HRQoL Scores Decrease With Treatment Line in Multiple Myeloma

Relatively high scores seen for patients with multiple myeloma in first treatment-free interval

Drug Company Payments Over Time May Influence Rx Practices

Payment consistency, high amount, compensation payments tied to cancer drug prescribing practices

Midlife Systemic Inflammation Linked to Later Cognitive Decline

Individuals with a midlife inflammation composite score in top quartile had 7.8 percent steeper decline

Improved Outcomes Seen With Liver Grafts From Older Donors

However, liver graft discard from older donors remained increased from 2003 to 2016

FDA Panel Backs Ketamine-Like Drug for Depression

Esketamine is a nasal spray that targets different pathways in the brain than other antidepressants do

Autologous Stem Cell Transplant May Aid Some With Nodal PTCL

Prospective cohort study suggests benefit of ASCT for some with nodal peripheral T-cell lymphoma

Functional MRI Patterns Indicate Consciousness, Unconsciousness

Brains of unresponsive patients mainly have pattern of low interareal phase coherence

ASA: Opioid Epidemic Tied to Infection-Related Stroke

Number of hospitalizations steady in 1993 to 2008, but increased significantly in 2008 to 2015

Financial Hardship From Medical Bills Common in ASCVD

Uninsured, low-income adults have highest burden of financial hardship from medical bills

Fractures Have Long-Term Impact on Quality of Life for Older Adults

Hip, spine fragility fractures tied to negative impact on mobility, self-care, ambulation

CDC: Screening Policies for Critical Congenital Heart Dz Widespread

All 50 states, D.C. have implemented screening policies; data collection efforts have lagged

ASA: Intensive BP Control Lowers Bleeding Risk in Stroke Patients

Findings seen among patients with ischemic stroke, high systolic BP receiving alteplase for thrombolysis

Aspirin Underused for Advanced Colorectal Polyps

Only 42.6 percent of 84 patients with biopsy-proven advanced colorectal polyps were taking aspirin

Use of Watchful Waiting Up for Low-Risk Localized Prostate Cancer

From 2010 to 2015, use of active surveillance/watchful waiting increased in low-risk disease

Many Systematic Reviews Do Not Fully Report Adverse Events

Of 146 protocols analyzed, 65 percent fully reported adverse events as intended by the protocol

Acne Relapses Linked to Lower Quality of Life, Productivity

Relapse reported to be a significant determinant of productivity loss and absenteeism

Direct-Acting Antivirals Cut Mortality in Chronic Hepatitis C

Mortality, hepatocellular carcinoma risk reduced after adjustment for potential confounders

Larger Physician Bonus May Improve Care in Chronic Disease

No further improvement seen with behavioral economic principles of increased social pressure, loss aversion

USPSTF Recommends Counseling to Prevent Perinatal Depression

Clinicians should provide counseling or referral to high-risk pregnant, postpartum women

American Stroke Association, Feb. 6-8

The American Heart Association International Stroke Conference 2019 The annual International Stroke Conference of the American Heart Association/American Stroke Association (AHA/ASA) was held from Feb....

CDC: Student Tobacco Use Increased From 2017 to 2018

E-cigarette use up 77.8 percent among high school students, 48.5 percent among middle schoolers

Health Care Spending Per Person Increased to $5,641 in 2017

Spending per person increased 4.2 percent from 2016 to 2017; utilization increased 0.5 percent

Smaller Germinal Centers Identified in Recurrent Tonsillitis

Group A Streptococcus-specific CD4+ germinal center T follicular helper cells underrepresented

Women Less Likely to Get Periop Care Before Hip Fracture Surgery

Women also less likely to receive anesthesia consultation, more likely to have timely surgery

Children With Autism More Often Have Sleep Problems

More children with autism spectrum disorder have sleep problems compared with peers

Higher Optimism Tied to Lower Odds of Pain After Deployment

Soldiers with low optimism had increased odds of reporting new back pain, joint pain, headaches

