Group, Telephone, Guided CBT Treatment Effective for Depression

Individual and group CBT were significantly better than guided self-help in terms of acceptability

Increased Screen Time in Preschool Tied to Worse Inattention

Odds increased for reporting clinically significant externalizing problems, inattention problems

Atrasentan Tied to Lower Risk for Kidney Events in T2DM With CKD

Reduced risk seen for primary composite renal end point event; more frequent fluid retention, anemia reported

Statins Safe, Effective in Rheumatoid Arthritis Patients

However, cardiovascular event rates are low, do not require a primary prevention strategy for all patients

Informational Film Improves Knowledge on Lung Cancer Screening

Mean objective and subjective knowledge improved; higher decisional certainty seen with film

FDA Approves First Generic Nasal Spray Against Opioid Overdose

Product is also first generic naloxone nasal spray approved for use by people without medical training

Naltrexone Implant Helps HIV Patients Prevent Opioid Relapse

Compared with oral naltrexone, implant also improved HIV outcomes among those with opioid dependence

Loan Forgiveness, Educational Debt May Affect Practice Patterns

Graduates with loan forgiveness/repayment program more likely to enter primary care fields

Short Hospital Stays After Lung Surgery Do Not Up Readmissions

Findings based on one- to two-day length of stay versus three to five days after anatomic lung resection

Conception by IVF May Increase Risk for Rare Childhood Cancer

Rate of hepatic tumors higher among children conceived via IVF

Acetaminophen Safe as First-Line Analgesic for Most Older Adults

But there may be a higher stroke risk in elderly patients with diabetes taking the drug

Elevated Blood Lead Levels Prevalent Among Refugee Children

Correlations seen for EBLL with younger age, male sex, and overseas examination country

Risk for T2DM Increased With Use of 5α-Reductase Inhibitors

Increased risk seen among men using dutasteride, finasteride for benign prostatic hyperplasia

Need for Sedation Up for Regular Cannabis Users

Regular cannabis users undergoing endoscopic procedures need higher dose than nonusers

Late-Pregnancy US Could Prevent Undiagnosed Breech Presentation

Universal ultrasound at 36 weeks in nulliparous women would ID thousands of undetected cases

Stimulation of Targets in Brain May Up Recollection in Seniors

Effects of stimulation were greater on fMRI recollection signals versus recognition signals

Sensory Sensitivity Tied to Constipation in Young Children

Feeding problems due to sensory sensitivities common in children with constipation

Interns Spend Most of Their Time in Indirect Patient Care

Within a 24-hour period, interns spend a mean of 3.0 hours in direct patient care and 1.8 hours in education

Anti-Inflammatory Add-On May Be Beneficial for Depression

Anti-inflammatory agents improve depressive symptoms versus placebo as add-on in MDD

Trial Results Unclear for Benefit of Longer Hemodialysis Sessions

Intervention uptake not sufficient to assess impact of longer hemodialysis sessions on patient outcomes

CDC: Recent Decline Seen in High-Grade Cervical Lesions

Vast majority of cervical precancer cases attributable to HPV types targeted by 9-valent HPV vaccine

Sixty People Charged in Massive Opioid Painkiller Investigation

Individuals linked to about 350,000 prescriptions and 32 million pills

Perinatal Complications Tied to Childhood Social Anxiety

Perinatal birth complications associated with childhood social anxiety symptoms and behavioral inhibition

Infections May Up Risk for Developing Sjögren Syndrome

Lung, skin, urogenital infections tied to increased risk for developing primary Sjögren syndrome

Public Disclosure Law Improves Nurse Staffing Ratios

After enactment of N.J. law mandating reporting of staffing info, patients per RN fell for 10 specialties

UB-421 Monotherapy Maintains HIV Viral Suppression

Suppression maintained for up to 16 weeks in HIV-infected undergoing analytic treatment interruption

Machine Learning IDs Risk for Familial Hypercholesterolemia

Classifier developed using EHR data identifies patients at highest probability threshold for FH

Digital Replantation Seems Better Than Revision Amputation

Replantation recommended when three or more digits amputated, for distal single-finger amputation

Surgical Site Infection Rates May Differ by Gender

SSI rates differ by gender for certain procedures, including increased risk for women after heart surgery

