between physicians, nonphysicians
Birth Weight Modifies Link Between Adult IGF-1 Levels, T2DM
IGF-1 levels inversely associated with T2DM risk in dose-dependent manner, but only among those with birth weight ≥2.5 kg
Prediabetes, Type 2 Diabetes Tied to Poorer Brain Health
Higher risk for cognitive decline, vascular dementia, Alzheimer disease seen with high blood glucose
Physical Activity May Cut Fatality Risk in Myocardial Infarction
Risks for instant death, 28-day death related to MI lower in those with moderate-to-high levels of past physical activity
Threshold ID’d for Urine Test to Rule Out Prostate Cancer
In validation study, 3.7 percent of grade group ≥2 cancers missed with MyProstateScore value ≤10
Preliminary Data in Israel Show COVID-19 Vaccines Effectively Prevent Severe Disease
National study shows reduction in ratio of COVID-19 patients requiring mechanical ventilation aged 70 years and older to those younger than 50 years
Umbrella Review Reveals Links Between Diet, Colorectal Cancer
Review of meta-analyses of prospective observational studies reveals lower risk with higher intakes of dietary fiber, dietary calcium, yogurt
Risk for Breast Cancer Death Increased With Missing Mammogram
Serial participants have significantly lower risk for death compared with those who missed one or both of two screenings before diagnosis
One-Third of U.S. Adults Continue to Be Hesitant About COVID-19 Vaccines
Rates of vaccine hesitancy particularly high among Black adults and Republicans, a December survey reveals
Dramatic Decline Seen in COVID-19 Cases, Deaths at U.S. Nursing Homes
82 percent decline reported in new COVID-19 cases among residents at nursing homes since the peak during the week of Dec. 20
Robotically Assisted Surgical Device Authorized for Transvaginal Hysterectomy
Hominis Surgical System granted marketing authorization approval for use in benign hysterectomy with salpingo-oophorectomy
Response to One Dose of COVID-19 Vaccine Strong for Previously Infected
Two studies show higher anti-S titers in those with previous infection and very strong T-cell responses
IL-6 Receptor Antagonists Benefit Critically Ill With COVID-19
Improved outcomes, including more organ support-free days, reduced mortality, seen with tocilizumab, sarilumab
Only Two in 10 Older Adults Report Being Screened for Hearing Loss
Half of older adults rate their hearing as excellent or very good
Layperson-Delivered Phone Intervention Eases Loneliness for At-Risk Adults
Reductions seen in loneliness, depression, and anxiety; improvement seen in mental health among at-risk adults
Mortality Lowest With Five Servings of Fruit, Vegetables/Day
Lowest mortality seen with two servings of fruit and three servings of vegetables; no additional risk reduction seen with higher intake
COVID-19 Outcomes No Worse for People With Asthma
Patients with asthma may have a lower risk for becoming infected
Prescription Opioid Misuse Tied to Increased Suicide Behaviors in Youth
Students who report current POM more likely to report considering attempting suicide, making a suicide plan, attempting suicide
Childhood ADHD May Raise Risk for Later Psychotic Disorder
Findings based on systematic review and meta-analysis of pooled data from 12 studies involving more than 1.85 million participants
High Dose of Vitamin D Does Not Cut COVID-19 Hospital Stay
No significant differences seen for other outcomes among patients hospitalized with moderate-to-severe disease
Text Reminders + Mailed Home Testing Up Colorectal Cancer Screening
Screening rates improved in patients due for testing at a community health center predominantly serving people of color
Sleep Deficiency, Disturbance Tied to Higher Dementia Risk
Older adults followed for five years with poor-quality sleep had higher risk for dementia, earlier death
ASH Issues Guidance for Preventing, Treating VTE in Cancer
Use of thromboprophylaxis not recommended for ambulatory patients at low risk for VTE who are receiving chemotherapy
