Home News Diabetes News July 2019 Briefing – Diabetes & Endocrinology

July 2019 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for July 2019. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Oral Semaglutide Reduces HbA1c, Weight in Patients With T2DM

WEDNESDAY, July 31, 2019 (HealthDay News) — Compared with placebo, oral semaglutide monotherapy is associated with superior and clinically relevant improvements in glycated hemoglobin (HbA1c) and weight loss among patients with type 2 diabetes, according to a study published online July 18 in Diabetes Care.

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Burnout Symptoms May Up Racial Bias Among Resident Physicians

WEDNESDAY, July 31, 2019 (HealthDay News) — Symptoms of burnout seem to be associated with greater explicit and implicit racial bias among resident physicians, according to a study published online July 26 in JAMA Network Open.

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$70 Million Settlement Reached in Generic Drug Delay Case

TUESDAY, July 30, 2019 (HealthDay News) — Three drug companies will pay a total of nearly $70 million to California to settle charges of delaying the sale of generic drugs to keep brand-name drug prices high, the state’s attorney general said Monday.

AP News Article

National Norms Developed for Assessing Medical School Empathy

TUESDAY, July 30, 2019 (HealthDay News) — National norms have been developed for assessing empathy among men and women at different levels of medical school education, according to a study published in the August issue of the Journal of the American Osteopathic Association.

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SGLT-2 Inhibitor Use Not Linked to Increased Risk for UTI Events

TUESDAY, July 30, 2019 (HealthDay News) — Initiation of therapy with sodium-glucose cotransporter-2 (SGLT-2) inhibitors for type 2 diabetes mellitus is not associated with an increased risk for urinary tract infection (UTI) events compared with initiation of other second-line antidiabetic medications, according to a study published online July 30 in the Annals of Internal Medicine.

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Random Plasma Glucose Levels Can Predict Diabetes Diagnosis

MONDAY, July 29, 2019 (HealthDay News) — Random plasma glucose (RPG) levels can predict development of diabetes, according to a study published online July 19 in PLOS ONE.

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Adherence to Aerobic Activity Guidelines Not Up Since 2008

FRIDAY, July 26, 2019 (HealthDay News) — Since publication of the Physical Activity Guidelines for Americans (PAG) in 2008, there has been no increase in adherence to aerobic activity guidelines, while sedentary time has increased, according to a study published online July 26 in JAMA Network Open.

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Daily E-Cigarette Use May Increase Prolonged Cigarette Abstinence

FRIDAY, July 26, 2019 (HealthDay News) — Daily electronic-cigarette use is associated with increased odds of prolonged regular cigarette smoking abstinence, according to a study published online July 11 in Nicotine & Tobacco Research.

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Mortality Up in Women With Central Obesity, Regardless of BMI

FRIDAY, July 26, 2019 (HealthDay News) — Women with normal-weight central obesity have increased mortality risk compared with normal weight women with no central obesity, according to a study published online July 24 in JAMA Network Open.

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Vitamin D Supplementation Beneficial for Glucose Metabolism

FRIDAY, July 26, 2019 (HealthDay News) — Vitamin D3 supplementation can improve glucose metabolism in patients at high risk of diabetes or with newly-diagnosed diabetes, according to a study published online July 1 in the European Journal of Endocrinology.

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Review Supports Testosterone for Low Sexual Desire in Women

FRIDAY, July 26, 2019 (HealthDay News) — For postmenopausal women with low sexual desire causing distress, testosterone is an effective treatment, with a preference for nonoral administration, according to a review published online July 25 in the The Lancet Diabetes & Endocrinology.

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Thyroidectomy Complication Rate Down When Surgeon Volume Up

FRIDAY, July 26, 2019 (HealthDay News) — For patients undergoing total thyroidectomy, the occurrence rate of complications decreases as annual surgeon volumes increase, according to a study published online July 25 in JAMA Otolaryngology-Head & Neck Surgery.

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Higher Fasting Plasma Glucose May Up Pancreatic Cancer Risk

THURSDAY, July 25, 2019 (HealthDay News) — The incidence rate of pancreatic cancer increases with rising fasting blood glucose levels, even within the normal range, according to a study published online July 24 in the Journal of Clinical Endocrinology & Metabolism.

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BPA Substitute Chemicals Linked to Obesity in Children

THURSDAY, July 25, 2019 (HealthDay News) — Exposure to bisphenol A (BPA) substitute chemicals, bisphenol S (BPS) and bisphenol F (BPF), is associated with obesity among children, according to a study published online July 25 in the Journal of the Endocrine Society.

