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March 2020 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for March 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Case Fatality Ratio for COVID-19 Estimated at 1.38 Percent

TUESDAY, March 31, 2020 (HealthDay News) — The case fatality ratio for coronavirus disease 2019 (COVID-19) in China is estimated at 1.38 percent, according to a study published online March 30 in The Lancet Infectious Diseases.

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Preventionists Report Widespread Shortages of Protective Equipment

TUESDAY, March 31, 2020 (HealthDay News) — Nearly half of U.S. health care facilities surveyed are out of or almost out of respirators to use while caring for patients with COVID-19, according to the results of a national survey of infection prevention experts released March 27 by the Association for Professionals in Infection Control and Epidemiology (APIC).

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Doctors, Hospitals, Pharmacies Warned Not to Stockpile Meds

TUESDAY, March 31, 2020 (HealthDay News) — In a joint statement released by the American Medical Association, American Pharmacists Association, and American Society of Health-System Pharmacists, the professional groups “strongly oppose” physicians, pharmacies, and hospitals prophylactically prescribing medications or purchasing excessive amounts or stockpiles of potential treatments for COVID-19.

Joint Statement

Exclusive Breastfeeding for First Three Months May Cut Allergy Risk

TUESDAY, March 31, 2020 (HealthDay News) — Exclusive breastfeeding for the first three months of life may cut the risk for allergy and asthma later in childhood, according to a study published March 3 in Acta Paediatrica.

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Expressive Language Sampling Feasible in Fragile X Syndrome

MONDAY, March 30, 2020 (HealthDay News) — Expressive language sampling (ELS) procedures are feasible for most individuals with fragile X syndrome (FXS) aged 6 to 23 years with intellectual disability, according to a study published online March 24 in the Journal of Neurodevelopmental Disorders.

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Artificial Intelligence Framework May Predict ARDS in COVID-19

MONDAY, March 30, 2020 (HealthDay News) — Data from patients with coronavirus disease 2019 (COVID-19) can be used to develop a model that can predict who will develop acute respiratory distress syndrome (ARDS), according to a study published online March 30 in Computers, Materials & Continua.

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U.S. Army Opens Field Hospital in New York City

MONDAY, March 30, 2020 (HealthDay News) — The first U.S. Army field hospital for civilian patients opened in New York City Monday and could be the first of many across the nation as it struggles with the coronavirus pandemic.

CBS News Article

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Patients Viral Positive for Days After COVID-19 Resolution

MONDAY, March 30, 2020 (HealthDay News) — Some patients who have recovered from coronavirus disease 2019 (COVID-19) continue to be viral positive up to eight days after resolution of symptoms, according to a study published online March 23 in the American Journal of Respiratory and Critical Care Medicine.

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Proportion of Teens Receiving Mental Health Care Steady

MONDAY, March 30, 2020 (HealthDay News) — Nearly one in five U.S. adolescents receives care for mental health problems, a figure that has remained nearly constant from 2005 to 2018, according to a study published online March 25 in JAMA Psychiatry.

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ED Visit Provides Opportunity to Discuss Contraception With Teens

MONDAY, March 30, 2020 (HealthDay News) — Emergency departments provide an opportunity to offer contraceptive education to adolescent girls, according to a study recently published in the Journal of Women’s Health.

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Moderate Maternal Fish Intake May Aid Child Metabolic Health

FRIDAY, March 27, 2020 (HealthDay News) — Moderate fish intake during pregnancy (one to three times per week) is associated with improvements in the subsequent metabolic health of children, according to a study published online March 16 in JAMA Network Open.

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Pregnancy-Related Factors Linked to Risk for Psychosis in Child

FRIDAY, March 27, 2020 (HealthDay News) — Prenatal and perinatal factors may influence a child’s risk for developing psychosis, according to a review and meta-analysis published online March 24 in The Lancet Psychiatry.

