Direct-Acting Antivirals Not Tied to Liver Cancer Recurrence

Among patients with previous complete response to HCC tx, DAA not linked to overall or early recurrence

Assessment Tools Aid Risk Planning at Nursing Homes

Residents with heart failure have higher rates of hospitalization, death, health instability

Many Teens Not Up to Date on HPV Vaccination

Only 15.7 and 34.8 percent of teens completed HPV vaccination before turning 13 and 15

Improved Genetic Risk Score Aids Type 1 Diabetes Classification

Revised risk score also improves newborn screening versus HLA genotyping alone

Home-Based Program Achieves Hypertension Control

Program uses Bluetooth-enabled monitoring, patient coaching by nurse practitioners and pharmacists

Cognitive Scores After Kidney Transplant Tied to Frailty

Cognitive function first improved then declined 1 to 4 years after transplant in frail recipients

Plasma Marker Predicts Allograft Failure in Lung Transplant

Average donor-derived cell-free DNA in highest tertile linked to increased risk for allograft failure

Initiative Tied to Decreased Racial Inequity in Breastfeeding

Compliance with Ten Steps program linked to increased breastfeeding in African-Americans

Psychopathic Traits in Adulthood Up With Child Lead Exposure

Higher childhood blood lead levels linked to increase in general psychopathy

Time to Breast Cancer Surgery Delayed for Non-Hispanic Blacks

Racial differences in TTS did not explain racial differences in overall survival with breast-conserving sx

Three-Week Immobilization Feasible for Some Ankle Fractures

Three-week cast, simple orthosis noninferior to six-week cast for stable, isolated Weber B-type fibula fracture

BP >120/80 mm Hg Linked to Lower Gray Matter Volume

Lower regional gray matter volume tied to higher peripheral BP in young adults aged 19 to 40 years

Gun Injury Hospitalization Cost Over $911 Million 2010 to 2015

Average cost of hospitalization was $32,700 per patient; about 10 percent due to readmissions

Fried Chicken, Fish Linked to All-Cause, Cardiovascular Death

For postmenopausal women, mortality risk increased with one serving fried chicken/fish per week

Flu-Like Illness Tied to Increased Relative Mortality in ESRD

~1,000 deaths of kidney failure patients each year in U.S. may be attributable to seasonal influenza

CDC: Proportion of Increased-Risk Deceased Organ Donors on Rise

Increased-risk donors significantly more likely to have positive HBV, HCV screening results

Measles Outbreak Prompts Public Emergency in Washington State

23 measles cases confirmed and two more suspected cases under investigation

Smoking Tied to Peripheral Artery Disease in African-Americans

Current smokers had increased risk for measures of subclinical peripheral artery disease

Short Duration Between Dinner, Bed Has No Effect on HbA1c

Duration of two hours or shorter between dinner and bedtime did not influence HbA1c changes

Levodopa + Carbidopa Does Not Modify Disease in Early Parkinson

Findings in patients with early Parkinson disease evaluated over the course of 80 weeks

Body Size, Physical Activity Could Impact Odds of Reaching 90

In women, height, BMI at age 68 to 70, and change in BMI impact odds of reaching longevity

Herd Protection Seen With 4-Valent HPV Vaccination

2006 to 2017 saw increase in vaccination; drop seen in HPV detection in vaccinated, unvaccinated

Renal Transplant Improves Survival in ESRD Due to Lupus

Survival benefit noted especially for cardiovascular disease in end-stage renal disease due to lupus nephritis

Artificial Intelligence System Can Triage Chest Radiographs

Average reporting delay reduced from 11.2 to 2.7 days for critical image findings in simulation

Mavoglurant Improves Visual Attention in Fragile X Syndrome

Increases noted in total absolute looking time, number of fixations to eye region while viewing faces

Benzodiazepine, Opioid Co-Usage Up in the United States

Increases also noted in co-use of nonselective and selective benzodiazepine receptor modulators

Liver Transplants for Alcohol-Linked Disease Increased From 2002 to 2016

Much of the increase due to decrease in hepatitis C virus infection as indication for transplant

Meta-Analysis: Aspirin Linked to Lower Risk for CV Events in Primary Prevention

Based on data from 13 trials with 164,225 participants, increased risk for major bleeding also noted

