February 2019 Briefing – Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for February 2019. This roundup includes the...

February 2019 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for February 2019. This roundup includes the latest...

Electronic Order Set May Reduce Inappropriate ECG Monitoring

Findings observed among hospitalized patients not in an intensive care unit

CDC: Mortality Rates Continue to Decrease for Hispanic Adults

Difference in death rates between non-Hispanic white, Hispanic adults widened from 2000 to 2017

Injection Timing Tied to Risk for Infection in Rotator Cuff Repair

Corticosteroid injection in the month prior to surgery linked to increased risk for surgical site infection

Type 2 Diabetes May Impact Sleep in Middle-Aged Women

Findings show more sleep-related symptoms of symptoms of higher severity

Risk Profiles ID’d for Patients With Transplant Glomerulopathy

Five groups of patients with distinct features and outcomes identified using machine learning approach

Malnutrition Ups Risk of Postop Issues in Pediatric Crohn Disease

In propensity-matched analysis, mild, severe malnutrition linked to elevated odds of complications

CDC: Cancer Death Rates Decreased, Heart Disease Deaths Rose

Cancer death rates decreased from 1999 to 2017; heart disease deaths dropped to 2011 and then increased

Educational Handout May Increase Receipt of Child Flu Shot

Providing educational intervention in waiting room before pediatric provider visit may be beneficial

0.49 Percent of U.S. Population Reports Current Sesame Allergy

Overall, 81.6 percent of patients with convincing sesame allergy reported at least one additional food allergy

Fewer Complications After MIRS Introduced for Endometrial Cancer

Introduction of minimally invasive robotic surgery linked to reduced odds of severe complications

Secondhand Smoke Exposure Linked to Chronic Kidney Disease

Prevalence of chronic kidney disease, CKD development increased with exposure to secondhand smoke

Achievement of Targets in T2DM Varies by Season

Achievement rates for all three targets and for HbA1c, BP, LDL-C are lowest in the winter

Some Heart Failure Patients May Benefit From CRT Defibrillator

Findings seen in patients with non-left bundle branch block eligible for cardiac resynchronization therapy

Receipt of Breast Milk Increases With Gestational Age at Birth

71.3 percent of extremely preterm and 84.6 percent of term infants received any breast milk

January 2019 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for January 2019. This roundup...

More Than Half of Internal Medicine Graduates Choosing Primary Care

Programs with a majority of graduates entering primary care less likely to have X+Y scheduling

Losing 20 lb Improves Knee Replacement Outcomes

Findings based on group of morbidly obese patients with varying weight loss before surgery

Metformin May Cut Mortality Risk in Post-Pancreatitis Diabetes

Survival benefit not seen with ever use of metformin for pancreatic cancer-related diabetes

Sertraline Tops CBT for Reducing Depression in Dialysis Patients

Engagement intervention on treatment acceptance has no effect on acceptance of depression treatment

Review Links Adverse Events to Use of Herbal Meds in Pregnancy

Increased odds of preterm birth with almond oil; oral raspberry leaf linked to cesarean delivery

Preventive Drugs Often Used in Last Year of a Cancer Patient’s Life

Preventive drugs, including antihypertensives and statins, frequently continued until final month of life

Suboptimal BP, Fasting Glucose Tied to Atrioventricular Block

Two modifiable variables potentially explain more than half of all atrioventricular blocks

GDM Linked to Increased Cardiovascular Event Risk Postpartum

In analysis restricted to women who did not develop T2DM, GDM still linked to increased risk

2012 to 2018 Saw Substantial Rise in Naloxone Dispensing

Regional variation in naloxone dispensing considerable; rates lowest in most rural counties

Nonsuicidal Self-Injury Rate Up in Sexual-Minority Youth

Prevalence of NSSI ranged from 38.04 to 52.97 percent for sexual-minority youth between 2005 and 2017

Many Trust Doctors, Nurses Over Other Sources of Health Advice

Although most people agree that vaccines are safe, the proportion is lower in high-income regions

Intervention Can Reduce Orders for Inpatient Urine Cultures

Intervention includes notifications to providers, changes to order sets, new urine culture reflex tests

Risk for MCI Up With Progressive Cerebral Small Vessel Disease

Patients with hypertension with progressive cSVD have increased risk for mild cognitive impairment

Cardiovascular Risk Increased During Gender Transition

Transwomen had higher incidence of strokes, VTEs than reference men and women

April 2019 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for April 2019. This roundup includes the latest...

