ABCDE Bundle Can Reduce Ventilation Time for ICU Patients

Awakening and breathing coordination, delirium monitoring/management, early mobility are key

May 2020 Briefing – Neurology

Here are what the editors at HealthDay consider to be the most important developments in Neurology for May 2020. This roundup includes the latest...

May 2020 Briefing – Nephrology

Here are what the editors at HealthDay consider to be the most important developments in Nephrology for May 2020. This roundup includes the latest...

Insulin Resistance May Add to Racial Disparity in Breast Cancer Prognosis

Tumors from black women with invasive breast cancer have higher expression of the insulin receptor

May 2020 Briefing – Nursing

Here are what the editors at HealthDay consider to be the most important developments in Nursing for May 2020. This roundup includes the latest...

May 2020 Briefing – Pathology

Here are what the editors at HealthDay consider to be the most important developments in Pathology for May 2020. This roundup includes the latest...

Significant Drop Seen in Type A Aortic Dissection After COVID-19

Monthly surgical case volume of aortic dissection declined 76.5 percent; volumes low in March, April

May 2020 Briefing – OBGYN & Women’s Health

Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for May 2020. This roundup...

May 2020 Briefing – Radiology

Here are what the editors at HealthDay consider to be the most important developments in Radiology for May 2020. This roundup includes the latest...

Dextrose Injections Aid Knee Osteoarthritis Pain

Benefits include reduced pain, improved function, better quality of life

May 2020 Briefing – Hematology & Oncology

Here are what the editors at HealthDay consider to be the most important developments in Hematology & Oncology for May 2020. This roundup includes...

May 2020 Briefing – Anesthesiology

Here are what the editors at HealthDay consider to be the most important developments in Anesthesiology for May 2020. This roundup includes the latest...

Thyroid Dysfunction in Pregnancy Overdiagnosed, Overtreated

In most women with elevated TSH who did not start treatment, repeat measurement was ≤4.00 mIU/L

May 2020 Briefing – Ophthalmology

Here are what the editors at HealthDay consider to be the most important developments in Ophthalmology for May 2020. This roundup includes the latest...

May 2020 Briefing – Cosmetic Surgery

Here are what the editors at HealthDay consider to be the most important developments in Cosmetic Surgery for May 2020. This roundup includes the...

Italian Health Care Workers’ Mental Health Suffering During COVID-19

Symptoms of posttraumatic stress disorder, depression, anxiety, and insomnia all common

May 2020 Briefing – Orthopedics

Here are what the editors at HealthDay consider to be the most important developments in Orthopedics for May 2020. This roundup includes the latest...

May 2020 Briefing – Geriatrics

Here are what the editors at HealthDay consider to be the most important developments in Geriatrics for May 2020. This roundup includes the latest...

Parents Overestimate, Underestimate Children’s Mobile Phone Use

Among children aged 3 to 5 years with their own device, average daily usage was 115.3 minutes per day

May 2020 Briefing – Pediatrics

Here are what the editors at HealthDay consider to be the most important developments in Pediatrics for May 2020. This roundup includes the latest...

May 2020 Briefing – Pain Management

Here are what the editors at HealthDay consider to be the most important developments in Pain Management for May 2020. This roundup includes the...

COVID-19 May Drive Increase in Childhood Obesity Rates

Lack of physical activity associated with extended school closings could increase rates by 2.4 percent

May 2020 Briefing – Psychiatry

Here are what the editors at HealthDay consider to be the most important developments in Psychiatry for May 2020. This roundup includes the latest...

May 2020 Briefing – Pharmacy

Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for May 2020. This roundup includes the latest...

May 2020 Briefing – Allergy

Here are what the editors at HealthDay consider to be the most important developments in Allergy for May 2020. This roundup includes the latest...

May 2020 Briefing – Pulmonology

Here are what the editors at HealthDay consider to be the most important developments in Pulmonology for May 2020. This roundup includes the latest...

May 2020 Briefing – Cardiology

Here are what the editors at HealthDay consider to be the most important developments in Cardiology for May 2020. This roundup includes the latest...

May 2020 Briefing – Rheumatology

Here are what the editors at HealthDay consider to be the most important developments in Rheumatology for May 2020. This roundup includes the latest...

May 2020 Briefing – Dermatology

Here are what the editors at HealthDay consider to be the most important developments in Dermatology for May 2020. This roundup includes the latest...

