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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of June 8 to 12, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

Oral Polio Vaccines Might Protect Against New Coronavirus

FRIDAY, June 12, 2020 (HealthDay News) — Oral polio vaccines might provide temporary protection against the new coronavirus while scientists try to develop a vaccine to fight COVID-19 infection, according to a perspective piece published in the June 12 issue of Science.

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PPE Supplies Sent by FEMA to Nursing Homes Often Defective

FRIDAY, June 12, 2020 (HealthDay News) — A Trump administration plan to boost nursing homes’ supplies of personal protective equipment is falling short, critics say.

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Stay-at-Home Orders Challenging Obese Patients

FRIDAY, June 11, 2020 (HealthDay News) — Obese patients are reporting physical and mental health challenges during the COVID-19 stay-at-home orders, according to a study published online June 9 in Clinical Obesity.

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Many of the Initial COVID-19 Treatment Trials Poorly Designed

FRIDAY, June 12, 2020 (HealthDay News) — Many clinical trials for COVID-19 treatments are limited by their design, with one-third excluding clinical end points, according to research published online June 9 in BMJ Open.

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Risk or Fear of COVID-19 Should Not Delay Bystander CPR

FRIDAY, June 12, 2020 (HealthDay News) — Bystander cardiopulmonary resuscitation remains a vital, lifesaving endeavor for out-of-hospital cardiac arrest, even during the COVID-19 pandemic, according to a study published online June 4 in Circulation.

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Signs, Symptoms Vary Widely for Children Presenting With PIMS-TS

FRIDAY, June 12, 2020 (HealthDay News) — Children presenting with pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 have a wide range of presenting symptoms, according to a study published online June 8 in the Journal of the American Medical Association.

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Cesarean Delivery Tied to Clinical Deterioration in SARS-CoV-2

FRIDAY, June 12, 2020 (HealthDay News) — Cesarean birth is associated with clinical deterioration in women with severe acute respiratory syndrome coronavirus 2 and with an increased risk for neonatal intensive care unit admission, according to a research letter published online June 8 in the Journal of the American Medical Association.

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First Large Clinical Trial of COVID-19 Vaccine in U.S. Could Begin in July

THURSDAY, June 11, 2020 (HealthDay News) — A large clinical trial of the first U.S. COVID-19 vaccine could begin next month, according to Moderna Inc., which developed the vaccine with the U.S. National Institutes of Health.

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Woman With Severe COVID-19 Receives Double-Lung Transplant

THURSDAY, June 11, 2020 (HealthDay News) — A young COVID-19 survivor received a double-lung transplant to save her life in what is believed to be the first such surgery in the United States, Northwestern Medicine doctors report.

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COVID-19 Behavior Seems Consistent With Seasonal Virus

THURSDAY, June 11, 2020 (HealthDay News) — Eight cities with substantial community outbreaks of COVID-19 are distributed along restricted latitude, temperature, and humidity measurements, consistent with behavior of a seasonal respiratory virus, according to a study published online June 11 in JAMA Network Open.

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Face-Mask Use by Public Can Mitigate Spread of COVID-19

THURSDAY, June 11, 2020 (HealthDay News) — Face-mask use by the public, in combination with physical distancing and periods of lockdown, can mitigate the spread of the new coronavirus, according to a study published online June 10 in the Proceedings of the Royal Society A.

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Personal Protective Equipment Prevents SARS-CoV-2 Infection

THURSDAY, June 11, 2020 (HealthDay News) — Appropriate personal protective equipment can protect frontline health care professionals who care for patients with severe acute respiratory syndrome coronavirus 2 infection, according to a study published online June 10 in The BMJ.

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~18 Million at Increased COVID-19 Risk Underinsured in U.S.

THURSDAY, June 11, 2020 (HealthDay News) — A total of 16.9 percent of those at increased risk for severe COVID-19 were inadequately insured at the start of the outbreak, according to a study published online June 10 in the Journal of General Internal Medicine.

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Acalabrutinib Promising for Treatment of Severe COVID-19

THURSDAY, June 11, 2020 (HealthDay News) — For patients with severe COVID-19, treatment with acalabrutinib, a selective bruton tyrosine kinase inhibitor, appears to improve oxygenation and reduce measures of inflammation, according to a study published in the June 5 issue of Science Immunology.

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Psychological Distress Up Among U.S. Adults During COVID-19 Pandemic

THURSDAY, June 11, 2020 (HealthDay News) — The prevalence of reported symptoms of psychological distress among U.S. adults was higher in 2020 during the COVID-19 pandemic than in 2018, according to a research letter published online June 3 in the Journal of the American Medical Association.

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VA May Not Have Enough PPE for Second COVID-19 Wave

WEDNESDAY, June 10, 2020 (HealthDay News) — The U.S. Department of Veterans Affairs says it may not have enough personal protective equipment for medical staff if there is a second wave of the COVID-19 pandemic.

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Study Will Assess Drugs Used to Treat Young COVID-19 Patients

WEDNESDAY, June 10, 2020 (HealthDay News) — A study to assess several drugs currently being used to treat COVID-19 in infants, children, and teens has been announced by the U.S. National Institute of Child Health and Human Development.