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New Tool Measures Quality of Life With Autism Across Life Span

FRIDAY, March 27, 2020 (HealthDay News) — A new online survey appears to be a feasible and acceptable method for assessing patient- and parent-reported outcomes and quality of life for people with autism across the life span, according to a study published online March 10 in Autism Research.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 23 to 27, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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PPE Negative for SARS-CoV-2 After Patient Contact

FRIDAY, March 27, 2020 (HealthDay News) — Samples collected from personal protective equipment (PPE) from health care workers (HCWs) caring for patients positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were negative for SARS-CoV-2, according to research published online March 26 in Infection Control & Hospital Epidemiology.

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Three Neonates Born to Mothers With COVID-19 ID’d as Positive

FRIDAY, March 27, 2020 (HealthDay News) — Three of 33 neonates born to mothers with coronavirus disease 2019 (COVID-19) in Wuhan tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) , according to a research letter published online March 26 in JAMA Pediatrics.

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Elastomeric Half-Mask Respirator Training Feasible in Health Care

FRIDAY, March 27, 2020 (HealthDay News) — Health care personnel can be rapidly fit tested and trained to use the reusable elastomeric half-mask respirator (EHMR), with similar time to testing as that seen for the N95 respirator, according to a research letter published online March 25 in the Journal of the American Medical Association.

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BP Load No Aid to Prognosis in Pediatric Chronic Kidney Disease

FRIDAY, March 27, 2020 (HealthDay News) — Blood pressure (BP) load does not provide additive value in predicting outcomes in children with chronic kidney disease (CKD), according to a study published online March 11 in the Clinical Journal of the American Society of Nephrology.

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Prevalence of Autism Spectrum Disorder 18.5 per 1,000 at Age 8

THURSDAY, March 26, 2020 (HealthDay News) — The prevalence of autism spectrum disorder (ASD) was 18.5 per 1,000 among children aged 8 years and 15.6 per 1,000 children aged 4 years in 2016, according to two surveillance summaries published in the March 27 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Restricting Activities in Wuhan Until April Could Slow COVID-19 Peak

THURSDAY, March 26, 2020 (HealthDay News) — Restriction on activities in Wuhan would help to delay the COVID-19 epidemic peak if maintained until April, according to a study published online March 25 in The Lancet Public Health.

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Workers at Risk for COVID-19 Exposure Can Access Online Training

THURSDAY, March 26, 2020 (HealthDay News) — The National Institutes of Health has launched a new website with educational resources for hospital employees, emergency first responders, and other workers at risk for exposure to COVID-19.

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Prospective, Randomized Studies of AI Lacking in Medical Imaging

THURSDAY, March 26, 2020 (HealthDay News) — In the field of medical imaging, there are few prospective studies and randomized trials of deep learning, according to a review published online March 25 in The BMJ.

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CDC: Rates of STIs Up From 2016 to 2018 Among Women Giving Birth

THURSDAY, March 26, 2020 (HealthDay News) — From 2016 to 2018, the rates of three sexually transmitted infections (STIs) increased among women giving birth, according to the March 26 National Vital Statistics Reports, a publication from the U.S. Centers for Disease Control and Prevention.

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FDA Warns of Defective EpiPen Dangers

WEDNESDAY, March 25, 2020 (HealthDay News) — Certain types of EpiPens and their generic counterparts may fail or delay injection of lifesaving epinephrine for severe allergic reactions, the U.S. Food and Drug Administration warns.

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National Health Spending Expected to Increase Through 2028

WEDNESDAY, March 25, 2020 (HealthDay News) — National health expenditures are projected to increase at an average annual rate of 5.4 percent for 2019 to 2028, representing almost 20 percent of U.S. gross domestic product by 2028, according to a study published online March 24 in Health Affairs.

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Proton Pump Inhibitors May Up Fracture Risk in Children

WEDNESDAY, March 25, 2020 (HealthDay News) — Proton pump inhibitor (PPI) use in children is associated with a small but significant increased risk for any fracture, according to a study published online March 16 in JAMA Pediatrics.