May 2020 Briefing – Surgery

Here are what the editors at HealthDay consider to be the most important developments in Surgery for May 2020. This roundup includes the latest...

May 2020 Briefing – Diabetes & Endocrinology

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for May 2020. This roundup includes...

May 2020 Briefing – Urology

Here are what the editors at HealthDay consider to be the most important developments in Urology for May 2020. This roundup includes the latest...

May 2020 Briefing – Family Practice

Here are what the editors at HealthDay consider to be the most important developments in Family Practice for May 2020. This roundup includes the...

May 2020 Briefing – Internal Medicine

Here are what the editors at HealthDay consider to be the most important developments in Internal Medicine for May 2020. This roundup includes the...

May 2020 Briefing – Gastroenterology

Here are what the editors at HealthDay consider to be the most important developments in Gastroenterology for May 2020. This roundup includes the latest...

May 2020 Briefing – Critical Care

Here are what the editors at HealthDay consider to be the most important developments in Critical Care for May 2020. This roundup includes the...

ASCO: Mortality High for Cancer Patients With COVID-19

Factors linked to 30-day mortality include age, male sex, smoking status, comorbidities, active cancer

May 2020 Briefing – HIV & AIDS

Here are what the editors at HealthDay consider to be the most important developments in HIV & AIDS for May 2020. This roundup includes...

May 2020 Briefing – Emergency Medicine

Here are what the editors at HealthDay consider to be the most important developments in Emergency Medicine for May 2020. This roundup includes the...

Radiation Oncology Clinic Visits Down Due to COVID-19

Patient volume decreased despite vast majority of practices adopting enhanced safety practices

May 2020 Briefing – Infectious Disease

Here are what the editors at HealthDay consider to be the most important developments in Infectious Disease for May 2020. This roundup includes the...

May 2020 Briefing – Otolaryngology

Here are what the editors at HealthDay consider to be the most important developments in Otolaryngology for May 2020. This roundup includes the latest...

ASCO: Relugolix Superior to Leuprolide in Advanced Prostate Cancer

And, enzalutamide improves median overall survival in nonmetastatic, castration-resistant prostate cancer

Success More Than 50 Percent for Second Child With Fertility Treatment

Chances range from 51 to 88 percent depending on use of frozen versus fresh embryos

Burden of Severe COVID-19 High in California, Washington State

Length of stay was 9.3 days for survivors; probability high for ICU admission, mortality

Inequity Found in Access to Transplant With Universal Health Care

Patient factors including socioeconomic status account for much variation in kidney transplant access

Five-Day Course of Remdesivir Beneficial in Severe COVID-19

No significant difference seen in five-, 10-day course for severe COVID-19 without mechanical ventilation

1990 to 2017 Saw Increase in Prevalence, Incidence of Psoriasis

In addition, global burden of suffering related to psoriasis increased, with increases in YLDs, DALYs

Outcomes Equal for AYA Hodgkin Therapy at Peds, Adult Centers

Treatment strategies differ, but outcomes equivalent among adolescent, young adult Hodgkin patients

Infection Risk Up in Month After CAR T-Cell Immunotherapy

Infection rates increase in patients with ALL aged ≤26 years in first month, then decrease at days 29 to 90

Remdesivir Use Growing Globally in COVID-19 Patients

Yet, most physicians believe it is only moderately effective, better used earlier than official guidelines recommend

VA Slashes Use of Hydroxychloroquine to Treat COVID-19 Patients

Prescribing reduced to just three prescriptions in the last week as new research highlights possible dangers

Metformin Recalled Due to Potential Cancer-Causing Chemical

Recall is for all lots of metformin hydrochloride extended-release tablets 500 mg from Apotex

Deferment of Elective Surgeries Due to COVID-19 Will Have Lasting Impact

Cumulative backlog includes more than 1 million surgeries at two years after end of elective surgery deferment

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Multiple Sclerosis Tied to Higher Risk for CVD, Cerebrovascular Disease

MS associated with a 3.5-fold higher risk for mortality, 1.5-fold higher risk for cardiovascular mortality

Globally, Women Less Likely to Develop Heart Disease Than Men

Rates of primary prevention higher in women, but secondary prevention efforts higher in men

Exposure to Urban Air Pollution May Up Risk of Multiple Sclerosis

Adjusted risk 29 percent higher among those residing in more urbanized areas

AAOS: Opioid Prescribing Down for Minor Ortho Injuries in Youth

However, 54.3 percent of patients received at least one dose of opioid during ED or clinic visit