More Than a Half Million Deaths From Breast Cancer Averted

Percent of breast cancer mortality reductions varied from 45.3 to 58.3 percent from 1989 to 2018

Reproductive Health Counseling Inadequate in IBD

Only 30 percent of patients reported prior counseling; most interested in receiving more information

Functional Decline Seen for Many Frail Patients After TAVR, SAVR

Older patients with severe frailty often have decline or lack of improvement after the procedures

Rates of Diabetes Screening High Among Adults Age ≥45

HbA1c used less frequently but results in more abnormal results, more diagnoses of prediabetes, diabetes

Simulation Captures Performance With Multifocal Intraocular Lens

Visual simulation captures individual optical, visual performance obtained with real M-IOLs

ASA: Reversal Agent Cuts Severe Bleeding With Factor Xa Inhibitors

Bolus plus two-hour infusion of andexanet alfa cuts antifactor Xa activity by 92 percent

Low Fitness, Obesity Linked to Later Disability Pension

Being moderately or highly fit as teen linked to lower risk for later receipt of disability pension in men

Many Children Not Receiving Needed Mental Health Treatment

About half of the 7.7 million children with at least one mental health disorder did not receive treatment

Racial/Ethnic, Income Variation ID’d in the Opioid Epidemic

Study, two research letters describe opioid prescribing trends and interactions with race, age

Congo Ebola Outbreak Claims Nearly 100 Children’s Lives

Number of new cases surged in January, from about 20 a week to more than 40

FDA Warns 17 Companies About Illegal Alzheimer Disease Products

The products are often sold on websites and social media and may be ineffective, unsafe

Johnson & Johnson to Provide Drug Prices in TV Ads

Drug list prices, typical out-of-pocket costs will appear on screen at end of commercials

Country-Specific Norms Created for Cancer-Related Quality of Life

New data from countries including the U.S. allow for intercountry, intracountry comparisons

Vaccine-Preventable Infections Common After Peds Transplant

These infections in organ transplant recipients associated with significant morbidity, mortality, costs

Education Not Tied to Rate of Cognitive Change in Seniors

Education was not associated with onset, rate of accelerated decline before dementia diagnosis

High-Risk HPV Infection Linked to Increased Risk for CVD in Women

High-risk HPV-CVD association stronger for those with obesity or metabolic syndrome

Delayed EMS Response Time Tied to Mortality After Car Accident

Longer emergency medical services response increases motor vehicle crash mortality in urban, rural settings

Certain Opioids Less Effective With SSRI Antidepressants

Surgical patients on SSRIs + prodrug opioids had higher postsurgical pain 8 weeks postdischarge

Slower Gait Speed, Shorter Step Length Tied to Later Depression

Slowest tertile for gait speed, shortest tertile for step length tied to higher likelihood of depression

Misuse of Rx Opioids Linked to Other High-Risk Behaviors

Prescribed opioid misuse strongly tied to other drug use disorders, illegal activity, psychological distress

CDC: Heart Attack Awareness Improved Since 2008

However, only about 50 percent of adults knew all five common heart attack symptoms in 2017

Diagnostic Delays Common in Inflammatory Bowel Disease

Overall, 68 percent of patients reported delay in diagnosis; delay more likely for UC versus Crohn disease

Predictors of Kidney Stone Recurrence Identified

Risk for recurrence within 5 years varies with risk factors, past episodes, time since last episode

Patient, Doctor Communication Priorities Differ in Ulcerative Colitis

Second study highlights importance of recognizing the emotional impact of ulcerative colitis

Walgreens Worst Violator in Tobacco Sales to Minors, FDA Says

Agency has requested meeting with Walgreen Co. to discuss possible companywide violations

Measles Outbreak Triggers Sharp Rise in Demand for Vaccine

More than 50 confirmed cases of measles, 11 suspected cases reported in Clark County, Washington, this year

Chronic Rhinosinusitis Linked to Depression, Anxiety

Higher hazard ratios found for depression, anxiety for patients with CRS without nasal polyps