Screening for Opioid-Related Low Testosterone Underused

Rates of screening, treatment for low testosterone higher for prolonged versus short-term opioid users

May 2019 Briefing – Anesthesiology

Here are what the editors at HealthDay consider to be the most important developments in Anesthesiology for May 2019. This roundup includes the latest...

Opioid Prescriptions Dropped for New Users From 2012 to 2017

Decline seen in number of providers initiating opioid therapy in any patients who have not used opioids

Medicare Advantage Patients Have Higher Readmission Rates

Higher adjusted readmission rates seen for AMI, CHF, pneumonia with Medicare Advantage

Teva Recalls Two Blood Pressure Medications

Tablets tainted with N-nitrosodiethylamine, a suspected human carcinogen

March 2019 Briefing – Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for March 2019. This roundup includes the...

FDA: French Soft Ripened Cheese Possibly Contaminated

Agency warns of potential Listeria monocytogenes contamination of l'Explorateur cheese

Many Female Health Care Workers Live in Poverty

Half of black and Latina female health care workers earn less than $15/hour

February 2019 Briefing – Anesthesiology

Here are what the editors at HealthDay consider to be the most important developments in Anesthesiology for February 2019. This roundup includes the latest...

Trial Tests CRISPR Gene-Editing to Treat Sickle Cell Disease

Study seeks to recruit up to 45 adults with severe sickle cell disease

ENDO: Guidance Provided for Managing Diabetes in Seniors

Simplified med regimens, tailored glycemic targets recommended for those with cognitive impairment

2018 to 2019 Influenza Season in U.S. Was Longest in 10 Years

Season was of moderate severity and lasted 21 weeks; illness mainly attributed to influenza A viruses

Use of Pain Reliever Tramadol May Up Risk for Hypoglycemia

Retrospective analysis of adverse events reported to FDA shows risk similar to that seen with methadone

Pressure Injuries at Time of ICU Admission Tied to Longer Stays

Pressure injuries also may have modest association with higher risk for mortality

Rates of Anal Cancer Precursors High in Women Living With HIV

Authors call for new screening strategies for anal cancer prevention in women living with HIV

Ulcerative Colitis Outcomes Similar for Smokers, Nonsmokers

No significant difference in rates of flares, thiopurine use, hospitalization for persistent smokers, quitters

Statins Cut Risk for Major Vascular Events in Older Patients

Effects seen even among patients older than 75 years, though with less direct evidence of benefit

Ibrance Approval Expanded to Include Men With Breast Cancer

Kinase inhibitor approved in combination with endocrine therapy for male patients with breast cancer

FDA Warns of Infections From Fecal Transplants After One Death

Fecal microbiota transplantation is a still-experimental procedure, as yet unapproved by the FDA

For TAVR, Inverse Link Identified for Hospital Volume, Mortality

Higher 30-day mortality in lowest- versus highest-volume quartile of transfemoral TAVR procedures

Family History of Diabetes Tied to Higher BMD in Normoglycemia

Lumbar spine, femoral neck BMD higher in postmenopausal women with first-degree family history

Medicaid Expansion Increases Access to Kidney Transplants

Increases in Medicaid-covered preemptive kidney transplants greater in Medicaid expansion states

Racial, Ethnic Underrepresentation in Med School Matriculants

Black, Hispanic, American Indian or Alaska Native students underrepresented versus U.S. population

ASCO: Pembrolizumab Noninferior to Chemo in Advanced Gastric Cancer

For patients with PD-L1 combined positive score of ≥10, pembrolizumab prolongs overall survival

Women With CVD Have Worse Self-Reported Outcomes

Women with atherosclerosis also report lower aspirin, statin use and higher ED use versus men

No Increase in Complications Seen With Abdominoplasty in Obese

Rates of perioperative complications no higher in obese than nonobese patients

Marriage Associated With Lower Dementia Risk

Divorced, widowed, separated men show greater risk for dementia than women in same categories

