Flu Vaccination in High-Risk Groups May Reduce CV Events

Hospitalized patients at high risk who are vaccinated have lower rates of MI, TIA, cardiac arrest, death

Moderna Charging Much More for COVID-19 Vaccine Than Others

Vaccine currently in phase 3 trials; company confident it will be available by the end of the year

Longer Bisphosphonate Drug Holiday May Up Fracture Risk

For those with previous vertebral fracture, major osteoporotic fractures increased with holidays >12 months

Overscreening for Cancer Common Among Older Adults

Findings seen across cancer types, particularly for women living in U.S. metropolitan areas

COVID-19 Tied to Higher Risk for Large Vessel Occlusion Strokes

However, no association seen between COVID-19 and small vessel occlusion stroke

Life Expectancy 78.60 Years for U.S. Population for 2009-2011

Highest life expectancy at birth for Hispanic women, non-Hispanic white women, Hispanic men

Expanded Obstetric Comorbidity Score Developed, Validated

Score improved prediction of severe maternal morbidity, nontransfusion severe maternal morbidity

Short-Term Risk for Below-Knee Amputation Not Increased With SGLT2i

Risk for below-knee amputation not increased versus DPP-4 inhibitor use in patients with type 2 diabetes

Telestroke Consultations Down During COVID-19 Pandemic

From March through April 2020, Black patients were significantly less likely to present with stroke

SARS-CoV-2 Antibodies Detected in 13.7 Percent of NYC HCPs

Previous positive PCR test, suspicion of exposure associated with seropositivity

Scientists Call for Broader Use of Faster COVID-19 Tests

Currently, most tests rely on complex laboratory procedures, such as polymerase chain reaction

Western Diet Tied to Adult Acne

Large survey shows diets high in fatty, sugary foods and drinks and milk associated with current acne

Gastric Cancer Incidence in Those ≥50 Differs by Race/Ethnicity

Incidence of noncardia gastric adenocarcinoma higher in nonwhites than in non-Hispanic whites

ICU Beds Lacking in Low-Income Neighborhoods Across the U.S.

Authors say policies facilitating hospital coordination urgently needed to mitigate the effects of COVID-19

ASCRS Updates Guidelines on Surgery for Crohn Disease

Surgery may be considered for those with inadequate response to, nonadherence with medical therapy

Diabetes-Related Lower-Limb Amputations Up in Older Adults

Absolute rates for amputation among Medicare beneficiaries highest in oldest old, blacks, men

AHA: Cannabis May Have Adverse Cardiovascular Effects

No indication of cardiovascular benefits found; more research needed to further understand adverse effects

Relapse Rates Lower With Ofatumumab in Multiple Sclerosis

Annualized relapse rates lower for ofatumumab versus teriflunomide in two identical phase 3 trials

Vitamin D/Calcium Reduces Benign Paroxysmal Positional Vertigo

Annual recurrence rate reduced with vitamin D, calcium supplementation versus observation

‘Freeze-All’ Strategy Not Superior to Fresh Embryo Transfer in IVF

Chances of pregnancy no higher with frozen over fresh embryo transfer

Skin Conditions Common in Older Adults

Authors urge whole-body skin examinations for geriatric patients

CDC: More American Indian, Alaska Natives in Fair, Poor Health

18.9 percent of AIAN adults have a disability in large MSAs versus 12.9 percent in rural areas

ED Visits Decreased in Five States From January Through April 2020

Increase in admission rates from the ED seen during same period, with largest relative increase in NY

Early Use of IL-6 Inhibitors May Improve COVID-19 Outcomes

Mortality, risk for intubation lower with IL6ri use in severe COVID-19 stage IIB versus stage III

Johnson & Johnson Makes $1 Billion Vaccine Deal

Company has said it will offer doses at a not-for-profit cost to provide global access to the vaccine

Experimental COVID-19 Vaccine Shows Encouraging Results

One study revealed that 56 people made high levels of antibodies with no adverse side effects

Seven States Join Pact to Speed COVID-19 Testing

Bipartisan plan illustrates just how bad testing delays are across the country

Subcutaneous ICD Noninferior to Transvenous ICD

Findings seen for patients with indication for implantable cardioverter defibrillator but no indication for pacing