FDA: Number of U.S. Women With Breast Implant-Caused Cancer Has Increased

Textured implants linked to cases of anaplastic large cell lymphoma

Postconditioning During PCI for STEMI Shows Delayed Benefits

Benefits at one year include reduced microvascular obstruction, improved left ventricular remodeling

Drug Combo Tolerated in Younger Children With Cystic Fibrosis

Lumacaftor/ivacaftor safe in children ages 2 to 5 with cystic fibrosis homozygous for F508del-CFTR

Trazodone Not Associated With Reduced Risk for Dementia

Study refutes animal studies suggesting trazodone delays dementia in patients at prodromal stage

Most Americans Concerned About Weight, Link to Heart Health

But many do not stick with weight-loss plans or talk with doctors about losing weight

Donor Heart Recovery From Drug-Intoxicated Deaths Has Increased

Campaigns promoting organ donation in populations affected by drugs have contributed to increase

T2DM Initially Remits in Majority Who Undergo Gastric Bypass

Roux-en-Y gastric bypass linked to significantly lower risk for microvascular complications

Shoulder Decompression Surgery Not Recommended

No important improvement seen in pain, function, quality of life versus placebo surgery, other options

Age-Standardized Mortality Rate for Suicide Down Since 1990

Age-standardized mortality rate higher for men than women; rate of decrease lower for men

Conservative Management Feasible for Adnexal Masses

Risk for malignancy, acute complications low for adnexal mass with benign ultrasound morphology

Discord Found in Clinician-, Criteria-Based Fibromyalgia Diagnosis

Physicians fail to ID half of criteria-positive patients, incorrectly ID 11 percent of criteria-negative patients

Parents Conflicted About Opioid Use in Children

Most parents know about alternatives to opioids, but just over a third ask about them

Many Children Not Following Toothbrushing Recommendations

Almost 80 percent start brushing later than recommended; 34.2 percent brush just once a day

Dialysis Staff-Initiated CPR Ups Outcomes in Cardiac Arrest

Staff-initiated CPR linked to increase in hospital discharge, favorable neurologic status on discharge

EEG-Guided Anesthesia Does Not Cut Postop Delirium in Seniors

Significantly less median cumulative time found with EEG suppression in EEG-guided group vs. usual care

Patient Tested for Ebola at Philadelphia Hospital

Testing was done out of 'an abundance of caution'

FDA Approves Cablivi for Rare Blood-Clotting Disorder

Drug approved to treat adults with acquired thrombotic thrombocytopenic purpura

Gastric Bypass May Aid Muscle Strength, Physical Performance

However, lean mass and absolute grip strength decline after surgery

Blood Type A2 to B Kidney Transplant Feasible

No difference in patient, graft survival; increased costs seen for A2 to B deceased donor kidney transplant

Hepatitis C Infection Rates Up After OxyContin Reformulation

222 percent increase in HCV infection rates seen after reformulation in states with above-median misuse

Antidepressant Overprescribing Appears Common in Elderly

Overprescribing tied to newer antidepressants, non-face-to-face interactions with prescribers

Psoriasis Tx Linked to Drop in Noncalcified Coronary Plaque

Noncalcified plaque burden and necrotic core reduced in association with biologic therapy

MRI-Guided Tx Strategy Not Superior for Rheumatoid Arthritis

No difference seen in proportion reaching primary end point versus conventional strategy

Hypertensive Crisis Prevalent in Urban African-Americans

Prevalence of hypertensive crisis is 11.4 percent in this population

ERAS Protocol Can Cut Opioid Use After Spine Surgery

Decline seen in postoperative opioid requirements after elective spinal, peripheral nerve surgery

Type 2 Diabetes Risk Up With PCOS Regardless of BMI

PCOS one of most influential predictors of T2DM after adjustment for BMI, education, family history

Value-Based Incentive Program Does Not Cut Catheter-Linked UTIs

VBIP implementation not linked with immediate changes or changes in trends for any outcome

Omadacycline Noninferior to Moxifloxacin for Pneumonia

Second study shows noninferiority to linezolid for acute bacterial skin and skin-structure infections

