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July 2019 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for July 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Hot Pavement Can Burn Feet in Seconds

WEDNESDAY, July 31, 2019 (HealthDay News) — Hot pavement poses a burn risk, particularly when outside temperatures reach greater than 95 degrees Fahrenheit, according to a study published in the July/August issue of the Journal of Burn Care & Research.

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Likelihood of Trying Drugs for the First Time Higher in the Summer

WEDNESDAY, July 31, 2019 (HealthDay News) — Summer appears to be a risk factor for drug use initiation, according to a study published online July 23 in the Journal of General Internal Medicine.

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Burnout Symptoms May Up Racial Bias Among Resident Physicians

WEDNESDAY, July 31, 2019 (HealthDay News) — Symptoms of burnout seem to be associated with greater explicit and implicit racial bias among resident physicians, according to a study published online July 26 in JAMA Network Open.

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Editorial

$70 Million Settlement Reached in Generic Drug Delay Case

TUESDAY, July 30, 2019 (HealthDay News) — Three drug companies will pay a total of nearly $70 million to California to settle charges of delaying the sale of generic drugs to keep brand-name drug prices high, the state’s attorney general said Monday.

AP News Article

CDC: General Fertility Rate, Teen Birth Rate Decreasing in U.S.

TUESDAY, July 30, 2019 (HealthDay News) — From 2017 to 2018, there were decreases in the U.S. general fertility rate and the teen birth rate, according to a July data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Oil, Gas Well Exposure May Up Risk for Congenital Heart Defects

TUESDAY, July 30, 2019 (HealthDay News) — Pregnant women living near more oil and natural gas development activity have a greater chance of giving birth to children with congenital heart defects (CHDs), according to a study published online July 18 in Environment International.

Abstract/Full Text

Global Burden of Childhood Cancers Examined

TUESDAY, July 30, 2019 (HealthDay News) — Childhood cancers have a considerable disability-adjusted life-year (DALY) burden, which disproportionately affects countries with low resources, according to a study published online July 29 in The Lancet Oncology.

Abstract/Full Text

Editorial

Earlier Puberty in Swedish Boys Only Partially Due to Higher BMI

TUESDAY, July 30, 2019 (HealthDay News) — There is a secular trend for earlier pubertal timing among Swedish boys, according to a study published online July 22 in JAMA Pediatrics.

Abstract/Full Text

Editorial (subscription or payment may be required)

National Norms Developed for Assessing Medical School Empathy

TUESDAY, July 30, 2019 (HealthDay News) — National norms have been developed for assessing empathy among men and women at different levels of medical school education, according to a study published in the August issue of the Journal of the American Osteopathic Association.

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Lifesaving Drug for Infants Costs $2.1 Million a Dose

MONDAY, July 29, 2019 (HealthDay News) — Its extremely high price tag means that a lifesaving medication to treat young children with spinal muscular atrophy is simply too expensive for most families.

NBC News Article

Consumer Products Tied to Three-Fourths of Youth Brain Injuries

MONDAY, July 29, 2019 (HealthDay News) — Nearly three-quarters of traumatic brain injuries (TBI) in children and teens are attributable to consumer products that are regulated by the U.S. Consumer Product Safety Commission, according to a study published online July 29 in the journal Brain Injury.

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Pediatricians Have Role to Play in Addressing Racism

MONDAY, July 29, 2019 (HealthDay News) — Pediatricians should play a role in advocating to redress biases and inequalities in the health system and other systems, according to a policy statement published online July 29 in Pediatrics.

Policy Statement

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

JUUL E-Cigarettes Never Meant for Teens, Company Cofounder Says

FRIDAY, July 26, 2019 (HealthDay News) — JUUL developed its electronic cigarette for adult smokers who want to stop and never intended it to be adopted by underage teenagers, company cofounder James Monsees told a U.S. House subcommittee on Thursday, adding that “combating underage use” is the company’s highest priority, the Associated Press reported.

AP News Article

Most Pediatric In-Flight Medical Events Handled by Crew

THURSDAY, July 25, 2019 (HealthDay News) — Most pediatric in-flight medical events (IFMEs) are handled by crewmembers, according to a study published online July 25 in the Annals of Emergency Medicine.

