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June 2019 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for June 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Medtronic Recalls Some Insulin Pumps Over Cybersecurity Concerns

FRIDAY, June 28, 2019 (HealthDay News) — The U.S. Food and Drug Administration announced Thursday that some high-tech insulin pumps made by Medtronic are being recalled for potential cybersecurity risks that could leave them vulnerable to hacking.

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Review: HPV Vaccination Program Has Considerable Impact

FRIDAY, June 28, 2019 (HealthDay News) — The human papillomavirus (HPV) vaccination program has had a considerable impact, according to a study published online June 26 in The Lancet.

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Editorial (subscription or payment may be required)

More Than 1 in 5 Young Men Use Disordered Eating to Bulk Up

THURSDAY, June 27, 2019 (HealthDay News) — Disordered eating to bulk up is common among young men and may be a warning sign of future health problems, according to a study published online June 20 in the International Journal of Eating Disorders.

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Migraine Prevalence Up for Food-Insecure Young Adults

THURSDAY, June 27, 2019 (HealthDay News) — The prevalence of migraine is elevated for young adults with food insecurity, according to a study published online June 24 in JAMA Neurology.

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Poststroke Headache Common in Pediatric Stroke Survivors

THURSDAY, June 27, 2019 (HealthDay News) — Remote poststroke headache is common among pediatric stroke survivors, according to a study recently published in Neurology: Clinical Practice.

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Educational Attainment Positively Linked to CVD Risk Factors

WEDNESDAY, June 26, 2019 (HealthDay News) — Educational attainment is positively associated with reduced smoking rates, depression, triglycerides, and heart disease, according to a study published online June 25 in PLOS Medicine.

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MSSP ACOs May Not Improve Spending, Quality of Care

WEDNESDAY, June 26, 2019 (HealthDay News) — After adjustment for the nonrandom exit of clinicians, the Medicare Shared Savings Program (MSSP) is not associated with improvements in spending or quality, according to a study published online June 18 in the Annals of Internal Medicine.

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Americans Concerned About Clinician Burnout

WEDNESDAY, June 26, 2019 (HealthDay News) — Nearly three-quarters of Americans are concerned about burnout among their clinicians, according to a survey released June 17 by the American Society of Health-System Pharmacists (ASHP).

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USPSTF Urges Interventions to Prevent Tobacco Use in Children

TUESDAY, June 25, 2019 (HealthDay News) — The U.S. Preventive Services Task Force (USPSTF) recommends that primary care physicians provide interventions to prevent school-aged children and adolescents from initiating tobacco use. This recommendation forms the basis of a draft recommendation statement, published online June 25 by the USPSTF.

Draft Recommendation Statement

Draft Evidence Review

Comment on Recommendation

Outcomes Poor Years After Radiation for Pediatric Glioma Survivors

TUESDAY, June 25, 2019 (HealthDay News) — Survivors of childhood low-grade gliomas treated with radiotherapy have poorer neuropsychological and socioeconomic-status (SES) outcomes, according to a study published online June 24 in Cancer.

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Anesthesia Tied to Neurocognitive Impairment in Childhood ALL Survivors

TUESDAY, June 25, 2019 (HealthDay News) — Multiple exposures to general anesthesia may be associated with neurocognitive impairment and brain imaging abnormalities in long-term survivors of childhood acute lymphoblastic leukemia (ALL), according to a study published online June 20 in JAMA Oncology.

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Nonchromosomal Birth Defects May Up Childhood Cancer Risk

MONDAY, June 24, 2019 (HealthDay News) — Children with nonchromosomal birth defects have a higher relative risk for cancer, though the absolute risk is still low, according to a study published online June 20 in JAMA Oncology.

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Editorial (subscription or payment may be required)

Many Trust Doctors, Nurses Over Other Sources of Health Advice

MONDAY, June 24, 2019 (HealthDay News) — Globally, about three-quarters of people trust doctors or nurses more than other sources when it comes to health advice, according to a report published online June 19 by the Wellcome Global Monitor.

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Antacid Use in First Year of Life Tied to Later Fracture Risk

MONDAY, June 24, 2019 (HealthDay News) — Infants who are given acid suppression therapy (AST) in their first year of life are more likely to subsequently break a bone, according to a study published online June 7 in Pediatrics.