AAOS: QR Codes on Children’s Casts May Be Useful for Care Info

In many cases, scanning the code keeps patients from needing to contact the treating physician

Improving Glycemic Control May Also Aid COVID-19 Outcomes

Insulin infusion may reduce risk for severe disease in those with hyperglycemia and COVID-19

Spirituality May Have Protective Effect on QOL for Stroke Survivors

Spirituality may moderate link between care partner depressive symptoms and survivor psychological QOL

Disease-Modifying Drug Regimen May Offer Benefit in Heart Failure

Lower risk for cardiovascular death or hospital admission seen in HF with reduced ejection fraction

9.5 Percent Uninsured in U.S. From January Through June 2019

Overall, 13.7 percent of adults aged 18 to 64, 4.4 percent of children aged 0 to 17 were uninsured

Risk for Later Invasive Breast Cancer Up for Women With DCIS

Risks for invasive breast cancer, death from breast cancer higher for up to 20 years following diagnosis

Links Found Between Leaders of Medical Associations, Industry

Most leaders have ties to industry; considerable variation seen among 10 medical associations in U.S.

Genetic Data May Up Diagnostic Efficiency for Rheumatic Disease

Genetic Probability tool (G-PROB) calculates probability for diagnosis based on genetic risk scores

CV Toxicity Tied to Azithromycin and/or Hydroxychloroquine

Risk increased for prolonged QT and/or ventricular tachycardia, including torsades de pointes

Parents Facing Higher Levels of Stress During Pandemic

Pandemic-related stress also disproportionately impacting communities of color

Large U.S. Pharmacy Chains Played Role in Opioid Crisis, Lawsuit Claims

Lawsuit charges chains sold millions of pills in small communities, gave bonuses to pharmacists

CDC: Coronavirus Antibody Tests Still Not Accurate Enough

Too little is known about what the presence of antibodies means in terms of future immunity

Tooth Loss More Prevalent in Adults With Chronic Disease

Prevalence of edentulism, severe tooth loss ≥50 percent higher for adults with RA, asthma, diabetes

Early Informed Lung Cancer Patients Have Greater Survival Rates

Predicted survival time for patients who were unaware of their diagnosis was poor

Only One in Four U.S. Hospitals With ICUs Have Tele-ICU Services

Wide regional variation seen for availability of telehealth outpatient visits, tele-ICU services

Surgery Not Superior for Closed Displaced Humeral Shaft Fractures

Findings based on 12-month functional outcomes for surgery compared with functional bracing

AI Model Predicts Risk for Age-Related Macular Degeneration

Algorithm based on retinal photographs plus lifestyle (diet and smoking) and demographic data

African-Americans More Likely to Be Hospitalized With COVID-19

Odds of hospitalization increased 2.7-fold versus non-Hispanic whites after adjustment for age, sex, comorbidity

CBT Offers Some Benefits in Adults With Dissociative Seizures

CBT plus standardized medical care does not reduce monthly seizure frequency versus standardized medical care alone

Neuroimaging Features of COVID-19 Are Variable

But acute ischemic infarcts are a predominant finding among those with acute neurological symptoms

Benzodiazepines, Codispensed Opioids Common in Hemodialysis

Risk for mortality increased for those receiving short-acting benzodiazepines alone or with opioids

Palliative Care Linked to Fewer Readmissions for Heart Failure

Fewer readmissions, less mechanical ventilation seen with palliative care during heart failure admissions

Parents Struggling to Provide for Families During Pandemic

Hardships greatest for low-income, Hispanic, and black parents

Outcomes Similar After TAVR in Bicuspid, Tricuspid Anatomy

All-cause mortality, stroke comparable at 30 days, one year after transcatheter aortic valve replacement

Neurofilament Light Chain Levels Elevated After Repetitive TBI

Elevated exosomal, plasma levels of NfL also linked to chronic PCS, PTSD, depressive symptoms

New Medicare Benefit Would Limit Insulin Copays to $35 a Month

Benefit will be voluntary; Medicare recipients must pick an insurance plan that provides it

High Prevalence of Primary Aldosteronism Observed

Adjusted prevalence estimates of aldosteronism increase in parallel with hypertension severity

USPSTF: Little Evidence Interventions Prevent Illicit Drug Use in Youth

Current evidence inadequate for assessing balance of benefits, harms of interventions among youth

Primary Care Providers Report More Workplace Burnout, Anxiety

Providers who experience higher levels of anxiety, withdrawal more likely to report burnout

Air Filters Shown to Improve Breathing in Children With Asthma

Daily in-bedroom use of a PM2.5 filter results in significant improvement of airway mechanics

Right Ventricular Dilation Linked to Mortality in COVID-19

Right ventricular enlargement significantly linked to in-hospital mortality in multivariable analysis

Environmental Chemical Exposure Tied to Kidney Disease in the U.S.