FDA Approves Personalized Tx for Metastatic Bladder Cancer

Balversa indicated for treatment of bladder cancer with FGFR3 or FGFR2 genetic alteration

Rate of Dual Burden 37 Per 10,000 Births in California

Significant predictors of dual burden of preterm birth, severe maternal morbidity include smoking, HTN

1998 to 2015 Saw Increase in Outpatient Depression Treatment

Proportion using psychotherapy decreased; proportion receiving drugs remained stable

Global Burden of Musculoskeletal Diseases on the Rise

Significant increases seen worldwide, but burden highest in Europe

Aspirin May Improve Liver Function After Embolization of HCC

Study suggests aspirin is hepatoprotective, improves survival by reducing liver inflammation

2003 to 2014 Saw Incidence of Herpes Zoster Drop in Children

Vaccinated children had 78 percent lower rate of HZ incidence than unvaccinated children

High Physical Activity Levels Tied to Coronary Artery Calcification

But no increased mortality risk with high physical activity levels, CAC of ≥100 Agatston units

Risk for Arterial Hypertension Up With Air Pollutant Exposure

Residential exposure linked to AH, reduced HDL cholesterol for individuals living in multistory houses

Users of Flavored E-Cigarettes Report Greater Satisfaction

Flavor is common reason for vaping initiation, more likely to motivate adults aged 18 to 24 years to start

Dipeptidyl Peptidase-4 Inhibitors May Up Pancreatic Disease Risk

Risks for pancreatitis, pancreatic cancer higher in Korean patients with newly diagnosed T2DM

February 2019 Briefing – Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for February 2019. This roundup includes the...

Acetaminophen in Pregnancy May Affect Childhood Behavior

12 variables, mainly features of hyperactive or attentive behavior, tied to acetaminophen use

Recommendations Issued for HSCT in Multiple Myeloma

Autologous stem cell transplant remains essential component of MM therapy in eligible patients

Dietary Vitamin A Intake Tied to Reduced Risk for Squamous Cell Carcinoma

Cutaneous SCC risk reduced for highest versus lowest quintile of vitamin A, retinol, some carotenoids

Hearing Aid Use Tied to Lower Risk for Dementia, Depression, Falls

Findings revealed in large study of older adults with hearing loss

Quality-Improvement Tool Improves Iron Outcomes in Pregnancy

Toolkit includes diagnostic and management pathways plus educational resources

Comorbid Neck Injury Up for Women With Concussion

For all concussion-related ED visits, odds of comorbid neck injury up for females ages 5 to 49

Some Cancer Trends Differ for Oldest Old in the United States

Trends similar to 65- to 84-year age group, but risk elevated for some cancers, diagnosis at later stages

Romosozumab Increases Bone Formation, Cuts Bone Resorption

Lower values for resorption end points at month two persisted to month 12, indicating reduced turnover

Stricter Gun Laws Tied to Safer High Schools

Stricter gun laws tied to fewer student reports of being threatened/injured with a weapon at school

Ibrutinib-Rituximab Beats Chemoimmunotherapy for CLL

Progression-free, overall survival improved in the ibrutinib-rituximab group at three years

Many Surgeons Still Performing Inappropriate Vascular Access Sx

About 20 percent fail to meet arteriovenous fistula rate benchmark

‘Brain Vital Signs’ Detect Concussion-Related Changes

Six brainwave metrics can detect even subclinical changes in nonconcussed hockey players

Sleep Duration Tied to Adverse Measures of Glycemia

Findings seen among adults with prediabetes or recently diagnosed, untreated type 2 diabetes

Burden of Heart Failure-Related CVD Mortality Higher in Blacks

Burden significantly higher among young and middle-aged black versus white men and women

Up to Half of Patients Do Not Disclose Imminent Threats to Physicians

Patients withhold issues of depression, suicidality, abuse due to embarrassment, fear of being judged

Initiating Empirical Tx for Sepsis Reduces Blood Culture Sensitivity

12 percent difference seen in proportion of positive blood cultures before and after antimicrobial therapy

March 2019 Briefing – Radiology

Here are what the editors at HealthDay consider to be the most important developments in Radiology for March 2019. This roundup includes the latest...