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Editorial (subscription or payment may be required)

Rotavirus Vaccine Led to Reduced Disease Prevalence, Season Duration

MONDAY, June 24, 2019 (HealthDay News) — Implementation of rotavirus vaccination has reduced disease prevalence and season duration in the United States, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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FDA Expands Cystic Fibrosis Treatment Approval to Children Ages 6 to 12

FRIDAY, June 21, 2019 (HealthDay News) — The indication for a cystic fibrosis treatment, Symdeko (tezacaftor/ivacaftor) tablets, has been expanded to treat children ages 6 years and older with cystic fibrosis and certain genetic mutations, the U.S. Food and Drug Administration announced today.

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Obesity Prevalence Down in Young Children Enrolled in WIC

FRIDAY, June 21, 2019 (HealthDay News) — From 2010 to 2016, there was a decrease in the prevalence of obesity among children aged 2 through 4 years enrolled in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), according to a research letter published in the June 18 issue of the Journal of the American Medical Association.

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New England Journal of Medicine Picks New Editor-in-Chief

THURSDAY, June 20, 2019 (HealthDay News) — The new editor-in-chief of the prestigious New England Journal of Medicine is Eric J. Rubin, M.D., Ph.D., who was selected after a worldwide search and plans to start in September, according to the Massachusetts Medical Society, which publishes the journal.

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2018 to 2019 Influenza Season in U.S. Was Longest in 10 Years

THURSDAY, June 20, 2019 (HealthDay News) — In the United States, the 2018 to 2019 influenza season was of moderate severity and lasted 21 weeks, according to research published in the June 21 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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T2DM Risk in Offspring Up With Maternal Overweight, Obesity

THURSDAY, June 20, 2019 (HealthDay News) — Maternal obesity and overweight are associated with an increased risk for type 2 diabetes in offspring, according to a study published online June 19 in Diabetologia.

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Health Care Workers With ARIs Often Work While Symptomatic

THURSDAY, June 20, 2019 (HealthDay News) — Almost all health care workers (HCWs) with acute respiratory illness (ARI) report working at least one day while symptomatic, according to a study published online June 18 in Infection Control & Hospital Epidemiology.

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Sudden Death Can Occur in Full Spectrum of Epilepsies

WEDNESDAY, June 19, 2019 (HealthDay News) — Sudden unexpected death in epilepsy (SUDEP) can occur across the full spectrum of epilepsies, according to a study published online June 19 in Neurology.

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San Francisco Considering Banning Sales of E-Cigarettes

WEDNESDAY, June 19, 2019 (HealthDay News) — A ban on the sale and distribution of electronic cigarettes is being considered by San Francisco supervisors. If passed, it would be the first such ban by any city in the United States.

AP News Article

Hartford Courant Article

Surgeons’ Unprofessional Behavior Tied to Higher Complication Risk

WEDNESDAY, June 19, 2019 (HealthDay News) — Patients whose surgeons have higher numbers of coworker reports about unprofessional behavior may be at increased risk for postsurgical complications, according to a study published online June 19 in JAMA Surgery.

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Editorial (subscription or payment may be required)

Suicide Rates Peaked for Teens, Young Adults in 2017

WEDNESDAY, June 19, 2019 (HealthDay News) — Among adolescents and young adults, suicide rates increased to a high point in 2017, according to a research letter published in the June 18 issue of the Journal of the American Medical Association.

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Excess Weight Tied to Increased Risk for High BP in Young Children

WEDNESDAY, June 19, 2019 (HealthDay News) — Four-year-olds with excess weight have an increased risk for high blood pressure at age 6 years, according to a study published online June 12 in the European Journal of Preventive Cardiology.

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Pediatric T1DM Medication Adherence Drops on Weekends, Holidays

TUESDAY, June 18, 2019 (HealthDay News) — For children with type 1 diabetes, medication adherence is lower during school holidays and on weekends, according to a study recently published in the Archives of Disease in Childhood.

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Overall Cancer Survival Rates Up Among Adolescents, Young Adults

TUESDAY, June 18, 2019 (HealthDay News) — Cancer survival has improved among adolescents and young adults (AYA), but survival disparities are reported, according to a study published online June 12 in JNCI Cancer Spectrum.