High Glycemic Index Diet May Up Risk for CV Disease, Death
Diet with a high glycemic index linked to increased risk for major CV event, death for those with, without preexisting cardiovascular disease
Racial, Ethnic Disparities Found in Diagnosis, Treatment of ADHD
Asian, Black, Hispanic children less likely to be diagnosed than Whites; White children more likely to receive some treatment
AstraZeneca COVID-19 Vaccine Easy to Update in Response to Variants
Oxford team working on modifying vaccine to fight new variants, expects new version to be available in the fall
U.S. to Monitor Air Travelers From African Nations With Ebola
As of Feb. 25, Guinea had nine Ebola cases, five deaths; the Democratic Republic of the Congo had eight cases, four deaths
Walmart Expands COVID-19 Vaccination Program
Company will use COVID-19 vaccines supplied by the U.S. Centers for Disease Control and Prevention
J&J COVID-19 Vaccine Granted Emergency Use Authorization
The single-dose Ad26 vaccine is now the third COVID-19 vaccine to be granted an EUA
Axillary Adenopathy Reported After Recent COVID-19 Vaccination
Management approach to these findings includes axillary ultrasound if clinical concern persists six weeks after final dose of vaccine
Decline in U.S. Suicide Rates From 2018 to 2019 Not Uniform
Significant declines seen in five states and certain subgroups, but several states experienced significant increases
Cutaneous Findings Described for Children With MIS-C
Cutaneous findings varied among patients; annular plaques in the proximal medial lower extremities were common
Model Estimates Harm Attributed to Menthol Cigarettes
From 1980 to 2018, menthol cigarettes were responsible for 10.1 million extra smokers, 3 million life years lost, 378,000 premature deaths
Inappropriate Antibiotic Prescribing Common for Women With UTIs
Many women receive prescriptions for inappropriate agents or durations; rural women more likely to receive Rx with inappropriately long duration
Transplant Beneficial for Kidney Failure in Sickle Cell
Patients with kidney failure associated with sickle cell disease are less likely to receive a transplant despite similar reduction in mortality
U.S. Patterns for Recurrent Coronary Heart Disease Examined
Decreases in recurrent MI rates, recurrent CHD event rates, heart failure hospitalization rates, all-cause death greater in women than men
More Frequent Disinfectant Use Tied to Uncontrolled Asthma
Findings seen in a survey of U.S. adults with asthma during the COVID-19 pandemic
Optimal Therapy for Esophageal Cancer Feasible in Fit Elderly
Those 70 years and older have similar postoperative complication scores and long-term survival
Physician’s Briefing Weekly Coronavirus Roundup
Exposure to Greenspace Linked to Lower Risk for Pediatric-Onset IBD
Risk reduced for both ulcerative colitis, Crohn disease; linear dose response seen across increasing quartiles of greenspace
Markers of Puberty Differ in Girls With More Body Fat
Girls with higher total body fat have delayed breast maturation, as determined by breast ultrasound, and earlier menarche
Many Older Adults Keep and Use Leftover Antibiotics
Authors say further education is needed on appropriate uses of antibiotics
Digital Self-Monitoring Linked to Weight Loss for Adults
Few interventions had digital self-monitoring engagement rates greater than 75 percent of days
Cigarette Smoke Adds to Colorectal Neoplasia Risk in Patients With IBD
Adding smoke exposure improves the current risk stratification for colorectal neoplasia surveillance strategies
Online Portal Guides Users to COVID-19 Vaccination Sites Nationwide
VaccineFinder has been expanded to include more than 20,000 COVID-19 vaccination sites
Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility
Five patients tested positive in outbreaks in July and October 2020; disease severity worse during second outbreak
Model Can Aid Assessment of Multiple Pulmonary Nodules