Education May Affect β-Amyloid Burden in Alzheimer Disease

Findings seen in two cohorts with parental history of sporadic AD, autosomal dominant AD

CDC Describes 238 Confirmed Cases of Acute Flaccid Myelitis

Median patient age was 5.3 years; 86 percent of patients had onset during August to November

Health Plans Not Implementing Prior Authorization Reforms

Findings based on American Medical Association survey of practicing physicians' experiences

Improved Screenings by Ob-Gyns May Help Detect Heart Problems

Women seen at outpatient ob-gyn clinics largely unaware of heart risks and symptoms; screenings may help

Bisphenol A Linked to More Asthma Symptoms in Young Boys

Study shows exposure to bisphenol A is associated with more asthma symptoms in low-income boys

CV Meds Underused in Hispanics With Peripheral Artery Disease

For all classes of cardiovascular medications, lowest use seen for individuals of Mexican background

Risk for Cardiovascular Disease Up for Women With PCOS

After stratification by age, no increased CVD risk for women with PCOS observed after age 50 years

Rheumatoid Arthritis Linked to Lower Risk for Incident T2DM

Risk for incident type 2 diabetes lower compared with four comparison groups, including HTN, OA, PsA

Study Looks at Optimal Strategy for Reopening Schools in U.K.

Second study from Australia shows low SARS-CoV-2 transmission rates in educational setting

ATS Issues Guide for Diagnosing Hypersensitivity Pneumonitis

Systematic approach developed for diagnosis of nonfibrotic, fibrotic HP in interstitial lung disease

COVID-19 Case Fatality Rate 29 Percent in Multiple Myeloma Patients

Increased odds of adverse outcomes seen for Hispanic/Latinos, African-American Blacks versus white patients

Worldwide Burden of Gout Increased From 1990 to 2017

Men had higher global point prevalence estimates for gout; prevalence higher in older age groups

AI-Enabled ECG Can Identify Left Ventricular Systolic Dysfunction

LVSD identified with AUC of 0.89, accuracy of 85.9 percent; sensitivity and specificity of 74, 87 percent

Trump’s Plan Limits Free Nursing Home COVID-19 Tests

Although nursing homes house small percentage of the population, as many as 40 percent of COVID-19 deaths occur there

President Says Medicare Should Expand Telehealth Services

Medicare has already expanded its coverage for telehealth due to the COVID-19 pandemic

Most Studies Still Fail to Analyze Data by Sex

However, women are significantly better represented in clinical trials

Malpractice Fears, Patient Safety Drive Skin Doctors to Order Extra Tests

In a survey, dermatopathologists cite patient safety, malpractice fears as reason to use extra patient services

Number of Newly ID’d U.S. Patients With Cancer Dropped During COVID-19

Decrease of 46.4 percent found for newly identified patients with six common cancer types during pandemic

WTC Responders With Impaired Cognition Have Brain Changes

Another study IDs plasma proteins associated with PTSD, MCI, both in World Trade Center responders

Probiotics Not Recommended for Most Digestive Conditions

Probiotics for Crohn disease, ulcerative colitis, IBS, C. difficile should be used only in context of clinical trial

Long-Term Negative Thinking Tied to Alzheimer Risk

Association seen between negative thinking, cognitive decline, neuroimaging markers

Remote Weight-Loss Program Optimized to Cut Costs, Maximize Results

New method yielded best results, lower costs for overweight adults assigned to weight-loss programs

Program Cuts Outpatient Antibiotic Rx for Peds Respiratory Infections

Distance learning program includes online tutorials, webinars; video vignettes; individualized feedback

USPSTF Still Advises Against Carotid Artery Stenosis Screening

Harms of screening for asymptomatic carotid artery stenosis outweigh benefits in general population

Vitamin D3 Does Not Reduce Depression Incidence, Recurrence

Incidence and recurrence of depression, change in mood scores did not differ from placebo for adults ≥50

β2-Agonists Improve Nonaerobic Athletic Performance

Specifically, sprint and strength performance were enhanced with use of β2-agonists

Burnout High Among Nonphysician Frontline Health Care Workers

Findings based on survey of COVID-19 frontline workers surveyed at a tertiary care center in Japan

Risk for Positive COVID-19 Test Up for Health Care Workers

Risk increased for frontline health care workers compared with the general community

July 2020 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for July 2020. This roundup includes the latest...