ACS Sets Goal to Cut Cancer Mortality 40 Percent by 2035

Goal based on decrease in overall cancer death rates at pace seen among college graduates

Guidelines Developed for Reducing Suicide in Veterans

Authors examined benefits, harms of nonpharmacologic, pharmacologic approaches

Over 17.7 Million Cosmetic Procedures Performed in U.S. in 2018

Increasing trend seen in body-shaping procedures, including 4 percent increase in breast augmentation

Stroke Patients Infrequently Screened, Treated for Bone Loss

5.1 percent of patients with stroke, 2.9 percent of those without prior testing had bone mineral density test

Autologous Stem Cell Transplant May Aid Some With Nodal PTCL

Prospective cohort study suggests benefit of ASCT for some with nodal peripheral T-cell lymphoma

Ultrasound of Calcaneus Efficient for Screening Bone Health

Ultrasound readings of left or right foot can predict good versus poor bone quality

ADA 2019 Standards of Care Emphasize Patient-Centered Care

Updates include use of SGLT-2 inhibitors and GLP-1 receptor agonists for T2DM, CVD; endorsed by ACC

Children With Atopic Dermatitis Have Worse Sleep Quality

Similar total sleep duration seen for children with, without active atopic dermatitis

Next-Gen Sequencing of CSF Improves Diagnosis of CNS Infections

Eight of 13 diagnoses made solely by metagenomic NGS had likely clinical effect, seven guided treatment

Price of Alirocumab Would Have to Be Cut to Be Cost-Effective

Price of alirocumab would have to decrease from original cost of $14,560 to $1,974 to be cost-effective

Stimulation of Targets in Brain May Up Recollection in Seniors

Effects of stimulation were greater on fMRI recollection signals versus recognition signals

Depressive Symptoms Higher During Internal Medicine Internship

Faculty feedback, learning experience in inpatient rotations, work hours tied to change in symptoms

Malawi First Country to Immunize Children Against Malaria

The vaccine, called Mosquirix, was approved by the European Medicines Agency in 2015

May 2019 Briefing – Pulmonology

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for May 2019. This roundup includes the latest...

Vaping Likely to Blame for 14 Hospitalizations in Two States

Patients had severe respiratory symptoms; vaping the only apparent link between the cases

FDA Approves First Generic Nasal Spray Against Opioid Overdose

Product is also first generic naloxone nasal spray approved for use by people without medical training

Malnutrition Common in Older Brazilians Hospitalized for Cancer

Most prevalent nutrition impact symptoms include no appetite, dry mouth

Gentamicin Appropriate Second-Line Therapy to Ceftriaxone for Gonorrhea

Two weeks after treatment, infection cleared for 98, 91 percent treated with ceftriaxone versus gentamicin

Burden of Sudden Cardiac Death Higher in Black Men, Women

Known factors explain 65.3 percent of excess SCD risk in African-Americans, especially women

Infections Tied to Subsequent Risk for Acute Ischemic Stroke

Correlation highest for UTI; smaller-magnitude associations seen for UTI with intracerebral hemorrhage

Recent Plateauing Seen in Prevalence of Diagnosed Diabetes

Following increase from 1990 to 2007, incidence rates significantly decreased since 2007

Smartphone App Can Detect Early Signs of Opioid Overdose

App has high sensitivity, specificity for opioid-induced central apnea, respiratory depression

Wireless Sensor System Feasible for Monitoring Vital Signs in NICU

Operation possible when immersed in water and compatible with essential medical imaging

Three-Week Immobilization Feasible for Some Ankle Fractures

Three-week cast, simple orthosis noninferior to six-week cast for stable, isolated Weber B-type fibula fracture

Meta-Analysis Does Not Link Vitamin D Supplements, Drop in MACE

Vitamin D supplementation not linked to reduction in risk for major adverse cardiovascular events

Odds of Developing C. Diff Increased in Older Cancer Patients

Risk for Clostridiodes difficile infection significantly greater with diagnosis of liquid tumors

One in Seven Internal Medicine Residents Report Being Bullied

International graduates, lower-performing residents, non-native English speakers most likely to report bullying

April 2019 Briefing – Cosmetic Surgery

Here are what the editors at HealthDay consider to be the most important developments in Cosmetic Surgery for April 2019. This roundup includes the...