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Many Children in the United States Still Have Poor Diets

TUESDAY, March 24, 2020 (HealthDay News) — More than half of U.S. youth have poor diets, according to a study published in the March 24/31 issue of the Journal of the American Medical Association.

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Recommendations Issued for Pediatric Abuse-Related Head Trauma

TUESDAY, March 24, 2020 (HealthDay News) — In an American Academy of Pediatrics policy statement, published online March 23 in Pediatrics, recommendations are presented for pediatricians to manage abusive head trauma (AHT) in infants and children.

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IDSA Issues Recommendations for COVID-19 Testing

TUESDAY, March 24, 2020 (HealthDay News) — In a statement published online March 19 by the Infectious Diseases Society of America (IDSA), recommendations are presented for public health and health care professionals to prioritize coronavirus disease 2019 (COVID-19) testing.

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Early Age at Puberty Linked to Increased T2DM Risk in Men

TUESDAY, March 24, 2020 (HealthDay News) — For men, early age at puberty is associated with an increased risk for type 2 diabetes, according to a study published online March 23 in Diabetologia.

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Information on COVID-19 Provided for Gastroenterologists

TUESDAY, March 24, 2020 (HealthDay News) — In a special article published online March 17 in Clinical Gastroenterology and Hepatology, key information is presented about coronavirus disease 2019 (COVID-19) and the field of gastroenterology.

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No Evidence Found for SARS-CoV-2 Vertical Transmission to Fetus

TUESDAY, March 24, 2020 (HealthDay News) — There is currently no evidence that SARS-CoV-2 undergoes intrauterine or transplacental transmission from coronavirus disease 2019 (COVID-19)-infected pregnant women to fetuses, according to a study published online March 17 in the Archives of Pathology & Laboratory Medicine.

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Article Addresses Management of Cancer Care During COVID-19

MONDAY, March 23, 2020 (HealthDay News) — Management of cancer care during the coronavirus 2019 (COVID-19) pandemic is addressed in a special feature article published online March 20 in the Journal of the National Comprehensive Cancer Network.

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CDC: Modest Decreases Seen in TB Cases, TB-Related Deaths

MONDAY, March 23, 2020 (HealthDay News) — From 2017 to 2018, there were modest decreases in the number of persons with tuberculosis (TB) and the number of TB-related deaths, according to research published in the March 20 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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E. Coli Outbreak Tied to Clover Sprouts Rises to 39 Cases in Six States

FRIDAY, March 20, 2020 (HealthDay News) — The number of cases in an Escherichia coli outbreak linked to clover sprouts has reached 39 in six states, the U.S. Centers for Disease Control and Prevention said Thursday.

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Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician’s Briefing chose as the most important COVID-19 developments for you and your practice for the week of March 16 to 20, 2020. This roundup includes the latest research news from journal studies and other trusted sources that is most likely to affect clinical practice.

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Incidence of Tuberculosis High in Children Exposed to the Disease

FRIDAY, March 20, 2020 (HealthDay News) — The incidence of developing tuberculosis is high among exposed infants and young children, according to a review published in the March 21 issue of The Lancet.

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2nd Trimester Antibiotic Exposure May Up Risk for Offspring Obesity

FRIDAY, March 20, 2020 (HealthDay News) — Prenatal antibiotic exposure overall has no significant association with later overweight or obesity in children, but exposure during the second trimester may up later risk, according to a review published online March 3 in Obesity.

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Serial Interval of COVID-19 Estimated at 3.96 Days

FRIDAY, March 20, 2020 (HealthDay News) — The serial interval of coronavirus 2019 (COVID-19), defined as the time between a primary case and secondary case developing symptoms, is 3.96 days, according to a study published online March 19 in Emerging Infectious Diseases, a publication of the U.S. Centers for Disease Control and Prevention.