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BPA Substitute Chemicals Linked to Obesity in Children

THURSDAY, July 25, 2019 (HealthDay News) — Exposure to bisphenol A (BPA) substitute chemicals, bisphenol S (BPS) and bisphenol F (BPF), is associated with obesity among children, according to a study published online July 25 in the Journal of the Endocrine Society.

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Exposure to Air Pollution Tied to Raised Odds of NICU Admission

THURSDAY, July 25, 2019 (HealthDay News) — Acute exposure to pollutants in the week prior to delivery and day of delivery is associated with increased odds of neonatal intensive care unit (NICU) admission, according to a study published online July 12 in the Annals of Epidemiology.

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In-Hospital Cardiac Arrests in the U.S. May Be Underestimated

WEDNESDAY, July 24, 2019 (HealthDay News) — More patients suffer cardiac arrest in U.S. hospitals each year than previously estimated — with rates about 38 percent greater for adults and 18 percent greater for children, according to a study published online July 9 in Circulation: Cardiovascular Quality and Outcomes.

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2001 to 2017 Saw Increase in Suicides in African-American Teens

TUESDAY, July 23, 2019 (HealthDay News) — From 2001 to 2017, the rate of suicides among African-American (AA) adolescents increased, according to a study published in the August issue of the Journal of Community Health.

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Reducing Air Pollution Could Cut Rates of Childhood Asthma

TUESDAY, July 23, 2019 (HealthDay News) — Statistical models demonstrate how targeting certain air pollutants could reduce the incidence of childhood asthma, according to a study published online July 22 in the Proceedings of the National Academy of Sciences.

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Stimulant Treatment Has Strong Protective Effect in ADHD

TUESDAY, July 23, 2019 (HealthDay News) — For youth with attention-deficit/hyperactivity disorder (ADHD), stimulants have strong protective effects on functional outcomes, according to a study published online July 23 in the Journal of Adolescent Health.

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Nonprescription Antibiotic Use Seems Prevalent in the United States

MONDAY, July 22, 2019 (HealthDay News) — Nonprescription antibiotic use appears to be prevalent in the United States, according to a review published online July 23 in the Annals of Internal Medicine.

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State-Level Firearm Ownership Linked to Domestic Firearm Homicide

MONDAY, July 22, 2019 (HealthDay News) — There is an association for state-level firearm ownership rates with domestic, but not nondomestic, firearm homicide, according to a study published online July 22 in the American Journal of Preventive Medicine.

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Pediatricians Can Play Role in Ensuring School Readiness

MONDAY, July 22, 2019 (HealthDay News) — Social-emotional and behavioral skills are important for school readiness, and preschoolers with attention-deficit/hyperactivity disorder (ADHD) have increased odds of impaired school readiness, according to a technical report and study published online July 22 in Pediatrics.

Abstract/Full Text – Technical Report

Abstract/Full Text – Study (subscription or payment may be required)

More Screen Time Ups Risk for Depression in Adolescents

MONDAY, July 22, 2019 (HealthDay News) — Increases in time spent on social media, computers, and watching television are linked to a corresponding increase in depression in adolescents, according to a study published online July 15 in JAMA Pediatrics.

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New ACC/AHA Guidelines Detect More Cases of Gestational Hypertension

MONDAY, July 22, 2019 (HealthDay News) — Adopting the 2017 American College of Cardiology/American Heart Association guidelines for hypertension resulted in an increase in the prevalence of high blood pressure in pregnant women, according to a study published in the July 5 issue of Circulation Research.

Abstract/Full Text

Editorial

Family Support May Improve Asthma Outcomes in Poor Youth

FRIDAY, July 19, 2019 (HealthDay News) — Better family relationships are associated with better asthma management behaviors and outcomes for those living in neighborhoods characterized as dangerous and/or disorderly, according to a study published online July 18 in Pediatrics.

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EPA Will Not Ban Pesticide Linked to Brain Harm in Children

FRIDAY, July 19, 2019 (HealthDay News) — Even though the pesticide chlorpyrifos has been linked to brain harm in children, it will not be banned in the United States, the Environmental Protection Agency announced Thursday.