Recommendations Updated for Tonsillectomy in Children

Strong recommendations presented against administering perioperative antibiotics, codeine after tonsillectomy

Radiologists Can Help ID Intimate Partner Violence

IPV victims underwent more imaging studies in preceding five years than controls

Hemodialysis Facility Practices Linked to Patient Outcomes

Protocol that specifies how often to assess dry weight tied to lower all-cause, CVD mortality

Reading, Math Scores No Different for Children With T1DM

Estimated difference in test scores 0.45 after adjustment for variables such as socioeconomic status

California Bill Would Tighten Controls on Children’s Genitalia Surgery

Doctors who violate the proposed law could be disciplined by the state's medical board

8 Questions Helpful for Assessing IBD in Primary Care

CalproQuest survey may increase pretest probability for a positive calprotectin test

Ethnic Differences Seen at Time of Dementia Diagnosis in U.K.

Asian and black patients younger at diagnosis, have lower cognitive scores than white patients

Long-Term Opioid Use With OA Varies Across States

Variance not fully explained by differences in access to health care providers or patient characteristics

Compounded Topical Pain Creams No Better Than Placebo

At one month, no significant difference seen in positive outcomes for treatment vs. control

Evidence of Therapeutic Efficacy Substantial for Cannabis Use

Substantial, conclusive evidence of therapeutic efficacy found for 85.5 percent of qualifying conditions

AAP Releases 2019 Childhood Immunization Schedules

Influenza row modified to reflect current recommendations for live attenuated flu vaccine

No Increased Risk for Cancer for ART-Conceived Children

Slightly but not significantly increased risks seen in children conceived by ICSI or cryopreservation

Outcomes Good for Autologous Reconstruction After Implant Fail

Autologous breast reconstruction associated with improved patient satisfaction, quality of life

Burden of Sudden Cardiac Death Higher in Black Men, Women

Known factors explain 65.3 percent of excess SCD risk in African-Americans, especially women

Few Teens Meet Sleep, Exercise, Screen-Time Guidelines

Odds of meeting all three recommendations vary by age, race/ethnicity, BMI, marijuana use

USPSTF Still Recommends Against Pancreatic Cancer Screening

No evidence seen for benefits of pancreatic cancer screening, treatment of screen-detected cancer

Cancer Survivors Face Hardship Over Medical Bills

Hardships greatest among younger cancer survivors versus patients without cancer history

Updated ACIP Immunization Schedule Released for Adults

Changes recommended to influenza vaccine, hepatitis A and B vaccines

Early Tau Deposition Elevated for Women Versus Men

Clinically normal women exhibit higher entorhinal cortical tau, which is linked to higher Aβ burden

Expanded Recall of Warfarin Level Monitoring Test Strips

Inaccurate results may put patients at risk for serious injury or death

Washington State Measles Cases Now at 48 Since Jan. 1

Thirty-four cases involved children ages 1 to 10; 41 patients not vaccinated against measles

After Elbow Surgery, Children May Be Overprescribed Opioids

Patients who had supracondylar humerus fracture sx used less than 25 percent of prescribed drugs

Frailty Tied to Liver Transplant Wait-List Mortality in Cirrhosis

Cirrhosis patients with ascites or hepatic encephalopathy are more likely to experience frailty

High Physical Activity Levels Tied to Coronary Artery Calcification

But no increased mortality risk with high physical activity levels, CAC of ≥100 Agatston units

Tofacitinib Benefits Sustained for Two Years in Patients With RA

Safety, tolerability through 24 months was consistent with 12-month tofacitinib analysis

Unrestrained Driver Predicts Unrestrained Child Passenger

In crashes, unrestrained drivers have higher probability of having unrestrained young passengers

Severe Maternal Morbidity, Mortality Up With Infertility Tx

Likelihood of having three or more severe maternal morbidity indicators greater with invasive infertility tx

E-Cigarette Use Linked to Cigarette Initiation in Adolescents

Prior e-cigarette use tied to increased risk for cigarette initiation and use, especially for low-risk teens