Quitting Smoking Linked to Lower CVD Risk Within Five Years

However, compared with never smokers, former smokers' risk remains elevated beyond five years

Early Intensive Treatment May Improve Long-Term MS Outcomes

Mean five-year change lower in Expanded Disability Status Scale score with early intensive treatment

Racial Disparities Persist in Revascularization for CHD

Rates of revascularization lower for black women with acute coronary syndrome, coronary heart disease

2011 FDA Safety Message Tied to Drop in Transvaginal Mesh Use

Proportion of apical procedures using transvaginal mesh decreased in year after safety communication

Darolutamide Slows Spread of Castration-Resistant Prostate Cancer

Significant survival benefit seen, adverse events similar between darolutamide and placebo

Infliximab Introduction Has Not Cut IBD-Related Hospitalizations

Introduction of infliximab did not lead to drop in hospitalization, intestinal resection, colectomy

February 2019 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for February 2019. This roundup...

T2DM Risk in Offspring Up With Maternal Overweight, Obesity

Offspring of women who are overweight or obese during pregnancy have higher risk for type 2 diabetes

Rotavirus Vaccination Tied to Lower Risk for T1DM in Children

No association seen for partial vaccination and incidence of type 1 diabetes

HPV Educational Video May Increase Vaccination Rates

Adolescents whose parents watched the video were three times more likely to be vaccinated

Structural, Clinical Barriers Prevent Cancer Trial Participation

Trial unavailable at patients' institution 55.6 percent of the time; 21.5 percent of patients ineligible

ASCO: Guidelines Released for Early Detection, Treatment of CRC

Stratified guidelines emphasize optimal detection methods and treatments of colorectal cancer

Most HPV-Linked Cancers Due to Types Targeted by 9vHPV Vaccine

In 2012 to 2016, 92 percent of cancers attributable to HPV due to HPV types targeted by 9vHPV vaccine

August 2019 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for August 2019. This roundup includes the latest...

Messages for Increasing Parental Confidence in HPV Vaccine ID’d

Providing information on cancer prevention, avoiding expressing urgency increase parent confidence

Naltrexone Implant Helps HIV Patients Prevent Opioid Relapse

Compared with oral naltrexone, implant also improved HIV outcomes among those with opioid dependence

Cardiorespiratory Fitness Tied to Lower Risk for Lung Cancer, CRC

For those diagnosed with lung cancer, CRC, higher CRF tied to lower risk for subsequent death

Improvement Needed in Doctor-Patient Lung Cancer Screening Discussions

Crude estimated rates of physician-patient discussion dropped from 6.7 to 4.3 percent in 2012 to 2017

Increasing DTP3 Coverage Tied to Drop in Diphtheria Cases in Under 15s

In countries with higher case counts, 66 percent of case-patients were unvaccinated, 63 percent <15

Improved Genetic Risk Score Aids Type 1 Diabetes Classification

Revised risk score also improves newborn screening versus HLA genotyping alone

Fewer Than 5 Percent of Thyroid Surgery Patients Readmitted

Majority of readmissions occur within seven days of discharge and one-fourth within two days

Individualized Care Plans Advised for T2DM With Heart Failure

Diabetes mellitus, heart failure often occur concurrently, with each increasing risk of the other

CDC: Salmonella Outbreaks Linked to Backyard Poultry

52 people sickened and five people have been hospitalized; no deaths reported

CDC: First Confirmed ID of ‘Kissing Bug’ in Delaware

Triatoma sanguisuga insect can transmit parasite that causes Chagas disease

Mental Health Treatment, Diagnoses Up in Military Children

Mental health diagnoses, visits, prescriptions increased since 2003

More Social Contact at Age 60 Linked to Lower Dementia Risk

More frequent social contact during midlife linked to better subsequent cognitive trajectory

Cancer Survivors Have High Prevalence of Chronic Pain

Prevalence higher for those with less than high school education, low income, public insurance

Machine-Learning Models Allow Early Detection of Sepsis in NICU

Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent

Prevalence of Malignancy High in Takotsubo Syndrome Patients

Those with malignancy have higher long-term mortality but no difference in short-term outcomes

