Cesarean Delivery May Up Risk for Severe Maternal Morbidity

C-section linked to higher risk, especially among women aged 35 years or older

Guidelines Address PFO Closure for Secondary Stroke Prevention

Institutional requirements, multidisciplinary collaboration, quality measures addressed

AACR: Pembrolizumab Beneficial for Advanced Small Cell Lung Cancer

Antitumor activity promising; objective response rate 19.3 percent for patients with incurable, advanced SCLC

Dolutegravir Feasible for HIV Tx in Women of Childbearing Age

Risk for neural tube defects offset by fewer deaths among women, decreased sexual HIV transmission

One Hour of Activity/Week Helps Maintain Disability-Free Status

Findings seen among adults aged ≥49 years at elevated disability risk due to lower-extremity joint symptoms

Sex Hormone Levels May Impact Development of Asthma

Genetic evidence shows elevated SHBG levels may protect against asthma, mostly in females

March 2019 Briefing – Nursing

Here are what the editors at HealthDay consider to be the most important developments in Nursing for March 2019. This roundup includes the latest...

March 2019 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for March 2019. This roundup includes the latest...

Liquid Meal Replacements Cut Cardiometabolic Risk Factors

Effects observed in overweight/obese patients with T2DM; certainty of evidence low to moderate

March 2019 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for March 2019. This roundup...

March 2019 Briefing – Radiology

Here are what the editors at HealthDay consider to be the most important developments in Radiology for March 2019. This roundup includes the latest...

AACR: Longer Survival With Gilteritinib in FLT3mut+ AML

Longer overall survival, better remission rates seen for patients receiving gilteritinib versus salvage chemo

March 2019 Briefing – Hematology & Oncology

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for March 2019. This roundup includes...

March 2019 Briefing – Anesthesiology

Here are what the editors at HealthDay consider to be the most important developments in Anesthesiology for March 2019. This roundup includes the latest...

Doctors Unclear on Legal Obligations in Caring for Patients With Disability

Doctors report having little formal training, have incorrect understanding of care for patients with disability

March 2019 Briefing – Ophthalmology

Here are what the editors at HealthDay consider to be the most important developments in Ophthalmology for March 2019. This roundup includes the latest...

March 2019 Briefing – Cosmetic Surgery

Here are what the editors at HealthDay consider to be the most important developments in Cosmetic Surgery for March 2019. This roundup includes the...

Awake Endoscopic Spinal Fusion Appears to Be Safe, Effective

Minimally invasive transforaminal lumbar interbody fusion without general anesthesia is safe

March 2019 Briefing – Orthopedics

Here are what the editors at HealthDay consider to be the most important developments in Orthopedics for March 2019. This roundup includes the latest...

March 2019 Briefing – Geriatrics

Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for March 2019. This roundup includes the latest...

Discharge, Interhospital Transfer Varies With Insurance Status

Uninsured patients more likely to be discharged, transferred versus privately insured patients

March 2019 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for March 2019. This roundup includes the latest...

March 2019 Briefing – Pain Management

Here are what the editors at HealthDay consider to be the most important developments in Pain Management for March 2019. This roundup includes the...

FDA Approves Mavenclad for Treating Multiple Sclerosis

Treatment indicated for patients with relapsing-remitting, active secondary progressive MS

March 2019 Briefing – Psychiatry

Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for March 2019. This roundup includes the latest...

March 2019 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for March 2019. This roundup includes the latest...

March 2019 Briefing – Allergy

Here are what the editors at HealthDay consider to be the most important developments in Allergy for March 2019. This roundup includes the latest...

March 2019 Briefing – Pulmonology

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for March 2019. This roundup includes the latest...

Nasopharyngeal Microbiota Could Help Diagnose Pediatric LRTIs

Research suggests nasopharyngeal microbiota can be valid proxy for lower respiratory tract microbiota

March 2019 Briefing – Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for March 2019. This roundup includes the latest...

March 2019 Briefing – Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for March 2019. This roundup includes the latest...