Sleep Myths Are Commonly Circulated

Authors say initiatives to debunk myths, promote healthful sleep practices may benefit public health

Hand Hygiene Compliance Poor in Task Transitions

Hand hygiene compliance was 50.8 percent when health care workers moved from dirtier to cleaner tasks

Microbial Features ID’d for Pediatric Irritable Bowel Syndrome

Microbial and metabolic features can differentiate preadolescent children with IBS from controls

Abnormal Romberg Test Predicts Prolonged Concussion in Children

Abnormal performance independently associated with longer duration of symptoms for children

More Sports Experience May Reduce Impact of Concussions

Among youth with concussion history, more years of experience tied to quicker functional recovery

More Than Half of Internal Medicine Graduates Choosing Primary Care

Programs with a majority of graduates entering primary care less likely to have X+Y scheduling

Most Diabetes Phone Apps Lack Education, Support Functions

Most apps do not trigger alert escalation with consecutive low or high blood glucose values

Some Patients With Imminently Fatal Cancer Undergo Treatment

Variation seen in treatment by cancer type, age, insurance, and facility type

CDC: Raw Tuna Linked to Salmonella Outbreak in Seven States

Raw ground tuna supplied by Jensen Tuna is likely source of outbreak

Parenteral Antimicrobial Tx at Home Burdens Children’s Caregivers

Compared with those who receive oral therapy, caregivers miss more work, have lower QoL scores

Stroke Hospitalizations Down in Black, White Medicare Enrollees

Black men and women have experienced greater improvements in 30-day poststroke mortality

AI Can Identify Model of Cardiac Rhythm Device From Chest X-Ray

Neural network's performance significantly exceeds ability of cardiologists

iADL Dependency May Up Mortality in Hematologic Cancers

Instrumental activities of daily living dependency, mortality linked in seniors with hematologic cancer

About One-Quarter of Seniors Store Firearms Unlocked, Loaded

No difference seen in prevalence of mental distress, memory loss by household firearm ownership, storage

One in Three U.S. Adults Aged 35 to 44 May Have Drinking Problem

Nine percent continue to drink despite negative effects on career, education, relationships

Low Scam Awareness May Indicate Alzheimer Risk in Seniors

Increased risk for Alzheimer dementia, mild cognitive impairment seen with low scam awareness in seniors

Reasons for TKI Discontinuation ID’d in Chronic Myeloid Leukemia

Treatment-free remission maintained in 14 of 21 patients who discontinued tyrosine kinase inhibitors

ACP: Half of Practices Implement Telehealth Technology

However, to address the gap in actual usage, the American College of Physicians will develop resources

Low-Carb Breakfast May Improve All-Day Glucose Control in T2DM

In addition, high-fat, low-carb breakfast tied to less hunger later in the day

Over Half of Patients Have Suboptimal Response to Statins

Suboptimal responders have increased risk for incident cardiovascular disease

Intensive BP Lowering May Up Cognitive Decline in Elderly

For those on antihypertensive treatment, cognitive decline greater with SBP <130 versus >150 mm Hg

Mixed Effects Observed for Workplace Wellness Program

Improvement seen in some self-reported health behaviors but not clinical health markers, health care utilization

USPSTF: Evidence Lacking for Elevated Lead Level Screening

Evidence inadequate to determine benefits, harms of screening for asymptomatic children, pregnant women

American College of Physicians, April 11-13

The American College of Physicians Internal Medicine Meeting 2019 The annual meeting of the American College of Physicians (ACP) was held from April 11 to...

FDA Halts All Sales of Pelvic Mesh Products Tied to Injuries in Women

Remaining manufacturers have failed to prove the long-term safety or benefit of their devices

Trigeminal Nerve Stimulation Beats Sham Tx for Peds ADHD

Improvement observed in 8- to 12-year-olds with no clinically meaningful adverse events

Barriers to Opioid Use Disorder Treatment Should Be Addressed

Report IDs barriers such as separation of OUD treatment delivery settings from rest of medical care

Replacing 30 Minutes of Sitting With Activity May Cut Mortality

Link most strong among least active adults; no association seen among most active adults

Cognitive Behavioral Therapy Effective for Prenatal Insomnia

Women in CBT group had greater reductions in insomnia severity, were likely to have remission

