Risk for heart failure and stroke particularly higher; risk for heart attack, atrial fibrillation moderately higher
Larger effects seen for people from lower-income households
Systolic, diastolic HTN independently predict composite outcome with thresholds of ≥140/90 or 130/80 mm Hg
Cyst classifier test is based on clinical and imaging features, genetic and biochemical markers
Pregnancies reduced in women taking isotretinoin since iPLEDGE initiation in 2006, but exposure persists
Pooled prevalence of preventable patient harm was 6 percent; 12 percent was severe, led to death
Cataracts found to be most commonly reported eye disorder affecting adults aged ≥45 years with diabetes
No reduction seen in individual-level nonmedical prescription opioid use from 2002 to 2014
Multiple breaches included inadequate hygiene, unsafe injection practices, poor cleaning, disinfection
Positron emission tomography used to track stages of β-amyloid accumulation in vivo
Continuous background pattern at six or 12 hours an independent predictor of good outcome
Drug found to be superior in maintaining proteinuria remission for up to 24 months
Higher hemorrhagic stroke risk seen for individuals with low-density lipoprotein cholesterol <70 mg/dL
With proper guidance, primary care physicians can screen, diagnose, and treat depression
Findings seen among patients with subcentimeter colorectal polyps receiving oral anticoagulants
Larger studies needed to further assess safety of intranasal sufentanil
Higher measures of subclinical myocardial damage, cardiac wall strain linked to new falls
Those with malignancy have higher long-term mortality but no difference in short-term outcomes
Inpatient portals used less by older and African-American patients versus younger, white patients
Leakage similar or lower for menstrual cups versus disposable pads or tampons
Exercise, lower vascular risk independently attenuate negative link for Aβ burden, cognitive decline
Judge said punitive award was too much and reduced it to $20 million
However, U.S. drug overdose death rate remains about seven times higher than a generation ago
Drug approved to treat patients with limited or no alternative antibacterial drugs to treat infection
Declarations of emergency typically spur increases in global attention and aid
Odds of postoperative versus preoperative relapse were not increased in unadjusted, adjusted analyses
Risk for death higher even with depression remission versus never experiencing depression
Odds of TNBC diagnosis increased for black, Hispanic, and younger women
Benefit-risk profile superior to vitamin K antagonists for early-stage chronic kidney disease
Young adult LDL ≥100 mg/dL tied to 64 percent increased risk for CHD, independent of later levels
Overall, 80.6 percent of current smokers, 84.3 percent of former smokers favor cutting nicotine
Findings seen in prespecified analysis; alirocumab did not increase risk for new diabetes
Cell-associated HIV DNA ID'd in CSF in nearly half of participants, tied to worse neurocognitive outcomes
Living donor versus deceased donor liver transplant also yields less resource utilization
Short-term cognitive behavioral therapy helpful for treating a range of internet addictions
Providing educational intervention in waiting room before pediatric provider visit may be beneficial
For family members, anxiety and depression scores were significantly better with flexible visitation policy
Compared with control states, decrease in sepsis mortality greater after implementation of regulations
However, 2000 to 2015 saw increased colorectal cancer incidence for ages 40 to 54
Age-adjusted unintentional injury death rate increased 40 percent
Number and proportion of entries attributable to parental drug use increased from 2000 to 2017
Residential exposure linked to AH, reduced HDL cholesterol for individuals living in multistory houses
Bone structure value determined by software tool significantly correlated with bone mineral density
BCPR less likely in races/ethnicities other than white
Findings seen in patients receiving etanercept for other autoimmune diseases
Diabetes, polyarticular gout, prior opioid use tied to increased risk for opioid prescription at discharge
Prescription opioids for postsurgical pain may lead to addiction that affects future pregnancies
Lower rates of firearm-related pediatric mortality seen in states with stricter gun laws
Thyroid cancer patients who perceive no choice about radioactive iodine report lower decision satisfaction
Risk for all-cause mortality lower for patients with practitioners with higher levels of empathy
For dual users, restrictive regulations may result in increased combustible cigarette use, lower e-cig use
Case raising fears that Ebola outbreak in Congo could make its way into Rwanda
Settlement the largest in U.S. history in a case involving an opioid medication
Dose-dependent relationship seen in a large national cohort of U.S. veterans
Obese patients have significantly more relapses on first-line treatment with IFN beta, glatiramer acetate
Negative effects on cognitive, motor outcomes seen from age 6 months persist to school age
Motor function increased significantly but not to degree considered a priori as clinically meaningful
Prescribing fewer tablets with education session further reduces opioid use
Risk for CVD events/all-cause mortality increased for TV viewing, not occupational sitting
Lower percentage of patients reported antibiotic use, received antibiotic prescriptions
Lost earnings of $94.4 billion reported in the United States in 2015