Increasing Dose for Total Body Irradiation Cuts Graft Failure

Findings seen in patients with severe hemoglobinopathies receiving haploidentical bone marrow transplantation

March 2019 Briefing – Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for March 2019. This roundup includes the latest...

March 2019 Briefing – Surgery

Here are what the editors at HealthDay consider to be the most important developments in Surgery for March 2019. This roundup includes the latest...

Cannabis Products Used Differ for Cancer, Noncancer Patients

Cancer patients more likely to use sublingual tincture form; noncancer patients often use vaporization form

March 2019 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for March 2019. This roundup includes...

March 2019 Briefing – Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for March 2019. This roundup includes the latest...

Undiagnosed Gestational Diabetes Ups Risk for Stillbirth

Women at risk for GDM who are screened, those diagnosed with GDM not at increased risk

March 2019 Briefing – Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for March 2019. This roundup includes the...

March 2019 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for March 2019. This roundup includes the...

Meta-Analysis Links Shift Work to Risk for Ischemic Heart Disease

Positive dose-response relationship ID'd between risk for IHD, increasing duration of shift work

March 2019 Briefing – Gastroenterology

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for March 2019. This roundup includes the latest...

March 2019 Briefing – Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for March 2019. This roundup includes the...

Changes to WIC Food Program Tied to Reversal in Obesity Trends

Trend of increasing obesity among 2- to 4-year-olds was reversed after 2009 changes

March 2019 Briefing – HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for March 2019. This roundup includes...

March 2019 Briefing – Emergency Medicine

Here are what the editors at HealthDay consider to be the most important developments in Emergency Medicine for March 2019. This roundup includes the...

Rates of CPR Before EMS Arrival Increased From 2000 to 2017

Compression-only, standard CPR have increased, linked to doubled survival rates versus no CPR

March 2019 Briefing – Infectious Disease

Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for March 2019. This roundup includes the...

March 2019 Briefing – Otolaryngology

Here are what the editors at HealthDay consider to be the most important developments in Otolaryngology for March 2019. This roundup includes the latest...

Vitamins, Carotenoids Associated With Lower Risk for Cataract

However, strongest evidence comes from cohort studies, not randomized controlled trials

March 2019 Briefing – Neurology

Here are what the editors at HealthDay consider to be the most important developments in Neurology for March 2019. This roundup includes the latest...

March 2019 Briefing – Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for March 2019. This roundup includes the latest...

AACR: High BMI Before 50 Raising Pancreatic Cancer Mortality

Twenty-eight percent of pancreatic cancer deaths due to higher BMI in those born in 1970 to 1974

Long-Term Phentermine Use Safe, Effective for Weight Loss

No difference in cardiovascular disease, death seen between those taking the drug for >12 versus ≤3 months

CDC: 2017 to 2018 Saw Increase in Enterovirus D68 Detection

EV-D68 detected in 13.9 percent of patients with acute respiratory illness in 2018

Therapeutic Ball Pits Found to Harbor Pathogenic Germs

Ball pits show wide variability in microbial colonization of infection-causing microorganisms

Patients With Worse RA Symptoms More Likely to Cut Alcohol Intake

No evidence found that alcohol use has beneficial effect in rheumatoid arthritis patients

High Prenatal Omega-6:Omega-3 Ratio Linked to ADHD at Age 7

Higher prenatal n-6:n-3 ratio in cord plasma linked to a higher ADHD score at age 7 years, but not at age 4

Perception of E-Cigarettes as More Harmful Than Cigarettes Increased

Increase observed in proportion who see e-cigarettes to be as harmful as, more harmful than cigarettes

Questions Remain About Safety of Parkinson Disease Psychosis Drug

Federal government has received high number of reports about deaths among patients taking Nuplazid

Simple Rapid Urine Test Can Help Diagnose Preeclampsia

Test outperforms other proposed diagnostic markers, with 86.7 percent accuracy

Recommendations Presented on Genetic Testing in Psychiatry

Guidelines emphasize that common genetic variants are not sufficient to cause psychiatric disorders

High Rates of Visual Problems Seen in Stroke Survivors

Three-quarters have visual problems, including impaired central vision, eye movement abnormalities

