Home News General Health News June 2019 Briefing – Pharmacy

June 2019 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for June 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Five-Year Survival Less Than 40 Percent in Seniors With DLBCL

FRIDAY, June 28, 2019 (HealthDay News) — Overall survival among older adults with diffuse large B-cell lymphoma (DLBCL) has improved over time, but five-year survival is less than 40 percent, according to a study published online June 12 in Leukemia & Lymphoma.

Abstract/Full Text

Soliris Approved to Treat Neuromyelitis Optica Spectrum Disorder

FRIDAY, June 28, 2019 (HealthDay News) — The U.S. Food and Drug Administration has approved Soliris (eculizumab) injection as the first treatment for neuromyelitis optica spectrum disorder (NMOSD), the agency announced Thursday.

More Information

ACIP: Men as Old as 26 Should Get HPV Vaccine

THURSDAY, June 27, 2019 (HealthDay News) — The recommended maximum age for male HPV vaccination should be raised from 21 to 26 years, a U.S. government advisory group said.

AP News Article – HPV

AP News Article – Prevnar 13

Similar CV Event Rates Seen for Generic, Brand Levothyroxine

THURSDAY, June 27, 2019 (HealthDay News) — Cardiovascular event rates are similar for patients with newly treated hypothyroidism receiving generic and brand levothyroxine (L-T4), according to a study published online April 26 in the Mayo Clinic Proceedings.

Abstract/Full Text

Psoriasis Patients Often Use CAMs When Traditional Meds Fail

THURSDAY, June 27, 2019 (HealthDay News) — Patients with psoriasis frequently use complementary and alternative medicines (CAMs) because traditional medications failed or caused side effects, according to a research letter published in the July issue of the Journal of the American Academy of Dermatology.

Abstract/Full Text (subscription or payment may be required)

Dupixent Approved for Chronic Rhinosinusitis With Nasal Polyps

WEDNESDAY, June 26, 2019 (HealthDay News) — Dupixent (dupilumab) has been approved to treat nasal polyps in adults with chronic rhinosinusitis, the U.S. Food and Drug Administration announced today.

More Information

Combination Therapy for Rosacea Shows Improved Response Rates

WEDNESDAY, June 26, 2019 (HealthDay News) — Combining ivermectin cream (IVM) and doxycycline modified-release capsules (DMR) can improve response rates for patients with severe rosacea, according to a study recently published in the Journal of the American Academy of Dermatology.

Abstract/Full Text

MSSP ACOs May Not Improve Spending, Quality of Care

WEDNESDAY, June 26, 2019 (HealthDay News) — After adjustment for the nonrandom exit of clinicians, the Medicare Shared Savings Program (MSSP) is not associated with improvements in spending or quality, according to a study published online June 18 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Americans Concerned About Clinician Burnout

WEDNESDAY, June 26, 2019 (HealthDay News) — Nearly three-quarters of Americans are concerned about burnout among their clinicians, according to a survey released June 17 by the American Society of Health-System Pharmacists (ASHP).

More Information

Nutrient Intake Inadequate in Many Pregnant Women in U.S.

TUESDAY, June 25, 2019 (HealthDay News) — Even with dietary supplements, a substantial number of pregnant women in the United States are not meeting recommendations for vitamins D, C, A, B6, K, and E as well as folate, choline, iron, calcium, potassium, magnesium, and zinc, according to a study published online June 21 in JAMA Network Open.

Abstract/Full Text

FDA Warns Two Kratom Marketers About False Claims

TUESDAY, June 25, 2019 (HealthDay News) — The U.S. Food and Drug Administration on Tuesday took two kratom marketers to task over false claims that their products can treat or cure opioid addiction.

More Information

Exposure to Anticholinergics May Increase Dementia Risk

TUESDAY, June 25, 2019 (HealthDay News) — Exposure to anticholinergic drugs is associated with an increased dementia risk, according to a study published online June 24 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Anesthesia Tied to Neurocognitive Impairment in Childhood ALL Survivors

TUESDAY, June 25, 2019 (HealthDay News) — Multiple exposures to general anesthesia may be associated with neurocognitive impairment and brain imaging abnormalities in long-term survivors of childhood acute lymphoblastic leukemia (ALL), according to a study published online June 20 in JAMA Oncology.