Validated machine-based learning model performs better than surgeons, radiologists, CADx for predicting malignancy
Treatment to Lower RA Disease Activity Feasible in Pregnancy
In pregnant patients with rheumatoid arthritis, clinicians should strive for remission or low disease activity
Racial/Ethnic Minorities Underrepresented in Vaccine Trials
In adult trials, White patients and women are overrepresented; White patients account for 77.9 percent of participants
Mortality Gap Between Cancer, Heart Disease Narrowing for Women Younger Than 65
Age-adjusted mortality rates decreased for cancer and heart disease from 1999 to 2018, but increased for heart disease from 2010
Early-Onset T1DM Negatively Impacts Brain Development Over Time
Baseline differences in brain volumes and IQ persist or increase over longitudinal follow-up
Decline in Myocardial Function May Start Early in Blacks
Midwall fractional shortening trajectories differ by race from early age to young adulthood
COVID-19 Cases, Deaths Plummet in Nursing Homes After Vaccine Rollout
From late December to early February, new cases among U.S. nursing home residents fell by more than 80 percent
CDC Expands Alert About Listeria Outbreak Linked to Cheese
Three new illnesses linked to the outbreak reported this week
Liver Cancer Profile Differs in Black Patients With Hep C
Black patients have better liver function at the time of hepatocellular carcinoma diagnosis; have less early-stage HCC, larger tumors
U.S. Government to Distribute Millions of Face Masks
Masks will be sent to underserved communities and those hardest hit by the pandemic
Risk Reduced for Positive NAAT Result With SARS-CoV-2 Antibodies
Patients with positive antibody test initially more likely to have positive NAAT result but less likely after 30 days
New Coronavirus Variant Sweeping Through New York City
The new variant is called B.1.526 and was first detected in samples gathered in the city in November
More Than Half of U.S. Adults Use Dietary Supplements
Use higher for women than men; use increased with age, overall and in both men and women
COVID-19 Vaccine Makers Planning for Variants
Pfizer, BioNTech in discussions with regulators about testing an adapted version of their vaccine
Estimated Opioid-Related Costs $14 Billion for Symptomatic Knee OA
Almost half of costs were for lost productivity, criminal justice expenses, cost associated with diversion activities
AAN: Many Patients With Migraine Do Not Get Enough Exercise
Patients with no exercise report increased depression, anxiety, and sleep problems and have more migraines
USPSTF Recommends Low-Dose Aspirin to Prevent Preeclampsia
Substantial net benefit observed for daily low-dose aspirin use in pregnant women at high risk for preeclampsia
Time From eGFR Wait-List Threshold to ESKD Shorter in Blacks
Registering Blacks on transplant wait list at eGFR of 24 to 25 mL/min/1.73 m2 could improve racial equity in wait time prior to ESKD onset
Non-White Race Tied to Higher Likelihood of COVID-19 Infection
Age, not race, most important contributing factor for outcomes
AAN: Smell Loss Can Persist for Five Months After COVID-19
About half of those with compromised sense of smell during acute phase had not regained sense of smell at average of 150.1 days postdiagnosis
Symptoms ID’d That Should Trigger COVID-19 Testing
Testing people with any of seven key symptoms in the first three days of illness would detect 96 percent of symptomatic cases
Nationwide Study Shows BNT162b2 mRNA Vaccine Is Effective
In mass vaccination setting, vaccine is effective for symptomatic COVID-19, hospitalization, severe disease, death
FDA Review Reveals J&J COVID-19 Vaccine Safe, Effective
Advisory panel set to meet Friday to recommend whether the agency should authorize the shot for emergency use
Children Given Flu Shot Less Likely to Have Symptomatic COVID-19
Odds also lower for having severe disease for patients vaccinated for influenza, pneumococcal disease