The New York Times Article

Higher eGFR at Dialysis Initiation Tied to Lower Survival in Children

FRIDAY, July 19, 2019 (HealthDay News) — In children with end-stage renal disease (ESRD), a higher estimated glomerular filtration rate (eGFR) at dialysis initiation is associated with lower survival, particularly among children whose initial treatment method is hemodialysis, according to a study published online July 18 in the Journal of the American Society of Nephrology.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

Transfers Up for Mental Health Disorders in Uninsured Children

THURSDAY, July 18, 2019 (HealthDay News) — For children presenting to the emergency department with a mental health disorder, the likelihood of transfer is increased for those without insurance, according to a study published online July 1 in Pediatric Emergency Care.

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About One in 20 Patients Exposed to Preventable Harm

THURSDAY, July 18, 2019 (HealthDay News) — The pooled prevalence of preventable patient harm is 6 percent across a range of medical settings globally, according to a review published online July 17 in The BMJ.

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Editorial

Educational Handout May Increase Receipt of Child Flu Shot

TUESDAY, July 16, 2019 (HealthDay News) — Providing an educational handout about influenza disease in the waiting room before a pediatric provider visit may increase receipt of child influenza vaccine, according to a study published online July 8 in Pediatrics.

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Obesity Linked to Increased Risk for Pediatric Multiple Sclerosis

MONDAY, July 15, 2019 (HealthDay News) — Obesity seems to be associated with increased odds of pediatric multiple sclerosis (MS), according to a study published online July 15 in JAMA Neurology.

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Increase Seen in Foster Care Entries Due to Parental Drug Use

MONDAY, July 15, 2019 (HealthDay News) — The number of foster care entries attributable to parental drug use increased considerably from 2000 to 2017, according to a research letter published online July 15 in JAMA Pediatrics.

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Firearm-Related Pediatric Mortality Down With Stricter Laws

MONDAY, July 15, 2019 (HealthDay News) — States with stricter firearm legislation have lower rates of firearm-related pediatric mortality, according to a study published online July 15 in Pediatrics.

Abstract/Full Text

Editorial

Prepregnancy Surgery Linked to Risk for Neonatal Abstinence Syndrome

MONDAY, July 15, 2019 (HealthDay News) — Prepregnancy surgery is associated with elevated neonatal abstinence syndrome risk in future pregnancies, according to a study published in the July 15 issue of CMAJ, the journal of the Canadian Medical Association.

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Race, Neighborhood Impact Bystander CPR in Pediatric OHCA

MONDAY, July 15, 2019 (HealthDay News) — For pediatric out-of-hospital cardiac arrest (OHCA), racial and neighborhood characteristics are associated with bystander cardiopulmonary resuscitation (BCPR), according to a study published online July 10 in the Journal of the American Heart Association.

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Prenatal Opioid Exposure Harms Long-Term Child Development

FRIDAY, July 12, 2019 (HealthDay News) — Prenatal opioid exposure (POE) is negatively associated with neurocognitive and physical development in offspring from the age of 6 months into school age, according to a study published online July 12 in JAMA Network Open.

Abstract/Full Text

Rabies Warning Issued for Walt Disney World Resort Area

FRIDAY, July 12, 2019 (HealthDay News) — A rabies warning was issued for Walt Disney World Resort and the surrounding area after a rabid cat scratched two employees.

USA Today Article

Feeding Examination Can Avert Surgical Frenotomy Procedures

FRIDAY, July 12, 2019 (HealthDay News) — Most patients referred for ankyloglossia can benefit from intervention strategies other than surgical procedures, according to a study published online July 11 in JAMA Otolaryngology-Head & Neck Surgery.

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U.S. Health, Economic Burden of Uncontrolled Asthma Projected

FRIDAY, July 12, 2019 (HealthDay News) — The economic burden of uncontrolled asthma is considerable and is projected to continue increasing, according to a study recently published in the American Journal of Respiratory and Critical Care Medicine.

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Editorial (subscription or payment may be required)

Serious Misdiagnosis-Related Harms Mostly Due to ‘Big Three’

FRIDAY, July 12, 2019 (HealthDay News) — Vascular events, infections, and cancers account for about three-quarters of serious misdiagnosis-related harms, according to a study published online July 11 in Diagnosis.

