Findings based on data from three cohorts and updated meta-analysis of prospective cohort studies
THURSDAY, March 5, 2020 (HealthDay News) — Moderate egg consumption is not associated with the risk for cardiovascular disease overall, according to a study published online March 4 in The BMJ.
Jean-Philippe Drouin-Chartier, Ph.D., from the Harvard T. H. Chan School of Public Health in Boston, and colleagues examined the association between egg intake and cardiovascular disease risk among women and men in the United States in a prospective cohort study. Participants included 83,349 women from the Nurses’ Health Study (NHS), 90,214 women from NHS II, and 42,055 men from the Health Professionals’ Follow-Up Study.
The researchers identified 14,806 participants with incident cardiovascular disease in the three cohorts during up to 32 years of follow-up. In a pooled multivariable analysis, after adjustment for updated lifestyle and dietary factors associated with egg intake, consumption of at least one egg per day was not associated with incident cardiovascular disease risk (hazard ratio for at least one egg/day versus less than one egg/month, 0.93; 95 percent confidence interval, 0.82 to 1.05). In the updated meta-analysis of prospective cohort studies involving 1,720,108 participants with 139,195 cardiovascular disease events, there was no association noted for an increase of one egg per day with cardiovascular disease risk (pooled relative risk, 0.98; 95 percent confidence interval, 0.93 to 1.03).
“Recent studies reignited the debate on this controversial topic, but our study provides compelling evidence supporting the lack of an appreciable association between moderate egg consumption and cardiovascular disease,” Drouin-Chartier said in a statement.
Several authors disclosed financial ties to the nutrition industry.
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