Polynesian Ancestry May Increase Cardiometabolic Risk
Genetic study reveals link between Polynesian ancestry and higher risk for obesity, T2DM, heart failure in Native Hawaiians
New Coronavirus Variant Surging in California
The B.1.427/B.1.429 variant has been detected in 45 U.S. states to date and in several other countries
Pfizer, Moderna Tell Congress a Big Jump in Vaccine Supply Is Coming
By end of March, Pfizer and Moderna expect to have delivered a total of 220 million vaccine doses to the U.S. government
Pessary Treatment Successful for Symptomatic Pelvic Organ Prolapse
75.3 percent of patients report successful pessary treatment at five-year follow-up, with discontinuation rates decreasing over time
Use of Health Services Up for Adults With Inflammatory Bowel Disease
IBD associated with increased prevalence of being prescribed medication and having received acute care services
Pediatric-Onset Multiple Sclerosis Tied to Lasting Social Consequences
Long-term follow-up shows lower educational attainment, lower income in adulthood
FDA: New Variants Mean COVID-19 Vaccines, Tests May Need Tweaking
Agency offers recommendations for companies seeking to modify already-approved vaccines, medicines, and tests so they can remain effective
Risk for Rheumatoid Arthritis Reduced for Patients With T2DM
Reduced risk may be attributable to statin use; no significant association seen for glycemic control, metformin use on RA risk
Text Message System Useful for Monitoring Postoperative Opioid Use
System deployed in 2,444 patients during 16-month period showed that 61 percent of opioid tablets remained unused
Children Conceived by ART Are Shorter, Lighter at Birth
Children conceived by assisted reproduction technology grow more rapidly after birth; height, weight similar to those naturally conceived by 17
Cocaine Use, HIV Affect Coronary Plaque Morphology
Cocaine use significantly linked to 23.7 percent of radiomic features identified in plaque; HIV infection linked to 1.3 percent
Deceased Organ Donation Rose Among Blacks but Still Lags
Despite gains in deceased organ donation among racial/ethnic groups in the U.S., substantial racial differences remain
Fecal Transplant May Counter Anti-PD-1 Resistance in Melanoma
FMT plus anti-PD-1 therapy may change gut microbiome and help overcome drug resistance in some patients with advanced melanoma
Prevalence of Multiple Chronic Conditions Up Among Veterans
Prevalence of MCC remained higher for male, female veterans after stratification by age and adjustment for sociodemographics
Vascular Deaths Down for Diabetes Patients in the U.K.
Cancer is now the leading contributor to death among individuals with diabetes living in England
FDA Warns Not to Rely on Pulse Oximetry for Diagnosis, Treatment Decisions
Safety communication follows NEJM study showing risk for inaccuracy with use of pulse oximeters in those with dark skin pigmentation
Transplant Recipient Dies After Receiving COVID-19-Infected Lungs
Surgeon who handled the donor lungs also became infected and fell ill but recovered
Trial of Gene Therapy for Sickle Cell Disease Halted
Two patients participating in the study developed cancer years after treatment
COVID-19 Vaccines Adapted to Fight Variants Will Not Require Long Clinical Trials: FDA
Most makers of approved COVID-19 vaccines have said they plan to adapt their vaccines to tackle variants
Amoxicillin-Clavulanate Effective for Outpatients With Diverticulitis
As effective as metronidazole with fluoroquinolone, with reduced risk for one-year Clostridioides difficile infection
Predictors of Death, Discharge ID’d for Diabetes Patients With COVID-19
Younger age, routine metformin therapy, and longer symptom duration on admission positively linked to discharge
Limiting Resident Shifts Cuts Attentional Failures in PICU
After adjustment for workload, rapid cycling work roster schedule has protective effect on rate of serious medical errors