Abstract/Full Text (subscription or payment may be required)

Voxelotor Improves Hemoglobin Levels in Sickle Cell Disease

TUESDAY, June 25, 2019 (HealthDay News) — For individuals with sickle cell disease, 1,500 mg of voxelotor increases hemoglobin levels and reduces the incidence of worsening anemia compared with placebo, according to a study published in the June 14 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Iron Intake May Not Improve Pregnancy Chances

TUESDAY, June 25, 2019 (HealthDay News) — There is little association between iron intake and chances of conception overall, according to a study published online June 1 in the Journal of Nutrition.

Abstract/Full Text (subscription or payment may be required)

Colonoscopy Quality Not Affected by Sedation Method

MONDAY, June 24, 2019 (HealthDay News) — Among patients at average risk undergoing screening colonoscopies, there is no benefit associated with deep sedation versus moderate sedation, according to a study recently published in Gastrointestinal Endoscopy.

Abstract/Full Text (subscription or payment may be required)

Many Trust Doctors, Nurses Over Other Sources of Health Advice

MONDAY, June 24, 2019 (HealthDay News) — Globally, about three-quarters of people trust doctors or nurses more than other sources when it comes to health advice, according to a report published online June 19 by the Wellcome Global Monitor.

More Information

Vyleesi Approved for Hypoactive Sexual Desire Disorder in Women

MONDAY, June 24, 2019 (HealthDay News) — Vyleesi (bremelanotide) has been approved to treat acquired, generalized hypoactive sexual desire disorder in premenopausal women, the U.S. Food and Drug Administration announced Friday.

More Information

Antacid Use in First Year of Life Tied to Later Fracture Risk

MONDAY, June 24, 2019 (HealthDay News) — Infants who are given acid suppression therapy (AST) in their first year of life are more likely to subsequently break a bone, according to a study published online June 7 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Drug Combo Slows Progression in Advanced Breast Cancer

MONDAY, June 24, 2019 (HealthDay News) — Treatment with a combination of alpelisib and fulvestrant prolongs progression-free survival among patients with PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer, according to a phase 3 study recently published in the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Rotavirus Vaccine Led to Reduced Disease Prevalence, Season Duration

MONDAY, June 24, 2019 (HealthDay News) — Implementation of rotavirus vaccination has reduced disease prevalence and season duration in the United States, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Oral Steroids Increase Infection Risk in Inflammatory Disease

MONDAY, June 24, 2019 (HealthDay News) — The incidence of infection increases with glucocorticoid dose for patients with polymyalgia rheumatica or giant cell arteritis, according to a study published online June 24 in CMAJ, the journal of the Canadian Medical Association.

Abstract/Full Text (subscription or payment may be required)

FDA Expands Cystic Fibrosis Treatment Approval to Children Ages 6 to 12

FRIDAY, June 21, 2019 (HealthDay News) — The indication for a cystic fibrosis treatment, Symdeko (tezacaftor/ivacaftor) tablets, has been expanded to treat children ages 6 years and older with cystic fibrosis and certain genetic mutations, the U.S. Food and Drug Administration announced today.

More Information

2018 Saw Increase in Cosmetic Procedures for Over 55s

FRIDAY, June 21, 2019 (HealthDay News) — More Americans age 55 years and older are undergoing cosmetic procedures, with a 2 percent increase in total cosmetic procedures from 2017 to 2018, according to a report from the American Society of Plastic Surgeons.

More Information

Incident A-Fib Linked to Increased Dementia Risk

FRIDAY, June 21, 2019 (HealthDay News) — Incident atrial fibrillation (AF) is associated with increased dementia risk in elderly populations, according to a study published online June 18 in the European Heart Journal.

Abstract/Full Text

New England Journal of Medicine Picks New Editor-in-Chief

THURSDAY, June 20, 2019 (HealthDay News) — The new editor-in-chief of the prestigious New England Journal of Medicine is Eric J. Rubin, M.D., Ph.D., who was selected after a worldwide search and plans to start in September, according to the Massachusetts Medical Society, which publishes the journal.

