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Tapering cuts risk for overdose among those with opioid use disorder

Findings include worse brain white matter microstructural integrity, reduced cortical grey matter thickness, and decreased functional connectivity

Furthermore, consistency of lung cancer may be an important predictor of survival

Findings seen at 30-year follow-up of patients who underwent breast-conserving surgery, systemic therapy for early-stage breast cancer

ACR Convergence 2022

Mpox incidence was 9.6 times as high among unvaccinated persons than among those who had received two vaccine doses

Industries with highest proportionate mortality ratios were mining, accommodation and food services, construction

Serious adverse events are rare in adults, and none have been identified among persons aged younger than 18 years

Updated boosters protect against both the original strain of COVID-19 and highly contagious omicron variants

New guidance says complications can include dry eyes, double vision, difficulty with night driving, chronic eye pain

Fewer men in experimental group received diagnosis of clinically insignificant prostate cancer

Significantly longer progression-free survival seen with infusion of tumor-infiltrating lymphocytes versus ipilimumab

n-3 fatty acid supplementation may reduce CVD mortality, myocardial infarction, coronary heart disease events

Deductible payments discouraged women from returning for diagnostic workup of abnormal screening results, caused them to skip screening

Findings in Brazil similar to those in countries with a high prevalence of Crohn disease

Faster rates of global cognitive decline, executive function decline observed for those with ultraprocessed food consumption above first quartile

Significant positive association seen between daily cost of parking and cost of living in city and for cancer center address transit score

Markedly elevated risk seen for ACPA-positive RA with exposure to any occupational inhalable agents, smoking, high genetic risk score

A considerable proportion of ulcerative colitis, Crohn disease cases could be prevented by adherence to low modifiable risk score, healthy lifestyle

Adjusted odds highest for sleep-related suffocation, unexplained infant death for infants not sharing room with mother, caregiver

Educational intervention and making ear probes available in critical care setting increases compliance with manufacturer guidelines

More frequent surveillance not linked to longer recurrence-free, overall survival in pathologic stage I non-small cell lung cancer

Rate of BP control significantly higher after 12 months of multicomponent intervention, with reduction in SBP of −10.1 mmHg

Risk reduced for lobar and nonlobar intracerebral hemorrhage; greater reductions seen with prolonged use ≥5 years

Findings show protection for all variant periods

Program needs an overhaul with greater attention paid to strong leadership and a more proactive culture

At this point, about 6 million Americans have taken free Paxlovid doses

SGLT-2is associated with lowest probability for adverse outcomes followed by glucagon-like peptide-1 receptor agonists, metformin

Number of twin births declined 7 percent compared with 3 percent decline in singleton births

However, those with persistent pain were no more likely to experience cognitive decline

The 2022 Annual Scientific Meeting of the American College of Allergy, Asthma & Immunology

Results similar for DASH or fruit and vegetable diets versus typical American diet

Authors hope findings will reduce disparities in surgical access for minority children and raise awareness among clinicians

At three years, test identified more advanced precancerous lesions than expected

Largest declines seen among Black individuals, young people, and those without insurance

Resources require high literacy levels and often lack translation to other languages

Significantly greater decreases seen in HbA1c levels, LDL-C levels, and systolic BP for team-based care with versus without CDSS

Reduction seen in rate of admissions due to cardiac disorders, renal and urinary disorders, metabolism and nutrition disorders, neoplasms

Overdose mortality increased about 81 percent from 2017 to 2020 among pregnant and postpartum women

Individuals who were independently aware of the FDA decision demonstrated reduced willingness to participate

Children in most optimal HbA1c quintile had substantially better educational attainment, while those in least optimal quintile had worse attainment

However, scar located on lower lid mid subunit perpendicular to facial tension lines was rated as less attractive

Easier access to birth control helps women who live far from a health care provider or have difficulty obtaining appointments

Improvements seen in blood pressure and central and peripheral aortic stiffness and pressure hemodynamics in teens with type 1 diabetes

Furthermore, use of devices linked to 3 percent improvement in cognitive test scores in the short term

Significant reduction seen in mortality rate from 2013 to 2017, after the introduction of new treatments in 2011 (most after 2013)

Increased cancer-specific mortality seen with heat-based thermal ablation versus cryoablation for tumor size 3.1 to 4 cm

Reduction seen in rate of one or more opioid days and in the rate of one or more pain-related hospital events

At the end of one year, likelihood of being weaned off treatment was higher for eyes treated with aflibercept versus bevacizumab

Odds are disproportionately increased with annual household income <$50,000; are reduced with performance of MVPA

However, Black, Asian, Hispanic women all more likely than White women to experience severe hypertension requiring treatment