Greater HbA1c Variability May Raise Risk for CVD in T2DM
Severe hypoglycemia may mediate this association
CDC Report Shows No Evidence of Unexpected Adverse Events With COVID-19 Vaccines
Findings from the first month show no unexpected adverse events, with 6,994 adverse events and >90 percent classified as nonserious
SARS-CoV-2, COVID-19 Rates Decreased After One Vaccine Dose
Study among health care workers shows reductions in SARS-CoV-2 infection rates one to 14, 15 to 28 days after first dose of the BNT162b2 COVID-19 vaccine
COVID-19 Vaccine Efficacy Higher With Three-Month Interval Between Doses
For ChAdOx1 nCoV-19 Oxford vaccine, three-month interval results in higher efficacy than six-week interval
Persistent Symptoms Reported for About 30 Percent With COVID-19
At least one persistent symptom reported by 32.7 percent of outpatients with mild illness, 31.3 percent of patients hospitalized
Prevalence Data Suggest Increasing Trend of Psoriasis With Age
Worldwide studies suggest stable or slightly decreasing trend in incidence of psoriasis and increasing trend in prevalence
Testosterone Therapy Does Not Improve Vascular Function
Exercise training, but not testosterone, improves endothelium-dependent vascular function in men with low-normal testosterone
Listeria Outbreak Spurs Recall of Queso Fresco Cheeses
There have been seven illnesses reported so far; all patients were hospitalized
GERD Linked to Squamous Cell Cancers of Larynx, Esophagus
An estimated 16.92 and 17.32 percent, respectively, of cases of LSCC and ESCC among individuals aged 50 to 71 years linked to GERD
All British Adults Should Have First COVID-19 Shot by July 31: Government
Announcement made as government prepares a 'cautious' reopening plan
Proinflammatory, Low-Quality Maternal Diet Linked to Adiposity
Odds of late childhood overweight and obesity increased with more proinflammatory diet in early pregnancy
Bone Cancer Survivor Selected for SpaceX Flight
Hayley Arceneaux will join billionaire Jared Isaacman, who wants to raise $200 million for St. Jude Children's Research Hospital
U.S. COVID-19 Hospitalizations at Lowest Level Since November
There were about 59,800 COVID-19 patients in hospitals nationwide on Friday, a 55 percent decrease from Jan. 6
Aspirin Overused, Statins Underused for CVD Prevention in Seniors
56.4 percent aged 75 years and older using statin for secondary cardiovascular event prevention; 45.3 percent taking aspirin for primary prevention
Physician’s Briefing Weekly Coronavirus Roundup
Mortality Highest for Asians, Hispanic/Latinos With Lupus
Among patients with systemic lupus erythematosus, mortality is increased for minorities, especially Asian, Hispanic/Latina women
Pediatric Inpatient Admissions Down During Pandemic
Findings seen across a wide range of diagnoses and not reflective of seasonal variation
Socioeconomic Status Tied to Multisystem Inflammatory Syndrome in Children
Low socioeconomic status, high social vulnerability index, racial/ethnic minority linked to MIS-C
Factors Associated With Fracture Risk in Middle Age ID’d
Factors independently linked to incident fracture include age, sex, BMI, level of leisure-time physical activity
Among Blacks, Late-Stage HIV Diagnosis Varies by Rurality
Across rural, urban, metropolitan areas, linkage to care within one month of diagnosis was similar but below targets
U.S. to Provide $4 Billion for International COVID-19 Vaccine Program
U.N. Secretary-General Antonio Guterres says that 130 countries have not received a single dose of the vaccine
Lenvatinib Plus Pembrolizumab Tops Sunitinib in Advanced RCC
Progression-free, overall survival significantly longer with combo versus sunitinib for advanced renal cell carcinoma
Pfizer to Begin Clinical Trial of COVID-19 Vaccine in Pregnant Women
Pfizer also planning to start trials of the vaccine in younger children, teens, people with weakened immune systems
Age-Adjusted Suicide Rates Decreased From 2018 to 2019 in U.S.