More Information

2018 to 2019 Influenza Season in U.S. Was Longest in 10 Years

THURSDAY, June 20, 2019 (HealthDay News) — In the United States, the 2018 to 2019 influenza season was of moderate severity and lasted 21 weeks, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Meta-Analysis Does Not Link Vitamin D Supplements, Drop in MACE

THURSDAY, June 20, 2019 (HealthDay News) — Vitamin D supplementation is not associated with a reduced risk for major adverse cardiovascular events, according to a meta-analysis published online June 19 in JAMA Cardiology.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Health Care Workers With ARIs Often Work While Symptomatic

THURSDAY, June 20, 2019 (HealthDay News) — Almost all health care workers (HCWs) with acute respiratory illness (ARI) report working at least one day while symptomatic, according to a study published online June 18 in Infection Control & Hospital Epidemiology.

Abstract/Full Text

High Response Seen for Chemo in Seniors With High-Risk AML

THURSDAY, June 20, 2019 (HealthDay News) — A substantial proportion of older patients with high-risk acute myeloid leukemia (AML) treated with chemotherapy are long-term survivors, according to research published online June 7 in Cancer Medicine.

Abstract/Full Text

Elderly Women May Still Benefit From Osteoporosis Treatment

THURSDAY, June 20, 2019 (HealthDay News) — Late-life women with osteoporosis, including those with comorbidities, may still be drug treatment candidates to prevent future hip fracture, according to a study published online June 17 in JAMA Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Sudden Death Can Occur in Full Spectrum of Epilepsies

WEDNESDAY, June 19, 2019 (HealthDay News) — Sudden unexpected death in epilepsy (SUDEP) can occur across the full spectrum of epilepsies, according to a study published online June 19 in Neurology.

Abstract/Full Text (subscription or payment may be required)

Cardiovascular AEs Common With Carfilzomib in Multiple Myeloma

WEDNESDAY, June 19, 2019 (HealthDay News) — For patients with relapsed multiple myeloma (MM), cardiovascular adverse events (CVAEs) are common with proteasome inhibitor therapy, particularly with carfilzomib, and are associated with inferior survival, according to a study published online June 12 in the Journal of Clinical Oncology.

Abstract/Full Text (subscription or payment may be required)

Statins May Be Beneficial After Radiation to Thorax, Head, Neck

WEDNESDAY, June 19, 2019 (HealthDay News) — For cardiac patients with thorax and head or neck cancer, statin use after radiation therapy is associated with a significant reduction in stroke incidence and a trend toward reduced cardiovascular and cerebrovascular events, according to a study published online June 19 in the Journal of the American Heart Association.

Abstract/Full Text

Patterns of Inpatient Opioid Use Linked to Long-Term Use

TUESDAY, June 18, 2019 (HealthDay News) — Specific patterns of opioid administration to opioid-naive inpatients are associated with risk for long-term use after discharge, according to a study published online June 18 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Pediatric T1DM Medication Adherence Drops on Weekends, Holidays

TUESDAY, June 18, 2019 (HealthDay News) — For children with type 1 diabetes, medication adherence is lower during school holidays and on weekends, according to a study recently published in the Archives of Disease in Childhood.

Abstract/Full Text (subscription or payment may be required)

Adding Bevacizumab Improves Overall Survival in NSCLC

TUESDAY, June 18, 2019 (HealthDay News) — The addition of bevacizumab to carboplatin/pemetrexed is associated with improved overall survival among patients with advanced non-small cell lung cancer (NSCLC), according to a study published in the May issue of the Journal of the National Comprehensive Cancer Network.

Abstract/Full Text

FDA Approves Victoza Injection for Children 10 Years and Older

TUESDAY, June 18, 2019 (HealthDay News) — Victoza (liraglutide) injection is now approved to treat type 2 diabetes in children 10 years and older, the U.S. Food and Drug Administration announced yesterday.

More Information

Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads

MONDAY, June 17, 2019 (HealthDay News) — Three large drug makers have launched a legal challenge against the Trump administration’s rule requiring the prices of drugs to be included in television ads.

The New York Times Article

WHO: Congo Ebola Outbreak Still Not Global Emergency

MONDAY, June 17, 2019 (HealthDay News) — Even though the Ebola outbreak in Congo recently caused deaths in neighboring Uganda, it is still not a global emergency, the World Health Organization says.