Association especially strong among the elderly male population

Drift in model calibration performance was detected immediately, with minor fluctuations in discrimination

Decrease seen in HIV tests performed, persons prescribed PrEP, HIV diagnoses in quarter 2 of 2020, but partial rebound observed in Q3

25.5 percent of those whose serology indicated past infection reported not having been vaccinated, with higher rates seen in young, Black adults

Vaccination will be key to keeping patients healthy through the winter holidays

Though children aged 5 years and older and adults need only two doses to complete a primary series, younger children need three doses

Eleven customers have reported Pseudomonas infections; company investigating possible connection to the recalled products

Immunocompromised patients can still receive convalescent plasma

More than 29,000 Americans contracted the virus and 17 died during an outbreak that started earlier this year

Posthospitalization prevalence of residual lung abnormalities estimated at 11.7 percent in sensitivity analyses

MethHF linked to significant morbidity, including worse heart failure symptoms compared with non-methamphetamine-related heart failure

Odds of acute kidney injury, myocardial injury, lung injury increased for those exposed to supraphysiological oxygen

Performance similar to the standard atherosclerotic cardiovascular disease risk score

Findings seen even when accounting for sociodemographic factors, comorbidities, and smoking

Lack of knowledge, decision-making difficulties among factors identified with non-follow-up

Meta-analysis shows no significant associations for children, adolescents, or adults, for female patients, or for those with preexisting CVD

Sleeve gastrectomy tied to lower health care utilization, but five-year death, complications, reoperation, revision similar to gastric bypass

Excess risk for breast cancer remains elevated through 20 years for women with benign breast disease on screening

Smoking cannabis during pregnancy fourfold more likely under medical and adult-use legalization frameworks

Long-term risks for stroke and coronary heart disease increased for individuals with history of herpes zoster versus those with no history of herpes zoster

Cannabis use linked to reduced graft patency, increased amputation, and increased opioid use after lower-extremity bypass

Increased risk seen for nonscreenable cancers

Hotline started in July with mental health counselors working around the country and has answered about 8,000 calls a day since then

Monthly treatment costs of biosimilars were higher in the United States than corresponding costs in Germany, Switzerland

Type 2 diabetes risk factors were predominant for diabetes occurring before chronic pancreatitis

Few facilities report having environmental sustainability strategy in place or undertaking sustainability audits

In age-matched analysis, marijuana smokers had higher rates of bronchial thickening, bronchiectasis, mucoid impaction than tobacco-only smokers

Prevalence ratio of 1.28 found for diabetes with highest versus the lowest quintile of exposure to light at night

Heightened risk seen particularly for surgery for pelvic organ prolapse and urinary incontinence

Moderately less decline seen in cognition and function at 18 months with lecanemab versus placebo

Conversations less often about flu or COVID-19 vaccines versus school-required vaccines

Global goals include reaching UNAIDS targets for reducing new infections and reaching targets for all age, gender, and population groups

Rebyota is prepared from human stool donated by qualified individuals

Administration says it expects to issue updated draft guidance in the coming months

Agency says information could be used to target vaccination efforts and rapidly increase coverage if needed

Adjusted predicted probabilities of being aware of alcohol-cancer link higher for those believing alcohol increases heart disease risk

Greater decrease seen in nigrostriatal iron content with deferiprone, but more patients have symptom progression leading to initiation of dopaminergic therapy

SCD associated with increased rates of incident dementia over time in multiracial population, Latinx, non-Latinx Black individuals

Risk for preterm birth, small size for gestational age, low birth weight lower for those receiving buprenorphine versus methadone

Corticosteroids linked to progression of knee OA based on whole-organ magnetic resonance imaging scores, KL grade

Risk for recurrent venous thromboembolism reduced for patients with isolated distal DVT receiving six additional weeks of rivaroxaban

No significantly increased risk seen for ADHD or ASD with exposure to benzodiazepines during first, second, third trimester

One week of extended-release morphine does not significantly reduce the intensity of worst breathlessness

No significant causal effects were identified for other blood pressure traits with psychological states

Improvement in mean Boston Carpal Tunnel Questionnaire persisted at weeks 12 and 24; lasting reduction seen in median nerve cross-sectional area

Clinician nudge alone or in combination with a patient nudge increases initiation of statin prescribing versus usual care

COVID-19 may lead to new or worsening urinary symptoms in men and women

For men aged 65 to 74 and 75 years or older, drug overdose death rates were higher for non-Hispanic Black men

Program reduces frequency of long glances and lessens variation in lane position compared with control program

Use of most new-to-market meds was <20 percent; costs for these medications were substantially larger

Outcomes improved from Adaptive COVID-19 Treatment Trial-2 to ACTT-3, although potential explanatory factors were similar