Shorter Reproductive Span May Up Risk for Dementia in Women

Dementia risk increased for menarche age ≥16 versus 13.0 years, natural menopause at <47.4 years

Three Interventions Involved in Decrease in Combat Mortality

Increased use of tourniquets, blood transfusions, rapid prehospital transport time key to mortality reduction

Starting Colorectal Cancer Screening at Age 45 Years Is Cost-Effective

But increasing participation for unscreened older adults would yield greater benefits at lower costs

Use of Biologics to Treat IBD in U.S. Adults May Be Suboptimal

While study design, methodology make comparisons difficult, adherence, continuation appear to be poor

Dietary Fatty Acid Intake Linked to Pediatric Asthma Morbidity

Omega fatty acid intake also modifies effect of indoor PM exposure on respiratory symptoms

Receiving Activated Charcoal Bag Tied to Proper Opioid Disposal

Less medication flushing, inappropriate garbage disposal seen for those receiving activated charcoal bag

Guidance Lists New First-Line Treatment for Severe Malaria in the U.S.

With discontinuation of quinidine, IV artesunate is now first-line drug for treatment of malaria

FDA Grants Approval for Hypogonadism Treatment

Jatenzo indicated for men with low testosterone due to certain conditions

Docetaxel Chemo Ups Survival in High-Risk Localized Prostate Cancer

Findings based on addition of docetaxel chemotherapy to androgen suppression, radiotherapy

Endocrine Society, March 23-26

The Endocrine Society 101st Annual Meeting and Expo The annual meeting of the Endocrine Society (ENDO 2019) was held from March 23 to 26 in...

Lifetime HTN Risk High for Black Men and Women, White Men

Lifetime risks are higher under AHA/ACC 2017 HTN threshold than JNC7 threshold for hypertension

California Man Awarded $80 Million in Roundup Lawsuit

Jury previously found Roundup was a significant factor in plaintiff's non-Hodgkin lymphoma

Cimzia Injection Approved for New Inflammatory Arthritis Indication

FDA grants approval for first treatment for nonradiographic axial spondyloarthritis

Doctors With Malpractice Claims More Likely to Leave Medicine

Physicians with five or more malpractice claims more than twice as likely to go into solo practice

Virtual Reality Cuts Time to Guide Catheter to Target Blood Vessels

Compared with fluoroscopic guidance, VR reduces time to select GDA, splenic, right hepatic artery

Drug Survival Rates Highest for Ustekinumab for Pediatric Psoriasis

Drug survival rates higher than for adalimumab, etanercept for all treatment and psoriasis types

Frailty May Up Fracture Risk in Patients With Type 2 Diabetes

Diabetes patients have higher frailty scores, which are tied to risk for incident fragility fractures

Tooth Loss May Up Pancreatic Cancer Risk in Black Women

Pancreatic cancer risk increased with tooth loss, especially loss of five or more teeth

Contact Lens-Based Antihistamine Delivery Effective

Eyes wearing lenses with etafilcon A, ketotifen have lower mean itching scores than controls

Nonsurgical Brain Stimulation Beneficial in Major Depressive Episodes

Ten of 18 reviewed treatment strategies linked to higher response versus sham therapy

Electronic Books Tied to Less Verbalization Among Parents, Toddlers

Pediatricians may want to promote shared reading of print books over electronic books

Higher Disease Burden for OA Than RA After Six Months

Similar disease burden seen at presentation for osteoarthritis, rheumatoid arthritis

Infants Born Weighing <400 g Who Survive at Risk for Severe Morbidity

One in five infants born at <400 g survives, but neurodevelopmental impairment common

FDA Approves Mayzent for Relapsing Multiple Sclerosis

Oral medication must be dispensed with important information about the drug's uses and risks

User Data From Medicine-Related Apps Routinely Shared

User data from 24 apps received or processed by 55 unique entities, including developers, service providers

Miscarriage Risk Strongly Tied to Age, Pregnancy History

Miscarriage has strong recurrence risk that increases with the number of miscarriages