AP News Article

Nilvadipine Increases Cerebral Blood Flow in the Hippocampus

MONDAY, June 17, 2019 (HealthDay News) — For patients with mild-to-moderate Alzheimer disease, treatment with nilvadipine lowers systolic blood pressure and increases cerebral blood flow (CBF) in the hippocampus, according to a study published online June 17 in Hypertension.

Abstract/Full Text (subscription or payment may be required)

Recommendations Developed to Prepare Children for Camp

MONDAY, June 17, 2019 (HealthDay News) — In a policy statement issued by the American Academy of Pediatrics and published online June 17 in Pediatrics, recommendations are presented for the preparation of children for summer camps.

Abstract/Full Text

PPI Use for Up to Three Years Safe During Anticoagulant Tx

MONDAY, June 17, 2019 (HealthDay News) — Use of pantoprazole for up to three years to prevent upper gastrointestinal events in patients receiving anticoagulant therapy with aspirin and/or rivaroxaban has a similar safety profile to placebo except for an increased risk for enteric infections, according to a study published online May 29 in Gastroenterology.

Abstract/Full Text (subscription or payment may be required)

U.S. Travelers Should Be Aware of Measles Risk in Europe

MONDAY, June 17, 2019 (HealthDay News) — U.S. travelers need to be aware of measles in Europe and should ensure children are adequately vaccinated, according to a study published online June 17 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)

New York State Halts Religious Vaccine Exemption

FRIDAY, June 14, 2019 (HealthDay News) — Reacting to an ongoing measles outbreak, New York state has eliminated the religious exemption for not vaccinating children.

AP News Article

Rotavirus Vaccination Tied to Lower Risk for T1DM in Children

FRIDAY, June 14, 2019 (HealthDay News) — Completion of full rotavirus vaccination appears to be associated with a reduction in the risk of type 1 diabetes in children, according to a study published online June 13 in Scientific Reports.

Abstract/Full Text

Prenatal Antiepileptic Rx Exposure Ups Risk for Behavioral Issues

FRIDAY, June 14, 2019 (HealthDay News) — There is an increased risk for behavioral problems in children of mothers with epilepsy who take common antiepileptic drugs during pregnancy, according to a study published online June 5 in Epilepsia.

Abstract/Full Text

Infliximab Introduction Has Not Cut IBD-Related Hospitalizations

FRIDAY, June 14, 2019 (HealthDay News) — Marketplace introduction of infliximab has not resulted in reductions in the population rates of inflammatory bowel disease (IBD)-related hospitalizations or intestinal resections or colectomies, according to a study published online June 13 in Gut.

Abstract/Full Text (subscription or payment may be required)

Opioid-Sparing Strategy Still Provides Good Pain Control

FRIDAY, June 14, 2019 (HealthDay News) — Following implementation of an opioid-sparing pain management strategy, half of patients report using no opioids and adequate pain control, according to a study published online May 30 in the Journal of the American College of Surgeons.

Abstract/Full Text (subscription or payment may be required)

More Aggressive Statin Tx Needed After Heart Attack in Young Patients

FRIDAY, June 14, 2019 (HealthDay News) — The majority of young heart attack patients with familial hypercholesterolemia (FH) still have elevated cholesterol levels a year later, according to a study published in the May 21 issue of the Journal of the American College of Cardiology.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

CDC Opens Emergency Operations Center for Congo Ebola Outbreak

THURSDAY, June 13, 2019 (HealthDay News) — The United States is stepping up its response to a historic outbreak of Ebola in two African nations. The U.S. Centers for Disease Control and Prevention activated its Emergency Operations Center Thursday to assist in the government’s response to the second-largest outbreak of Ebola on record.

More Information

Drug, Alcohol, and Suicide Deaths Up Among Millennials

THURSDAY, June 13, 2019 (HealthDay News) — Drug, alcohol, and suicide deaths have increased among millennials, according to a report issued by the Trust for America’s Health and the Well Being Trust.

More Information

HIV Risk Does Not Differ With Three Contraceptive Methods

THURSDAY, June 13, 2019 (HealthDay News) — For African women seeking effective contraception, there is no significant difference in HIV incidence with use of intramuscular depot medroxyprogesterone acetate (DMPA-IM), a copper intrauterine device (IUD), and a levonorgestrel (LNG) implant, according to a study published online June 13 in The Lancet.

