OCT Imaging Needle Can Detect Blood Vessels in Neurosurgery

OCT probe integrated into standard brain biopsy needle IDs vessels with high sensitivity, specificity

Increase Seen in Amphetamine, Opioid Use in Pregnant Women

Increase in amphetamine-, opioid-related deliveries disproportionate between rural vs. urban counties

Total Fertility Rates Vary by State

Total fertility rate for U.S. 16 percent less than number needed to replace population

Recent Nasal Preps Less Effective Than Injected Vax for Flu in Kids

Quadrivalent live attenuated flu vaccine less effective than inactivated vaccine for influenza A/H1N1pdm09

Ertugliflozin Seems Safe, Effective for Type 2 Diabetes Treatment

Improvements seen in HbA1c, fasting glucose, body weight, blood pressure over two years

Outcomes of Importance ID’d for Peritoneal Dialysis Patients

PD-related infection, mortality, fatigue are highest-ranked outcomes for patients, caregivers

Low Vitamin D Tied to Risk for Renal Hyperfiltration in Healthy Adults

Severe deficiency linked to increased prevalence of RHF in population with normal renal function

FDA Investigating Paclitaxel-Coated Balloons, Paclitaxel-Eluting Stents

Investigation triggered by meta-analysis showing possible increased mortality in PAD patients at 2 years

No Asthma Benefit Seen With n3PUFA in Overweight Teens

Overweight/obese teens, young adults taking supplements do not have improved asthma control

Likelihood of Engaging in Choking Game Higher in Troubled Teens

History of depression, conduct disorders in teens associated with participating in choking game

Pregnancy-Adapted Algorithm Avoids Diagnostic Imaging for PE

Suspected pulmonary embolism safely ruled out in some pregnant women with diagnostic algorithm

Young Child Goes to ED for Medicine Poisoning Every 10 Minutes

Safe medicine storage in the home needs to begin well before infants are on the move

Stress Test-Based Physiological Age May Be Superior Mortality Predictor

Physiological age based on exercise stress testing performance better predictor than chronological age

Shifting Pattern Seen for Primary Care Office Visits

Primary care physician visits down, but visits to nurse practitioners, physician assistants up

Artificial Intelligence Can Use Routine ECGs to ID Heart Disease

Those with positive AI screen four times more likely to develop future ventricular dysfunction

Obesity Linked to Lower Gray Matter Brain Volume

Combination of overall obesity and central obesity linked to lowest gray matter volume

Rituximab Beneficial in Secondary Progressive MS

Treatment with rituximab linked to lower Expanded Disability Status Scale score, delayed progression

Sex Differences Seen in Pursuit of Interventional Cardiology Career

Factors negatively influencing women are largely related to the culture of the subspecialty

EMS Treatment for Possible Heart Attack Varies by Sex

Women less likely to receive aspirin, resuscitation, ambulance transport with lights and siren

More Than Two-Thirds of Drug OD Deaths in 2017 Involved Opioids

Significant increases seen in death rates involving synthetic opioids in 15 of 20 states from 2013 to 2017

AHA: Nearly Half of U.S. Adults Have Cardiovascular Disease

Forty-six percent of U.S. adults have hypertension

Intensive BP Treatment Does Not Reduce Dementia Risk

But drop seen in risk for MCI and combined rate of cognitive impairment, probable dementia

Texting Intervention Engages Patients After Joint Arthroplasty

Patient outcomes improved compared with traditional perioperative education

Cancer Risk Modestly Elevated With Chronic Kidney Disease

Lower eGFR linked to elevated cancer risk relative to eGFR of 90 to 104 mL/min

Knee Pain Not Tied to Activity Levels in Knee Osteoarthritis

Neither inverted KOOS-pain nor P4 pain scale tied to physical activity

Model Can Predict Survival in Nonmetastatic Prostate Cancer

Model demonstrated good discrimination for 15-year prostate cancer-specific mortality in validation cohorts

Targeted Hep C Testing Misses High Number of Cases in Prisons

Findings based on birth cohort, risk-based testing versus opt-out testing in prison system