2019 rates significantly lower in women aged 25 to 44 years and in boys and men aged 10 to 14, 45 to 64, and 65 to 74 years
Water Problems Plague Texas Hospitals After Storm
Hospitals experiencing water pressure issues as well as widespread power outages
Discharge to Survival After Out-of-Hospital Cardiac Arrest Lower for Women
Among patients who were not made DNR and did not have withdrawal of life-sustaining therapy, women had lower discharge survival
T2DM in Middle Age Ups Mortality Risk in COVID-19 Infection
Excess COVID-19 death risk from type 2 diabetes decreases with increasing age
COVID-19 Death Count Varies With Race of Nursing Home Residents
Nursing homes with lowest versus highest proportion of White residents have higher COVID-19 death counts
Scoring Tool Predicts Seven-Day Stroke Risk After TIA
Risk prediction using Canadian TIA Score accurate with or without carotid endarterectomy/carotid artery stenting
Genetic Mutations May Add to Racial Disparity in Child B-ALL
Increased incidence of IKZF1 deletion and IGH-CRLF2 translocation seen in Hispanic/Latino children with B-ALL
Age, Frailty Independently Linked to COVID-19 Mortality
Frailty also associated with increased risk for higher care needs on discharge and increased likelihood of adverse outcomes
Many U.S. Troops Refusing COVID-19 Vaccination
Up to two-thirds of troops who were offered the vaccine have accepted, according to 'very early data'
Dementia Risk Up in Men With Genetic Mutation for Hemochromatosis
Male p.C282Y homozygotes have lower T2* measures on brain MRI in areas including the putamen, thalamus, hippocampus
Millions of Counterfeit N95 Masks Seized
Medical workers and companies should go to the 3M website to learn how to identify fake masks
Certain Prostate Drugs Tied to Risk for Parkinson Disease
Use of glycolysis-enhancing drugs terazosin, doxazosin, or alfuzosin tied to lower risk for developing Parkinson disease than use of tamsulosin
FDA Approves Therapy to Protect Bone Marrow Cells From Effects of Chemotherapy
Cosela reduces the frequency of bone marrow suppression caused by chemotherapy for extensive-stage small cell lung cancer
Decrease Seen in U.S. Life Expectancy in First Half of 2020
Life expectancy decreased by 1.0 year in first half of 2020 from 2019, with decreases of 1.2 and 0.9 years for males and females, respectively
Myocardial Injury Prevalent in Patients With Severe COVID-19
54 percent of discharged patients who had troponin elevation in conjunction with severe COVID-19 had late gadolinium enhancement and/or ischemia
Relugolix Combo Therapy Beneficial for Fibroid-Related Menorrhagia
Significantly more women had reduced menstrual bleeding with once-daily relugolix combination therapy versus placebo
Avacopan Noninferior to Prednisone for ANCA-Associated Vasculitis
Avacopan noninferior to prednisone taper for remission at week 26, superior to prednisone taper for sustained remission at week 52
1998 to 2018 Saw Jump in Admissions for Food-Induced Anaphylaxis
U.K. data revealed decrease in case fatality rate during study period; cow's milk responsible for 26 percent of deaths in school-aged children
Biomarker May Predict Treatment Outcome in Advanced Melanoma
Changes in plasma levels of ctDNA associated with survival outcomes in BRAF V600 mutation-positive unresectable or metastatic melanoma
White Matter Hyperintensities Characterized in Dementia
Association seen for larger volumes of white matter hyperintensities with disease severity, but not vascular risk, in bvFTD
Enfortumab Vedotin Prolongs Survival in Advanced Urothelial Cancer
Overall survival longer compared with standard chemo for disease progression following platinum-based chemo and PD-1 or PD-L1 inhibitor
Mortality Lower for Veterans Receiving Posttransplant Care in VA
Mortality significantly higher for patients receiving care after kidney transplant in Medicare only, dual care
Zinc, Ascorbic Acid Do Not Cut Symptom Duration in SARS-CoV-2
No difference in length of time required to achieve 50 percent reduction in symptoms seen with supplements versus usual care
Methylprednisolone Added to IVIG May Cut Fever in MIS-C
IV immunoglobulins plus methylprednisolone associated with lower risk for treatment failure compared with immunoglobulins alone
Cabozantinib Prolongs PFS in Papillary Renal Cell Carcinoma
Progression-free survival longer and response rate greater for cabozantinib versus sunitinib in phase 2 trial in adults with PRCC
CPR Quality Impacts Survival in In-Hospital Cardiac Arrest
Number of pauses greater than 10 seconds during resuscitation linked to survival for four end points
Primary PCI Use Down for Cancer Patients With STEMI
Rates of associated in-hospital all-cause mortality, major adverse cardiovascular and cerebrovascular events lower for cancer patients
CRISPR-Based Testing Feasible for SARS-CoV-2 Screening
Study finds technology shows concordance with PCR testing and can detect leading edge of outbreak in asymptomatic people
Canadian Study Confirms COVID-19 More Serious Than Influenza
Relative risks increased for in-hospital mortality, ICU use, hospital length-of-stay during first wave of pandemic