Abstract/Full Text

Gabapentinoids Linked to Increased Risk for Significant Adverse Outcomes

THURSDAY, June 13, 2019 (HealthDay News) — Gabapentinoids are associated with increased risks for adverse outcomes related to coordination disturbances, mental health, and criminality, according to a study published online June 12 in The BMJ.

Abstract/Full Text

Editorial

Long-Term Opioid Prescribing Up Among Older Cancer Survivors

THURSDAY, June 13, 2019 (HealthDay News) — The rates of prolonged opioid prescribing remain high for older cancer survivors five or more years after cancer diagnosis, according to a study published in the May issue of the Journal of the American Geriatrics Society.

Abstract/Full Text (subscription or payment may be required)

Chemoradiation Does Not Up Survival in Endometrial Cancer

WEDNESDAY, June 12, 2019 (HealthDay News) — For patients with stage III or IVA endometrial cancer, chemotherapy plus radiation is not associated with improved relapse-free survival versus chemotherapy alone, according to a study published in the June 13 issue of the New England Journal of Medicine.

Abstract/Full Text (subscription or payment may be required)

Study Confirms Teratogenicity of Valproic Acid, Topiramate

WEDNESDAY, June 12, 2019 (HealthDay News) — Valproic acid and topiramate are confirmed teratogens, according to a study published online June 12 in Neurology.

Abstract/Full Text (subscription or payment may be required)

CDC: Wildlife Rabies, Especially in Bats, Poses Risk in U.S.

WEDNESDAY, June 12, 2019 (HealthDay News) — Wildlife rabies, especially in bats, poses a risk to humans in the United States, and postexposure prophylaxis (PEP) is important for preventing death, according to research published in the June 12 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

Abstract/Full Text

Approving Children’s Cancer Drugs Takes 6.5 Years Longer

WEDNESDAY, June 12, 2019 (HealthDay News) — For cancer drugs ultimately approved by the U.S. Food and Drug Administration, the median lag time from first-in-human to first-in-child trials is 6.5 years, according to a study published in the May issue of the European Journal of Cancer.

Abstract/Full Text (subscription or payment may be required)

Weight Loss Surgery May Not Relieve Acid Reflux

WEDNESDAY, June 12, 2019 (HealthDay News) — Reflux symptoms return in about half of patients who undergo gastric bypass, according to a study published online June 4 in Alimentary Pharmacology & Therapeutics.

Abstract/Full Text

PDE5i Use Linked to Post-LVAD Right Heart Failure Events

WEDNESDAY, June 12, 2019 (HealthDay News) — For left ventricular assist device (LVAD) recipients, those on phosphodiesterase-5 inhibitors (PDE5i) have a higher incidence of severe early right heart failure (RHF), according to a study published online June 11 in Circulation: Heart Failure.

Abstract/Full Text

Editorial

USPSTF Issues Recommendations on HIV Screening, Prevention

TUESDAY, June 11, 2019 (HealthDay News) — The U.S. Preventive Services Task Force recommends preexposure prophylaxis (PrEP) and HIV screening for prevention of HIV infection. These recommendations form the basis of two final recommendation statements published online June 11 in the Journal of the American Medical Association.

Recommendation Statement – PrEP

Evidence Report – PrEP

Editorial

Recommendation Statement – Screening

Evidence Report – Nonpregnant

Evidence Report – Pregnant

Prescription Opioid Use Up Among Binge Drinkers

TUESDAY, June 11, 2019 (HealthDay News) — Prescription opioid misuse is more common among binge drinkers, with the prevalence of opioid misuse increasing with binge drinking frequency, according to a study published online June 11 in the American Journal of Preventive Medicine.

Abstract/Full Text

Pertussis Risk Up for Undervaccinated, Unvaccinated Children

TUESDAY, June 11, 2019 (HealthDay News) — Undervaccinated and unvaccinated children are at increased risk for pertussis, but most cases occur in vaccinated children further away from their last vaccine dose, according to a study published online June 10 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Diagnostic Testing, Antibiotics Overused in Pediatric CAP

TUESDAY, June 11, 2019 (HealthDay News) — Children with community-acquired pneumonia (CAP) often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011, according to a study published online May 20 in the Journal of the Pediatric Infectious Diseases Society.