Fifteen Million Patients Will Need First-Course Chemo in 2040

Number of cancer physicians required to deliver optimal chemo set to increase to 100,000 by 2040

Early Neuromuscular Blockade No Better in ARDS Patients on Vent

Mortality similar for those receiving continuous infusion of cisatracurium, lighter sedation targets

Some Characteristics Unique to Depression Before, After Birth

Background traits tied to chronic depression; delivery experience tied to early postpartum depression

Awareness, Use of PrEP on Rise Among Men Who Have Sex With Men

PrEP awareness increased by 50 percent overall from 2014 to 2017; however, use is still low

Early Classification Predicts One-Year Trauma Outcomes

Six-week assessment of risk, protective factors explains one-year functional, health outcomes

Taxane + Platinum Feasible for Adjuvant Tx in Endometrial Cancer

Tolerability, survival similar to that for doxorubicin + cisplatin for postoperative adjuvant chemotherapy

Endometrial Scratching Does Not Increase Live Birth Rate in IVF

No significant difference seen in frequency of live births, rates of ongoing, clinical, multiple pregnancy

Prescription Drug Misuse Common in High Schoolers

44 percent of high school seniors who misuse prescription drugs have multiple drug sources

Hospitalization for Upper GI Bleed Highest With Rivaroxaban

Upper gastrointestinal bleeding hospitalization risk lower for anticoagulant tx with PPI cotherapy

Stress Test-Based Physiological Age May Be Superior Mortality Predictor

Physiological age based on exercise stress testing performance better predictor than chronological age

Most U.K. Patients With UTI Receive Antibiotics on Same Day

Represcription rate at 28 days only 4.1 percent from 2011 to 2015; slight increase seen for men over time

Overlapping Surgery Appears Safe for Common Procedures

No significant difference seen in in-hospital mortality, complication rates, but surgery length increased

Key Cystic Fibrosis Pathogens Reduced With Ivacaftor Use

Ivacaftor use linked to reductions in P. aeruginosa rates, prevalence of S. aureus, Aspergillus species

July 2019 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for July 2019. This roundup includes the latest...

Overall, Physicians Are Happy and Enjoy Their Lives

Relationships found to be key to happiness; having friends at work impacts physician happiness

Outcomes of Importance ID’d for Peritoneal Dialysis Patients

PD-related infection, mortality, fatigue are highest-ranked outcomes for patients, caregivers

Nonphysican Practitioners Filling Post-ACA Primary Care Gap

New Medicaid beneficiaries seeing nurse practitioners, physician assistants

January 2019 Briefing – Radiology

Here are what the editors at HealthDay consider to be the most important developments in Radiology for January 2019. This roundup includes the latest...

Infections May Up Risk for Developing Sjögren Syndrome

Lung, skin, urogenital infections tied to increased risk for developing primary Sjögren syndrome

Two Algorithms Can ID Patients at Risk for HIV, PrEP Candidates

Algorithms use data from EHRs to identify candidates for preexposure prophylaxis

Components of Ideal Cardio Health Cut Diabetes Risk

Lower risk for diabetes seen for those with normal fasting glucose, not impaired fasting glucose

Costs Higher for Those With Comorbid Noncommunicable Diseases

Health expenditure greater for person with two diseases simultaneously than for the diseases separately

FDA: High Levels of Heavy Metals Found in Kratom Products

Products contain levels of lead and nickel at concentrations that exceed safe daily intake

Excess Caffeine May Be a Trigger for Episodic Migraine Headaches

Three or more servings of caffeinated beverages associated with higher odds for headache that day

FDA Receives an ‘F’ in Tobacco Prevention Report Card

American Lung Association releases State of Tobacco Control 2019 report

Bill Would Raise U.S. Legal Age to Buy Tobacco to 21

Fourteen states have already enacted laws raising the minimum age for tobacco sales to 21

LENI Flap Reliable for Nasal Defect Reconstruction

Lateral extended nasal island myocutaneous flap can bridge distances up to 1.8 cm

Direct-Acting Antivirals Cut Mortality in Chronic Hepatitis C

Mortality, hepatocellular carcinoma risk reduced after adjustment for potential confounders

Firearms Leading Cause of Death Among Young Adult Men

Findings in U.S., Mexico, Brazil, Colombia based on national vital statistics data from 1990 to 2015

BP Outside of Clinic May Better Predict Outcomes in Black Patients

Higher systolic blood pressure measured with ambulatory monitoring tied to cardiovascular events, mortality

1971 to 2017 Saw 32 Drinking Water Hepatitis A Outbreaks

The last four reported hepatitis A outbreaks during 1995 to 2009 were due to individual water systems

January 2019 Briefing – Geriatrics

Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for January 2019. This roundup includes the latest...