More Than 80 Percent of STEMI Patients Treated in ICU

However, only 16.2 percent of patients develop complications requiring ICU care while hospitalized

New Scale Helps Identify More Serious Cases of Mononucleosis

Scale identifies college students at increased risk for corticosteroid Rx, chronic fatigue syndrome

Skin Diseases Appear to Be Underdiagnosed

Majority of affected participants in a random sample in Germany were unaware of their conditions

Metformin May Cut Risk for Prematurity, Miscarriage in PCOS

But no significant differences seen in gestational DM risk between metformin users, nonusers

Gestational Diabetes Linked to Incident Diabetes in Offspring

Risk for developing pediatric diabetes increased in offspring from birth through age 22 years

Added Sugar Labeling Could Reduce CVD, Diabetes Cases

Labeling would result in gain in quality-adjusted life-years and health care and societal cost savings

Colorectal Neoplasia Risk Up for Hodgkin Lymphoma Survivors

Prevalence higher for advanced adenomas, advanced serrated lesions, serrated polyposis syndrome

Standardizing Demographics Ups Accuracy of Patient Matching

Standardization of address and last name improved sensitivity from 81.3 to 91.6 percent

Canagliflozin Seems Effective for Patients With T2DM, Kidney Disease

Reductions seen in risk for kidney failure, cardiovascular disease with canagliflozin versus placebo

WHO: Congo Ebola Outbreak Still Not a Global Emergency

Outbreak, which began on Aug. 1, 2018, is second deadliest in history

Terminally Ill People in New Jersey Given Right to End Lives

New law allows adults with a prognosis of six months or less to live to get a prescription for life-ending pills

CDC: 555 Confirmed Measles Cases in U.S. Since Jan. 1

20 states have reported measles cases

Normalizing BP in Elderly With Hypertension May Up Mortality

Blood pressure values less than 140/90 mm Hg tied to increased mortality risk for octogenarians

Telehealth Video Visits Risk Fragmenting Care

Users of video visits are less likely to have a primary care source of care

Female Radiation Oncologists Receive Lower Medicare Reimbursement

Compared with male counterparts, they submit fewer charges and are reimbursed less

AEDs Tied to Higher Pneumonia Risk in Alzheimer Patients

Risk for pneumonia highest within first month of antiepileptic drug use but persists through two years

Fibrosis, Steatosis of the Liver Observed in Some Young Adults

Within Avon Longitudinal Study cohort, 2.4 percent of young adults had fibrosis; 20.8 percent had steatosis

Operator-Directed Sedation Seems Safe in Peds Cardiac Cath

ODS is not associated with increased risk for adverse events among carefully selected patients

In Pregnancy, Buprenorphine Use Up, Methadone Use Down

And the 4Ps Plus and SURP-P scale are sensitive for identifying illicit drug use in pregnancy

Pruritus Prevalent and Disruptive in Nondialysis Chronic Kidney Disease

Patients with pruritus have higher prevalence of patient-reported depression, restless sleep

CDC Clarifies Guideline on Opioid Prescribing for Chronic Pain

Clarification pertains to opioid prescribing for cancer patients, cancer survivors, sickle cell disease

Complementary, Alternative Medicine Use High in Cancer Patients

One-third of cancer patients, survivors use CAM; 29.3 percent do not disclose CAM use to their doctor

Prevalence of Extragenital STDs High in Men Who Have Sex With Men

Extragenital STDs mostly seen in throat and rectum, contribute to risk for drug-resistant gonorrhea and HIV

Pharmacy Practice Managers Report Frequent Drug Shortages

More than one-third of respondents reported no administrative methods for responding to shortages

ACR Issues Position Statements on Drug Pricing, Step Therapy

Statements emphasize need for safe, convenient, affordable access to rheumatology treatments

Daily Dose of Nature Cuts Stress Hormone Levels

Only 20 minutes of nature contact shows most efficient lowering of cortisol levels

Daily Cannabis Use More Common in Distressed Individuals

But use increasing among those with and without past-month serious psychological distress

FDA Approves Personalized Tx for Metastatic Bladder Cancer

Balversa indicated for treatment of bladder cancer with FGFR3 or FGFR2 genetic alteration