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Cognitive Consequences Worse for Pediatric-Onset Multiple Sclerosis

TUESDAY, June 18, 2019 (HealthDay News) — Patients with pediatric-onset multiple sclerosis (POMS) have a more rapid reduction in information-processing efficiency over time in adulthood, and they are more likely to experience cognitive impairment than patients with adult-onset MS (AOMS), according to a study published online June 17 in JAMA Neurology.

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Editorial (subscription or payment may be required)

FDA Approves Victoza Injection for Children 10 Years and Older

TUESDAY, June 18, 2019 (HealthDay News) — Victoza (liraglutide) injection is now approved to treat type 2 diabetes in children 10 years and older, the U.S. Food and Drug Administration announced yesterday.

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Many Young Children Treated in ED for Injuries From Personal Care Products

TUESDAY, June 18, 2019 (HealthDay News) — A steady and persistent number of personal care product-related injuries were reported for young children from 2002 to 2016, most often occurring among those aged <2 years, according to a study published online June 16 in Clinical Pediatrics.

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CDC: U.S. Measles Cases Reach 1,044

MONDAY, June 17, 2019 (HealthDay News) — The number of measles cases in the United States so far this year has reached 1,044 in 28 states, the U.S. Centers for Disease Control and Prevention says.

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Drug Makers Challenge New Rule Requiring Drug Prices in TV Ads

MONDAY, June 17, 2019 (HealthDay News) — Three large drug makers have launched a legal challenge against the Trump administration’s rule requiring the prices of drugs to be included in television ads.

The New York Times Article

Recommendations Developed to Prepare Children for Camp

MONDAY, June 17, 2019 (HealthDay News) — In a policy statement issued by the American Academy of Pediatrics and published online June 17 in Pediatrics, recommendations are presented for the preparation of children for summer camps.

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U.S. Travelers Should Be Aware of Measles Risk in Europe

MONDAY, June 17, 2019 (HealthDay News) — U.S. travelers need to be aware of measles in Europe and should ensure children are adequately vaccinated, according to a study published online June 17 in Pediatrics.

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New York State Halts Religious Vaccine Exemption

FRIDAY, June 14, 2019 (HealthDay News) — Reacting to an ongoing measles outbreak, New York state has eliminated the religious exemption for not vaccinating children.

AP News Article

Head, Facial Injuries From Motorized Scooters on the Rise

FRIDAY, June 14, 2019 (HealthDay News) — Facial and head injuries from electric scooter accidents have tripled during the past decade, according to a study published online May 20 in the American Journal of Otolaryngology.

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Rotavirus Vaccination Tied to Lower Risk for T1DM in Children

FRIDAY, June 14, 2019 (HealthDay News) — Completion of full rotavirus vaccination appears to be associated with a reduction in the risk of type 1 diabetes in children, according to a study published online June 13 in Scientific Reports.

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Prenatal Antiepileptic Rx Exposure Ups Risk for Behavioral Issues

FRIDAY, June 14, 2019 (HealthDay News) — There is an increased risk for behavioral problems in children of mothers with epilepsy who take common antiepileptic drugs during pregnancy, according to a study published online June 5 in Epilepsia.

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Obesity During Teen Years Tied to Stiffening of Arteries

THURSDAY, June 13, 2019 (HealthDay News) — Persistently high fat mass during adolescence is associated with greater arterial stiffness, according to a study published online May 21 in The Lancet Child & Adolescent Health.

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Most Providers Unaware of Online Feedback About Themselves

WEDNESDAY, June 12, 2019 (HealthDay News) — Many health care providers in the United Kingdom have little direct experience with online feedback, rarely encourage it, and often view it as having little value for improving the quality of health services, according to a study published online June 2 in the Journal of Health Services Research & Policy.

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Study Confirms Teratogenicity of Valproic Acid, Topiramate

WEDNESDAY, June 12, 2019 (HealthDay News) — Valproic acid and topiramate are confirmed teratogens, according to a study published online June 12 in Neurology.

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Next-Gen Sequencing of CSF Improves Diagnosis of CNS Infections

WEDNESDAY, June 12, 2019 (HealthDay News) — Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF) obtained from patients with meningitis or encephalitis can improve diagnosis of neurologic infections, according to a study published in the June 13 issue of the New England Journal of Medicine.