Peak level was significantly higher than the average during previous five influenza seasons
Condition is risk factor for benign prostatic hyperplasia, cardiovascular disease, dementia
U.S. teens, adults expected to lose about 15.46 million QALYs over 20 years due to uncontrolled asthma
Vascular events, infections, cancers account for 74.1 percent of high-severity misdiagnosis-related harms
Most common effects include agitation, tachycardia, drowsiness, vomiting, confusion
After speech and language examination, 62.6 percent of infants did not undergo surgical procedure
Laboratory tests confirm rabies in a cat that scratched two cast members
More than 80 percent of respondents reported presenteeism with 8.9 days lost productivity per year
Risk higher regardless of microvascular disease location or other blood vessel conditions
Findings also revealed low use of statins among patients with chronic kidney disease
PrEP awareness increased by 50 percent overall from 2014 to 2017; however, use is still low
No differences seen in post-training patient mortality, readmissions, or costs of care
Findings published from phase III trial of patients with moderate-to-severe acute postoperative pain
Even two years of clinical remission does not protect against bone erosions
Biases associate men with careers and surgery and women with family and family medicine
Vast majority of excess treatment occurs with antibiotics prescribed at discharge
Each point higher in social strain tied to greater loss in femoral neck, total hip, lumbar spine BMD
Increase seen in percentage of patients free from pain, from their most bothersome symptom at two hours
Findings seen in severely injured patients with a contraindication to prophylactic anticoagulation
Exposure to pH1N1 influenza vaccine in utero not linked to most pediatric health outcomes
In prospective cohort study, consuming 100 percent fruit juice also tied to increased cancer risk
Lifetime exposure to elevated systolic blood pressure may increase risk for major valvular heart disease
Rebates would have been paid directly to seniors in Medicare Part D program when they filled their Rx
Emotional recognition bias may partially mediate the link between IBD activity and depression
Minimum-volume standards could restrict care at many centers with better-than-expected outcomes
Mean reduction in weekly frequency of cluster headache attacks greater with galcanezumab versus placebo
Activities included reading books, using computers, social or craft activities, and playing games
Remdesivir, ZMapp monoclonal antibodies both appear to block growth of the Ebola virus strain
Findings based on patient reports, although effect greater in men
Nearly 25 percent of patients meet treatment criteria, but only 5 percent get prescription
Improvements in high-risk moms and babies seen with modest improvements in nutritional content
Findings based on U.S. county-level data, independent of opioid prescription rates
Incidence of herpes zoster decreased during median 21-month follow-up after autologous HSCT
Among opioid-naive patients, 8.4 percent of those who filled an initial opioid Rx had persistent use
Twofold higher risk for cancer seen for children, young adults with congenital heart disease
In large trial and literature review, benefit seen for depression but not anxiety symptoms
Risk assessment should consider infants born at ≥35 0/7 weeks and ≤34 6/7 weeks separately
Algorithms use data from EHRs to identify candidates for preexposure prophylaxis
Goals include disease prevention, switch to at-home dialysis, early transplants
A smaller number of new cases was reported than has been typical this spring
The rule, applying to any drug that costs more than $35 a month, was to take effect this week
Drug combination approved to treat patients who have failed at least five other treatments
Receiving more than average number of messages linked to increased probability of physician burnout
62 percent of reported cases of acute flaccid myelitis classified as confirmed
Cancer risk up for MS patients versus non-MS controls, especially in respiratory, urinary, CNS organs
FEV1:FVC of 0.70 not significantly different from optimal threshold, better than LLN threshold
Food insecurity also tied to measures of inflammation and stress in patients with diabetes
U.K. study also shows association between CP and osteoarthritis when adjusting for other factors
Rise in obesity since 1960s seen in both genetically predisposed, nonpredisposed people
Mortality decrease greater in systemic lupus erythematosus pregnancies than in non-SLE pregnancies
Negative school outcomes reduced after adding protective factors into same model as ACEs
Patients with a-fib and history of liver disease more often had major bleeding but no increase in SSEE
ADT exposure linked to subsequent Alzheimer disease diagnosis among elderly men at eight years
Lateral extended nasal island myocutaneous flap can bridge distances up to 1.8 cm
Significant improvements seen in action research arm test, grasp release test 24 months postsurgery
As a precautionary measure, Altaire is initiating the recall due to issues with product sterility
Relative Value Scale Update Committee overestimates time for original, revision replacements
Findings seen for adults who engaged in moderate-to-vigorous physical activity
Most had no significant effect on mortality, cardiovascular disease outcomes
Risk factors include prosthetic heart valve, community acquisition, monomicrobial bacteremia
However, 82 percent of survey respondents see benefits to vaccines