Morbidity Low With Focal Laser Ablation of Prostate Cancer

Tumor diameter above the median was only significant predictor for positive MRI after treatment

Foreign Body Ingestions Increasingly Common in Young Children

Annual rate increased significantly from 9.5 to 18 per 10,000 children from 1995 to 2015

Colchicine May Improve Obesity-Induced Inflammation

Pilot study did not show better insulin sensitivity but showed trend toward metabolic improvements

Cytomegalovirus Linked to Faster Progression of Cystic Fibrosis

Faster progression to end-stage lung disease observed among patients with CMV IgG positivity

Very Low LDL-C, Triglycerides Tied to Hemorrhagic Stroke Risk in Women

Women with very low LDL or triglycerides should be monitored for other modifiable stroke risk factors

Stress-Related Disorders Associated With Increased CVD Risk

Hazard ratios for cardiovascular diseases decreased beyond one year after disorder diagnosis

Presence of Leukemia Cutis Tied to Worse Survival in AML

Hazard ratios for leukemia-specific death, all-cause death higher for patients with AML and LC

Domestic Responsibilities Tied to Physician Mothers’ Satisfaction

Being responsible for at least five tasks linked to desire to change career for moms in procedural specialties

DLQI With ‘Not Relevant’ Answers May Underrate Psoriasis Severity

Objective, subjective disease severity worse for those responding 'not relevant' versus 'not at all'

Four Million New Peds Asthma Cases Attributed to NO2 Annually

Burden of new pediatric asthma cases accounts for 13 percent of global incidence

SSI Risk Up After C-Section for Medicaid Beneficiaries

Odds of surgical site infection increased for women covered by Medicaid versus private insurance

Mindfulness Yoga Aids Patients With Parkinson Disease

Effects similar to those of stretching and resistance training for motor dysfunction, mobility

Older Adults With Hearing Loss Have Lower Patient Activation

Even those with 'a little trouble' hearing have higher risk for low activation than those with 'no trouble'

Myoelectric Computer Interface Beneficial for Stroke Survivors

MyoCI well tolerated, can reduce abnormal coactivation in stroke survivors with arm impairment

CDC: Prevalence of Autism at Age 4 Years Increasing

Frequency of co-occurring intellectual disabilities higher among children aged 4 years than 8 years

CDC: Superbug Fungus Has Sickened 600 Americans

Candida auris can survive on surfaces after routine cleaning and is often drug-resistant

Inflammatory Arthritis Linked to Sexual Dysfunction

Themes of impaired sexual function, compromised intimate relationships ID'd in studies of IA patients

Nonalcoholic Fatty Liver Disease Burden Up Among HIV-Infected

NAFLD becoming increasingly important cause of liver disease, liver mortality

Recurrence Score May Cut Costs for High-Risk Breast Cancer Care

Testing with 21-gene assay linked to lower relative, absolute costs among high-risk patients

Haptoglobin Expression Tied to Outcomes in Preterm Newborns

Worse outcomes in preemies lacking haptoglobin who were exposed to inflammation in utero

Same Services More Expensive in Outpatient Than Office Settings

2009 to 2017 also saw increase in proportion of services performed in outpatient settings

STI Incidence Up After Receipt of HIV Preexposure Prophylaxis

Younger age, greater partner number, group sex, but not condom use, linked to increased risk of STI

People With Obesity Are Blatantly Dehumanized

Dehumanization predictive of support for policies that discriminate against people with obesity

Peripheral Nerve Block May Cut Opioid Use After Amputation

Peripheral nerve block helps improve pain control after major lower extremity amputation

Review Links Adverse Events to Use of Herbal Meds in Pregnancy

Increased odds of preterm birth with almond oil; oral raspberry leaf linked to cesarean delivery

2000 to 2015 Saw Increase in Liver Cancer Mortality

Increase generally steeper in less educated women; confined to men with ≤15 years education

Complication Rates Low for High-Volume Pediatric Thyroid Surgery

Low complication rates for surgical management of pediatric thyroid disease at high-volume center

Caregiving for Older Cancer Patients Takes Emotional Toll

Poorer patient health tied to higher levels of caregiver distress among informal caregivers