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Minor Changes in BMD Seen With Tenofovir PrEP in Short Term

THURSDAY, July 25, 2019 (HealthDay News) — Tenofovir preexposure prophylaxis (PrEP) therapy does not appear to be associated with clinically significant declines in bone mineral density (BMD) in the short term, according to a study published online June 19 in AIDS Research and Human Retroviruses.

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Mediterranean Diet May Reduce Gestational Diabetes Risk

WEDNESDAY, July 24, 2019 (HealthDay News) — Following a Mediterranean diet in pregnancy does not reduce the risk for adverse maternal and offspring complications but may reduce the odds of gestational diabetes, according to a study published online July 23 in PLOS Medicine.

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CDC: Mortality Rates Continue to Decrease for Hispanic Adults

WEDNESDAY, July 24, 2019 (HealthDay News) — Age-adjusted death rates decreased for Hispanic adults from 2000 through 2017, while for non-Hispanic white and non-Hispanic black adults, the rates have remained stable since 2011-2012, according to a July data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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Periop Diabetic Ketoacidosis Seen in Patients on SGLT2 Inhibitors

WEDNESDAY, July 24, 2019 (HealthDay News) — Sodium-glucose cotransporter-2 inhibitor (SGLT2i)-associated diabetic ketoacidosis (DKA) may occur after surgery even in patients with normal or near-normal blood glucose levels, according to a review published in the July issue of the British Journal of Anaesthesia.

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Weight Loss Experiences Differ for Minority Groups With T2DM

WEDNESDAY, July 24, 2019 (HealthDay News) — Daily self-weighing uptake is considerable among minority subgroups with type 2 diabetes and is associated with year 1 weight loss among African-Americans, according to a study published online July 24 in Obesity.

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Metformin May Lower Dementia Risk in Black Patients With T2DM

WEDNESDAY, July 24, 2019 (HealthDay News) — Metformin use is associated with a substantially lower risk for dementia among younger African-American patients with diabetes compared with sulfonylurea initiation, according to a study published in the July/August issue of the Annals of Family Medicine.

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Senate Bill Would Reduce Drug Costs for Seniors

TUESDAY, July 23, 2019 (HealthDay News) — A bill to reduce prescription drug costs for millions of Medicare recipients and lower federal and state health costs has been introduced by two U.S. senators.

AP News Article

One in Five Workers Exposed to Secondhand Smoke on the Job

TUESDAY, July 23, 2019 (HealthDay News) — One in five nonsmoking workers report exposure to secondhand tobacco smoke (SHS) at work, according to research published in the July 12 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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T2DM Increases Gastric Cancer Risk After H. Pylori Eradication

TUESDAY, July 23, 2019 (HealthDay News) — Type 2 diabetes mellitus increases the risk for gastric cancer after treatment for Helicobacter pylori infection, according to a study published online July 11 in Diabetes Care.

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Plant-Based Diets Inversely Linked to Risk for Type 2 Diabetes

MONDAY, July 22, 2019 (HealthDay News) — Plant-based dietary patterns seem to be beneficial for the primary prevention of type 2 diabetes, especially when the diets are enriched with healthful plant-based foods, according to a review published online July 22 in JAMA Internal Medicine.

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FRAX Score Underestimates Risk for Fracture in Multiple Sclerosis

FRIDAY, July 19, 2019 (HealthDay News) — Multiple sclerosis (MS) is a risk factor for major fractures independent of the Fracture Risk Assessment tool (FRAX) score, according to a study published in the June issue of the Journal of Bone and Mineral Research.

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Factors Associated With Thyroid Cancer Overtreatment Identified

FRIDAY, July 19, 2019 (HealthDay News) — One-fourth of patients receive unnecessary treatment with radioactive iodine after surgery for low-risk papillary thyroid cancer, according to a study published in the June issue of Surgical Oncology.

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Financial Incentives Help People Stop Smoking

FRIDAY, July 19, 2019 (HealthDay News) — Financial incentives do seem to help people quit smoking, according to a study published July 17 in the Cochrane Library.

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Excess Risk for Diabetes-Linked Heart Failure Greater in Women

FRIDAY, July 19, 2019 (HealthDay News) — The excess risk for heart failure associated with diabetes is significantly greater in women than men, according to a meta-analysis published online July 18 in Diabetologia.