July 2020 Briefing – Pain Management

Here are what the editors at HealthDay consider to be the most important developments in Pain Management for July 2020. This roundup includes the...

38 Percent of Older Adults in U.S. Not Ready for Video Doctor Visits

Telephone visits may reach more patients, but 20 percent of older adults not ready for telephone visits

July 2020 Briefing – Psychiatry

Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for July 2020. This roundup includes the latest...

July 2020 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for July 2020. This roundup includes the latest...

July 2020 Briefing – Allergy

Here are what the editors at HealthDay consider to be the most important developments in Allergy for July 2020. This roundup includes the latest...

July 2020 Briefing – Pulmonology

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for July 2020. This roundup includes the latest...

Cannabidiol Studied as Potential Treatment for Cannabis Use Disorder

Abstinence from cannabis increased with cannabidiol 400-mg, 800-mg doses compared with placebo

July 2020 Briefing – Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for July 2020. This roundup includes the latest...

July 2020 Briefing – Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for July 2020. This roundup includes the latest...

Canakinumab Explored as Therapy for Large-Joint Osteoarthritis

Exploratory analysis reveals total hip/knee replacement rate reduced with canakinumab versus placebo

July 2020 Briefing – Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for July 2020. This roundup includes the latest...

July 2020 Briefing – Surgery

Here are what the editors at HealthDay consider to be the most important developments in Surgery for July 2020. This roundup includes the latest...

Early-Life Adversity Associated With Accelerated Biological Aging

Links vary by adversity type; threat-related early-life adversity tied to accelerated pubertal development

July 2020 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for July 2020. This roundup includes...

July 2020 Briefing – Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for July 2020. This roundup includes the latest...

Botox Injections May Ease Depression

An FDA database revealed that people who receive Botox injections report less depression

July 2020 Briefing – Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for July 2020. This roundup includes the...

July 2020 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for July 2020. This roundup includes the...

Cost-Related Rx Nonadherence Highest in Young U.S. Women

One in four women report cost-related nonadherence versus one in seven men

July 2020 Briefing – Gastroenterology

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for July 2020. This roundup includes the latest...

July 2020 Briefing – Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for July 2020. This roundup includes the...

Short Video May Lower Parent Interest in Antibiotics for Child

Even bigger impact seen among parents with highest baseline interest in antibiotics

July 2020 Briefing – HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for July 2020. This roundup includes...

July 2020 Briefing – Emergency Medicine

Here are what the editors at HealthDay consider to be the most important developments in Emergency Medicine for July 2020. This roundup includes the...

Mortality Risk Increased With Pulmonary Vascular Resistance of ≥2.2

For patients referred for RHC, risk for mortality, heart failure up with PVR of ≥2.2 Wood units

July 2020 Briefing – Infectious Disease

Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for July 2020. This roundup includes the...

July 2020 Briefing – Otolaryngology

Here are what the editors at HealthDay consider to be the most important developments in Otolaryngology for July 2020. This roundup includes the latest...

Risk for Acute Cerebrovascular Events Low in COVID-19 Patients

In hospitalized patients with COVID-19, 2.4 percent had confirmed ischemic stroke, 0.9 percent had ICH

July 2020 Briefing – Neurology

Here are what the editors at HealthDay consider to be the most important developments in Neurology for July 2020. This roundup includes the latest...

July 2020 Briefing – Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for July 2020. This roundup includes the latest...

Obesity Ups Risk for Intubation, Death With COVID-19 in Adults <65

Risk highest for those with class 3 obesity; link mainly seen in adults younger than 65 years of age

July 2020 Briefing – Nursing

Here are what the editors at HealthDay consider to be the most important developments in Nursing for July 2020. This roundup includes the latest...

July 2020 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for July 2020. This roundup includes the latest...