Researchers identify link between seven chemicals and chronic kidney disease

Lasting Drop Seen in CRC Incidence, Death After Negative Colonoscopy

Reductions only seen for 10.1 to 17.4 years of follow-up after high-quality colonoscopy

Three Trajectories of Picky Eating Identified in Children

Membership in high picky-eating trajectory tied to higher child emotional lability, lower emotional regulation

Platinum Therapy May Up Survival in Pancreatic Cancer With DNA Repair Defects

PFS longer in pancreatic ductal adenocarcinoma with versus without homologous recombination deficiency

Placental Injury Seen in Pregnant Women With SARS-CoV-2

Higher rates of decidual arteriopathy, other maternal vascular malperfusion features observed

Adenovirus Type-5 Vectored COVID-19 Vaccine Shows Promise

ELISA antibodies and neutralizing antibodies increased at day 14, peaked at day 28

Hydroxychloroquine Plus Macrolides No Benefit in COVID-19

Hydroxychloroquine, chloroquine with or without macrolides linked to in-hospital mortality, arrhythmia

Remdesivir Beats Placebo for Time to COVID-19 Recovery

Researchers suggest antiviral agents in combination with other therapeutic approaches may further improve outcomes

WHO Suspends Testing of Hydroxychloroquine in COVID-19 Patients

In light of recent findings, hydroxychloroquine arm of WHO global study paused temporarily

Antiobesity Meds May Curb Weight Regain After RYGB

Statistical models suggest phentermine, topiramate, combination can slow, prevent weight regain

Delays in Cancer Surgery Due to COVID-19 Could Harm Survival

Per-patient delay of three or six months would result in an estimated 92,214 or 208,275 life-years lost

U.S. Offers $1.2 Billion to Drug Company for COVID-19 Vaccine Research

Deal will fund phase 3 clinical trial in the United States this summer with about 30,000 volunteers

Age, Sex, History of Diabetes Predict Intubation in COVID-19

Only factors independently associated with time to extubation are age and body mass index

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Weight in Adolescence Tied to Early-Onset Type 2 Diabetes

Higher risk for type 2 diabetes during young adult years tied to body mass index during adolescence

Biomechanical Footwear May Aid Knee Osteoarthritis Outcomes

While significant improvement seen across pain, function, stiffness scores, clinical impact remains uncertain

Updated Guidelines Issued for Management of Diverticulitis

CT scan is most appropriate initial imaging modality; lifestyle interventions can reduce risk

Clinical Genetic Testing for Autism Remains Very Low

Based on self-reported data, gap remains between guideline recommendations and clinical practice

ED Chest X-Ray Score Predicts COVID-19 Outcomes in Adults <50

CXR severity score ≥2 and obesity independent predictors of hospital admission

Cardiac Decompensation Seen in Children Following COVID-19

Cardiac decompensation occurred in conjunction with multisystem inflammatory syndrome in some children

Incidence of AMI Hospitalization Down During COVID-19

Decrease seen in incidence of STEMI, NSTEMI in Northern California during COVID-19 period versus pre-COVID-19

No SARS-CoV-2 ID’d in Asymptomatic Pregnant Women in Los Angeles

Among 80 asymptomatic pregnant women admitted to Cedars-Sinai Medical Center, none tested positive

Mobile Platform Useful for Treating Depression, Anxiety

Engagement with apps high; effects sustained for two months

Asthma Tied to Longer COVID-19 Intubation Time

However, asthma not associated with higher rates of acute respiratory distress syndrome, death

Musculoskeletal Malformations Up With Fluconazole in Pregnancy

But no increase seen in conotruncal malformations, oral clefts with use of oral fluconazole in first trimester