Tx Adherence for Inflammatory Bowel Dz Lower in the Educated

Findings based on Indian study that also showed lower adherence overall for topical treatment

Hearing Loss Before Age 50 Tied to Higher Substance Use

Associations particularly pronounced for Rx opioid use disorders in those aged 18 to 34 with hearing loss

FDA: Breast Density Must Be Reported to Women During Mammograms

Proposed rule would also tighten FDA regulation of mammogram facilities

Adding Transition Services Does Not Aid Heart Failure Outcomes

No differences observed in readmission, ED visits, death at three months compared with usual care

Maltreatment in Childhood May Affect Course of Adult Depression

Links found among childhood maltreatment, relapse of depression as an adult, and altered brain structure

Taxane + Platinum Feasible for Adjuvant Tx in Endometrial Cancer

Tolerability, survival similar to that for doxorubicin + cisplatin for postoperative adjuvant chemotherapy

Many Eligible Patients Report Not Being Offered Statins

Fear of side effects, perceived side effects most common reasons for declining, discontinuing statins

ENDO: Sex Hormone Levels Tied to Telomere Length in Older Men

Estradiol independently linked to leucocyte telomere length in older men; SHBG inversely associated

Fewer Complications Seen With Uterine Fibroid Embolization

Both UFE and myomectomy are useful for treating symptomatic uterine fibroids

Smoking Seems Not to Be Linked to Increased Dementia Risk

No increased risk for dementia observed when adjusting for risk of death without dementia

ED Visits in Colorado More Frequent for Inhaled Versus Edible Cannabis

Visits for edible cannabis more likely to be for acute psychiatric symptoms, intoxication

Risk for Miscarriage Increased With Night Work During Pregnancy

Two or more night shifts during previous week tied to miscarriage risk after pregnancy week 8

ENDO: Levothyroxine Does Not Up Fertility in Women With TPO Ab

Live-birth rate did not increase for euthyroid women with thyroid peroxidase antibodies before conception

ENDO: Guidance Provided for Managing Diabetes in Seniors

Simplified med regimens, tailored glycemic targets recommended for those with cognitive impairment

ENDO: Recommendations Issued for Treating Osteoporosis

Pharmacological management recommended for postmenopausal women at high risk for fracture

Douglas County, Colorado, Ranked as Healthiest Community

Seven of top 20 communities were in Colorado; nearly all adults in these counties exercise

FDA Panel: Too Early to Ban Breast Implant Linked With Cancer

Evidence growing that certain breast implants can trigger a rare form of lymphoma

$775 Million Settlement Reached in Xarelto Lawsuits

Patients claim companies failed to warn about the risk for potentially fatal bleeding episodes

U.S. Measles Cases Hit 314 This Year

Meanwhile, Rockland County, New York, declares state of emergency over measles outbreak

Patient CKD App Ratings Do Not Correlate With Those of Nephrologists

No correlation seen for consumer ratings on the app stores with patient ratings of app quality

Statins Cut Risk for Major Vascular Events in Older Patients

Effects seen even among patients older than 75 years, though with less direct evidence of benefit

Blindfolding Leader Improves Pediatric Resuscitation Training

After five simulations, improvement in leadership skills was twice as high in blindfold group as in control group

Mild Congenital Heart Defects Tied to CVD Events

Lower-complexity ACHD associated with increased CVD risk regardless of conventional risk factors

Radiomic Features May Predict Response to Chemo in NSCLC

Peritumoral, intratumoral radiomic features on baseline CT scans may predict chemo response

New Approach Performs Well for Measuring CKD Quality of Life

Novel composite score is also reliable single-score summary of Kidney Disease Quality of Life-36

Guidance Offered for Managing Therapies in Children With Disability

Determining appropriate therapy dose is mainly subjective; provider should identify goals of therapy

Ocular Protein Levels May Be Useful for Alzheimer Testing

Low levels of protein biomarkers amyloid-β and tau protein in vitreous humor tied to low cognitive scores

Image-Guided Intervention May Ease Pain of Severe Tennis Elbow

Transcatheter arterial embolization may reduce pain, inflammation in persistent lateral epicondylitis