U.S. Food Supply May Be at Risk Due to Government Shutdown

Number of routine food inspections performed by the FDA dropped sharply

AI Technology IDs Genetic Diseases by Analyzing Facial Photos

DeepGestalt technology better than doctors at identifying a range of genetic syndromes

Functional Milestones Identified for Persons With Down Syndrome

Most maintain personal hygiene by age 13, work independently by 20; 34 percent live independently

Complications Higher Than Expected for Invasive Lung Tests

Complication rates for invasive lung diagnostic procedures higher than those seen in clinical trials

Most Nurses Unsatisfied With Hospitals’ End-of-Life Care

The nurse practice environment was the best predictor of poor-quality end-of-life care

Mandated Neonatal Abstinence Reporting Helps Quantify Cases

Five of six states with mandatory reporting receive case reports within 30 days of diagnosis

Off-Label Uses in Dermatology Often Missing From Compendia

Only 30.7 percent of 238 treatments used to treat 22 dermatologic conditions listed in compendia

Gender Gap Seen in Accessing Alcohol Treatment With Cirrhosis

Women less likely to be treated than men; treatment visit, medication tied to improved one-year outcomes

Measles Outbreak Prompts Public Emergency in Washington State

23 measles cases confirmed and two more suspected cases under investigation

Testosterone Therapy in Hypogonadism Can Prevent Progression to T2DM

Men with prediabetes, hypogonadism achieved normal glucose regulation with TTh

Mumps Causes Quarantine of Over 2,200 Immigrant Detainees

25-day quarantine affects facilities in Pine Prairie, Louisiana, and Aurora, Colorado

Restrictive, Obstructive Lung Disease Linked to Dementia Risk

Associations seen for both Alzheimer's disease-related dementia and cerebrovascular etiologies

For Teen Girls, Depression May Predict Subsequent Alcohol Use

Depression severity predicts increased likelihood of alcohol use; link for reverse pathway inconsistent

Chemo-Radiation Combo Tied to Higher Survival in Peds Hodgkin

Five-year overall survival higher in patients who receive combined tx than those treated with chemo alone

Employment, Earning Losses Noted After Cardiovascular Events

Fewer patients admitted to hospital for MI, cardiac arrest, stroke working at three years postevent

Temporary Impairment in HRQOL After Teen Sports Concussion

Worse cognitive HRQOL and clinically meaningful impairment in school and overall HRQOL observed

Incident Concussion 5.1 Percent Per Season for Youth Football

Risk increased for youth with depression or history of concussion

More Americans Reporting Less Than Six Hours Sleep Per Night

The number of Hispanics, blacks getting short sleep is growing at a fast rate

Variation in Revascularization for Asymptomatic SIHD Unexplained

Consistent benefit observed for patients with stable ischemic heart disease managed by revascularization

Hand Hygiene Compliance Low Among EMS Providers

Use of hand rub or hand wash seen in 3 percent before, 29 percent after patient encounters

2003 to 2015 Saw Increase in Outpatient Benzodiazepine Use

Fourfold increase seen in rate of coprescribing with opioids; twofold increase with other sedating meds

Recommendations Issued for HSCT in Multiple Myeloma

Autologous stem cell transplant remains essential component of MM therapy in eligible patients

Mental Health Issues Have Risen in Teens, Young Adults

Rates of depressive episodes, serious psychological distress, suicide-related outcomes have increased

Tramadol May Up Mortality Risk in Osteoarthritis Patients

Findings for those initially prescribed tramadol compared with commonly prescribed NSAIDs

Impact of Fructose Varies With Energy Control, Food Source

Harmful effects for sugar-sweetened beverages when excess energy from sugar added to diet

Statin Therapy Reduces Risk for Diabetic Retinopathy in T2DM

Reduced risk, slowed progression of retinopathy for Taiwanese patients with type 2 diabetes, dyslipidemia

Fewer Than 5 Percent of Thyroid Surgery Patients Readmitted

Majority of readmissions occur within seven days of discharge and one-fourth within two days

Screening Donated Blood for Zika Not Cost-Effective

Universal mini-pool nucleic acid testing only during high mosquito activity cost-effective in Puerto Rico

Personalized Tx May Extend Life in CKD With Small Renal Tumors

Routine partial nephrectomy yielded longest life expectancy in patients with normal renal function