Factors Linked to COVID-19 In-Hospital Mortality ID’d in NYC

22 percent of patients critically ill; older age, chronic cardiac disease linked to higher in-hospital mortality

CDC: Live Poultry Linked to Salmonella Cases in 28 States

17 hospitalizations reported, but no deaths reported; children younger than 5 account for one-third of ill people

CDC Says Test All Newborns of Mothers With Confirmed, Suspected COVID-19

Newborns should be tested 24 hours after birth and, if the test is negative, be retested the next day

One-Year Mortality High Following ED Visit for Overdose

Mortality rates higher from unintentional overdose, suicide, and natural causes at one year

Rate of Stroke Low in Hospitalized Patients With COVID-19

Cryptogenic strokes more common, mortality higher in COVID-19 patients than in controls with stroke

Deaths From Alcohol, Drugs, Suicide Topped 150,000 in 2018

While there was a decrease in opioid overdose deaths, alcohol and suicide deaths increased

ACR Updates Guideline for Management of Gout

ULT strongly recommended for tophaceous gout, radiographic damage due to gout, gout flares

Clinical Performance of SARS-COV-2 Antibody Tests Varies

Sensitivity of both Abbot and EUROIMMUN serologic assays poor during first 14 days of symptoms

Risk for Autism Spectrum Disorder Up With Affected Aunt, Uncle

Rates of ASD higher for offspring of mothers or fathers with a sibling diagnosed with ASD

Higher Number of Pregnancy Losses Tied to Subsequent Type 2 Diabetes

Women who never achieve pregnancy have increased odds of T2DM versus ever-pregnant women with loss

Melanoma Risk From Biologic Therapy Remains Uncertain

Systematic literature review and meta-analysis reveal link to increased risk cannot be ruled out

Sex Differences ID’d in Prescription of Cardiovascular Meds

Women are less likely to be prescribed aspirin, statins, antihypertensive medications, including ACEIs

Review Highlights Neuropsychiatric Presentations of COVID-19

Evidence presented for delirium during COVID-19, post-illness neuropsychiatric consequences for SARS, MERS

CDC: Number of Births, General Fertility Rate in U.S. Down in 2019

General fertility rate for women aged 15 to 44, total fertility rate decreased to record lows in 2019

High BMI in Childhood May Up Risk for Bladder Cancer as Adult

Height inversely linked to bladder cancer, while excess BMI gain in childhood linked to increased risk

Multiple Genes Predispose Black Women to Breast Cancer

High risks for breast cancer associated with mutations in BRCA1, BRCA2, PALB2

Sales of Johnson’s Baby Powder Halted in U.S., Canada

Johnson & Johnson says talc-based powder is safe and will still be sold in other countries

Local-Stage Prostate Cancer Incidence Rates Continue to Drop

Rates of regional- and distant-stage prostate cancer increasing in the U.S. among men aged ≥50 years

Plasma NfL Level Tied to Risk for Disability in Multiple Sclerosis

High pNfL levels linked to increased adjusted rates of Expanded Disability Status Scale worsening

Decrease Seen in Child Vaccination Coverage During COVID-19

Up-to-date status for all recommended vaccines down to 49.7 percent among children aged 5 months

Some Children With COVID-19 Require Admission, PICU Care

Elevated CRP, procalcitonin, pro-BNP, platelet count -- but not obesity, asthma -- linked to PICU admission

Global Practice Guidelines Issued by International Society of Hypertension

Optimal, essential recommendations presented for lifestyle interventions, therapy in adults with HTN

Excessive Drinking Seen in Some Patients With Chronic Conditions

Findings based on data from 2.7 million adults seen in primary care for 26 common medical conditions

11.2 Percent of Pediatric Cancer Patients Positive for SARS-CoV-2

Rate of positivity 29.3 percent among screen- or symptom-positive patients; 2.5 percent in asymptomatic patients

Age, CRP Up Risk for Mortality in Diabetes With COVID-19

Insulin usage linked to poor prognosis; ACEI/ARB use did not impact clinical outcome in those with HTN

Odds of Pulmonary Embolism Up for Obese COVID-19 Patients

Odds of developing PE lower for COVID-19 patients taking statin therapy prior to admission

Spending on Primary Care Continues to Lag in the U.S.