Doctors Should Encourage Exercise in Patients With Diabetes, CV Disease

Recommendations suggest doctors prescribe individualized exercise training for these patients

Ambient Air Pollution Exposure Linked to Sleep Apnea

Odds of sleep apnea increase with increase in nitrogen dioxide exposure, PM2.5 exposure

Endometrial Scratching Does Not Increase Live Birth Rate in IVF

No significant difference seen in frequency of live births, rates of ongoing, clinical, multiple pregnancy

Objectively Assessed Exercise Protective Against Depression

Objectively assessed, but not self-reported, physical activity protects against major depressive disorder

Insulin Price More Than Doubled in the United States

Insulin spending rose from about $2,900 in 2012 to about $5,700 in 2016

Most Stroke Survivors ≥50 Years Report Complete Mental Health

Odds of being in complete mental health up more than fourfold for those with at least one confidant

Marketing of Opioids Linked to Increased OD Mortality

Mortality from opioid overdoses up with increase in marketing value/capita, payments to doctors

Addition of BMT Not Indicated in Some With Peds Hypodiploid ALL

Bone marrow transplant not beneficial if no minimal residual dz after remission induction tx

Exome Sequencing Beneficial for Pediatric Kidney Recipients

Whole-exome sequencing-related molecular genetic diagnosis can have implications for clinical care

Poor Glycemic Control in Type 1 Diabetes Tied to Fracture Risk

Fracture risk up with T2DM and current use of rosiglitazone, pioglitazone regardless of glycemic control

Review Gives Guidance to Support Teens With Gender Dysphoria

Primary care providers can oversee potential medical management, connect families with support

For-Profit Nursing Program Grads Perform Worse on Licensure Test

14-fold increase seen in the number of for-profit nursing program graduates from 2007 to 2016

Guidelines Developed for Managing Severe Atopic Dermatitis

Management is generally in a stepwise manner, including moisturizers and avoiding triggers

Many New Cancer Patients Unaware of Their Hepatitis Status

Large proportion of participants with newly diagnosed cancer learned of infection through study

CDC: Opioid Prescribing Higher in Rural Versus Urban Areas

Odds of receiving an opioid prescription dropped significantly after March 2016 in all county groups

Messages for Increasing Parental Confidence in HPV Vaccine ID’d

Providing information on cancer prevention, avoiding expressing urgency increase parent confidence

Heberden’s Nodes in Fingers Tied to Knee Osteoarthritis

Significant associations seen between presence of HNs and MRI measures of knee arthritis

Medical Cannabis Decisions Being Made by Users, Not Doctors

Substantial portion of medical cannabis users stop taking or self-adjust dosage of pharmaceuticals

CDC: Slight Hike in Prevalence of Gastroschisis Since 2006-2010

Prevalence higher in areas with high and medium versus low opioid prescription rates

Canadian Syncope Risk Score IDs ED Monitoring Time Postsyncope

Half of arrhythmias identified within 2 hours in low-risk patients, within 6 hours in medium-, high-risk patients

FDA Chief Threatens to Halt E-Cigarette Sales

Commissioner Gottlieb 'horrified' at the recent rise in teen use of e-cigarettes

Repeat Tubal Procedures Up After Hysteroscopic Sterilization

Risk for additional tubal resection or ligation higher for hysteroscopic versus laparoscopic sterilization

Wearable Sensor Data Help ID Children With Internalizing Dx

Sensor data collected during fear induction task are analyzed using machine learning

Mandated Neonatal Abstinence Reporting Helps Quantify Cases

Five of six states with mandatory reporting receive case reports within 30 days of diagnosis

Melanoma Survival Varies Among U.S. States

Worse survival in states with more physicians; higher death rates in states with lower incidence

Oral Hepatoselective Glucokinase Activator Promising in T2DM

Clinically significant and sustained reduction in glycated hemoglobin was observed with TTP399

Inappropriate Antibiotic Rx Common in Privately Insured

Only 12.8 and 35.5 percent of fills were appropriate, potentially appropriate in outpatients

Variation in Revascularization for Asymptomatic SIHD Unexplained

Consistent benefit observed for patients with stable ischemic heart disease managed by revascularization