National Return-to-Screening collaborative linked to improvements in cancer screening compared with prepandemic, pandemic periods

Catheter pump system capable of CED of topotecan well tolerated and active in recurrent glioblastoma

YLL increased 35.7 percent per COVID-19 death in 2021 versus 2020 as median age of COVID-19 deaths decreased

Caregivers with approach-oriented coping strategy have less anxiety and depression symptoms, better quality of life

Doctors suspect that by stripping away amyloid deposits, lecanemab weakens blood vessels and leaves them vulnerable to bleeds

No significant difference seen with medical masks versus N95 respirators for health care personnel providing care to COVID-19 patients

Lowest CVD risk seen for those who combined a DASH-style diet with lowest frequency of adding salt to food

After adjustment for confounding variables, risk of endometrial cancer was increased almost fourfold with tamoxifen treatment

Mean length was 10.7 years by the prevalence/incidence method and 10.1 years by the Markov chain Monte Carlo model method

Higher risk of cerebral palsy in offspring seen for severe injuries that resulted in hospitalization, delivery within one week from injury

7.4 year gain in event-free survival for 50-year-old patients with combo therapy with ACEi/ARB and SGLT2 inhibitors

More than twofold increased risk of prostate cancer seen for men with first melanoma diagnosed 10 to 15 years before study recruitment

However, total adverse events occur more often in patients receiving antidepressants versus placebo

Diagnosis and testing should be considered in patients with suggestive illness in regions that are hyperendemic for dimorphic mycoses

5.4 percent decrease seen in probability of any organ placement at age 70 versus 69 years

During 2017 to March 2020, only 8.3 percent of U.S. adults had tried to follow the recommendations of MyPlate

Maximum rates of firearm homicides higher among non-Hispanic Black and Hispanic versus White men

Portion of cup that contains lead was not tested in a safety lab because it was not meant to be exposed under normal use

New omicron subvariant is taking hold in the United States, health officials say, though it does not look more severe than its predecessors

Virus has been called monkeypox since 1958, when it was first observed in Denmark in research monkeys

Hospital-wide POCUS committee should be established, have oversight responsibilities for implementation and QA of POCUS program

Benefits include decreased need for routine factor IX replacement prophylaxis and reduction in annualized bleeding rate

Quality of life favored the pembrolizumab arm versus standard-of-care arm receiving ipilimumab, high-dose interferon α 2b

No influence seen on height for age, BMI for age, waist-to-height ratio, percentage body fat, fat mass, fat-free mass, or Tanner scores

Relaxation of restrictions coincided with increasing incidence of COVID-19, non-COVID-19 ARI, severe asthma exacerbations

Findings similar across most races and cancer stages from 2012 to 2019

Findings even stronger for young people with a recent opioid prescription

Authors say dental-medical history should include e-cigarette, vaping use

Overall survival and cumulative incidence of death related to tumor recurrence similar to open resection

Risk for adverse pregnancy outcomes not increased for those conceiving within three months after miscarriage, induced abortion

Sotrovimab effective compared with molnupiravir; second study shows no effect for angiotensin receptor blockers in terms of illness severity

Risk for aging-related health conditions increased with consumption of more total sugar, added sugar, and sugar-sweetened beverages

Persistent asthma linked to carotid plaque, total plaque score, even after adjustment for baseline interleukin-6, CRP

Among young male adults, those with MetS at three health checkups had nearly fourfold increased risk for incident gout

Five-year overall survival 47.3 percent in patients with lower-risk myelodysplastic syndromes

Researchers find acupuncture has no observable severe adverse influences on newborns

Findings seen versus nonsurgical care among individuals with severe obesity and nonalcoholic fatty liver disease

Physical activity in the morning reduces risk for CVD, regardless of total activity level; findings more evident in women

Less pneumonia, fewer cardiovascular events, deaths, hospitalizations seen during peak flu season

The American Heart Association Scientific Sessions 2022

Compliance with diagnostic and therapeutic indicators was 83 and 78 percent, while compliance with monitoring indicators was lower

Improvements seen in pain scores for patients receiving genicular nerve block at two, four, eight, and 12 weeks

Risk for diabetes lower with higher 25(OH)D in Jackson Heart Study and Multi-Ethnic Study of Atherosclerosis

Kidney Week 2022

Mutations identified in MUTYH, in the MLH1 gene, and in other cancer predisposition genes

Genotype by education interaction identified for five genetic variants, with increased effect for university-level education

Task force recommends screening asymptomatic adults at increased risk for latent TB infection

Beneficial associations seen for dietary intakes of total flavonols and several flavonol constituents

However, screening of high-risk individuals for lung cancer is still low at 5.8 percent nationally