HPV Ups Cervical Cancer Risk, Even With No Cellular Signs

HPV-16/18 confers strong future risk, particularly in women younger than 30 years

Delayed School Start Shows Benefits for Teens

Longer sleep time tied to better grades, some improvements in attendance

Fruit, Vegetable Intake Very Low in Hemodialysis Population

Higher consumption of fruit and vegetables linked to lower risk for all-cause, non-CVD mortality

NOACs Recommended as First-Line Prevention of Stroke in A-Fib

Updated guidelines also emphasize weight loss for overweight, obese patients with atrial fibrillation

Suicide Incidence Up in Autism Spectrum Disorder 2013 to 2017

Difference driven by suicide among women, which was more than threefold higher

ACC: Dietary Cholesterol Ups Cardiovascular Disease Risk

Findings show dose-response increase in risk for cardiovascular disease, all-cause mortality

AAOS: Underweight Status Increases Shoulder Arthroplasty Complications

Physicians, health care systems should pay more attention to this 'extremely at-risk population'

Waiting Room Tool Aids Patient-Physician Communication

Tool helps patients to prepare questions and prioritize concerns prior to seeing primary care doctor

New BP Goals Could Prevent 3 Million CVD Events Over 10 Years

Maintaining ACC/AHA goals would result in fewer events than current BP levels, prior guideline goals

Flu Vaccination Safe for Hospitalized Patients

With vaccination, risks reduced for readmission, outpatient visits, fever, clinical evaluations for infection

Costs Higher for Those With Comorbid Noncommunicable Diseases

Health expenditure greater for person with two diseases simultaneously than for the diseases separately

In-Hospital Morbidity, Mortality Up With Flu in Heart Failure

Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury

Low-Income Women Lack Menstrual Hygiene Supplies

One in five low-income women in St. Louis cannot afford products on a monthly basis

Appalachia, Western States Have Highest Hep C Prevalence

Nine states account for more than 50 percent of all hepatitis C virus infections

Medication Treatment for Substance Abuse Up in Facilities

2007 to 2016 saw increase in use of medication treatment, reaching 36.1 percent in 2016

ASA: Flu-Like Illness Linked to Increased Risk for Stroke

Second study shows patients more likely to have ILI within 30 days preceding cervical artery dissection

Bone Health in Older Adults Not Improved by High-Dose Vitamin D

25(OH)D concentration increases with supplements, but no difference in BMD changes among three doses

Fried Chicken, Fish Linked to All-Cause, Cardiovascular Death

For postmenopausal women, mortality risk increased with one serving fried chicken/fish per week

Guidelines Developed for Polymyxin Antibiotic Use

Polymyxin B recommended for routine use in invasive infections; colistin preferred for lower UTI

Short Regimen Noninferior for Rifampin-Resistant Tuberculosis

Short regimen of nine to 11 months noninferior to 20-month regimen following WHO guidelines

Overlapping Orthopedic Surgery Noninferior for Patient Safety

Reduced odds of perioperative complications seen for overlapping surgery versus nonoverlapping surgery

Bone Indices on CT Scan Predict Fracture Risk in Older Adults

Peripheral CT indices address risk for fracture contributed by changes in bone microarchitecture

Increase in Brand-Name Drug Cost Mainly Due to Existing Drugs

Rising costs of oral, injectable generic and specialty drugs mostly driven by new product entry

Meta-Analysis: Botulinum A Tops Placebo for Chronic Migraine

Frequency of chronic migraines significantly reduced after three months; QoL improved

Prevalence of Knee OA Lower With Menopausal Hormone Therapy

Odds ratio for knee osteoarthritis was 0.7 in MHT group versus non-MHT group in multivariable model

CDC: Weight, Waist Size, BMI Increased for Many U.S. Adults

1999-2000 to 2015-2016 saw increase in mean weight, waist circumference, BMI for many subgroups

Opioid Prescribing Patterns Vary for Pediatric Patients

Geographic region, race, age, payment method associated with differences in opioid prescribing

Oral Hepatoselective Glucokinase Activator Promising in T2DM

Clinically significant and sustained reduction in glycated hemoglobin was observed with TTP399

Aerobic Exercise Tied to Better Cognition at All Ages

Effect seen as young as 20 years, although the effect is greater with increasing age