Trained Alert Dogs Can Detect Impending T1DM-Related Events

In study, individual dogs' performance varied for detecting hypoglycemic episodes, hyperglycemia

Frailty Could Increase Susceptibility for Dementia

Authors say frailty should be considered in clinical care, management of Alzheimer dementia

FDA Investigating Paclitaxel-Coated Balloons, Paclitaxel-Eluting Stents

Investigation triggered by meta-analysis showing possible increased mortality in PAD patients at 2 years

FDA Panel Has Tie Vote on New Type 1 Diabetes Drug

Zynquista is a once-daily pill meant to help type 1 diabetes patients manage their blood glucose levels

Assessing Symptoms After 4 Weeks of Psychotherapy Helpful in Teens

Week 4 seems better than week 8 for assessing response, implementing treatment augmentation

Mindfulness, Stress Linked to Menopausal Symptoms

Link between mindfulness and symptoms more robust in women experiencing higher stress

Medication Treatment for Substance Abuse Up in Facilities

2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016

Mandibular Contour Surgery Training System Beneficial

Improvements in clinical surgery time, accuracy with use of intraoral MCS training system

Wait Times Have Improved in VA Health Care System

Wait times similar to private sector in 2014 but shorter overall and in some specialties in 2017

Radiographic Knee Osteoarthritis Tied to Increased Risk for Death

Risk higher for cardiovascular disease, diabetes, renal mortality; lower risk for cancer mortality

Breast Cancer Patients Do Not Overreact to Genetic Testing

No increased cancer worry for multigene panel testing versus BRCA1/2-only test after cancer diagnosis

Prevalence of Knee OA Lower With Menopausal Hormone Therapy

Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model

Temporary Impairment in HRQOL After Teen Sports Concussion

Worse cognitive HRQOL and clinically meaningful impairment in school and overall HRQOL observed

Ertugliflozin Seems Safe, Effective for Type 2 Diabetes Treatment

Improvements seen in HbA1c, fasting glucose, body weight, blood pressure over two years

High Symptom Burden in Elderly Linked to Adverse Outcomes

Higher symptom count seen with increasing age and for women versus men

Nerve Transfer Promising for Acute Flaccid Myelitis Patients

Two children with AFM who underwent surgery for nerve transfer show functional recovery at two years

Hemochromatosis Mutation Linked to Other Morbidity

Higher rates of at least one incident-linked condition seen in men, women with HFE p.C282Y homozygosity

Achieving Healthy Diet From Sustainable Food Feasible

Global adoption of healthy reference diet would reduce morbidity, environmental degradation

Risk for Uninsurance in AMI Patients Reduced With Medicaid Expansion

Similar in-hospital mortality seen for low-income patients with AMI in expansion versus nonexpansion states

Asthma Undiagnosed in One in Five Urban Adolescents

Odds of being undiagnosed higher for girls, Asian-Americans versus white non-Hispanics

Antibiotics Often Inappropriately Prescribed for Bronchiolitis in ED

In almost 70 percent of bronchiolitis cases, antibiotics prescribed with no concomitant infection

Sex Differences Seen in Pursuit of Interventional Cardiology Career

Factors negatively influencing women are largely related to the culture of the subspecialty

FDA Approves First Generic Version of Epilepsy Drug Sabril

Generic equivalents held to same vigorous manufacturing standards as brand-name drugs

FDA Down to 5 Weeks of Funding to Review New Drug Applications

Agency cannot accept new fees or applications until the shutdown is over

WHO: Vaccine Hesitancy a Major Global Health Threat

Percentage of U.S. children 19 to 35 months who have not been vaccinated has quadrupled since 2001

Personalized Tx May Extend Life in CKD With Small Renal Tumors

Routine partial nephrectomy yielded longest life expectancy in patients with normal renal function

Accidental IV Dislodgement Reported to Be Very Common

Top 3 causes were confused patient, removal of catheter by patient, tape or securement loose

Liver Transplant Survival May Improve With Race Matching

Race-matched donor organ tied to improved survival for African-Americans with HCC undergoing transplant

Review Shares Best Practices for Evaluating Penicillin Allergy

Verifying reported allergies necessary to improve outcomes, prevent antibiotic resistance