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CDC: Prevalence of Smoking Quit Attempts Unchanged in Most States

THURSDAY, July 18, 2019 (HealthDay News) — During 2011 to 2017, the prevalence of quit attempts in adult smokers did not change significantly in 44 states and increased in only four states, according to research published in the July 19 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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CDC Assesses Burden of Eye Disorders in Adults With Diabetes

THURSDAY, July 18, 2019 (HealthDay News) — Eye disorders frequently affect adults aged 45 years and older with diagnosed diabetes, and disorders are more common for those with diagnosed diabetes for 10 years or more, according to a July data brief published by the U.S. Centers for Disease Control and Prevention National Center for Health Statistics.

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About One in 20 Patients Exposed to Preventable Harm

THURSDAY, July 18, 2019 (HealthDay News) — The pooled prevalence of preventable patient harm is 6 percent across a range of medical settings globally, according to a review published online July 17 in The BMJ.

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Most Adults Favor Cutting Nicotine Levels in Cigarettes

TUESDAY, July 16, 2019 (HealthDay News) — Most adults favor requiring cigarette makers to lower the level of nicotine in cigarettes, according to a study published online July 11 in the American Journal of Preventive Medicine.

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Alirocumab Cuts CV Absolute Risk the Most for Those With Diabetes

TUESDAY, July 16, 2019 (HealthDay News) — Among those receiving alirocumab in addition to statin therapy to reduce the risk for another cardiovascular event after a recent acute coronary syndrome, absolute risk reduction is greater for those with diabetes, according to a study published online July 1 in The Lancet Diabetes & Endocrinology.

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Practitioner Empathy Has Lasting Benefit After T2DM Diagnosis

MONDAY, July 15, 2019 (HealthDay News) — Positive patient experiences of practitioner empathy in the year after type 2 diabetes diagnosis can confer long-term benefit, according to a study published in the July/August issue of the Annals of Family Medicine.

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Many Perceive Lack of Choice in Receipt of RAI for Thyroid Cancer

MONDAY, July 15, 2019 (HealthDay News) — Many patients diagnosed with differentiated thyroid cancer perceive that they have no choice about receiving radioactive iodine (RAI), according to a study published online July 8 in the Journal of Clinical Oncology.

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Opioids Commonly Prescribed in Emergency Department for Gout

MONDAY, July 15, 2019 (HealthDay News) — More than one-fourth of patients with acute gout discharged from the emergency department receive an opioid prescription, according to a study published online July 2 in Arthritis Care & Research.

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Tool Uses Spine X-Rays to Assess Response to Osteoporosis Tx

MONDAY, July 15, 2019 (HealthDay News) — A new measure derived from conventional X-rays and a machine learning algorithm is effective for assessing bone-specific effects of osteoporosis treatment, according to a pilot study published in the July issue of Skeletal Radiology.

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Risk for Leg Amputation Higher With Microvascular Disease

FRIDAY, July 12, 2019 (HealthDay News) — Microvascular disease (MVD) increases the risk for amputation alone and in combination with peripheral artery disease (PAD), according to a study published online July 8 in Circulation.

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Erectile Dysfunction Presents Large Global Health Burden

FRIDAY, July 12, 2019 (HealthDay News) — Erectile dysfunction (ED) is a large global burden and is associated with increased risks for cardiovascular disease, dementia, and early death, according to a review published online July 2 in BJU International.

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Serious Misdiagnosis-Related Harms Mostly Due to ‘Big Three’

FRIDAY, July 12, 2019 (HealthDay News) — Vascular events, infections, and cancers account for about three-quarters of serious misdiagnosis-related harms, according to a study published online July 11 in Diagnosis.

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Medicare Drug Rebate Plan Withdrawn by Trump Administration

THURSDAY, July 11, 2019 (HealthDay News) — A plan to let Medicare patients receive rebates that drug companies currently pay to insurers and middlemen has been withdrawn by the Trump administration.

AP News Article

Capping Work Hours in Residency Does Not Impact Outcomes Later

THURSDAY, July 11, 2019 (HealthDay News) — Exposure of U.S. physicians to work-hour reforms during residency training is not associated with post-training differences in patient mortality, readmissions, or costs of care, according to a study published online July 11 in The BMJ.

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Uncontrolled Diabetes, Hypertension Rates High in CKD Patients

THURSDAY, July 11, 2019 (HealthDay News) — For patients with chronic kidney disease (CKD), the prevalence of uncontrolled hypertension and diabetes is high and has not improved over time, according to a study published online July 11 in the Clinical Journal of the American Society of Nephrology.