Cardiorespiratory Fitness Linked to Outcomes After A-Fib Ablation

Arrhythmia recurrence rate, mortality significantly lower in those with higher cardiorespiratory fitness

July 2020 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for July 2020. This roundup...

July 2020 Briefing – Radiology

Here are what the editors at HealthDay consider to be the most important developments in Radiology for July 2020. This roundup includes the latest...

Adverse Experiences More Common Among Children Raised by Grandparents

ADHD also more common for preschool-age, school-age children in grandparent-headed households

July 2020 Briefing – Hematology & Oncology

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for July 2020. This roundup includes...

July 2020 Briefing – Anesthesiology

Here are what the editors at HealthDay consider to be the most important developments in Anesthesiology for July 2020. This roundup includes the latest...

More Than One in Three Stroke Survivors Have Uncontrolled HTN

80.4 percent of stroke survivors take antihypertensive medications, most commonly ACEi, ARB

July 2020 Briefing – Ophthalmology

Here are what the editors at HealthDay consider to be the most important developments in Ophthalmology for July 2020. This roundup includes the latest...

July 2020 Briefing – Cosmetic Surgery

Here are what the editors at HealthDay consider to be the most important developments in Cosmetic Surgery for July 2020. This roundup includes the...

Guidelines Indicate Breastfeeding Is Safe After Maternal Anesthesia

There is no need to discard breast milk after anesthesia; opioid sparing preferred for breastfeeding moms

July 2020 Briefing – Orthopedics

Here are what the editors at HealthDay consider to be the most important developments in Orthopedics for July 2020. This roundup includes the latest...

July 2020 Briefing – Geriatrics

Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for July 2020. This roundup includes the latest...

Survivors of Adolescent, Young Adult ALL May Suffer Late Effects

Estimated 10-year cumulative incidence high for subsequent endocrine disease, cardiac disease

Bacterial, Fungal Coinfection Uncommon in COVID-19 Patients

Ninety-eight percent of patients received antibiotics at any point during COVID-19 hospitalization

Telemedicine Use Explodes During COVID-19 Pandemic

Two experts spoke with HD Live! about telemedicine's growth, best practices, outlook for the future

U.S. Puts Up Another $2.1 Billion for Potential COVID-19 Vaccine

GlaxoSmithKline and Sanofi Pasteur will supply 100 million doses of its experimental vaccine to the U.S.

Plenty of COVID-19 Vaccine Coming, Fauci Says

To combat the surging pandemic, Fauci is calling on all Americans to practice social distancing and wearing masks

Pandemic Causing Increased Anxiety Among MS Patients

Anxiety increased compared with healthy controls and previous patient survey one year before COVID-19

COVID-19 Testing Needed Every Two Days to Reopen Colleges

Frequency of screening is more important than the accuracy of the test

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

P-tau217 Shows Promise as Biomarker for Alzheimer Disease

Plasma P-tau217 discriminated AD from other neurodegenerative diseases in three selected cohorts

Dual Sensory Impairment Ups Dementia Risk

Findings compared with individual or no sensory impairment

Early Age at Menarche Tied to Frequent Menopausal Symptoms

Midlife body mass index may play important role in modifying this risk

Second BMD Measurement Not Beneficial for Identifying Hip Fracture

Second BMD assessment about three years after initial measure not linked to improved discrimination

Mortality Rates Highest for Infants Born to Teens Age 15 to 19

Rates highest for infants of non-Hispanic black teens versus infants of non-Hispanic white, Hispanic teens

Sex Differences in Income Vary With Proportion of Male Doctors

Sex difference in annual income lower in practices with 50 percent or less male physicians

Inflammation Tied to Thyroid Dysfunction With Psoriasis

Prevalence of thyroid dysfunction high with generalized pustular, erythrodermic psoriasis

Global Epidemiology of COVID-19 Reported for Prepandemic Era

101 clusters ID'd; transmission higher in non-health care occupational settings, community gatherings

Cinnamon Supplementation May Improve Blood Glucose Control

Findings support research on whether cinnamon can slow progression of prediabetes to type 2 diabetes