Policies Recommended to Reduce Sugary Drink Intake in Youth

Strategies aim to lower sugary beverage consumption among children and adolescents

ENDO: Older T1DM Patients Often Unaware of Hypoglycemic Status

Impaired awareness of hypoglycemia tied to greater amounts of time spent with glucose <70, <54 mg/dL

Patient CKD App Ratings Do Correlate With Those of Nephrologists

No correlation seen for consumer ratings on the app stores with patient ratings of app quality

Digital Intervention Ups Socialization in Children With Autism

Social outcomes improved with Superpower Glass wearable behavioral intervention

ENDO: Diabetes Underestimated With HbA1c Criteria

A1c misclassified 73.07 percent of diabetes mellitus cases defined by oral glucose tolerance test

Avocados Recalled by California Company

Recall issued by the company after samples tested positive for listeria

Mumps Outbreak at Temple University Reaches 74 Cases

University and local health department working together to combat outbreak

Aspiration Noninferior to Stent Retriever for Clot Removal

Direct aspiration is equally effective for large-vessel occlusion stroke, with lower device costs

HBV, HCV Control Aids Kidney Transplant Outcomes

Patients with viral suppression have outcomes similar to those of noninfected patients

Topical Immunotx for Actinic Keratosis May Prevent Cancer

Fewer patients treated with calcipotriol plus 5-FU developed SCC on treated face, scalp within three years

Brachytherapy Boost Ups Survival in Locally Advanced Cervical Cancer

Findings observed regardless of treatment duration; disparities for brachytherapy use seen in vulnerable populations

2019 Residency Match Day Was Largest in History

Internal medicine programs offered a record 8,116 categorical, 396 primary care positions

Low, High Levels of Physical Activity Tied to Reduced Mortality

All-cause mortality risk lower with 10 to 59 minutes of physical activity per week versus inactivity

Many Patients Still Employ Strategies to Reduce Prescription Drug Costs

33.6 percent of patients reported not taking medication as prescribed to reduce costs

ACC: New Guidelines Issued for Primary Prevention of CVD

Guidelines emphasize promotion of healthy lifestyle, including healthy diet, exercise, weight loss

Prenatal Pesticide Exposure Linked to Increased Risk for Autism

Increased risk seen for autism spectrum disorder and disorder with comorbid intellectual disability

Niraparib Extends Time Without Symptoms in Ovarian Cancer

Findings based on phase 3 study of maintenance therapy with PARP inhibitor following treatment

ACC: Ultrasound Surgery May Help Control Blood Pressure

At six months, patients who underwent renal denervation used less medication to control BP

American College of Cardiology, March 16-18

The American College of Cardiology's 68th Annual Scientific Session and Expo The annual meeting of the American College of Cardiology was held from March 16...

Analysis IDs Messages Behind Antivaccination Comments

Four distinct subgroups of comments were identified: trust, alternatives, safety, and conspiracy

Stricter Gun Laws Tied to Safer High Schools

Stricter gun laws tied to fewer student reports of being threatened/injured with a weapon at school

Tyson Recalls 69,000 Pounds of Chicken Strip Products

Recall due to consumer complaints about pieces of metal in the products

FDA: Higher Risk for Death Found With Venclexta in Multiple Myeloma

Enrollment suspended for trials investigating Venclexta for treatment of multiple myeloma

More Vascular Risk Factors Tied to Worse Brain Health

Most consistent associations across brain measures seen with smoking pack years, hypertension, DM

Younger Age at Menopause Tied to Higher Risk for Bladder Cancer

Women with menopause onset by age 45 at higher risk than those with onset at age 50 or older

State Breast Density Notification Laws May Up Ultrasound Use

But laws should require notification of possible benefits of supplemental screening

Critical Care Nurses’ Work Environments Improving

But most report lack of appropriate staffing; 33 percent intend to leave job within 12 months

Statins Tied to Insulin Resistance, Higher Serum Fasting Insulin

Ever use of statins associated with 38 percent increased risk for incident type 2 diabetes