Verubecestat, Atabecestat Not Beneficial for Preventing Alzheimer Disease

Two trials show lack of effectiveness versus placebo for preclinical Alzheimer disease

CDC: Still No Source As E. Coli Outbreak Grows to 96 Cases

Outbreak affecting five states; no deaths reported, but 11 people have been hospitalized

FDA: Patients Should Not Abruptly Stop Taking a Prescribed Opioid

Agency warns that rapid discontinuation can result in uncontrolled pain or withdrawal symptoms

FDA Warns of Consumer Devices That Claim to Diagnose Concussion

Tools include smartphone apps marketed to coaches or parents for use during sporting events

Cardiac-Specific Comorbidity Index Beats Generic Indexes

Cardiac-specific index outperforms other indexes for predicting in-hospital mortality, length of stay

Cardiovascular Mortality Lower With Medicaid Expansion

Lower cardiovascular mortality rates seen for middle-aged adults in states that expanded Medicaid

High Response Seen for All Hep C Tx Models in Injection Drug Users

Directly observed therapy tied to greater adherence than self-administered individual treatment

Dietary Supplement Use Not Linked to Mortality Benefits

Excess calcium intake may increase risk for cancer death; link related to supplemental calcium intake

Continued Smoking Among Cancer Patients Ups Costs by $3.4B

Estimates based on additional treatment following higher failure risk for first-line cancer treatment

New, Revised Topics Released in ACR Appropriateness Criteria

New topics relate to clinically suspected vascular malformation of extremities, gestational trophoblastic disease

Functional Impairment in Middle Age Linked to Adverse Outcomes

Impairment in activities of daily living linked to increased risk for hospitalization, nursing home admission

More Secondary Prevention Meds May Reduce Deaths After AMI

Mortality lower with more meds for older nursing home residents after acute myocardial infarction

Suicide-Related ED Visits Increased in Children From 2007 to 2015

Proportion of emergency department visits increased for suicide attempts/suicide ideation

Chloroprocaine Offers Adequate Anesthesia for Knee Arthroscopy

Shorter time to complete recovery from motor blockade seen for chloroprocaine compared with prilocaine

Proximity to Major Roadways Impacts Child Development

Increased risk for child developmental delays also seen with prenatal exposure to PM2.5, ozone

Genetic Testing Underused in Breast, Ovarian Cancer

Pathogenic variants ID'd in 7.8 percent of patients with breast cancer, 14.5 percent with ovarian cancer

Cortical Lesions in Multiple Sclerosis Tracked With 7.0-T MRI

Development of cortical lesions surpassed that of white matter lesions, linked to neurologic disability

Many NPs Unable to Prescribe Meds to Treat Opioid Addiction

Greater practice restrictions lead to lower percentage of NPs with waivers to prescribe buprenorphine

CDC: Measles Cases Reach 465 This Year in the United States

Meanwhile, New York City declares public health emergency over measles outbreak in Brooklyn

FDA Approves Osteoporosis Tx for High-Risk Postmenopausal Women

Boxed warning states increased risks for cardiovascular death, stroke, heart attack

CDC: TB Incidence Declined Slightly in United States in 2017

Number of cases, disease incidence decreased globally, but more progress needed to meet targets

Preventive Drugs Often Used in Last Year of a Cancer Patient’s Life

Preventive drugs, including antihypertensives and statins, frequently continued until final month of life

Alcohol, Drug Misuse Tied to Long-Term Health Problems

Despite recovery, chronic physical disease continues to impact quality of life, life expectancy

Older Patients With Crohn Disease May Benefit From Early Combo Tx

Early step-up combo therapy includes tumor necrosis factor-α antagonist plus an antimetabolite

Seniors Less Likely to Receive or Have Timely PCI for Acute MI

Patients >65 years of age have increased incidence of cardiac arrest, in-hospital mortality

Telemedicine Leads to More Antibiotic Rx for Pediatric Respiratory Infection

More antibiotics prescribed with less guideline-concordant antibiotic management versus other settings

Model Can Predict Sepsis Risk for Emergency Medical Admissions

Computer-aided National Early Warning Score model makes use of data already collected by clinicians

Early T2DM Diagnosis Linked to Increased Cardiovascular Risk

Highest excess risk for mortality, CV mortality, heart failure, CHD seen for T2DM patients diagnosed before 40