ACS Issues Updated Guideline for Cervical Cancer Screening

Screening, preferably with primary HPV testing, should start at age 25 and continue through age 65

Study IDs Which Women Benefit From DBT Versus Digital Mammography

Benefits of DBT seen in women with heterogeneously dense breasts, scattered fibroglandular density

Twelve Factors Account for About 40 Percent of Dementias

Actions to mitigate dementia risk include maintaining SBP of 130 mm Hg or less, using hearing aids

FDA Warns Companies Illegally Selling Hangover Cures

People should be wary of any products that claim to prevent, treat, mitigate, or cure diseases

Young Children Have Higher Amounts of SARS-CoV-2 RNA

Children younger than 5 years have lower median cycle threshold values compared with older children, adults

School Closures Linked to Decreased COVID-19 Incidence, Death

Associations were largest in states with low cumulative incidence of COVID-19 at time of school closure

Excessive Drinking Responsible for 255 Deaths Per Day in U.S.

In addition, 29 years of life lost per death in the United States each year from 2011 to 2015

Remdesivir Shortages Plague Some Hospitals, Pharmacists Say

One-third of pharmacists report that they do not have enough remdesivir to treat all eligible patients

Delayed Treatment of Upper Respiratory Tract Infections Tied to Hospitalization Risk

However, delayed antibiotic prescribing was used similarly between high- and low-risk patients

Teen HPV Vaccination Rates Suboptimal

Half of parents of unvaccinated teens have no intention to initiate the vaccine series

Chocolate Tied to Lower Coronary Artery Disease Risk

Moderate consumption once a week tied to lower risk for disease

Fibroid-Related QOL Better With Myomectomy for Uterine Fibroids

Mean score on health-related QOL domain of UFS-QOL higher than with uterine artery embolization

Nirsevimab Injection Cuts RSV-Linked Infections in Preemies

Maternal RSV fusion protein nanoparticle vaccine did not meet prespecified success criterion for efficacy

Most Gynecologic Cancer Therapy Not Tied to Higher COVID-19 Risk

Only recent immunotherapy use linked to death due to COVID-19 in gynecologic oncology patients

S. aureus Agr Virulence Tied to Atopic Dermatitis in Infants

Expression of functional Agr system in S. aureus needed for epidermal colonization in mice

Maternal Allergy, Asthma Traits Up Child Risk in Early Years

By the time the child is 6 years old, mother's and father's history present similar risk

Policy Guides Medical Marijuana Use at Pediatric Hospital

Eighty percent of pediatric patients seen by MMJ consultative service had an oncologic diagnosis

Risk for Heart Failure Increased for Women Taking β-Blockers

Difference of 4.6 percent found between women and men in rate of heart failure at presentation for ACS

Baloxavir Protects Household Contacts From Influenza

Percentage of patients in whom clinical influenza developed significantly lower in baloxavir group

Arthritis Patients Needing to Shelter in Place Require More Support

Survey finds many experiencing increased symptoms, less physical activity, emotional issues

COVID-19 Case Rates, Deaths Considerably Higher in Prisons

Case rate more than fivefold higher among prisoners versus U.S. population; death rate also higher

COVID-19-Related Symptoms Persist After Recovery

Only 12.6 percent of patients completely free of any COVID-19-related symptoms

Black Individuals at Increased Risk for SARS-CoV-2 Infection

Risk increased for infection and hospitalization, but not mortality, for Blacks versus non-Blacks

Adherence to Prophylaxis for EGFRi-Linked Rash Beneficial

Adherence to prophylaxis protocols tied to drop in interventions, toxicity-linked chemo interruptions

Glucose Levels Tied to Maternal Mortality Even Without Diabetes

Elevated A1c may predict maternal morbidity, death even in women without known prepregnancy DM

Viral Exposure Signature Predicts Hepatocellular Carcinoma

Signature can identify hepatocellular carcinoma patients before clinical diagnosis

Patterns Changing for Heart Disorder Hospitalizations in Canada

Rates up for acquired valvular heart disease, vascular cognitive impairment, and congenital heart disease