Home-Based Program Achieves Hypertension Control

Program uses Bluetooth-enabled monitoring, patient coaching by nurse practitioners and pharmacists

Sugary Drinks Tied to Cardiovascular Disease Mortality

Comparing extreme categories of consumption, SSB linked to increased CVD mortality, cancer mortality

AAP: Nasal Spray Vaccine Against Flu Acceptable in 2019 to 2020

Based on current data, AAP Board of Directors says either injection or nasal spray vaccination OK

Four-to-Seven-Day Opioid Rx Likely Sufficient for Acute Pain Treatment

No more than one in five patients who filled an opioid analgesic prescription obtained a refill

Core Language Skill Stable From Infancy to Adolescence

Consistency in core language skill is stable through childhood in typically, atypically developing children

Drug Repurposing May Provide More Psychiatric Tx Options

Three drug classes tied to lower rates of self-harm and psychiatric stays with serious mental illness

Smartphone App Can Detect Early Signs of Opioid Overdose

App has high sensitivity, specificity for opioid-induced central apnea, respiratory depression

Rx Opioids Up Pneumonia Risk in Patients With, Without HIV

Risk greatest with higher-dose opioids and opioids with immunosuppressive properties

Coronary Artery Calcium May Help Predict CVD in South Asians

CAC incidence similar in South Asian men versus white, black, Latino men; higher than Chinese

FDA Approves Drugs for Treatment of Two Rare Blood Diseases

Elzonris approved to treat BPDCN; Ultomiris approved for paroxysmal nocturnal hemoglobinuria

Review Highlights Lack of Tx Options for Prurigo Nodularis

Researchers call for more randomized controlled trials to investigate systemic treatments

Symptom Combos Suggesting Laryngeal Cancer Identified

10 features of laryngeal cancer with which patients presented in year before diagnosis identified

Depressive Symptoms Higher During Internal Medicine Internship

Faculty feedback, learning experience in inpatient rotations, work hours tied to change in symptoms

Cognitive Scores After Kidney Transplant Tied to Frailty

Cognitive function first improved then declined 1 to 4 years after transplant in frail recipients

ACC: Antibacterial Envelope Can Reduce CIED Infections

Incidence of major cardiac implantable electronic device infections significantly lower with envelope

Average of 283,000 Children Have Sports-Related TBIs/Year

From 2010 to 2016, average of 283,000 children sought care in EDs for SRR-TBIs

CDC: 228 Measles Cases Already in 2019

Number of cases in the United States so far this year getting close to the total number for all of 2018

Risk of Sudden Death in Epilepsy Can Decline Over Time

Those with a low risk for SUDEP generally remain in this categorization during three years of tracking

Less Deep Sleep in Elderly Tied to Alzheimer Disease Markers

Poor-quality sleep in later life could be a noninvasive marker for deteriorating brain health

Racial Differences ID’d in Some Biomarkers of Alzheimer’s Disease

African-Americans have lower mean CSF concentration of total tau, phosphorylated tau181

Sex Differences ID’d in Response to Glioblastoma Treatment

Standard therapy more effective for female versus male patients with glioblastoma

High Levels of Activity, Motor Ability Linked to Better Cognition

Findings seen in older adults; independent correlations remained for those with Alzheimer disease

Complications, Costs Up With Cardiac Sx in Opioid Use Disorder

No increased risk of mortality, but increase in incidence of major complications

FDA Panel Has Tie Vote on New Type 1 Diabetes Drug

Zynquista is a once-daily pill meant to help type 1 diabetes patients manage their blood glucose levels

FDA Receives an ‘F’ in Tobacco Prevention Report Card

American Lung Association releases State of Tobacco Control 2019 report

Adverse Birth Outcomes Up With Medically Assisted Reproduction

But risks are mainly attributable to factors other than medically assisted reproductive treatment

Time to Breast Cancer Surgery Delayed for Non-Hispanic Blacks

Racial differences in TTS did not explain racial differences in overall survival with breast-conserving sx

Less Invasive Method Safely IDs Epilepsy Surgical Candidates

Stereoelectroencephalography has better outcomes than subdural electrode implants in some cases