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Sports Concussion Recovery May Be Slower Than Thought

THURSDAY, March 19, 2020 (HealthDay News) — Less than half of patients with sports-related mild traumatic brain injury (SR-mTBI) achieve clinical recovery within two weeks after injury, according to a study published in the March issue of the Clinical Journal of Sport Medicine.

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Antibiotics in First Year of Life May Up Risk for T1DM by Age 10

THURSDAY, March 19, 2020 (HealthDay News) — Antibiotic prescriptions in the first year of life are associated with an increased risk for type 1 diabetes in childhood, according to a study published online March 4 in Diabetes Care.

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Most Mass Shooting Events Occur Close to Nontrauma Centers

WEDNESDAY, March 18, 2020 (HealthDay News) — In 2019, there were 187 mass shooting events, most of which occurred closest to a nontrauma center, according to a research letter published online March 18 in JAMA Surgery.

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Teens Who Try E-Cigs First Less Likely to Smoke Cigarettes

WEDNESDAY, March 18, 2020 (HealthDay News) — U.S. adolescents who first use electronic cigarettes (e-cigarettes) are less likely to be subsequent smokers, according to a study published online March 17 in Tobacco Control.

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Demographics May Predict Choice to Not Vaccinate Children

WEDNESDAY, March 18, 2020 (HealthDay News) — Texans who are college-educated, live in suburban or urban areas, have higher median incomes, and are ethnically white are less likely to vaccinate their children, according to a study published online March 10 in PLOS Medicine.

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Metformin Could Reduce Obesity in Children

WEDNESDAY, March 18, 2020 (HealthDay News) — Metformin treatment reduces some obesity measures in children, according to a review and meta-analysis published online Feb. 18 in Childhood Obesity.

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Graphic Health Warnings Coming for U.S. Cigarette Packs

TUESDAY, March 17, 2020 (HealthDay News) — Graphic new health warnings must appear on cigarette packages and in cigarette ads beginning next year, the U.S. Food and Drug Administration says.

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Per-Capita Medical Radiation Exposure Down in United States

TUESDAY, March 17, 2020 (HealthDay News) — From 2006 to 2016, there was a decrease in per-capita exposure to medical radiation in the United States, according to a study published online March 17 in Radiology.

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Children Susceptible to COVID-19 but Less Severely Affected

TUESDAY, March 17, 2020 (HealthDay News) — Children of all ages seem to be susceptible to novel coronavirus 2019 (COVID-19) infection, and most cases are asymptomatic, mild, or moderate, according to a study published online March 16 in Pediatrics.

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Young Adults Using Juul More Than Non-Pod-Based E-Cigarettes

TUESDAY, March 17, 2020 (HealthDay News) — Young adults report ever use of Juul more often than smoking cigarettes and using non-pod-based electronic cigarettes (e-cigarettes), according to a study published online March 16 in the Journal of Adolescent Health.

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Climate Similar in Cities With Biggest Outbreaks of COVID-19

TUESDAY, March 17, 2020 (HealthDay News) — Cities that have experienced significant outbreaks of coronavirus 2019 (COVID-19) have similar winter climates, according to a study published online March 9 on the open-data site SSRN.

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Low Maternal Vitamin D May Raise Risk for ADHD in Offspring

MONDAY, March 16, 2020 (HealthDay News) — There is an association between low maternal vitamin D during early pregnancy and an elevated risk for offspring attention-deficit/hyperactivity disorder (ADHD), according to a study recently published in the Journal of the American Academy of Child & Adolescent Psychiatry.

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Antibiotics May Not Help Children With Suspected Pneumonia

MONDAY, March 16, 2020 (HealthDay News) — For children with suspected community-acquired pneumonia (CAP) who are discharged from the emergency department, outcomes do not differ between those who do and those who do not receive antibiotic prescriptions, according to a study published online March 16 in Pediatrics.