CDC: 2017 to 2018 Saw Decline in Teen Birth Rates Across States

Declines seen among non-Hispanic white, non-Hispanic black, Hispanic teenagers aged 15 to 19

Incidence of Takotsubo Cardiomyopathy Up During COVID-19

Incidence proportion 7.8 percent during March, April 2020 versus 1.5 to 1.8 percent before pandemic

COVID-19 Explored in Kidney Recipients, Hemodialysis Patients

Many kidney recipients with COVID-19 do not need to be hospitalized; deaths up for those on hemodialysis

Drop Seen in Rate of Sports and Recreation-Related TBI in Children

2012 to 2018 saw decrease in SSR TBI ED visits for children, mainly due to drop in contact sports-linked TBI

More Than One in Four Seniors Reported Falling in Past Year

In 2018, 27.5 percent of older adults reported falling at least once; 10.2 percent reported injury from a fall

Children Seem Not to Be Driving SARS-COV-2 Transmission

Children mainly infected in familial clusters, and transmission lower than expected in schools

WHO to Lead Investigation of COVID-19 Pandemic Origins

Agency acknowledged on Thursday that the new coronavirus can linger in small airborne droplets indoors

Gilead Presents Additional Data on Efficacy of Remdesivir for COVID-19

Pharma company says there is further evidence remdesivir may reduce deaths, hasten recovery

Emphasizing Severity of COVID-19 Important for Teen Behaviors

Greater social responsibility correlated with more disinfecting, news monitoring, less hoarding

Risk for COVID-19 Increased for Adults Taking PPIs

Dose-response relationship observed; risk up 3.67-fold for those using PPIs up to twice daily

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Fetal, Early-Life Exposures May Impact Young Adult Bone Health

Specifically, maternal smoking and breastfeeding tied to fracture risk in young adulthood

Low Back Pain Also May Resolve in Some After Hip Replacement

Authors say careful evaluation of hip, back pain can help surgeons decide order of hip, spine intervention

Odds of Surgery Lower for Black Patients With Esophageal Cancer

Black race independently confers reduced odds of surgery; mortality higher for those without surgery

Higher Vitamin C, Carotenoid Intake May Lower Risk for T2DM

And, rate of type 2 diabetes lower for participants in highest versus lowest category of whole grain intake

2008 to 2018 Saw Increase in Shingles Vaccination in Over 60s

Women equally as likely as men to have received vaccine; coverage highest for non-poor, those with higher education

Half of Individuals With MI at Age 50 or Younger Are Smokers

Smoking cessation linked to reduced risk for all-cause and cardiovascular mortality in this population

Multifactor Program Does Not Cut Serious Fall Injuries in Elderly

Rate of first adjudicated serious fall injury not reduced for intervention versus enhanced usual care

Newborn Iodine Status Not Tied to Congenital Hypothyroidism

But among infants treated in neonatal ICU, cases had significantly higher blood iodine levels than controls

CDC Updates Info on COVID-19 Cases at Meat, Poultry Processing Facilities

COVID-19 confirmed in 16,233 workers at 239 facilities in 23 states through May 31, 2020

Spectrum of Neurological Disorders Linked to SARS-CoV-2

Neurological manifestations include inflammatory CNS syndromes, encephalopathies, ischemic stroke

Serum Neurofilament Light May Help Assess Concussion, TBI

NfL shows promise as serum biomarker for traumatic brain injury, sports-related concussion

Physically Demanding Jobs May Raise Risk for Knee Osteoarthritis

Occupational lifting, kneeling, climbing, squatting, standing versus sedentary work linked to knee OA

COVID-19 Pandemic Exacerbates Mental Health Issues

Don Mordecai, M.D., talks with HD Live! about mental health consequences, in particular for frontline health care workers

Higher Rates of Pain, Bleeding Found With Essure Birth Control Device

In 2018, Essure maker Bayer pulled the device from the U.S. market due to concerns about side effects

Electronic Health Records Fail to Detect Many Medication Errors

Though broadly used in U.S. hospitals, EHRs fail to detect up to one-third of medication errors