Head of National Cancer Institute Named Acting FDA Commissioner

Current commissioner, Scott Gottlieb, will be stepping down in April

Hospitalization for Upper GI Bleed Highest With Rivaroxaban

Upper gastrointestinal bleeding hospitalization risk lower for anticoagulant tx with PPI cotherapy

Presence of Antiphospholipid Antibodies Tied to First-Time MI

With validation, findings may impact management, outcomes of high-risk patients

No Increased Fall Risk With HTN Treatment in Older Women

Lower incidence rate ratios found for women with treated controlled hypertension, treated uncontrolled HTN

Exercise Can Consistently Lower Blood Pressure

Reductions in BP from exercise comparable but not as great as from medications

Hemochromatosis Mutation Linked to Other Morbidity

Higher rates of at least one incident-linked condition seen in men, women with HFE p.C282Y homozygosity

Mental, Behavior, Developmental Disorders Up With Low-Income

Children in lower- versus higher-income households more often diagnosed with MBDDs

Elevated Risk for Lung CA in Lung Transplant Recipients Explored

13-fold increased risk found in native lung for those receiving single lung transplant

Mandibular Contour Surgery Training System Beneficial

Improvements in clinical surgery time, accuracy with use of intraoral MCS training system

Prophylaxis for Gonococcal Eye Infections in Newborns Advised

USPSTF reaffirms use of antibiotic ointment to prevent gonococcal ophthalmia neonatorum

Psychopathology in Adulthood Up With Child Lead Exposure

Higher childhood blood lead levels linked to increase in general psychopathology

Antiepileptic Drugs Not Tied to Dementia Risk

No increased overall risk found, but levetiracetam generic brands tied to higher dementia risk

Intervention Promotes Better Conversations With Cancer Patients

But communication quality-improvement intervention does not improve patient outcomes

Parent Perception of E-Cig Safety Varies With Smoking Habits

Most who smoke cigarettes and e-cigs have smoke-free home policies; fewer have vape-free policies

CDC: Acute Flaccid Myelitis Cases Appear to Have Peaked for 2018

As of Nov. 30, 134 cases of AFM have been confirmed in 33 states

Persistent Opioid Use High in Head, Neck Cancer Patients

Opioid use before treatment, tobacco use are risk factors for ongoing opioid use

Fewer Complications Found With Hybrid Surgery for Esophageal Cancer

Incidence of intraoperative, postoperative complications lower in resectable esophageal cancer

School Nutrition Programs Slow BMI Gains in Children

Promoting healthier eating in middle school more effective than adding physical activity

Dermatologists’ Rx for Antibiotics Dropped From 2008 to 2016

However, rising use of antibiotics after dermatologic surgical visits is concerning

Drug Use-Associated Infective Endocarditis Up 2007 to 2017

More than 12-fold increase in DUA-IE hospitalizations and valve surgeries during 2007 to 2017

Having Children Tied to Higher Risk for Cardiovascular Disease

Significant link identified, with nonlinear J-shaped dose-response relationship for increasing parity

FDA Approves First Generic Version of Advair for Asthma, COPD

Medication approved to treat children aged 4 or older with asthma, adults with asthma or COPD

Few Patients With Type 1 Diabetes Meeting HbA1c Goals

Glycemic control not better in 2010 to 2018, despite more use of insulin pumps, continuous monitoring

Oncologists Have Low Awareness of LGBTQ Issues

However, oncologists overwhelmingly interested in learning more

Machine-Learning Models Allow Early Detection of Sepsis in NICU

Models using EHR data from infants in NICU can detect sepsis hours before clinical signs are apparent

CDC: 2000 to 2017 Saw Increase in Mortality Due to Dementia

Age-adjusted death rate was 66.7 deaths per 100,000 U.S. population in 2017

Diet Quality in Midlife Not Linked to Later Risk for Dementia

No significant difference in incidence rates for dementia according to measures of diet quality

Results of Pediatric Genomic Epilepsy Tests Often Reclassified

Over 30 percent of pediatric patients with genetic dx, undiagnosed conditions had results reclassified

Seniors Still Report Barriers to Hearing Care Services

Difficulties accessing hearing care services seen particularly in older Americans with lower incomes