Authors say increasing investment in primary care could slow future health care spending growth

Corticosteroids for IBD May Up Risk for Severe COVID-19

TNF antagonists not associated with severe COVID-19 in patients with inflammatory bowel disease

Hydroxychloroquine Does Not Improve COVID-19 Pneumonia Outcomes

Second study shows no benefit versus standard of care in probability of negative conversion by 28 days

28 Million-Plus Surgeries Could Be Canceled Due to COVID-19

About 45 weeks needed to clear surgery backlog if countries up surgical volume by 20 percent later

Factors ID’d for Positive SARS-CoV-2 Test Result in Primary Care

Sociodemographic risk factors include male sex, deprivation, population density, ethnicity, obesity

Cord Blood Does Not Improve Socialization Skills in Autism

Single CB infusion does not improve socialization skills or reduce symptoms for children with ASD

Burnout Comparable Between Millennial, Gen X Residents, Fellows

Length of medical-system exposure, not generational traits, contribute to burnout

Majority of Cancers Diagnosed Within Six Months of BI-RADS 3

Cancer yield 4.6 percent for women who underwent biopsy at time of lesion detection

Obesity Tied to Increased Risk for Progression to Severe COVID-19

Authors urge close monitoring, prompt treatment for obese patients with COVID-19

Mental Health Symptoms Up for Medics Dealing With COVID-19

Mean Symptom Checklist-90 score significantly higher for medical personnel responding to COVID-19

15 Percent of Pregnant Women With COVID-19 Experience Severe Disease

Nearly all of those with severe disease in case series were overweight or obese before pregnancy

CMS: Use ‘Extreme Caution’ in Reopening Nursing Homes

There have been more than 33,000 deaths due to coronavirus outbreaks in U.S. nursing homes

Higher Burden of Cardiovascular Risk Tied to Cognitive Decline

Also, higher CV risk associated with smaller volumes of hippocampus, gray matter, total brain on MRI

Higher Intake of Whole-Fat Dairy May Cut Metabolic Syndrome Risk

Similar associations found for hypertension, diabetes in large multinational cohort study

Yoga May Help Ease Depressive Symptoms

Findings seen in a literature review and meta-analysis for adults with diagnosed mental health disorders

Guidance Issued for Osteoporosis Management During COVID-19

Alternative methods for parenteral treatments include off-site clinics, home visit, self-injection

Statin, Aspirin Uptake Low With Peripheral Artery Disease, Stroke

Authors call for increased awareness of need for treatment with secondary preventive medications

Most Physicians Have Seen False-Negative COVID-19 Test Results

One in 10 physicians worldwide report seeing at least one case of COVID-19 reinfection

Sleep Problems in Infancy May Be Tied to Autism Diagnosis

Findings seen among children at risk for autism due to having a sibling with the condition

Use of Imaging to Assess Stroke Down in Early COVID-19 Epoch

Daily counts of patients who underwent imaging dropped from prepandemic to early-pandemic period

Hydroxychloroquine No Aid for COVID-Related Mortality

Hydroxychloroquine alone or with azithromycin associated with abnormal electrocardiogram findings

Co-Occurring Visual Impairment, Dementia Heighten Disability Risk

Links seen to mobility, self-care, household activity among older adults with either, both conditions

No Improvements Seen in Meeting AAP Vitamin D Intake Guidelines

Nonbreastfeeding infants more likely to meet the guidelines than breastfeeding infants

Cough May Not Appear in Young Children With COVID-19

Digestive tract infection appears common in children hospitalized with COVID-19 in China

Convalescent Plasma Appears Promising for Severe COVID-19

In series of 25 patients, 19 experienced improvement in clinical status by day 14; 11 were discharged

Experimental COVID-19 Vaccine Appears Safe, Triggers Immune Response

Findings from early-stage trial that started in March and included eight healthy people receiving two doses

Osteoporotic Fracture Risk Lower for DOAC Than Warfarin in A-Fib

No differences seen in fracture risk in head-to-head comparisons of direct oral anticoagulants

Fruit-, Veggie-Rich Diet May Soon Lower Markers for Cardiac Injury

Healthy eating during eight weeks tied to lower levels of markers for subclinical cardiac damage, strain

Post-AMI Home Health Care May Lower Risk for Readmission

Patients currently receiving home health care tend to be older, female, have underlying medical conditions

Regular Aspirin Use Tied to Lower Risk for Digestive Tract Cancers

Favorable effect increases with longer duration of use, and, for colorectal cancer, with increasing dose