Intermittent Fasts Plus Energy Restriction Best for Weight Loss

IF with 70 percent energy intake has better outcomes versus continuous diet restriction in obese women

Replacing Sitting Time With Activity Lowers Mortality Risk

No risk reduction seen when replacing prolonged sedentary bouts with shorter sedentary bouts

Complications Higher Than Expected for Invasive Lung Tests

Complication rates for invasive lung diagnostic procedures higher than those seen in clinical trials

Components of Ideal Cardio Health Cut Diabetes Risk

Lower risk for diabetes seen for those with normal fasting glucose, not impaired fasting glucose

Suicide Risk Up More Than Fourfold for Cancer Patients

Standardized mortality ratio highest for cancers of lung, head and neck, testes, bladder, Hodgkin lymphoma

Low-Income Women Lack Menstrual Hygiene Supplies

One in five low-income women in St. Louis cannot afford products on a monthly basis

Adoption of Advanced Health IT Capabilities Inconsistent

Degree of EHR standardization strongest predictor of health information technology adoption

High Levels of Activity, Motor Ability Linked to Better Cognition

Findings seen in older adults; independent correlations remained for those with Alzheimer disease

Coronary Artery Calcium May Help Predict CVD in South Asians

CAC incidence similar in South Asian men versus white, black, Latino men; higher than Chinese

Dermatologists’ Rx for Antibiotics Dropped From 2008 to 2016

However, rising use of antibiotics after dermatologic surgical visits is concerning

Statin Therapy Reduces Risk for Diabetic Retinopathy in T2DM

Reduced risk, slowed progression of retinopathy for Taiwanese patients with type 2 diabetes, dyslipidemia

Persistent Opioid Use High in Head, Neck Cancer Patients

Opioid use before treatment, tobacco use are risk factors for ongoing opioid use

Prices Still Explain High U.S. Health Care Spending

Health care prices explain difference in spending between United States and other countries

Drug Repurposing May Provide More Psychiatric Tx Options

Three drug classes tied to lower rates of self-harm and psychiatric stays with serious mental illness

Sociodemographic Factors Predict Recovery After Traumatic Injury

Gender, education are better predictors of long-term recovery than injury severity

Artificial Intelligence Can Use Routine ECGs to ID Heart Disease

Those with positive AI screen four times more likely to develop future ventricular dysfunction

Adverse Birth Outcomes Up for Women With H1N1 Flu in ICU

Pregnant women admitted to ICU with flu more likely to deliver preterm infants, low birth-weight infants

Chronic Fatigue Patients May Not Receive Proper ED Care

41 percent of patients did not go to ED, felt they would not be taken seriously or nothing could be done

Use of Diabetes Monitoring Tests in Primary Care Suboptimal

Less than 60 percent of patients with diabetes given HbA1c, lipid profile tests in preceding 12 months

High Fiber Intake Tied to Lower Risk for Noncommunicable Disease

Reduction in risk for range of critical outcomes greatest for daily dietary fiber intake of 25 to 29 g

Minority Med Students Report More Barriers to Dermatology

Students with lower incomes, ethnic minorities cite lack of diversity, socioeconomic barriers

Less Deep Sleep in Elderly Tied to Alzheimer Disease Markers

Poor-quality sleep in later life could be a noninvasive marker for deteriorating brain health

Algorithm Evaluates Cervical Images to ID Precancer, Cancer

Deep learning-based algorithm was validated using archived, digitized cervical screening images

CDC: E. Coli Outbreak Linked to Romaine Lettuce Is Over

25 people were hospitalized, including two who developed kidney failure; no deaths reported

U.S. Food Supply May Be at Risk Due to Government Shutdown

Number of routine food inspections performed by the FDA dropped sharply

FDA: Chocolates, Candies May Be Contaminated With Hepatitis A

Worker at Bauer's Candies facility in Kentucky tested positive for hepatitis A

Doctors Question State Lawsuits Over Pelvic Mesh Products

Lawsuits claim Johnson & Johnson did not fully disclose safety risks of transvaginal mesh products

E-Cigarette Aerosol Exposure Tied to Asthma Symptoms

Findings seen among youth reporting asthma diagnosis, secondhand exposure to e-cigarette aerosols