Diabetes Outcomes Similar Regardless of Primary Provider

No difference in outcomes seen with care by physician, nurse practitioner, physician assistant

Hospitalized Pneumonia Patients Often Get Excess Antibiotics

Vast majority of excess treatment occurs with antibiotics prescribed at discharge

More Sports Experience May Reduce Impact of Concussions

Among youth with concussion history, more years of experience tied to quicker functional recovery

Burden of New-Onset A-Fib Considerable After TAVI, AVR

Odds of in-hospital mortality increased in TAVI, AVR hospitalization with new-onset atrial fibrillation

Black-White Cancer Mortality Gap Decreasing in Some Age Groups

Cancer deaths rates decreasing faster for black men and women vs. white men and women in U.S.

Energy Drinks Prolong QTc Interval, Elevate Blood Pressure

Findings seen among young, healthy volunteers randomly assigned to energy drinks or placebo

Increased Screen Time in Preschool Tied to Worse Inattention

Odds increased for reporting clinically significant externalizing problems, inattention problems

Daratumumab Cuts Risk for Progression in Multiple Myeloma

Adding daratumumab to lenalidomide + dexamethasone beneficial for newly diagnosed multiple myeloma

E-Cigarette Aerosol Exposure Tied to Asthma Symptoms

Findings seen among youth reporting asthma diagnosis, secondhand exposure to e-cigarette aerosols

Six Prognostic Factors ID’d for Invasive Disease After DCIS

Six significant factors include African-American race, premenopausal status, detection by palpation

Parity, Risk for Breast Cancer Studied for BRCA1/2 Carriers

Higher risk seen in uniparous BRCA1 carriers, parous BRCA2 carriers; breastfeeding cuts risk in BRCA1

Measles Outbreak Triggers Sharp Rise in Demand for Vaccine

More than 50 confirmed cases of measles, 11 suspected cases reported in Clark County, Washington, this year

Topical Immunotx for Actinic Keratosis May Prevent Cancer

Fewer patients treated with calcipotriol plus 5-FU developed SCC on treated face, scalp within three years

Many Older Patients With AML Not Receiving Active Treatment

No active treatment more likely with older age, lower household income, unmarried status, comorbidities

Patient Factors May Predict Opioid Use After Discharge

Certain factors, such as anxiety, associated with greater opioid use in the month after major surgery

Heroin Overdose ED Visits Decreased From 2017 to 2018

Decreases not consistent across states, with significant increases in Illinois, Indiana, Utah

Daily Cannabis Use More Common in Distressed Individuals

But use increasing among those with and without past-month serious psychological distress

In Severe, Asymptomatic Aortic Stenosis, Early Surgery May Help

Patients undergoing aortic valve replacement within a year of diagnosis appear to benefit most

Weight Loss Surgery May Not Relieve Acid Reflux

Symptoms return in half of patients undergoing long-term follow-up after gastric bypass

Assay Aids Anticoagulant Dosing of Obese Patients for Bariatric Sx

Thrombin generation assay may allow more accurate determination of anticoagulation adequacy

Opioid Prescribing, New Persistent Use Down After Childbirth

Strongest modifiable factor linked to new persistent use after delivery was filling Rx before delivery

Breast Cancer Diagnosis Delays Seen With High-Deductible Health Plans

Delays observed in first breast imaging, biopsy, incident early-stage breast cancer diagnosis, chemo

Single-Dose Brachytherapy Effective for Prostate Cancer

Two-year and three-year biochemical progression-free survival rate of 100 percent for low-risk disease

Coronary Artery Calcium Levels in Middle Age Tied to LV Function

Greater change in CAC score during follow-up linked to higher LV mass index in blacks, but not whites