USPSTF Affirms Guidance for Hep B Screening at First Prenatal Visit

Evidence convincing that universal prenatal screening reduces perinatal transmission of HBV

More Comorbidities, Lower Mortality for Holocaust Survivors

Mean age at death significantly higher for survivors versus controls

Adoption of Advanced Health IT Capabilities Inconsistent

Degree of EHR standardization strongest predictor of health information technology adoption

Initiative Can Cut Gender Gap in Medical School Faculty Salaries

Overall mean salary gap by gender decreased from −2.6 to −1.9 percent after a decade

Mindfulness, Stress Linked to Menopausal Symptoms

Link between mindfulness and symptoms more robust in women experiencing higher stress

Death at 10 Years Similar With Bilateral-, Single-Artery CABG

No difference seen in rate of death from any cause at 10 years in intention-to-treat analysis

Paclitaxel Exposure in Vascular Device Not Linked to Mortality

No deaths thought to be related to use of paclitaxel drug-coated balloons for vascular procedures in PAD

Initiative Tied to Decreased Racial Inequity in Breastfeeding

Compliance with Ten Steps program linked to increased breastfeeding in African-Americans

ASCO: Guidelines Released for Early Detection, Treatment of CRC

Stratified guidelines emphasize optimal detection methods and treatments of colorectal cancer

FDA Approves New Generic Valsartan to Ease Shortage

Certain lots of valsartan recalled due to contamination with trace amounts of nitrosamine

Pembrolizumab Promising for Metastatic Head, Neck SCC

Prolongs survival among patients with recurrent, metastatic head and neck squamous cell carcinoma

Limiting Social Media May Improve Psychological Well-Being

Limiting exposure to 30 minutes per day cut loneliness and depression in undergraduates

Measles Outbreak in New York State Largest in Recent History

There has been an increase in measles cases across the United States and worldwide

Childhood Hodgkin Lymphoma Survivors at Risk for Later Cancers

Survivors have 14-fold increased risk for developing a solid subsequent malignant neoplasm

High Symptom Burden in Elderly Linked to Adverse Outcomes

Higher symptom count seen with increasing age and for women versus men

Incorrect Prescribing Alerts Common for Psychotropic Meds

One-third with electronic Rx system that provides alerts believe system provides incorrect warnings

Universal Vaccination for MenB at College Entry Not Cost-Effective

Incremental cost per quality-adjusted life-year gained $13.8 million under societal perspective

Wait Times Have Improved in VA Health Care System

Wait times similar to private sector in 2014 but shorter overall and in some specialties in 2017

Blood Conservation Safe, Effective During Heart Surgery

Intraoperative autologous donation strategy leads to improved outcomes

Assessment Tools Aid Risk Planning at Nursing Homes

Residents with heart failure have higher rates of hospitalization, death, health instability

Daily Cannabis Use May Up Risk for Developing Psychotic Disorder

Daily cannabis use, especially high-potency types, linked to increased odds of psychotic disorder

‘Brain Vital Signs’ Detect Concussion-Related Changes

Six brainwave metrics can detect even subclinical changes in nonconcussed hockey players

Stillbirth Risk Up With High Serum Bile Acids in Pregnancy

Higher risk of stillbirth with serum bile acids ≥100 µmol/L in intrahepatic cholestasis of pregnancy

ASH: Ibrutinib Tops Bendamustine + Rituximab for CLL

Improved progression-free survival with ibrutinib for older adults with untreated CLL

Use of Diabetes Monitoring Tests in Primary Care Suboptimal

Less than 60 percent of patients with diabetes given HbA1c, lipid profile tests in preceding 12 months

Long Work Hours Tied to Poor Glycemic Control in T2DM

Findings seen in young male, but not female, Japanese workers with type 2 diabetes mellitus

Myelodysplastic Syndrome/AML Risk Increased After Chemo

Since 2000, risks for therapy-related myelodysplastic syndrome, AML up after chemo for solid cancers

Accidental IV Dislodgement Reported to Be Very Common

Top 3 causes were confused patient, removal of catheter by patient, tape or securement loose

Fecal Occult Blood Test May Improve CRC Outcomes in Some

For men with left-sided tumors, those undergoing screening had lower N, M categories, higher survival