Outcomes Poorer for Medicaid Beneficiaries With STEMI

Rates of revascularization lower, in-hospital mortality higher for Medicaid versus privately insured

Seniors Still Report Barriers to Hearing Care Services

Difficulties accessing hearing care services seen particularly in older Americans with lower incomes

Private Equity Acquisition of Physician Practices Discussed

Critics warn private equity firms might focus on increased profitability at expense of patient care

Flu Vaccination Safe for Hospitalized Patients

With vaccination, risks reduced for readmission, outpatient visits, fever, clinical evaluations for infection

Transdermal HRT Not Linked to Increased Risk for VTE

But oral estrogen-only and combined hormone replacement tx tied to venous thromboembolism risk

Total Fertility Rates Vary by State

Total fertility rate for U.S. 16 percent less than number needed to replace population

Many Medical Cannabis Users Drive While Under the Influence

More than half of adults using medical cannabis for chronic pain reported DUIC within two hours of use

Nine Cases of Wound Botulism ID’d in Injection Drug Users

All patients used injection drugs; seven reported using black tar heroin and six practiced skin popping

No Increased Fall Risk With HTN Treatment in Older Women

Lower incidence rate ratios found for women with treated controlled hypertension, treated uncontrolled HTN

Long Work Hours Tied to Poor Glycemic Control in T2DM

Findings seen in young male, but not female, Japanese workers with type 2 diabetes mellitus

Fewer Than 5 Percent of Thyroid Surgery Patients Readmitted

Majority of readmissions occur within seven days of discharge and one-fourth within two days

Obesity Linked to Lower Gray Matter Brain Volume

Combination of overall obesity and central obesity linked to lowest gray matter volume

Fewer Complications Found With Hybrid Surgery for Esophageal Cancer

Incidence of intraoperative, postoperative complications lower in resectable esophageal cancer

Smartphone App Can Detect Early Signs of Opioid Overdose

App has high sensitivity, specificity for opioid-induced central apnea, respiratory depression

Measles Outbreak in New York State Largest in Recent History

There has been an increase in measles cases across the United States and worldwide

IC Nicardipine Promising for Tx of Spontaneous Coronary Slow-Flow

Administration of intracoronary nicardipine results in markedly accelerated coronary filling

Depression Tied to Worse Asthma Outcomes in Urban Teens

More than a fourth with asthma reported depressive symptoms, greater symptom severity

Increase in Brand-Name Drug Cost Mainly Due to Existing Drugs

Rising costs of oral, injectable generic and specialty drugs mostly driven by new product entry

Chemo-Radiation Combo Tied to Higher Survival in Peds Hodgkin

Five-year overall survival higher in patients who receive combined tx than those treated with chemo alone

Many Female Health Care Workers Live in Poverty

Half of black and Latina female health care workers earn less than $15/hour

Psychotherapy May Reduce Frequency of Nonepileptic Seizures

Adherence to psychotherapy linked to lower seizure frequency, higher quality of life, fewer ED visits

Nursing Intervention Promotes Better Sleep for Inpatients

Nighttime room entries reduced in unit where nurses received coaching, integrated SIESTA

Feeling Life Is Worthwhile Linked to Healthier Aging

Feeling tied to stronger relationships, greater social engagement and prosperity, less loneliness

Cervical Cancer Screening Rates ‘Unacceptably Low’

Just 64.6 percent of 30- to 65-year-old women up to date, but Pap-HPV cotesting has increased

Antibiotics Prescribed for Children More Often at Nonpediatric EDs

Frequency of guideline-concordant prescribing for respiratory conditions lower at nonpediatric EDs

Racial Differences ID’d in Some Biomarkers of Alzheimer’s Disease

African-Americans have lower mean CSF concentration of total tau, phosphorylated tau181

Toxicity From All-Grade AEs in Prostate CA Better Reflects QOL

Patient-reported toxicity scores more associated with quality-of-life outcomes than clinician-reported scores

Medical Marketing Has Increased in Past 20 Years

Considerable increase seen from 1997 through 2016, especially in direct-to-consumer advertising

USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit

Evidence convincing that universal prenatal screening reduces perinatal transmission of HBV