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Poll: Many Parents Not Talking to Children About Inappropriate Touching

MONDAY, March 16, 2020 (HealthDay News) — Many parents are not having talks with their preschool or school-age children about inappropriate touching, according to a new C.S. Mott Children’s Hospital national poll from the University of Michigan in Ann Arbor.

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Case Series Indicates COVID-19 Not Transmitted In Utero

MONDAY, March 16, 2020 (HealthDay News) — Four infants born to pregnant women who tested positive for coronavirus 2019 (COVID-19) were healthy at birth and had no serious clinical symptoms, according to a case series study published online March 16 in Frontiers in Pediatrics.

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Evidence Shows Co-Occurrence, Coaggregation of Asthma, T1DM

FRIDAY, March 13, 2020 (HealthDay News) — There is evidence for co-occurrence and coaggregation of asthma and type 1 diabetes in children and their siblings, according to a study published online March 13 in JAMA Network Open.

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>8 Percent of Children Report Past, Current Suicidal Ideation

FRIDAY, March 13, 2020 (HealthDay News) — About 8 percent of children report any past or current suicidal ideation, according to a study published online March 12 in The Lancet Psychiatry.

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Enoki Mushrooms From Korea Linked to Deadly U.S. Listeria Outbreak

THURSDAY, March 12, 2020 (HealthDay News) — Enoki mushrooms from Korea are the likely cause of a deadly Listeria outbreak in the United States that has sickened 36 people in 17 states, the U.S. Centers for Disease Control and Prevention says.

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Decreases Seen in Cancer Incidence, Death Rates

THURSDAY, March 12, 2020 (HealthDay News) — Cancer incidence and death rates have decreased in recent years, according to two studies published online March 12 in Cancer.

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Acute Appendicitis Incidence Not Randomly Distributed

TUESDAY, March 10, 2020 (HealthDay News) — Socioeconomic status and other geographically defined factors are associated with incidence of acute appendicitis (AA), according to a study published online March 4 in JAMA Surgery.

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Atopic Comorbidity Up in Children With Food Protein-Induced Enterocolitis

WEDNESDAY, March 11, 2020 (HealthDay News) — Children with food protein-induced enterocolitis syndrome (FPIES) have higher rates of atopic comorbidity, according to a study published online in the March issue of the Journal of Allergy and Clinical Immunology: In Practice.

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Daily Rounding Helps Curb CAUTIs in Pediatric ICU Patients

WEDNESDAY, March 11, 2020 (HealthDay News) — Targeted rounding for pediatric patients with an indwelling urinary catheter is an effective and sustainable strategy to reduce catheter-associated urinary tract infections (CAUTIs), according to a study recently published in Critical Care Nurse.

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Leanness, Tallness in School-Aged Girls Linked to Risk for Endometriosis

TUESDAY, March 10, 2020 (HealthDay News) — For girls, leanness and tallness during school age are associated with increased risks for endometriosis, but not adenomyosis, according to a study published online March 9 in the Annals of Human Biology.

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Infant Sleep Problems Affect Mental Health Through Childhood

TUESDAY, March 10, 2020 (HealthDay News) — Persistent severe sleep problems during the first postnatal year are associated with an increased risk for anxiety problems and emotional disorders at age 10, according to a study published online March 9 in the Archives of Disease in Childhood.

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2018 Health Care Spending Up Due to Higher Prices

MONDAY, March 9, 2020 (HealthDay News) — Average employer-sponsored insurance spending rose to $5,892 per person in 2018, according to the Health Care Cost Institute annual Health Care Cost and Utilization Report.

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Rotavirus Vaccination, Type 1 Diabetes Not Linked in Children

MONDAY, March 9, 2020 (HealthDay News) — Rotavirus vaccination seems not to be associated with type 1 diabetes in children, according to a study published online March 9 in JAMA Pediatrics.