Antibiotics, PPIs Tied to Higher C. Diff Risk in Hospitalized Children

Previous antibiotic exposure significant risk factor in combined studies but not in adjusted studies

Digital Breast Tomosynthesis Can Reduce Benign Biopsy Rate

Fewer benign biopsies necessary with DBT compared with full-field digital mammography

ACC: Robust Evidence Lacking for Many Cardiovascular Guidelines

Few recommendations in cardiovascular society guidelines supported by evidence from multiple RCTs

Older Age at Puberty Linked to Lower Odds of Multiple Sclerosis

After adjustment for effects on adult BMI, correlation between age at puberty with MS was attenuated

In Youth With ADHD, New-Onset Psychosis Up With Amphetamines

New-onset psychosis occurred in about one in 660 teens, young adults with ADHD receiving stimulants

Mothers of Children With Eczema More Likely to Have Exhaustion

For all measures, worse child atopic dermatitis severity linked to worse maternal sleep outcomes

Certain Dietary Patterns Linked to Cognitive Performance

Greater adherence to MedDiet, APDQS patterns in adulthood tied to better cognitive performance

Recent Increase Reported in Drug Overdose Deaths Involving Fentanyl

Numbers and rates increased for all sex, age, racial and ethnic subgroups, most public health regions

DG/health NATURALS Cough Syrup + Mucus for Infants Recalled

Product possibly contaminated with Bacillus cereus/Bacillus circulans

Cannabidiol Products Now Available at Hundreds of CVS Stores

Stores will carry the CBD products from marijuana company Curaleaf Holdings

FDA Approves New Device for Chronic, Moderate-to-Severe Heart Failure

Optimizer Smart system indicated for patients who are symptomatic despite optimal medical therapy

Younger Female Blood Donors Vulnerable to Iron Deficiency

In teens and women younger than 50, absent iron stores and anemia more common in blood donors

Three Factors Predict Psych Events With Drugs for Smoking Cessation

Anxiety, history of suicidal ideation/behavior, being white associated with higher risk for events

Prevalence of Severe Maternal Morbidity Increased Across Groups

Racial and ethnic disparities in severe maternal morbidity have remained persistent over time

Healthy Food Rx Could Be Cost-Effective for Medicare, Medicaid

Coverage for healthy food could improve health, reduce costs, and pay for itself after five years

Breast Density Categorization Varies With Screening Modality

Women screened with digital breast tomosynthesis have lower likelihood of high-density categorization

Overall, Physicians Are Happy and Enjoy Their Lives

Relationships found to be key to happiness; having friends at work impacts physician happiness

Sugary Drinks Tied to Cardiovascular Disease Mortality

Comparing extreme categories of consumption, SSB linked to increased CVD mortality, cancer mortality

Recommendations Issued for HSCT in Multiple Myeloma

Autologous stem cell transplant remains essential component of MM therapy in eligible patients

ACC: Catheter Ablation Does Not Cut Mortality, Stroke in A-Fib

But it is associated with more favorable quality-of-life end points at 12 months versus medical therapy

Daily Cannabis Use May Up Risk for Developing Psychotic Disorder

Daily cannabis use, especially high-potency types, linked to increased odds of psychotic disorder

FDA: First Treatment Approved Specifically for Postpartum Depression

Zulresso administered by IV infusion over 60-hour period; patients must be monitored during infusion

Trastuzumab Tied to Higher Long-Term Risk for Heart Failure

Increased risk for heart failure seen in breast cancer survivors given trastuzumab rather than chemo alone

Antiepileptic Drugs Not Tied to Dementia Risk

No increased overall risk found, but levetiracetam generic brands tied to higher dementia risk

Pregnancy-Adapted Algorithm Avoids Diagnostic Imaging for PE

Suspected pulmonary embolism safely ruled out in some pregnant women with diagnostic algorithm

FDA Takes New Look at Breast Implant Safety

Agency has acknowledged that breast implants may contain materials that affect people's health

Jury Finds Roundup a Major Contributor to Man’s Cancer

Landmark verdict could impact hundreds of other similar lawsuits

Practices for Reducing COPD Hospital Readmissions Explored

Communication emphasized as well as consideration of readmission as proxy for other health factors