Risk for Breast Cancer Increased With False-Positive Screening Result

Increased risk for screen-detected and interval breast cancer persists for 12 years after false-positive result

Management of MS in Pregnancy Reviewed in U.K. Guideline

Pros and cons of continuing treatment throughout pregnancy should be discussed individually

9/11 Responders May Have Higher Head, Neck Cancer Risk

Authors call for ongoing monitoring, treatment of those initially exposed

Assay Aids Anticoagulant Dosing of Obese Patients for Bariatric Sx

Thrombin generation assay may allow more accurate determination of anticoagulation adequacy

2011 to 2015 Saw Increase in Psychiatric ED Visits for Youth

Largest increases in emergency department visits seen for teens, African-Americans, Hispanic patients

Complex Dosing, Polypharmacy Common With Interstitial Lung Disease

Patients receiving systemic corticosteroids are at high risk for drug-disease interactions

Children With Poorly Controlled Asthma Suffer Academically

Latino and black children have poorer academic outcomes than non-Latino whites

Hypnotherapy Beats Education for Relief of IBS Symptoms

Group, individual hypnotherapy both effective; group hypnotherapy noninferior to individual tx

Outcomes Poorer for Medicaid Beneficiaries With STEMI

Rates of revascularization lower, in-hospital mortality higher for Medicaid versus privately insured

Medical Marketing Has Increased in Past 20 Years

Considerable increase seen from 1997 through 2016, especially in direct-to-consumer advertising

Risk for MCI Up With Progressive Cerebral Small Vessel Disease

Patients with hypertension with progressive cSVD have increased risk for mild cognitive impairment

A-Fib Risk Up for Antidepressant Users, but Higher Before Tx

Antidepressant treatment linked to threefold increased risk during first month; link decreased over year

Updated Guidelines Developed for Diagnosing, Treating Influenza

Rapid molecular assays should be used to improve diagnosis; antivirals should begin as soon as possible

Radiographic Knee Osteoarthritis Tied to Increased Risk for Death

Risk higher for cardiovascular disease, diabetes, renal mortality; lower risk for cancer mortality

Expanded Recall Announced for Ibuprofen Oral Suspension Drops

Higher levels of ibuprofen concentration found in some units may cause harm to infants

Evidence Lacking for Benefit of Surgery for Vertebral Fractures

No significant benefit with percutaneous vertebroplasty over placebo for acutely painful VF

Jury Finds Roundup a Major Contributor to Man’s Cancer

Landmark verdict could impact hundreds of other similar lawsuits

Induction for Late-Term Pregnancies at 41 Weeks Tied to Small Benefits

Study could not show noninferiority of expectant management; outcomes good with both strategies

Bronchiolitis Hospitalization in Infancy Predicts More Admissions

Higher risk seen for future admissions by age 5; link strongest for asthma, wheezing admissions

Structured Family-Centered Peds Rounds Improve Patient Safety

Forty percent decrease seen in harmful errors; decrease also in nonpreventable adverse events

Case Description Can Reliably Define Acute Flaccid Myelitis

Differences between patients with AFM, other diagnoses include asymmetry of weakness

Nine Cases of Wound Botulism ID’d in Injection Drug Users

All patients used injection drugs; seven reported using black tar heroin and six practiced skin popping

Home Monitoring of Lung Function Feasible in Teens With Duchenne

Peak flow meter handheld device useful for adolescents with Duchenne muscular dystrophy

Achieving Healthy Diet From Sustainable Food Feasible

Global adoption of healthy reference diet would reduce morbidity, environmental degradation

FDA Announces Safety Monitoring Measures for the Essure Device

Measures include having women in the postmarket surveillance study followed for five years, not three

Oculomotor Response to Head Impacts Studied in Youth Football

Near point of convergence measured in players during a single high school football season

More High-Value Care Associated With Receipt of Primary Care

Increasing investment in primary care may improve value in the U.S. health care system

Public Health Interventions Could Cut Global Burden of Hepatitis C

Package of prevention, screening, treatments could avert 15.1 million new infections versus 2015

Improved Genetic Risk Score Aids Type 1 Diabetes Classification

Revised risk score also improves newborn screening versus HLA genotyping alone