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Capping Work Hours in Residency Does Not Impact Outcomes Later

THURSDAY, July 11, 2019 (HealthDay News) — Exposure of U.S. physicians to work-hour reforms during residency training is not associated with post-training differences in patient mortality, readmissions, or costs of care, according to a study published online July 11 in The BMJ.

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Exposure to 2009 pH1N1 Vaccine During Pregnancy Seems Safe

THURSDAY, July 11, 2019 (HealthDay News) — Exposure to the 2009 pandemic H1N1 (pH1N1) influenza vaccine in pregnancy is not associated with most negative health outcomes among offspring, according to a study published online July 10 in The BMJ.

Abstract/Full Text

Editorial (subscription or payment may be required)

Health Care Professionals Exhibit Gender Bias

THURSDAY, July 11, 2019 (HealthDay News) — Survey results show that health care professionals have implicit and explicit gender bias, according to a study published online July 5 in JAMA Network Open.

Abstract/Full Text

Editorial

Risk for Cancer Higher in Those With Congenital Heart Disease

WEDNESDAY, July 10, 2019 (HealthDay News) — Children and young adult patients with congenital heart disease (CHD) have an increased risk for developing cancer, according to a study published online July 5 in JAMA Network Open.

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Editorial

Guidance Updated for Managing Infants at Risk for Group B Strep

WEDNESDAY, July 10, 2019 (HealthDay News) — Guidelines for the management and treatment of group B streptococcal (GBS) disease in infants were published online July 8 in Pediatrics.

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New WIC Food Options Improve Maternal, Birth Outcomes

WEDNESDAY, July 10, 2019 (HealthDay News) — Revisions to the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) food package are associated with beneficial impacts on maternal and birth outcomes, according to a study published online July 1 in JAMA Pediatrics.

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Editorial (subscription or payment may be required)

CDC Updates Data on Cases Meeting Criterion for Acute Flaccid Myelitis

TUESDAY, July 9, 2019 (HealthDay News) — Clinical and laboratory data have been updated for cases that met the clinical criterion for acute flaccid myelitis (AFM) in the United States during 2018, according to a Vital Signs report published in the July 9 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Fewer New Measles Cases Reported Last Week in U.S.

TUESDAY, July 9, 2019 (HealthDay News) — There were just over a dozen measles cases reported last week in the United States, the U.S. Centers for Disease Control and Prevention said Monday.

CNN Article

More Information: CDC

Rule Requiring Drug Prices in TV Ads Blocked by Judge

TUESDAY, July 9, 2019 (HealthDay News) — A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge.

The New York Times Article

EHR System-Generated In-Basket Messages Linked to Burnout

TUESDAY, July 9, 2019 (HealthDay News) — Receipt of more than the average number of electronic health record (EHR) system-generated in-basket messages is associated with an increased probability of physician burnout, according to a study published in the July 1 issue of Health Affairs.

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Adults With Cerebral Palsy at Higher Risk for Osteoporosis

TUESDAY, July 9, 2019 (HealthDay News) — Cerebral palsy (CP) is associated with an increased risk for osteoporosis and osteoarthritis, according to a study published in the August issue of Bone.

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School Performance Down With Adverse Childhood Experiences

TUESDAY, July 9, 2019 (HealthDay News) — Children’s school performance and attitudes decline as their adverse childhood experiences (ACEs) increase, according to a study published online July 8 in Pediatrics.

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Editorial (subscription or payment may be required)

Risk of Stillbirth Increases in Pregnancies Past 37 Weeks

MONDAY, July 8, 2019 (HealthDay News) — The risk for stillbirth increases the longer a pregnancy continues past 37 weeks of gestation, according to a meta-analysis published online July 2 in PLOS Medicine.

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Early Warning Signs May Predate Eating Disorder Onset

MONDAY, July 8, 2019 (HealthDay News) — Early warning signs may help providers identify eating disorders earlier, according to a study published online July 1 in the British Journal of Psychiatry.

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Neuropsychiatric Morbidity Up With Synthetic Cannabinoid Use in Teens

MONDAY, July 8, 2019 (HealthDay News) — Synthetic cannabinoid (SC) exposure is associated with increased odds of neuropsychiatric morbidity versus cannabis exposure among adolescents presenting to the emergency department, according to a study published online July 8 in Pediatrics.