CDC Examines Safety of Recombinant Zoster Vaccine

Total of 4,381 reports of adverse events during first eight months of use; 3 percent were serious

Sponge Cytology-Sampling Device Promising for Barrett Esophagus Dx

Swallowable sampling device combined with methylation biomarker panel IDs Barrett esophagus

Some Obesity-Related Cancers Increasing in Younger Adults

Incidence up for six of 12 obesity-related cancers; steeper increase in successively younger generations

January 2019 Briefing – Nursing

Here are what the editors at HealthDay consider to be the most important developments in Nursing for January 2019. This roundup includes the latest...

January 2019 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for January 2019. This roundup includes the latest...

CDC: Most Black HIV Patients Interviewed for Partner Services

78 percent of partners identified were notified of potential exposure; 47 percent were tested for HIV

January 2019 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for January 2019. This roundup...

January 2019 Briefing – Radiology

Here are what the editors at HealthDay consider to be the most important developments in Radiology for January 2019. This roundup includes the latest...

Direct-to-Doctor Payments May Increase Opioid Prescribing

Prescribers receiving opioid-specific payments prescribed 8,784 more opioid daily doses per year

January 2019 Briefing – Hematology & Oncology

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for January 2019. This roundup includes...

January 2019 Briefing – Anesthesiology

Here are what the editors at HealthDay consider to be the most important developments in Anesthesiology for January 2019. This roundup includes the latest...

Discontinuing TNFi Before Gestational Week 20 Is Feasible

No clinically meaningful disease worsening among women with well-controlled RA, juvenile arthritis

January 2019 Briefing – Ophthalmology

Here are what the editors at HealthDay consider to be the most important developments in Ophthalmology for January 2019. This roundup includes the latest...

January 2019 Briefing – Cosmetic Surgery

Here are what the editors at HealthDay consider to be the most important developments in Cosmetic Surgery for January 2019. This roundup includes the...

Physician Burnout Tied to Ability to Address Social Needs

Risk for burnout lower in clinics with social worker, pharmacist on care team

January 2019 Briefing – Orthopedics

Here are what the editors at HealthDay consider to be the most important developments in Orthopedics for January 2019. This roundup includes the latest...

January 2019 Briefing – Geriatrics

Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for January 2019. This roundup includes the latest...

Most Students Receiving Spectacles Wear Them at Follow-Up

Poorer presenting visual acuity and improvement in visual acuity with correction predict spectacle wear

January 2019 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for January 2019. This roundup includes the latest...

January 2019 Briefing – Pain Management

Here are what the editors at HealthDay consider to be the most important developments in Pain Management for January 2019. This roundup includes the...

Shortage of Anxiety Drug Creates Alarm Among Patients, Doctors

Buspirone price has fallen so low that many manufacturers claim they cannot make a profit on it

January 2019 Briefing – Psychiatry

Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for January 2019. This roundup includes the latest...

January 2019 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for January 2019. This roundup includes the latest...

January 2019 Briefing – Allergy

Here are what the editors at HealthDay consider to be the most important developments in Allergy for January 2019. This roundup includes the latest...

January 2019 Briefing – Pulmonology

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for January 2019. This roundup includes the latest...

HPV Educational Video May Increase Vaccination Rates

Adolescents whose parents watched the video were three times more likely to be vaccinated

January 2019 Briefing – Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for January 2019. This roundup includes the latest...

January 2019 Briefing – Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for January 2019. This roundup includes the latest...

Use of Image Analysis to ID HER2 Status in Breast Cancer Outlined

Guideline addresses use of quantitative image analysis to interpret HER2 immunohistochemistry

January 2019 Briefing – Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for January 2019. This roundup includes the latest...

January 2019 Briefing – Surgery

Here are what the editors at HealthDay consider to be the most important developments in Surgery for January 2019. This roundup includes the latest...

Maternal Factors Predict Postpartum Depression Trajectory

Parity, education, baseline global functioning, depression severity predict chronic severe trajectory

January 2019 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for January 2019. This roundup includes...