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FDA: Cybersecurity Vulnerabilities May Affect Medical Devices

FRIDAY, March 6, 2020 (HealthDay News) — SweynTooth cybersecurity vulnerabilities may affect medical devices, according to a U.S. Food and Drug Administration safety communication.

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FDA: Singulair to Get ‘Black Box’ Warning

THURSDAY, March 5, 2020 (HealthDay News) — Asthma and allergy drug montelukast — sold as a generic and under the brand name Singulair — will get a “boxed warning” over potential ties to neuropsychiatric effects, the U.S. Food and Drug Administration announced Wednesday.

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Less Than 1 in 4 Perinatally Exposed Infants Tested for Hep C

THURSDAY, March 5, 2020 (HealthDay News) — Less than one-quarter of infants exposed to hepatitis C virus (HCV) receive testing, according to a study published in the March issue of Pediatrics.

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Female Clinical Chairs Paid Significantly Less Than Men

THURSDAY, March 5, 2020 (HealthDay News) — There are significant sex differences in salaries of clinical department chairs in public medical schools in the United States, according to a research letter published online March 2 in JAMA Internal Medicine.

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CDC: ~14 Percent of Children Have ADHD, Learning Disability

WEDNESDAY, March 4, 2020 (HealthDay News) — Nearly 14 percent of children aged 3 to 17 years had ever been diagnosed with attention-deficit/hyperactivity disorder (ADHD) or a learning disability in 2016 to 2018, according to a March data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Late Mortality Down for Young Adult, Adolescent Cancer Survivors

WEDNESDAY, March 4, 2020 (HealthDay News) — All-cause and cause-specific mortality have decreased among five-year adolescent and young adult (AYA) cancer survivors overall, but improvements have not been consistent across all cancer types, according to a study published online March 3 in the Journal of the National Cancer Institute.

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Racial/Ethnic Insurance Coverage Disparity Down Since ACA

WEDNESDAY, March 4, 2020 (HealthDay News) — Since the implementation of coverage expansions associated with the Affordable Care Act (ACA), the disparities in insurance coverage related to race and ethnicity have decreased, according to a study published in the March issue of Health Affairs.

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Considerable Increase Seen in List, Net Prices of Branded Drugs

WEDNESDAY, March 4, 2020 (HealthDay News) — From 2007 to 2018, there were substantial increases in list and net prices of branded drugs in the United States, according to a study published in the March 3 issue of the Journal of the American Medical Association.

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Shift in Birth Timing Tied to Decline in Birth Weights

WEDNESDAY, March 4, 2020 (HealthDay News) — If rates of obstetric practices had not changed between 1990 and 2013 to include more cesarean deliveries and inductions, then the average U.S. birth weight likely would have increased over this time, according to research published online Jan. 29 in Demography.

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1996 to 2016 Saw Increases in U.S. Spending on Health Care

TUESDAY, March 3, 2020 (HealthDay News) — From 1996 to 2016, there were considerable increases in U.S. spending on health care, according to a study published in the March 3 issue of the Journal of the American Medical Association.

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NICU Babies at Risk for Later Mental Health Issues

TUESDAY, March 3, 2020 (HealthDay News) — Survivors of the neonatal intensive care unit (NICU) are at an increased risk for psychiatric disorders during childhood and adolescence, according to a study recently published in Archives of Disease in Childhood.

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Mean Age at Drug Use Initiation Increasing for Many Drugs

MONDAY, March 2, 2020 (HealthDay News) — For many internationally regulated drugs, the mean age at initiation has increased since 2004, according to a research letter published online March 2 in JAMA Pediatrics.

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Pediatrician Use of Developmental Screening Tools Increasing

MONDAY, March 2, 2020 (HealthDay News) — From 2002 to 2016, there was an increase in pediatricians’ reported use of developmental screening tools and in referral of at-risk patients for early intervention (EI), according to a study published online March 2 in Pediatrics.

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