Draft Recommendation Promotes Screening Women for Anxiety

Teen, adult women, including pregnant women, should be assessed for anxiety as part of routine care

Genetic Research Results May Warrant Updates to Participants

Participants should be recontacted in some cases of new information about variant, newly ID'd variants

Guidance Statements Issued for Breast Cancer Screening

Clinicians should discuss mammography with patients aged 40 to 49, discontinue screening for those ≥75

Variation ID’d in Rate of Sexual Onset Before 13 Among Boys

Likelihood of reporting sexual intercourse before 13 lower for boys whose mothers have college degree

Ten Infant Deaths Linked to Fisher-Price Rock ‘n Play Sleepers

All infants died after rolling from their back to their stomach or side while unrestrained

FDA Warns Against Use of Preowned or Unauthorized Test Strips

Unauthorized, preowned test strips could cause infection, inaccuracy

First Two-Drug Regimen Approved for HIV-1 Treatment

Dovato indicated for use in patients with no history of antiretroviral treatment

American Association for Cancer Research, March 29-April 3

The American Association for Cancer Research Annual Meeting The annual meeting of the American Association for Cancer Research was held from March 29 to April...

Calcium Intake Tied to Lower Rate of Late AMD

Patients encouraged to continue taking calcium if needed for other indications

No Benefit Seen With Rituximab for Chronic Fatigue Syndrome

B-cell depletion using several rituximab infusions over 12 months not linked to clinical improvement

Digital Breast Tomosynthesis Boosts Metrics in Older Women

DBT yielded lower abnormal interpretation rate, higher positive predictive value 1, higher specificity

Pregnancy History Not Likely Tied to Later Cognitive Function

Authors say childbearing decisions and timing have no long-term impact on cognitive function

Patient Behaviors Identified That Impact Weight Regain After RYGB

Independent links for sedentary time, eating fast food, eating when feeling full, eating continuously

Depressive Symptoms May Up Risk for Death in HIV+ Veterans

However, depression linked to higher risk for death in HIV-uninfected, but not HIV-infected, U.S. veterans

Topical Corticosteroids Associated With Higher Risk for Type 2 Diabetes

Dose-response relationship observed in large European cohort

CDC: Prevalence of COPD High Among Some Nonsmokers

High prevalence observed in certain industries and occupations, including information industry

Histologic Clearance of CIN2/3 Seen With HPV Therapeutic Vaccine

In phase II trial, rate of complete resolution of CIN2/3 significantly higher for vaccine versus placebo group

Ibrance Approval Expanded to Include Men With Breast Cancer

Kinase inhibitor approved in combination with endocrine therapy for male patients with breast cancer

October May Be Best Time for Older Adults to Receive Flu Shot

Waning protection with early vaccine must be balanced with fewer vaccinated with compressed schedule, early peak

Racial Disparities Persist in Revascularization for CHD

Rates of revascularization lower for black women with acute coronary syndrome, coronary heart disease

Health Issues Prevalent Across BMI Classes for Obese Children

Mental health issues consistent across BMI groups; social, mechanical issues more common with higher BMI

Female Infertility Specialists Make Less Than Male Specialists

Findings remain significant even when accounting for years in practice and type of practice

FDA: High Levels of Heavy Metals Found in Kratom Products

Products contain levels of lead and nickel at concentrations that exceed safe daily intake

FDA Issues Warning on E-Cigarette Liquids Resembling Cough Syrup

Products have labeling, advertising that imitate prescription cough syrup products

Computer Model Predicts Risk for Ventricular Arrhythmia in ARVC

Clinical benefit of model was superior to current consensus-based ICD placement algorithm

Patient-Report Instrument Helps Identify ADEs in Older Adults

With accuracy of 75 percent, tool differentiates between symptoms of adverse drug events, chronic disease

Neoadjuvant Chemotherapy Key to Survival in Pancreatic Cancer

Three factors independently linked to prolonged survival in BR/LA pancreatic ductal adenocarcinoma

11 Million Deaths Attributable to Poor Diet in 2017

Leading dietary risk factors for deaths, DALYs include high sodium intake, low intake of whole grains