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Approving Children’s Cancer Drugs Takes 6.5 Years Longer

WEDNESDAY, June 12, 2019 (HealthDay News) — For cancer drugs ultimately approved by the U.S. Food and Drug Administration, the median lag time from first-in-human to first-in-child trials is 6.5 years, according to a study published in the May issue of the European Journal of Cancer.

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Exposure to Air Pollution May Impact Children’s Cognitive Abilities

WEDNESDAY, June 12, 2019 (HealthDay News) — Early-life exposure to fine particulate matter (PM2.5) is associated with a reduction in fundamental cognitive abilities, according to a study recently published in Environmental Health Perspectives.

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USPSTF Issues Recommendations on HIV Screening, Prevention

TUESDAY, June 11, 2019 (HealthDay News) — The U.S. Preventive Services Task Force recommends preexposure prophylaxis (PrEP) and HIV screening for prevention of HIV infection. These recommendations form the basis of two final recommendation statements published online June 11 in the Journal of the American Medical Association.

Recommendation Statement – PrEP

Evidence Report – PrEP

Editorial

Recommendation Statement – Screening

Evidence Report – Nonpregnant

Evidence Report – Pregnant

Higher Levels of Exercise in Childhood Improve Heart Health

TUESDAY, June 11, 2019 (HealthDay News) — Engaging in higher levels of physical activity in childhood is associated with better cardiovascular health indicators, according to a study published online June 11 in Pediatrics.

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Pertussis Risk Up for Undervaccinated, Unvaccinated Children

TUESDAY, June 11, 2019 (HealthDay News) — Undervaccinated and unvaccinated children are at increased risk for pertussis, but most cases occur in vaccinated children further away from their last vaccine dose, according to a study published online June 10 in Pediatrics.

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Diagnostic Testing, Antibiotics Overused in Pediatric CAP

TUESDAY, June 11, 2019 (HealthDay News) — Children with community-acquired pneumonia (CAP) often receive diagnostic testing and antibiotic therapy despite publication of guidelines against their routine use in 2011, according to a study published online May 20 in the Journal of the Pediatric Infectious Diseases Society.

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Marketing OK’d for Device to Help Reduce IBS Symptoms in Adolescents

MONDAY, June 10, 2019 (HealthDay News) — The IB-Stim has received marketing approval from the U.S. Food and Drug Administration as the first medical device used to help alleviate functional abdominal pain in 11- to 18-year-old patients with irritable bowel syndrome (IBS), the agency announced Friday.

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Data Insufficient for Safety of Lithium During Breastfeeding

MONDAY, June 10, 2019 (HealthDay News) — There is variability in data relating to the safety of lithium during breastfeeding, according to a review published online June 10 in the International Review of Psychiatry.

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Cough Sound Analyzer Helps Differentiate Peds Respiratory Disorders

MONDAY, June 10, 2019 (HealthDay News) — An automated cough sound analyzer can serve as a diagnostic aid in the assessment of pediatric respiratory disorders, according to a study published online June 6 in Respiratory Research.

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2003 to 2014 Saw Incidence of Herpes Zoster Drop in Children

MONDAY, June 10, 2019 (HealthDay News) — From 2003 to 2014, there was a decrease in herpes zoster (HZ) incidence among children, with lower incidence rates for varicella-vaccinated versus unvaccinated children, according to a study published online June 10 in Pediatrics.

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Editorial (subscription or payment may be required)

Hyperglycemia in Pregnancy May Up Risk for Obesity in Offspring

MONDAY, June 10, 2019 (HealthDay News) — Pregnancy hyperglycemia at levels below the threshold for gestational diabetes mellitus (GDM) and maternal obesity are associated with childhood obesity, according to a study recently published in PLOS ONE.

Abstract/Full Text

Half an Hour of Sun Exposure Daily May Lower Risk for Pediatric IBD

MONDAY, June 10, 2019 (HealthDay News) — Higher sun exposure in the previous summer or winter is associated with a lower risk for having pediatric inflammatory bowel disease (IBD), according to a study recently published in the Journal of Pediatric Gastroenterology and Nutrition.