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IL-6 Level May Predict Symptom Duration in Concussed Athletes

WEDNESDAY, July 3, 2019 (HealthDay News) — For concussed athletes, interleukin (IL)-6 and IL-1 receptor antagonist (IL-1RA) are significantly elevated at six hours after concussion, and IL-6 levels are associated with symptom duration, according to a study published online July 3 in Neurology.

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Male Students Affected More by Poor Diet in First Year of College

WEDNESDAY, July 3, 2019 (HealthDay News) — During the first year of university life, both male and female students make poor dietary choices, which are associated with increases in body weight and fat composition; however, male students appear to be affected more than female students, according to a study published online July 3 in PLOS ONE.

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Interventions Linked to Drop in Unvaccinated Kindergartners

WEDNESDAY, July 3, 2019 (HealthDay News) — Statewide legislative and educational interventions are associated with a reduction in the yearly rates of kindergartners without up-to-date vaccination status, according to a study published in the July 2 issue of the Journal of the American Medical Association.

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Editorial (subscription or payment may be required)

Lack of Evidence for Treating Chronic Pain in Children

WEDNESDAY, July 3, 2019 (HealthDay News) — There is a lack of evidence on the efficacy and safety of pharmacological treatments for chronic pain in children, according to research published online June 19 in PAIN.

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Most U.S. Adults Are Concerned About Antibiotic Resistance

WEDNESDAY, July 3, 2019 (HealthDay News) — Most U.S. adults have heard of and are concerned about antibiotic resistance, but 45 percent report having not taken antibiotics as prescribed, according to a report published online June 21 by the Kaiser Family Foundation.

More Information

Vermont Places 92 Percent Tax on E-Cigarettes

TUESDAY, July 2, 2019 (HealthDay News) — A 92 percent tax on electronic cigarettes took effect in Vermont on Monday as the state tries to reduce young people’s use of the devices.

CBS News Article

Adverse Outcomes Up for Pregnant Women With Migraine

TUESDAY, July 2, 2019 (HealthDay News) — Pregnant women with migraine and their offspring have increased risks of several adverse pregnancy and neonatal outcomes, according to a study recently published in Headache.

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Anti-Vaccine Movement a ‘Man-Made’ Health Crisis, Scientists Warn

TUESDAY, July 2, 2019 (HealthDay News) — The anti-vaccination movement is now a global crisis, an international panel of scientists say, and everyone must do more to combat it.

Press Release

The Salzburg Statement on Vaccination Acceptance

Guidance Issued for Management of Fontan Circulation

TUESDAY, July 2, 2019 (HealthDay News) — A scientific statement with recommendations for follow-up care in patients with Fontan circulation surviving into adulthood was published online July 1 in Circulation.

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In Utero Opioid Exposure Tied to Poor Outcomes Throughout Childhood

TUESDAY, July 2, 2019 (HealthDay News) — In utero exposure to opioids is associated with higher risks for short- and long-term adverse outcomes, including preterm birth and neurodevelopmental and physical health disorders in children, according to a study published online June 28 in JAMA Network Open.

Abstract/Full Text

Editorial

Guide Addresses Medical Issues Relevant to Transgender Persons

TUESDAY, July 2, 2019 (HealthDay News) — A guide to help clinicians understand the medical issues relevant to transgender persons, based on a review of current evidence, was published online July 2 in the Annals of Internal Medicine.

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Considerable Number of Patients Receive Surprise Hospital Charges

TUESDAY, July 2, 2019 (HealthDay News) — Eighteen percent of all emergency department visits and 16 percent of in-network hospital stays have at least one out-of-network charge, according to a report published June 20 by the Kaiser Family Foundation.

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Core Components of Teen Mental Health Interventions ID’d

MONDAY, July 1, 2019 (HealthDay News) — Three program components of interventions to promote mental health and prevent mental disorders and risk behaviors during adolescence have a significant effect on multiple outcomes, according to a review published online July 1 in Pediatrics.

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Editorial (subscription or payment may be required)

Low Vitamin D in Early Life May Up Risk of Elevated Systolic BP

MONDAY, July 1, 2019 (HealthDay News) — Low vitamin D status and trajectory in early life are associated with increased risk of elevated systolic blood pressure (SBP) during childhood, according to a study published online July 1 in Hypertension.

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