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Irregular Sleep Duration and Timing Linked to CVD Risk

Risk for cardiovascular disease increased in multivariable-adjusted models

TUESDAY, March 3, 2020 (HealthDay News) — Irregular sleep duration and timing are associated with an increased risk for cardiovascular disease (CVD), according to a study published in the March 10 issue of the Journal of the American College of Cardiology.

Tianyi Huang, Sc.D., from Brigham and Women’s Hospital in Boston, and colleagues examined the association between sleep regularity and risk for CVD in 1,992 participants free of CVD who completed seven-day wrist actigraphy for sleep assessment between 2010 and 2013. Participants were followed through 2016 for incident CVD, including nonfatal and fatal cardiovascular events.

The researchers found that 111 patients developed CVD events during a median follow-up of 4.9 years. Across categories of irregular sleep duration, the multivariable-adjusted hazard ratios (95 percent confidence intervals) were 1.00 for those with a difference of ≤60 minutes (reference) in sleep duration each night, 1.09 (0.62 to 1.92) for those with a difference of 61 to 90 minutes in sleep duration, 1.59 (0.91 to 2.76) for those with a difference of 91 to 120 minutes, and 2.14 (1.24 to 3.68) for those with a difference of >120 minutes (P trend = 0.002). Across categories of sleep timing, the hazard ratios for CVD were 1.16 (0.64 to 2.13) for a difference in sleep timing of 31 to 60 minutes, 1.52 (0.81 to 2.88) for a difference of 61 to 90 minutes, and 2.11 (1.13 to 3.91) for a difference of >90 minutes compared with a difference of ≤30 minutes (P trend = 0.002).

“Sleep regularity is a modifiable behavior,” Huang said in a statement. “In the future, we’d like to explore whether changing one’s sleep patterns by going to bed consistently each night may reduce a person’s risk of future cardiovascular events.”

One author disclosed financial ties to the pharmaceutical and medical device industry.

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