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Mild Symptoms ID’d in COVID-19 Outbreak on Aircraft Carrier

WEDNESDAY, June 10, 2020 (HealthDay News) — In a sample of young U.S. service members aboard an aircraft carrier, a COVID-19 outbreak was mainly characterized by widespread transmission with relatively mild symptoms and asymptomatic infection, according to research published in the June 9 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Obesity Linked to Greater Severity of Pediatric COVID-19

WEDNESDAY, June 10, 2020 (HealthDay News) — Obesity is the most common comorbidity among children and adolescents with COVID-19 and is associated with disease severity, according to a study published online June 3 in JAMA Pediatrics.

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Nine U.S. States Seeing Spikes in COVID-19 Hospitalizations

WEDNESDAY, June 10, 2020 (HealthDay News) — In another troubling sign that the spread of COVID-19 might be accelerating, new U.S. data show hospitalizations in at least nine states have been on the rise since Memorial Day.

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Troponin I Elevation Linked to Death in COVID-19 Patients

WEDNESDAY, June 10, 2020 (HealthDay News) — Among patients hospitalized with COVID-19, troponin I elevation is associated with an increased risk for death, according to a study published online June 8 in the Journal of the American College of Cardiology.

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Good Outcomes Seen in Hospitalized Pregnant Women With COVID-19

WEDNESDAY, June 10, 2020 (HealthDay News) — Most pregnant women admitted to U.K. hospitals with confirmed severe acute respiratory syndrome coronavirus 2 infection have good outcomes, according to a study published online June 8 in The BMJ.

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WHO Backpedals on Claim That Asymptomatic Transmission of New Coronavirus Is Rare

TUESDAY, June 9, 2020 (HealthDay News) — A claim that transmission of the COVID-19-causing coronavirus by people without symptoms is “very rare” was quickly reversed by the World Health Organization.

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Record-High Numbers of New COVID-19 Cases Seen in 14 States, Puerto Rico

TUESDAY, June 9, 2020 (HealthDay News) — A new analysis shows that parts of the country that had been spared the worst of the COVID-19 pandemic are now tallying record-high cases of new infections.

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Thromboelastography Can Predict Blood Clots in COVID-19

TUESDAY, June 9, 2020 (HealthDay News) — Hypercoagulable thromboelastography can predict thrombotic events in patients with COVID-19 in the intensive care unit, according to a research letter published online June 5 in JAMA Network Open.

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COVID-19 Mortality Rate for Intubated Adults Lower Than Previously Reported

TUESDAY, June 9, 2020 (HealthDay News) — Most patients with COVID-19 in the intensive care unit recover, with a mortality rate of 35.7 percent for those on mechanical ventilation, according to a study published online May 26 in Critical Care Medicine.

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Preoperative COVID-19 Incidence <1 Percent in Pediatric Patients

TUESDAY, June 9, 2020 (HealthDay News) — Among children undergoing preoperative screening, the overall incidence of COVID-19 is less than 1 percent, with considerable variation between regions, according to a research letter published online June 4 in JAMA Surgery.

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Partnership Would Bypass Drug Industry to Sell COVID-19 Vaccine

MONDAY, June 8, 2020 (HealthDay News) — A partnership that would bypass the drug industry to sell a potential vaccine against the new coronavirus has been formed by a laboratory at Imperial College London.

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WHO: People Should Wear Masks if Unable to Social Distance

MONDAY, June 8, 2020 (HealthDay News) — People who live in areas where the new coronavirus is spreading should wear fabric masks when they are shopping or on public transit and cannot social distance, the World Health Organization says in updated recommendations.

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Jail Cycling Is Significant Predictor of SARS-CoV-2 Infection

MONDAY, June 8, 2020 (HealthDay News) — Jail cycling is a significant predictor of severe acute respiratory syndrome coronavirus 2 infection, according to a report published online June 4 in Health Affairs.

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Kawasaki-Like Disease More Common in Children of African Ancestry

MONDAY, June 8, 2020 (HealthDay News) — A Kawasaki-like multisystem inflammatory syndrome, which is temporally associated with severe acute respiratory syndrome coronavirus 2 among children in Paris, seems more common among children of African ancestry, according to a study published online June 3 in The BMJ.

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Anesthesiologists Shift Practice From OR to ICU During Pandemic

MONDAY, June 8, 2020 (HealthDay News) — During the current new coronavirus pandemic, a large number of physician anesthesiologists pivoted from working in the operating room to treating COVID-19 patients in intensive care units, according to the results of an informal survey released by the American Society of Anesthesiologists.

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Attitude Toward Plastic Surgery Remains Positive During COVID-19

MONDAY, June 8, 2020 (HealthDay News) — Americans have a positive attitude toward plastic surgery in the COVID-19 period, and recommendations have been issued for resuming elective procedures, according to a press release issued by the American Society of Plastic Surgeons.

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Encounters for Suicidal Ideation in ED Down During ‘Stay at Home’

MONDAY, June 8, 2020 (HealthDay News) — Suicide ideation complaints to the emergency department decreased during the “stay at home” order for COVID-19, while the percentage of alcohol use presentations increased, according to a research letter published online June 1 in the American Journal of Emergency Medicine.

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