Rates of scheduling and completion of well-child visits increased regardless of whether messages were standard or tailored

Pancreatic Cancer Action Network survey revealed knowledge gaps exist across ages, genders

Deaths associated with these pathogens comprised 13.6 percent of all global deaths, 56.2 percent of all sepsis-related deaths

Cognitive scores were lower in iron-deficient children after intervention, despite improvement in serum ferritin

High HDL-C is not protective against coronary heart disease in either White or Black adults

In patients receiving autologous stem cell transplant, 57.6 percent advanced to second-line treatment, 32.6 percent to third-line

Different results of MV ratio and cVEMP seen between TVV cases with and without central nervous system symptoms

Both metabolic syndrome components and related medical conditions seen at similar rates between patients with, without isolated nail psoriasis

Metastasis-directed therapy can delay initiation of systemic therapy in patients with solitary oligorecurrent metastatic lesion

Thermal images taken in home settings at week 0 can discriminate healed from unhealed leg venous ulcer wounds

Risk for developing dn-PPHTN was increased for those aged 35 years or older, with caesarean delivery, for current or former smokers

Overall improvement in quality-of-life measures sustained, without any progressive or delayed complications

Socially disadvantaged children less likely to receive treatment for recurrent or suppurative otitis media

Mental health workforce shortage linked to increased suicide rate and increased youth firearm suicide rate

Either PRIORIX or M-M-R II may be administered in any situation in which MMR vaccine is indicated

Researchers found that few individuals with psychotic disorders have participated in vocational training

Percentage of participants recruited from low-, middle-income countries was 8, 36, and 17 percent for cancer, cardiovascular, neurology trials

Supplements reduce risk among children with low serum 25(OH)D and have beneficial effects in children with atopic dermatitis, allergic rhinitis

However, opioids and NSAIDs carry similar cardiovascular, mortality risks for RA patients

United States has already seen 38,000 hospitalizations for flu; hospitals also treating high numbers of patients with RSV and COVID-19

Differences in youth preferences and emotional reactions seen across sex, sexual orientation, race/ethnicity, and weight status

Overall incidence of treatment-related adverse events was 91.2 percent and included lymphopenia, nausea, neutropenia

A patient- and family-centered care team should be established by engaging pediatricians with the family and specialists

Exposure-adjusted incidence rates of serious adverse events 8.5 versus 11.2 per 100 patient-years for anifrolumab versus placebo

Both weight-based and non-weight-based low-dose HCQ associated with increased hospitalizations for SLE

Short sleep duration and daytime napping associated with Crohn disease and ulcerative colitis

Findings based on primary composite outcome of IBD-related hospitalization or surgery with 394 days of median follow-up

Pregnancy can exacerbate certain conditions, including Meniere disease and benign paroxysmal positional vertigo

12.8 percent of children with familial high risk for schizophrenia, bipolar disorder transition to different neurocognitive subgroup

Psychologists report increases in those seeking care for anxiety, depression, substance use and no capacity for treating new patients

Tzield targets the autoimmune issues that drive the disease, rather than its symptoms

In early data, new Pfizer COVID-19 boosters marshal antibodies against newer omicron variants

Red flags include pharmacies that do not require a doctor's prescription or have a licensed pharmacist to answer questions

Emergency declaration would have allowed a more flexible response by pediatric practices and for FEMA assistance

Risk score model yielded nearly 100 percent prediction accuracy of 13-year dementia risk

Presence of HRVD can be identified in model including SDD, high-density lipoprotein with accuracy of 78.5 percent

Lower screening rates for cervical, breast, and colorectal cancers suggest 'pattern of forgone care,' according to researchers

Authors say immune response similar for patients holding methotrexate for one week or two weeks

Associations seen for temperature extremes and variability with stroke, migraines, hospitalization in dementia, MS exacerbations

Association mainly independent of preterm or SGA birth, may be partly explained by unmeasured familial factors

69.9 percent of sample reported acute physical health effects; 2.3 percent reported need for subsequent medical attention

AIAC group had lower adenoma and polyp detection rates; lower median number of adenomas, polyps detected per colonoscopy

Findings with preoperative radiotherapy administered to dose of 42.75 Gy in 15 fractions for three weeks

Global seroprevalence from infection or vaccination reached 59.2 percent by September 2021

Article describes inadequate oversight relating to development of COVID-19 vaccines and predating the pandemic

Prevalence of suicidality, self-harm increased for children with gender dysphoria-related diagnoses in 2016, 2019

Rates increased for women of all races, earning nation D+ grade, according to the March of Dimes

Normal EEG consistent with consciousness emerged as long as 35 to 60 minutes into CPR despite marked cerebral ischemia