Abstract/Full Text (subscription or payment may be required)

Chemoimmunotherapy Regimen Approved to Treat DLBCL

MONDAY, June 10, 2019 (HealthDay News) — Polivy (polatuzumab vedotin-piiq), a novel antibody-drug conjugate, received approval to treat patients with diffuse large B-cell lymphoma (DLBCL) in combination with bendamustine and rituximab, the U.S. Food and Drug Administration announced today. The combination was approved for patients whose disease has progressed or returned after at least two previous therapies.

More Information

Marketing OK’d for Device to Help Reduce IBS Symptoms in Adolescents

MONDAY, June 10, 2019 (HealthDay News) — The IB-Stim has received marketing approval from the U.S. Food and Drug Administration as the first medical device used to help alleviate functional abdominal pain in 11- to 18-year-old patients with irritable bowel syndrome (IBS), the agency announced Friday.

More Information

Untreated White Coat HTN May Increase Cardiovascular Risk

MONDAY, June 10, 2019 (HealthDay News) — The risk for cardiovascular events and all-cause mortality is increased for individuals with untreated white coat hypertension (WCH) but not for those with treated white coat effect (WCE), according to a review published online June 11 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Data Insufficient for Safety of Lithium During Breastfeeding

MONDAY, June 10, 2019 (HealthDay News) — There is variability in data relating to the safety of lithium during breastfeeding, according to a review published online June 10 in the International Review of Psychiatry.

Abstract/Full Text (subscription or payment may be required)

2003 to 2014 Saw Incidence of Herpes Zoster Drop in Children

MONDAY, June 10, 2019 (HealthDay News) — From 2003 to 2014, there was a decrease in herpes zoster (HZ) incidence among children, with lower incidence rates for varicella-vaccinated versus unvaccinated children, according to a study published online June 10 in Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Access to Health Care Has Little Impact on Longevity

MONDAY, June 10, 2019 (HealthDay News) — Health care has modest effects on extending life expectancy in the United States, while behavioral and social determinants may have larger effects, according to a review published in the May/June issue of the Annals of Family Medicine.

Abstract/Full Text

Antibiotic Prophylaxis Before Dental Work Often Unnecessary

FRIDAY, June 7, 2019 (HealthDay News) — Antibiotic prophylaxis before dental procedures is unnecessary more than 80 percent of the time, according to a study published online May 31 in JAMA Network Open.

Abstract/Full Text

Editorial

Naloxone Available in One in Three Philadelphia Pharmacies

FRIDAY, June 7, 2019 (HealthDay News) — Only one-third of Philadelphia pharmacies carry naloxone nasal spray and many pharmacies require a physician’s prescription, according to a study published online June 7 in JAMA Network Open.

Abstract/Full Text (subscription or payment may be required)

Individualized Care Plans Advised for T2DM With Heart Failure

FRIDAY, June 7, 2019 (HealthDay News) — Team-based care emphasizing development of individualized care plans is recommended for management of type 2 diabetes mellitus (T2DM) and heart failure, according to a scientific statement issued by the American Heart Association and Heart Failure Society of America and published online June 6 in Circulation.

Abstract/Full Text (subscription or payment may be required)

Misuse of Alprazolam Common in the United Kingdom

FRIDAY, June 7, 2019 (HealthDay News) — Nonmedical use of alprazolam is a significant issue in the United Kingdom, particularly among younger adults, according to a study published online June 4 in the British Journal of Clinical Pharmacology.

Abstract/Full Text

Model Explores How Statins Alter Multiple Sclerosis Outcomes

FRIDAY, June 7, 2019 (HealthDay News) — Simvastatin’s beneficial effects on clinical outcomes and brain atrophy in patients with multiple sclerosis (MS) are largely independent of cholesterol levels, according to a post hoc study published in the May 28 issue of the Proceedings of the National Academy of Sciences.

Abstract/Full Text

Testicular Cancer Treatment Does Not Up Risk for Offspring Birth Defects

THURSDAY, June 6, 2019 (HealthDay News) — Children of men with testicular germ-cell cancer (TGCC) have a modestly increased risk for congenital malformation (CM), which does not differ at pretreatment and posttreatment, according to a study published online June 4 in PLOS Medicine.