Nemolizumab Beats Placebo for Reduction of Pruritus in Eczema

VAS score reduction greater at week 16 for addition of nemolizumab versus placebo to topical agents

Sick Days Up for Some Essential Workers During COVID-19

Significant increases seen in personal care and service, health care support, production occupations

Rising Number of People Report Anxiety, Depression During COVID-19

Since pandemic began, number of people seeking mental health screening, showing symptoms up substantially

Dairy Does Not Protect Against Bone Loss During Menopause Transition

Similarly, no association seen between dairy food intake and risk for fractures

Huntington Disease Brain Changes ID’d 24 Years Before Symptoms

Authors say this might represent the optimal time to treat Huntington disease with emerging drugs

2010 Healthy, Hunger-Free Kids Act Tied to Drop in Childhood Obesity

The stronger nutrition standards for school meals and snacks should be maintained, the authors say

Long-Acting Drug Targeting Capsid Protein Promising for HIV

Reduction of viral load seen nine days after dose; sustained plasma exposure seen for more than six months

Multisystem Inflammatory Syndrome in Children Profiled

Two reports describe characteristics of MIS-C seen in U.S. pediatric health centers, New York state

Interruption of Sitting May Cut Acute Postprandial Response

Interruption of prolonged sitting with light exercise reduced postprandial insulin and glucose levels

Statin Use May Cut All-Cause, CVD Mortality in Those 75 and Older

Reductions in risk seen for all-cause, CV mortality and composite of atherosclerotic CV events

February to March 2020 Saw Surge in Hydroxychloroquine Rx

Number of patients receiving hydroxychloroquine, chloroquine prescriptions climbed across the U.S.

American Cancer Society Updates HPV Vaccination Guidelines

Vaccination should be routinely offered at age 9 to 12 years; catch-up vaccination recommended through age 26

11 Dengue Fever Cases Confirmed in Florida Keys

All 11 cases of the mosquito-borne disease have been in Key Largo

Employers Can Refuse to Provide Birth Control Coverage: U.S Supreme Court

Lower courts had previously blocked changes to a requirement in the Affordable Care Act

U.S. Launches Suicide Prevention Campaign

REACH campaign urges people to reach out to others and acknowledge daily stress in people's lives

Upadacitinib Beats Methotrexate in Early Rheumatoid Arthritis

Significantly better clinical, radiographic, patient-reported outcomes seen with upadacitinib

Suspected Plague Case Reported in China

While largely eradicated in China, there are still occasional cases in the country

Efforts to Reduce New HIV Infections in Children Faltering

New estimates show that 150,000 children were newly infected with HIV in 2019

Chilblains in Recent Case Series Not Tied to COVID-19 Infection

SARS-CoV-2 undetected by PCR on nasopharyngeal swabs and in biopsy samples of skin in 31 patients

Complementary, Alternative Medicine Use Increasing for MS

Ninefold increase observed in likelihood of patients speaking to their neurologist about CAM use

Excessive Sugar Tied to Fat Deposits Around Heart, Other Organs

These higher-risk fat deposits linked to greater risk for heart disease and diabetes

Social Distancing Effective for Mitigating COVID-19 Spread

Decreased mobility correlated strongly with reduced COVID-19 case growth rates across U.S. counties

Review: Pre/Probiotics May Be Useful for Depression, Anxiety

All seven studies demonstrated significant improvements in one or more of the outcomes measured

Genetic Variant Identified for Adult-Onset Hearing Loss

12 nucleotide in-frame deletion in RIPOR2 identified as highly penetrant cause of hearing loss

Acute Ischemic Stroke Risk Higher With COVID-19 Than Influenza

Higher risk remains even when adjusting for demographic and clinical features

Oral Corticosteroid Bursts Carry Risk for Severe Adverse Events

Highest rates of adverse events seen within first month after initiating short course of oral steroids

Early Breast Cancer Screening Benefits Childhood Cancer Survivors

Early initiation of breast cancer screening with MRI may reduce breast cancer mortality by more than half

USPSTF Advises Annual Low-Dose CT Lung Screening for High-Risk Individuals

Annual CT screening recommended for those aged 50 to 80 years at high risk due to smoking history