Data source may help link nursing home staffing, resident outcomes
History of drug misuse, depression did not necessarily diminish hypothetical prescribing rates
Mortality risk lower in patients with diabetes and depression who received antidepressants
Neonatal mortality steady from 38 to 41 weeks gestational age, significantly higher at 42 weeks
Those with disorders have higher rates of other conditions, Rx years before diagnosis
Active sex life linked to reduced motor, nonmotor burden and higher reported quality of life
Coma and/or CNS depression, seizures more common with single-drug synthetic cannabinoid exposure
303 the number needed to screen in extended follow-up of National Lung Screening Trial
California legislative, educational interventions tied to drop in kindergartners without up-to-date vaccination
Improvements in mean WOMAC Pain, Physical Function scores for osteoarthritis of knee or hip
2018 temporary order that tightened controls on fentanyl-like drugs expires in February 2020
Findings show higher service use among people with suspected mental health needs
Interleukin 6 levels at six hours postconcussion are significantly associated with symptom duration
While poor diet, weight gain seen among both sexes, males show greater adverse changes
Retail customers report decreases in prescriptions, over-the-counter meds due to effectiveness of cannabis
However, almost half of survey respondents have not taken antibiotics as prescribed in the past
Urine-derived extracellular vesicle RNA provides diagnostic, prognostic information in prostate cancer
New variables ID the sickest waitlist candidates with cystic fibrosis, chronic obstructive pulmonary disease
Higher rate of treatment failure for lung cancer patients with high Deep Profiler scores
Years after traumatic brain injury, patients still perform significantly worse on cognitive measures
Adding NfL to predictive score, including race and Framingham Stroke Risk Score, ups C-statistic
Evidence from 23 reviews could not be combined in meta-analysis; quality of evidence low
Higher percent trunk fat and lower percent leg fat linked to increased risk of cardiovascular disease
Women with incomes <$25,000 less often seek infertility care than those with incomes >$100,000
Greater organ-absorbed doses may be modestly positively associated with risk of solid cancer death
This is despite clinical guidelines calling for limiting sedation of patients on mechanical ventilation
Sponsors of the bill hope the tax will help keep the products out of the hands of teenagers
There are about 700 to 1,200 cases of necrotizing fasciitis reported each year in the United States
More must be done to combat false information about childhood vaccines being spread by 'anti-vaxxers'
Increased job fulfillment, decreased burnout seen for critical care physicians working seven-day rotations
Increased risk for several neonatal, postnatal outcomes for offspring exposed to maternal migraine
18 percent of all ED visits, 16 percent of in-network hospital stays have at least one out-of-network charge
Education-based approaches improve self-management behavior; psychosocial therapy approaches up QoL
Mental disorders interact with physical multimorbidity to increase odds of frequent ED visits
Adverse outcomes seen at birth and in preschool and school-aged children
More patients surviving to adulthood; management affected by scarcity of knowledge
Successful care environment includes clinician, staff training and inclusive practice policies
Findings show statin use tied to higher HbA1c values, with longer statin use tied to greater risk for diabetes
Protective association for LTPA persisted in all age, hypertension groups; was stronger for smokers
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Many healthcare-associated, community-onset urinary tract infections develop after being discharged
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Lower values for resorption end points at month two persisted to month 12, indicating reduced turnover
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Persistent low vitamin D from birth to early childhood linked to higher risk of elevated SBP from age 3 to 18
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Vessel scores based on machine learning model that uses data from coronary CT angiography
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Findings observed for acute respiratory infection in emergency departments and urgent care centers
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Risk-assessment tool uses troponin concentration at ED arrival, dynamic change during serial sampling
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Survival benefit not seen with ever use of metformin for pancreatic cancer-related diabetes
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Calculated tumor area is a novel, microscopic feature and a two-dimensional surrogate for tumor size
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Twenty-nine percent of grandparents report using other types of containers for prescription meds
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Some level of regret is common, but women are overwhelmingly satisfied with decision
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Nutrition-focused quality improvement program can reduce rates of hospitalization, health care use
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Combination of clinical and radiologic factors can reliably predict risk for incident lung cancer
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