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Access to Health Care Has Little Impact on Longevity

MONDAY, June 10, 2019 (HealthDay News) — Health care has modest effects on extending life expectancy in the United States, while behavioral and social determinants may have larger effects, according to a review published in the May/June issue of the Annals of Family Medicine.

Abstract/Full Text

Rapid Cycling Work Roster Improves Resident Sleep Practices

THURSDAY, June 6, 2019 (HealthDay News) — A rapidly cycling work roster (RCWR) is effective in reducing weekly work hours and the occurrence of >16 consecutive-hour shifts as well as improving sleep duration of resident physicians, according to a study published online May 20 in SLEEP.

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Receipt of Breast Milk Increases With Gestational Age at Birth

THURSDAY, June 6, 2019 (HealthDay News) — Receipt of any breast milk varies with gestational age, ranging from 71.3 percent of extremely preterm infants to 84.6 percent of term infants, according to research published in the June 7 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Online Intervention May Cut Unnecessary Primary Care Visits

THURSDAY, June 6, 2019 (HealthDay News) — An online intervention may be effective in reducing a mother’s intention to bring her child to a primary care clinic for low-risk pediatric respiratory tract infections (RTIs), according to a study published in the May-June issue of the Annals of Family Medicine.

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Survey Indicates Physician Misconduct Is Underreported

THURSDAY, June 6, 2019 (HealthDay News) — Physician misconduct is being underreported and most Americans do not know where to file a complaint, according to a report published by the Federation of State Medical Boards (FSMB).

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Testicular Cancer Treatment Does Not Up Risk for Offspring Birth Defects

THURSDAY, June 6, 2019 (HealthDay News) — Children of men with testicular germ-cell cancer (TGCC) have a modestly increased risk for congenital malformation (CM), which does not differ at pretreatment and posttreatment, according to a study published online June 4 in PLOS Medicine.

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App Helps Pediatric Asthma Patients, Parents Self-Monitor

WEDNESDAY, June 5, 2019 (HealthDay News) — The electronic-AsthmaTracker (e-AT) app aids self-monitoring and improves asthma outcomes among pediatric patients and their parents, according to a study published in the June issue of Pediatrics.

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Dietary Supplements May Up Risk for Severe Medical Events

WEDNESDAY, June 5, 2019 (HealthDay News) — Consumption of dietary supplements, specifically those sold for muscle building, energy, and weight loss, is associated with an increased risk for severe medical events among individuals aged 0 to 25 years, according to a study published online June 5 in the Journal of Adolescent Health.

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Costs, Complications Up for Minorities in Cleft Palate Repair

TUESDAY, June 4, 2019 (HealthDay News) — Racial-minority populations incur higher costs and experience higher rates of complications in cleft palate repair, according to a study published in the June issue of Plastic and Reconstructive Surgery.

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Staphylococcus aureus Linked to Food Sensitization in Eczema

TUESDAY, June 4, 2019 (HealthDay News) — For children with eczema, Staphylococcus aureus (S. aureus) colonization is associated with food sensitization and allergy independent of eczema severity, according to a study published online May 31 in the Journal of Allergy and Clinical Immunology.

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Immunizations Up in California After Repeal of Nonmedical Exemptions

TUESDAY, June 4, 2019 (HealthDay News) — The repeal of nonmedical vaccine exemptions in California was only partially effective in improving vaccination coverage, according to a working paper issued by the National Bureau of Economic Research.

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ACP Issues Position on Response to Physician Impairment

MONDAY, June 3, 2019 (HealthDay News) — Providing assistance for physician impairment and rehabilitation is addressed in a position statement issued by the American College of Physicians and published online June 4 in the Annals of Internal Medicine.

Abstract/Full Text

Editorial (subscription or payment may be required)

Number, Rate of Detergent Pod Exposures Modestly Declined

MONDAY, June 3, 2019 (HealthDay News) — In recent years, the number and rate of liquid laundry detergent packet exposures has declined slightly among children younger than 6 years, according to a study published online June 3 in Pediatrics.

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Current Strategies for Measles Vaccination Insufficient

MONDAY, June 3, 2019 (HealthDay News) — Compulsory vaccination at school entry in addition to current immunization programs will be necessary in several high-income countries to prevent future measles resurgence, according to a study published online May 17 in BMC Medicine.

Abstract/Full Text

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