Intensive Blood Pressure Control Tied to Lower Atrial Fibrillation Risk

Lowering systolic BP to <120 mm Hg lowers risk by 26 percent

Distracted Driving Laws Tied to Fewer Teen Crash Fatalities

Texting, handheld phone bans tied to fewer motor vehicle crash deaths involving drivers aged 16 to 19

T2DM Linked to Worse Cognitive Performance After Stroke

No significant difference found in cognitive function for those with impaired, normal fasting glucose levels

Early Diagnosis of Gestational Diabetes Leads to Less Weight Gain

Screening high-risk women for GDM in first trimester optimizes gestational weight gain

Autism in Childhood May Up Risk for Later Eating Disorders

Findings seen in longitudinal study of children followed from age 7 to 16 years

Addition of Atezolizumab May Aid in Metastatic Urothelial Cancer

Phase 3 trial shows prolonged progression-free survival for atezolizumab plus platinum-based chemo

Interferon-α2b May Shorten Viral Shedding Duration in COVID-19

Duration of elevated blood levels for inflammatory markers IL-6, C-reactive protein also reduced

ACP Advises Against Chloroquine, Hydroxychloroquine for COVID-19

Practice points based on lack of evidence supporting use as prophylaxis or treatment for COVID-19

FDA: Abbott Rapid COVID-19 Test Could Miss Infections

Research has suggested that the Abbott ID NOW point-of-care test may return false-negative results

NIH: Large-Scale Testing of Some COVID-19 Vaccines Could Start in July

About a dozen potential vaccines worldwide are in the initial stages of, or set to begin, testing in people

NIH Launches Trial of Hydroxychloroquine, Azithromycin for COVID-19

Trial will enroll 2,000 patients with SARS-COV-2 who have fever, cough, and/or shortness of breath

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Opioid-Related Deaths Less Likely Among Cancer Patients

Mortality lower despite common opioid prescriptions for cancer-related pain

Poll: One in Seven Older Adults Report Food Insecurity

Yet, very few are able to access government food benefits, including food stamps or home-delivered meals

Bowel Abnormalities Described in Inpatients With COVID-19

Bowel wall abnormalities identified on 31 percent of 42 CT scans, associated with ICU admission

Graduated Compression Stockings May Not Be Needed After Surgery

Low molecular weight heparin noninferior to LMWH plus GCS for preventing VTE after elective surgery

Guidance Issued for Acute Large Vessel CVA During COVID-19 Pandemic

Recommendations relate to prehospital care, pre-, intra-, postthrombectomy care

High Career Satisfaction Reported by Many Thoracic Surgeons

But 55.7 percent of cardiothoracic surgeons who responded report symptoms of burnout or depression

Risk for Inflammatory Bowel Disease, Celiac Disease Linked

Risk for celiac disease increased in patients with inflammatory bowel disease and vice versa

Meta-Analysis Links Smoking to COVID-19 Disease Progression

Risk for COVID-19 progression nearly double for smokers versus nonsmokers

Improvements Seen in Some Cognitive Domains With Aerobic Exercise

Middle-aged, older adults saw improvement after six-month aerobic exercise intervention

COVID-19 Fatality Rate High for Heart Transplant Recipients

Of 28 infected HT recipients, 79 percent admitted for treatment, 25 percent needed mechanical ventilation

Cannabis Smoking May Increase Risk for Fungal Infection

After adjustment for age, immunocompromised status, odds ratio of fungal infection was 3.5

Abnormalities Detected on Brain MRI of COVID-19 Patients in ICU

Acute findings reported for 44 percent of those with neurological symptoms who underwent brain MRI

Any Weight Loss Before Bariatric Surgery May Cut 30-Day Mortality

Further, 30-day mortality risk after bariatric surgery increases with higher preoperative body mass index

Kawasaki-Like Disease Incidence Up After Start of SARS-CoV-2

Children diagnosed after start of SARS-CoV-2 were older, had higher rate of cardiac involvement

Opt-Out Universal Hep C Screening in Emergency Dept Is Useful

47.8 percent of cases reactive to HIV antibody were among those born after 1965

Prevalence of Postpartum Depressive Symptoms 13.2 Percent

Overall, 79.1 percent of women reported being asked about depression during prenatal care visits

Sickness Presenteeism Common With Influenza-Like Illness

Most health care workers, non-HCWs continue to work when sick with ILI; more HCWs work with fever