Costs Higher for Those With Comorbid Noncommunicable Diseases

Health expenditure greater for person with two diseases simultaneously than for the diseases separately

AI Technology IDs Genetic Diseases by Analyzing Facial Photos

DeepGestalt technology better than doctors at identifying a range of genetic syndromes

Women With CVD Have Worse Self-Reported Outcomes

Women with atherosclerosis also report lower aspirin, statin use and higher ED use versus men

Muscle Atrophy Occurs Rapidly in Critically Ill, Ventilated Children

47 percent of cohort experienced ≥11 percent decrease in diaphragm thickness after six days

Cancer Death Rate in U.S. Decreased Continuously From 1991 to 2016

Socioeconomic inequalities are widening, but racial gap in cancer mortality narrowing slowly

ACA Coverage Gains Could Erode Without Individual Mandate

However, individual market in California not expected to destabilize because of mandate penalty

Strict Ordinances Tied to Lower Youth Tobacco Use

Jurisdictions with most restrictive ordinances had lowest odds of ever cigarette use, past 30-day use

Single-Family Rooms May Benefit Very Preterm Infants

Reduced sepsis, increased breastfeeding rates observed; no difference in neurodevelopment vs. open bay units

Employment, Earning Losses Noted After Cardiovascular Events

Fewer patients admitted to hospital for MI, cardiac arrest, stroke working at three years postevent

Recent Nasal Preps Less Effective Than Injected Vax for Flu in Kids

Quadrivalent live attenuated flu vaccine less effective than inactivated vaccine for influenza A/H1N1pdm09

Meta-Analysis: Botulinum A Tops Placebo for Chronic Migraine

Frequency of chronic migraines significantly reduced after three months; QoL improved

Gabapentin Improves Sexual Function in Provoked Vulvodynia

Sexual function improved for gabapentin vs. placebo, but still lower than among matched pain-free controls

Income Volatility Linked to CVD, All-Cause Mortality

Increased risk seen with income volatility, more income drops during formative earning years

Flu Vaccine Cuts Flu-Related Hospitalization in COPD Patients

Flu-positive patients have higher crude mortality and critical illness versus flu-negative patients

Multimethod Approach Improves ID of Med Nonadherence

Use of provider report, medication possession ratio improved ID of nonadherence in youth with CKD

Rituximab Beneficial in Secondary Progressive MS

Treatment with rituximab linked to lower Expanded Disability Status Scale score, delayed progression

Screening Donated Blood for Zika Not Cost-Effective

Universal mini-pool nucleic acid testing only during high mosquito activity cost-effective in Puerto Rico

Rx Opioids Up Pneumonia Risk in Patients With, Without HIV

Risk greatest with higher-dose opioids and opioids with immunosuppressive properties

Exercise Can Consistently Lower Blood Pressure

Reductions in BP from exercise comparable but not as great as from medications

Childhood Hodgkin Lymphoma Survivors at Risk for Later Cancers

Survivors have 14-fold increased risk for developing a solid subsequent malignant neoplasm

Home Monitoring of Lung Function Feasible in Teens With Duchenne

Peak flow meter handheld device useful for adolescents with Duchenne muscular dystrophy

About 11 Percent of U.S. Adults Have Food Allergy

But nearly 20 percent think they are food-allergic; shellfish, milk, peanut are most common allergies

Risk for Suicide Increased in Year After Cancer Diagnosis

Higher suicide rates observed for cancers with poor prognosis, including pancreatic, lung cancer

Children Reaching Bone Maturity Earlier

In hand and wrist bones, epiphyseal fusion is initiated, completed earlier now than a century ago

Hypertension With Psoriasis Tied to More Cardiac Interventions

In patients with hypertension, psoriasis linked to increased risk for cardiovascular procedures, surgeries

Discharge One Hour After Naloxone for OD May Be Option

New rule has sensitivity, specificity of 84.1, 62.1 percent for patients receiving prehospital naloxone

Psychoeducational Intervention of Little Benefit in Breast Cancer

However, patients said that psychoeducational group study was important intervention for their life

Functional Milestones Identified for Persons With Down Syndrome

Most maintain personal hygiene by age 13, work independently by 20; 34 percent live independently