Patients With Diabetes at Increased Risk for Sleep Apnea

In addition to known predictors of apnea, diabetes-related foot disease, insulin treatment up risk

Adenocarcinoma, High-Grade Dysplasia Up With Barrett Esophagus

But Barrett esophagus length has decreased, as has prevalence of low-grade dysplasia on endoscopy

Fewer Complications After MIRS Introduced for Endometrial Cancer

Introduction of minimally invasive robotic surgery linked to reduced odds of severe complications

Machine-Learning Models Allow Early Detection of Sepsis in NICU

Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent

Cancer Risk Modestly Elevated With Chronic Kidney Disease

Lower eGFR linked to elevated cancer risk relative to eGFR of 90 to 104 mL/min

Average of 8.8 Inactive Ingredients Found in Oral Medications

Overall, 92.8 percent of oral solid medications contain at least one potential allergen

Reported Cases of Spotted Fever Rickettsioses Rarely Confirmed

Elevated IgG antibody titer was most common supportive lab evidence for probable cases

Outcomes for AMI Improved During 1995 to 2014

Declines seen in AMI hospitalization, 30-day mortality, 30-day all-cause readmissions, one-year recurrent AMI

ACC: Dietary Cholesterol Ups Cardiovascular Disease Risk

Findings show dose-response increase in risk for cardiovascular disease, all-cause mortality

2011 to 2015 Saw Increase in Psychiatric ED Visits for Youth

Largest increases in emergency department visits seen for teens, African-Americans, Hispanic patients

ACC: Antibacterial Envelope Can Reduce CIED Infections

Incidence of major cardiac implantable electronic device infections significantly lower with envelope

Physician Burnout Rate Increased From 2014 to 2017

Early-career physicians most susceptible to burnout; late-career physicians less vulnerable

Young Child Goes to ED for Medicine Poisoning Every 10 Minutes

Safe medicine storage in the home needs to begin well before infants are on the move

EPA Proposal Will Allow Antibiotic Spraying of Citrus Crops

Consumer Reports warns of '26-fold increase in the use of streptomycin in plant agriculture'

MitraClip Device Approved for Patients With Secondary Mitral Regurgitation

Data show 47 percent reduction in risk for rehospitalization for HF symptoms with device implantation

Influences on New NIH Policy for Age Limits in Research Explored

'Inclusion Across the Lifespan' policy eliminates non-risk-justified age limits on research participants

Induction for Late-Term Pregnancies at 41 Weeks Tied to Small Benefits

Study could not show noninferiority of expectant management; outcomes good with both strategies

Opioid Prescriptions Dropped for New Users From 2012 to 2017

Decline seen in number of providers initiating opioid therapy in any patients who have not used opioids

Mental Health Issues Have Risen in Teens, Young Adults

Rates of depressive episodes, serious psychological distress, suicide-related outcomes have increased

AAOS: Supplement Use Low in Patients With Osteoporosis, Hip Fracture

Non-Caucasian minorities less likely to receive proper supplementation

Risk Profiles ID’d for Patients With Transplant Glomerulopathy

Five groups of patients with distinct features and outcomes identified using machine learning approach

Less Invasive Method Safely IDs Epilepsy Surgical Candidates

Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases

Guidelines Developed for Polymyxin Antibiotic Use

Polymyxin B recommended for routine use in invasive infections; colistin preferred for lower UTI

Testosterone Therapy in Hypogonadism Can Prevent Progression to T2DM

Men with prediabetes, hypogonadism achieved normal glucose regulation with TTh

ASCO: Guidelines Released for Early Detection, Treatment of CRC

Stratified guidelines emphasize optimal detection methods and treatments of colorectal cancer

Extra Weight in Adolescence Tied to Later Risk for Renal Cancer

Among Swedish men, overweight or obesity during adolescence tied to higher risk for renal cell carcinoma

Infertility in Women Linked to Modestly Elevated Cancer Risk

Overall risk higher for developing cancer; increased risks seen for uterine, ovarian, lung, thyroid cancers