Most Osteoporosis Guidelines Do Not Discuss Patient Choices

When patient beliefs, values, preferences are cited, they are not usually supported by evidence

Short Sleep Duration, Not OSA, Linked to Daytime Sleepiness

Obstructive sleep apnea, but not SSD, is linked to obesity, hypertension, and dyslipidemia

Odds of Hay Fever Up With Very Early, Late Spring Onset

Odds of hay fever increased for start of season more than three weeks before or after normal onset

Adherence to Prenatal Screening Recommendations Varies by Lab

Laboratories vary in the extent to which they meet ACMG position statement recommendations

Early Hospital Intervention for Diabetes Improves Outcomes

Early identification and management decreases hyperglycemia, hospital-acquired infections

Drop Seen in Preinvasive Cervical Disease With HPV Vaccination

Vaccine effectiveness increased for immunization at younger age

Readmission Risk Up With Shorter Stay at Nursing Facility

For patients with heart failure discharged to SNF then home, risk highest during first two days at home

State Texting-While-Driving Bans Cut Crash-Related ED Visits

Findings show laws curbing distracted driving are effective

Older Patients With Vision Loss Have Higher Hospital Use, Costs

Similar findings seen among patients with commercial insurance

CDC: Violence Against Seniors on Rise, Especially Among Men

Nonfatal assault rate increased 75.4 percent among men from 2002 to 2016

Heart, Lungs From Hep C-Infected Donor Can Be Transplanted Safely

Transplant into patients without HCV infection feasible, with excellent function at six months

FDA Reports Cases of Seizures Among Young Vapers

Agency review revealed 35 reported cases of seizures following use of e-cigarettes since 2010

Population Mortality Affects Long-Term Follow-Up of AlloHCT

Substantial part of total nonrelapse mortality for older patients due to population mortality

Late Preterm Steroid Therapy Found to Be Cost-Effective

Compared with no tx, costs lower when high-risk women given betamethasone in late preterm period

Beta Interferon Tied to Lower Mortality in Relapsing-Onset MS

Increased survival seen with more than three years of beta interferon exposure but not lower exposure

Many ICU Workers Contaminated With Drug-Resistant Bacteria

Improper removal of protective equipment tied to higher risk for drug-resistant organism contamination

Computer Model Predicts Risk for Ventricular Arrythmia in ARVC

Clinical benefit of model was superior to current consensus-based ICD placement algorithm

Bariatric Embolization Feasible for Treatment of Severe Obesity

Bariatric embolization results in weight loss for up to 12 months, increase in quality of life

AACR: HPV Vax Low for Adults at High Risk for HIV Infection

Age, sex, sexual orientation differences in HPV vaccination rates were statistically significant

Almost Three-Quarters of Allergists Have Prescribed SLIT

Main barrier to sublingual immunotherapy is limitation of treating only one allergen

Racial Disparities Seen in Kidney Transplant for Highly Sensitized

Whites have advantage in transplant probability in calculated plasma reactive antibody categories 80 percent or higher

New Plan Limits Out-of-Pocket Costs for Insulin

Rising costs of insulin causing patients to ration their doses or even do without the drug

Minerals Not Linked to Multiple Sclerosis Risk in Women

Associations null when women with highest versus lowest intake in quintiles, deciles compared

Inferior Facial Coverage Observed With SPF Moisturizer

Application of SPF moisturizer significantly worse than sunscreen, especially around eyelid regions

For TAVR, Inverse Link Identified for Hospital Volume, Mortality

Higher 30-day mortality in lowest- versus highest-volume quartile of transfemoral TAVR procedures

Amyloid PET Linked to Changes in Management for MCI, Dementia

Change in management between pre-, post-PET visits for 60.2 and 63.5 percent with MCI, dementia

U.S. Measles Cases Already Top Last Year’s Total

387 reported cases in 15 states as of March 28

Americans Borrowed $88 Billion in Past Year to Pay for Health Care

Many do not seek treatment for health issues due to cost or reduce spending to pay for health care

Over-the-Counter Meds Save Health Care System Money

OTC medicines lead to $146 billion in annual clinical and drug cost savings

Reduction in Autism Diagnoses Observed With DSM-5

Use of DSM-5 linked to reductions in diagnosis of ASD, DSM-IV-TR autistic disorder, Asperger