January 2019 Briefing – Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for January 2019. This roundup includes the latest...

Minimal Benefit for Decision Aid About Prolonged Ventilation

Web-based decision aid does not improve prognostic concordance between surrogates and physicians

January 2019 Briefing – Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for January 2019. This roundup includes the...

January 2019 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for January 2019. This roundup includes the...

Maternal Glucose in Pregnancy Tied to Child’s Glucose Outcomes

Maternal fasting plasma glucose is positively associated with FPG and A1C in childhood

January 2019 Briefing – Gastroenterology

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for January 2019. This roundup includes the latest...

January 2019 Briefing – Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for January 2019. This roundup includes the...

Hearing Loss Linked to Subjective Cognitive Function Decline

Findings seen in older men; risk for SCF decline also up for men with severe hearing loss using hearing aids

January 2019 Briefing – HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for January 2019. This roundup includes...

January 2019 Briefing – Emergency Medicine

Here are what the editors at HealthDay consider to be the most important developments in Emergency Medicine for January 2019. This roundup includes the...

Longitudinal TNF Levels Mainly Stable With Adalimumab in RA

Early low TNF strongly associated with formation of antidrug antibodies, may predict nonresponse

January 2019 Briefing – Infectious Disease

Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for January 2019. This roundup includes the...

January 2019 Briefing – Otolaryngology

Here are what the editors at HealthDay consider to be the most important developments in Otolaryngology for January 2019. This roundup includes the latest...

Pharmacist-Led Phone Follow-Up May Cut Readmission Rates

Intervention for polypharmacy patients linked to improved readmission rates, time to readmission

January 2019 Briefing – Neurology

Here are what the editors at HealthDay consider to be the most important developments in Neurology for January 2019. This roundup includes the latest...

January 2019 Briefing – Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for January 2019. This roundup includes the latest...

Mindfulness-Based Stress Reduction Also Benefits Chronic Pain

Compared with control, relative advantages seen for MBSR, cognitive behavioral therapy

E-Cigarettes More Effective for Smoking Cessation

One-year abstinence higher with e-cigarettes than other nicotine replacement products

Small Increase in HbA1c Seen With Switch to Human Insulin in T2DM

No increase in serious hypoglycemia, hyperglycemia after switch from analogue to human insulin

Long-Term Incidence of A-Fib Increased in Women With Breast Cancer

Women younger than 60 years have increased short-term, longer-term risk

Rising Temps May Up Burden of Congenital Heart Disease in U.S.

Large increases in specific congenital heart defect subtypes projected in different regions

Fruit, Vegetable Intake Very Low in Hemodialysis Population

Higher consumption of fruit and vegetables linked to lower risk for all-cause, non-CVD mortality

AHA: Nearly Half of U.S. Adults Have Cardiovascular Disease

Forty-six percent of U.S. adults have hypertension

FDA Approves First Generic Version of Advair for Asthma, COPD

Medication approved to treat children aged 4 or older with asthma, adults with asthma or COPD

Liver Transplant Wait List May Not Prioritize High-Risk Patients

Patients with ACLF-3 with a MELD-Na score less than 25 may benefit from prioritization

More High-Value Care Associated With Receipt of Primary Care

Increasing investment in primary care may improve value in the U.S. health care system

Oral Antibiotics Noninferior to IV for Bone, Joint Infection

Noninferiority in intention-to-treat analysis; supported by complete-case, per-protocol, sensitivity analysis

Symptom Combos Suggesting Laryngeal Cancer Identified

10 features of laryngeal cancer with which patients presented in year before diagnosis identified

Meta-Analysis: Small Weight Increase Seen for Breakfast Eaters

Total daily energy intake higher for participants who eat breakfast, but results inconsistent

Medical Scribes Up Productivity for Emergency Medicine Doctors

Primary consultations/hour increased, median length of stay reduced with use of scribes

Management of MS in Pregnancy Reviewed in U.K. Guideline

Pros and cons of continuing treatment throughout pregnancy should be discussed individually