Abstract/Full Text

App Helps Pediatric Asthma Patients, Parents Self-Monitor

WEDNESDAY, June 5, 2019 (HealthDay News) — The electronic-AsthmaTracker (e-AT) app aids self-monitoring and improves asthma outcomes among pediatric patients and their parents, according to a study published in the June issue of Pediatrics.

Abstract/Full Text (subscription or payment may be required)

Emgality Receives First FDA Approval for Treating Cluster Headache

WEDNESDAY, June 5, 2019 (HealthDay News) — The U.S. Food and Drug Administration granted Emgality (galcanezumab-gnlm) solution the first approval for treating episodic cluster headache, the agency announced yesterday.

More Information

Dietary Supplements May Up Risk for Severe Medical Events

WEDNESDAY, June 5, 2019 (HealthDay News) — Consumption of dietary supplements, specifically those sold for muscle building, energy, and weight loss, is associated with an increased risk for severe medical events among individuals aged 0 to 25 years, according to a study published online June 5 in the Journal of Adolescent Health.

Abstract/Full Text (subscription or payment may be required)

Common Supplement Ingredient Could Harm Fetus, FDA Warns

TUESDAY, June 4, 2019 (HealthDay News) — A review by the U.S. Food and Drug Administration has revealed that vinpocetine, a compound found in many dietary supplements, may cause miscarriage or harm a developing fetus.

More Information

Zerbaxa Approved for Hospital-Acquired Bacterial Pneumonia

TUESDAY, June 4, 2019 (HealthDay News) — Zerbaxa (ceftolozane and tazobactam) has been approved for a new indication to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP) in patients aged 18 years and older, the U.S. Food and Drug Administration announced yesterday.

More Information

Nonsuicidal Self-Injury Rate Up in Sexual-Minority Youth

TUESDAY, June 4, 2019 (HealthDay News) — The prevalence of nonsuicidal self-injury (NSSI; i.e., intentional self-harm without wanting to die) is higher among sexual-minority youth than heterosexual youth, according to a research letter published online June 3 in JAMA Pediatrics.

Abstract/Full Text (subscription or payment may be required)

β-Blockers May Moderate Impact of Stress on Atrial Fibrillation

TUESDAY, June 4, 2019 (HealthDay News) — β-blockers can attenuate the impact of anger or stress on atrial fibrillation (AF), according to a study published online June 4 in HeartRhythm.

Abstract/Full Text (subscription or payment may be required)

Immunizations Up in California After Repeal of Nonmedical Exemptions

TUESDAY, June 4, 2019 (HealthDay News) — The repeal of nonmedical vaccine exemptions in California was only partially effective in improving vaccination coverage, according to a working paper issued by the National Bureau of Economic Research.

More Information

Many Buprenorphine Prescribers Not Offering New Appointments

MONDAY, June 3, 2019 (HealthDay News) — For callers reporting heroin use, many buprenorphine prescribers do not offer new appointments or rapid access to buprenorphine, according to a study published online June 4 in the Annals of Internal Medicine.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

FDA Takes Hard Look at CBD

MONDAY, June 3, 2019 (HealthDay News) — The U.S. Food and Drug Administration took a good look at the safety and effectiveness of cannabidiol (CBD) products on Friday, as it weighs how to best regulate the hemp-derived compound going forward.

CNN Article

HealthDay Article

Current Strategies for Measles Vaccination Insufficient

MONDAY, June 3, 2019 (HealthDay News) — Compulsory vaccination at school entry in addition to current immunization programs will be necessary in several high-income countries to prevent future measles resurgence, according to a study published online May 17 in BMC Medicine.

Abstract/Full Text

Guidelines Issued for Addressing Heart Disease Risk in HIV

MONDAY, June 3, 2019 (HealthDay News) — People living with HIV (PLWH) have an increased risk for cardiovascular disease (CVD), a risk that needs appropriate management and treatment, according to a scientific statement issued by the American Heart Association and published online June 3 in Circulation.

Abstract/Full Text (subscription or payment may be required)

Copyright © 2019 ScoutNews, LLC. All rights reserved.