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Health Care Professionals Exhibit Gender Bias

THURSDAY, July 11, 2019 (HealthDay News) — Survey results show that health care professionals have implicit and explicit gender bias, according to a study published online July 5 in JAMA Network Open.

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Rule Requiring Drug Prices in TV Ads Blocked by Judge

TUESDAY, July 9, 2019 (HealthDay News) — A Trump administration rule to force pharmaceutical companies to disclose the list prices of their drugs in television ads was blocked Monday by a federal judge.

The New York Times Article

EHR System-Generated In-Basket Messages Linked to Burnout

TUESDAY, July 9, 2019 (HealthDay News) — Receipt of more than the average number of electronic health record (EHR) system-generated in-basket messages is associated with an increased probability of physician burnout, according to a study published in the July 1 issue of Health Affairs.

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Environment May Be Main Factor in Norway’s Obesity Epidemic

TUESDAY, July 9, 2019 (HealthDay News) — Environment most likely remains the main contributor to the obesity epidemic in Norway, given that body mass index (BMI) has increased for both genetically predisposed and nonpredisposed people since the 1960s, according to a study published online July 3 in The BMJ.

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Food Insecurity Associated With Increased Insulin Resistance

TUESDAY, July 9, 2019 (HealthDay News) — Household food insecurity (HFI) is associated with insulin resistance among Latinos with type 2 diabetes, according to a study published in the June issue of the Journal of Nutrition.

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Consistent Time of Day Aids Workout Habit

MONDAY, July 8, 2019 (HealthDay News) — Consistency in timing of workouts may help sustain high physical activity levels among adults successfully maintaining weight loss, according to a study published online July 3 in Obesity.

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Treating Depression May Reduce Mortality in Diabetes Patients

MONDAY, July 8, 2019 (HealthDay News) — The use of most types of antidepressants (ATDs) is associated with significantly reduced mortality among patients with diabetes mellitus (DM) and comorbid depression, according to a study published online July 2 in the Journal of Clinical Endocrinology & Metabolism.

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Neurofilament Light Chain Levels Predict Stroke Risk in Diabetes

WEDNESDAY, July 3, 2019 (HealthDay News) — Serum neurofilament light chain (NfL) levels can predict incident stroke among middle-aged and older adults with diabetes mellitus, according to a study published in the July issue of Stroke.

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Considerable Number of Patients Receive Surprise Hospital Charges

TUESDAY, July 2, 2019 (HealthDay News) — Eighteen percent of all emergency department visits and 16 percent of in-network hospital stays have at least one out-of-network charge, according to a report published June 20 by the Kaiser Family Foundation.

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I-131 Tx for Hyperthyroidism May Up Risk for Solid Cancer Death

TUESDAY, July 2, 2019 (HealthDay News) — For patients with hyperthyroidism treated with radioactive iodine (RAI), greater organ-absorbed doses seem to be positively associated with increased risk of death from solid cancer, according to a study published online July 1 in JAMA Internal Medicine.

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Statin Use Associated With Higher Incidence of Diabetes

TUESDAY, July 2, 2019 (HealthDay News) — There may be a dose-dependent relationship between statin therapy and new-onset diabetes across the duration of statin use, according to a study recently published in Diabetes Metabolism Research and Reviews.

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Guide Addresses Medical Issues Relevant to Transgender Persons

TUESDAY, July 2, 2019 (HealthDay News) — A guide to help clinicians understand the medical issues relevant to transgender persons, based on a review of current evidence, was published online July 2 in the Annals of Internal Medicine.

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Guidance Issued for Management of Fontan Circulation

TUESDAY, July 2, 2019 (HealthDay News) — A scientific statement with recommendations for follow-up care in patients with Fontan circulation surviving into adulthood was published online July 1 in Circulation.

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Metformin May Cut Mortality Risk in Post-Pancreatitis Diabetes

MONDAY, July 1, 2019 (HealthDay News) — Metformin use may promote a survival benefit in individuals with post-pancreatitis diabetes mellitus (PPDM), but not pancreatic cancer-related diabetes (PCRD), according to a study published online June 21 in Diabetes Care.

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Romosozumab Increases Bone Formation, Cuts Bone Resorption

MONDAY, July 1, 2019 (HealthDay News) — For postmenopausal women with osteoporosis, romosozumab increases bone formation and decreases bone resorption, according to a study published online June 24 in the Journal of Bone and Mineral Research.

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