Methotrexate Well Tolerated, Effective for Psoriasis in Chinese

Greater therapeutic response, fewer adverse events seen in those without psoriatic arthritis

Hand Hygiene Compliance Low Among EMS Providers

Use of hand rub or hand wash seen in 3 percent before, 29 percent after patient encounters

ASA: Increased Odds of Stroke, MI With E-Cigarette Use

E-cigarettes linked to increased odds of stroke, myocardial infarction, angina or coronary heart disease

ASA: Flu-Like Illness Linked to Increased Risk for Stroke

Second study shows patients more likely to have ILI within 30 days preceding cervical artery dissection

Infective Endocarditis Related to Injection Drug Use Rising

Rise in admissions for infective endocarditis tied to injection drugs paralleled rise in hydromorphone rx

FDA Receives an ‘F’ in Tobacco Prevention Report Card

American Lung Association releases State of Tobacco Control 2019 report

Aerobic Exercise Tied to Better Cognition at All Ages

Effect seen as young as 20 years, although the effect is greater with increasing age

Death at 10 Years Similar With Bilateral-, Single-Artery CABG

No difference seen in rate of death from any cause at 10 years in intention-to-treat analysis

Expanded Recall Announced for Ibuprofen Oral Suspension Drops

Higher levels of ibuprofen concentration found in some units may cause harm to infants

Undisturbed Maternal Sleep Tied to Higher Risk for Late Stillbirth

Maternal sleep patterns have been overlooked as indicators of maternal, newborn health

Off-Label Uses in Dermatology Often Missing From Compendia

Only 30.7 percent of 238 treatments used to treat 22 dermatologic conditions listed in compendia

No Asthma Benefit Seen With n3PUFA in Overweight Teens

Overweight/obese teens, young adults taking supplements do not have improved asthma control

Avoiding Full-Blown Diabetes Cuts Cardiovascular Risk

Early detection of prediabetes may reduce risk for developing cardiovascular disease

Patient Attitude Tied to Physical Therapy Outcomes

In patients with shoulder pain, self-efficacy, patient expectation linked to pain and disability outcomes

More Severe Injuries Sustained at Jump Parks Versus Home Trampolines

Proportion of fractures/dislocations, lower-extremity fractures, fractures in adults higher at jump parks

Thymectomy + PDN Beneficial for Non-Thymomatous Myasthenia Gravis

Thymectomy plus prednisone confers benefit versus prednisone alone at 5 years in myasthenia gravis

Public Health Interventions Could Cut Global Burden of Hepatitis C

Package of prevention, screening, treatments could avert 15.1 million new infections versus 2015

Finasteride Not Tied to Increase in Prostate Cancer Mortality

Finasteride tied to lower risk for death from prostate cancer, but lower risk not statistically significant

Few Patients With Type 1 Diabetes Meeting HbA1c Goals

Glycemic control not better in 2010 to 2018, despite more use of insulin pumps, continuous monitoring

Blood Conservation Safe, Effective During Heart Surgery

Intraoperative autologous donation strategy leads to improved outcomes

9/11 Responders May Have Higher Head, Neck Cancer Risk

Authors call for ongoing monitoring, treatment of those initially exposed

1976 to 2016 Saw Drop in Firearm Ownership in Families

However, proportion of white families who have young children and own handguns increased

Prophylaxis for Gonococcal Eye Infections in Newborns Advised

USPSTF reaffirms use of antibiotic ointment to prevent gonococcal ophthalmia neonatorum

Benefits, Barriers to Exercise Examined for Patients With ESKD

Patients undergoing dialysis would like to be able to exercise to improve energy, strength

Large Insulin Price Hike to Be Investigated by U.S. Congress

Currently, there is no effective generic alternative to brand-name insulin

New Guidelines Introduced for Inflammatory Bowel Disease in Pregnancy

Guidance explains best practices for managing patients across continuum of care and pregnancy

MEESSI-Acute Heart Failure Risk Score Validated

MEESSI-AHF has excellent discrimination for predicting 30-day mortality with c-statistic of 0.80