In-Hospital Morbidity, Mortality Up With Flu in Heart Failure

Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury

Sex Differences ID’d in Response to Glioblastoma Treatment

Standard therapy more effective for female versus male patients with glioblastoma

More Comorbidities, Lower Mortality for Holocaust Survivors

Mean age at death significantly higher for survivors versus controls

Risk for MCI Up With Progressive Cerebral Small Vessel Disease

Patients with hypertension with progressive cSVD have increased risk for mild cognitive impairment

Prenatal Valproate Exposure Linked to Increased ADHD Risk

Maternal use of other antiepileptic drugs not tied to increased ADHD risk

Health Benefits of Nonsugar Sweeteners Uncertain

However, large systematic review could not rule out harms from nonsugar sweeteners

Early Classification Predicts One-Year Trauma Outcomes

Six-week assessment of risk, protective factors explains one-year functional, health outcomes

School Nutrition Programs Slow BMI Gains in Children

Promoting healthier eating in middle school more effective than adding physical activity

Myelodysplastic Syndrome/AML Risk Increased After Chemo

Since 2000, risks for therapy-related myelodysplastic syndrome, AML up after chemo for solid cancers

Applying Population Health Data IDs Patients at Risk for CVD

Patients at risk for cardiovascular disease identified even with missing electronic health record data

Pediatric Mortality Rate From Opioid Poisoning Rose 1999 to 2016

Pediatric mortality rate increased from 0.22 to 0.81 per 100,000; rates highest for 15- to 19-year-olds

Artificial Intelligence Can Detect, Classify Acute Brain Bleeds

Further, the system can justify its decisions using an atlas of training CT images

Child Pneumonia Rate Dropped Globally From 2000 to 2015

Number of clinical pneumonia episodes in children <5 years reduced 22 percent in developing countries

Study Reveals High Rate of Phlebitis Caused by IV Cannulas

Rates of other complications similar to those in previously published reports

Patients With Sleep Apnea Have Increased Gout Risk

Among OSA patients, risk for developing gout is highest one to two years after the index date

Sexual-Minority Patients Prefer Nonverbal Data Collection

Collecting sexual orientation and gender identity info nonverbally in ED improved communication

Antidepressant Use in Seniors Linked to Risk for Hip Fracture

Odds ratio highest 16 to 30 days before Rx filled

Classification of Psoriasis Severity Depends on Definition

Authors call for international standardization defining moderate-to-severe psoriasis

Breast Cancer Disparities Mostly Explained by Facility Factors

Findings based on analysis of white, black, and Hispanic patients in Chicago

Clinical Tool Rapidly Assesses Post-Intensive Care Syndrome

27-item questionnaire found to be valid clinical tool for assessing PICS

International Radiation Doses Vary for CT Exams

Dose variation due to institutional decisions regarding technical parameters

Newborn Genomic Sequencing Can Identify Disease Risk

Sequencing detects risk for disorders not anticipated based on infants' known clinical, family history

Anemia Criteria Assist Decision on Type of Colorectal Cancer Screen

Risk for proximal cancers low among patients without broad-definition anemia and/or abdominal mass

Many Adults in 50s, Early 60s Worried About Health Insurance

More than one-quarter have little or no confidence they can afford health insurance over the next year

Moderate Drinking Not Harmful for Seniors With Heart Failure

Compared with abstinence from alcohol, increased survival seen with moderate drinking

College Students at Increased Risk for SgB Meningococcal Dz

Students, parents, health care providers should be aware of the availability of MenB vaccines

Proportion of Cancers Due to Excess Body Weight Varies by State

Population-attributable fraction varied from 3.9 percent in Montana to 6.0 percent in Texas for men

One in 10 EMS Encounters for Involuntary Psychiatric Holds

Alameda County study shows 41 percent directly transported to standalone psych emergency services

Price of Alirocumab Would Have to Be Cut to Be Cost-Effective

Price of alirocumab would have to decrease from original cost of $14,560 to $1,974 to be cost-effective

No Increased Fracture Risk With Canagliflozin in Type 2 Diabetes

Rate of the primary outcome was similar for canagliflozin, glucagon-like peptide-1 agonist