Rheumatoid Arthritis Linked to Higher Risk for Type 2 Diabetes

RA linked to increased risk for developing diabetes; association remained in sensitivity analysis

Diagnoses of Common Conditions Declined in March to May 2020

Common mental health diagnoses reduced 50 percent; similar drops seen in circulatory system diseases, T2DM

HRRP Tied to Decrease in 30-Day Readmission Rates for COPD

But increase seen in 30-day risk-standardized postdischarge mortality rates for COPD patients

Performance of Commercial SARS-CoV-2 Ab Tests Varies

Performance highly dependent on time of sampling in head-to-head comparisons

Poorer Exercise Capacity Persists With Ventricular Septal Defects

Difference between patients with surgically repaired, unrepaired VSDs versus controls increased with age

Fertility Treatment Cancellations Due to COVID-19 Impact Mental Health

Several protective psychosocial factors can help women cope during the pandemic

Pupillary Light Reflex Metrics May ID Sports Concussion in Teens

Eight of nine metrics significantly greater among athletes with concussion versus healthy controls

One-Fifth of Those With SARS-CoV-2 Infection Asymptomatic

No significant differences seen in mean cycle threshold values for asymptomatic, symptomatic patients

ACIP Provides Recommendations on Meningococcal Vaccination

Vaccination with MenACWY recommended for adolescents aged 11 to 12 years with booster at 16 years

Median Age of COVID-19 Cases Declined in May to August in U.S.

In Southern U.S., increases in positive PCR tests in adults age 20 to 39 preceded those in adults ≥60

Survey: Rheumatic Diseases Pose Routine Challenges

Patient survey shows challenges with affordability, activity limitations, mental health

Public Awareness Low for Invasive Fungal Diseases

Awareness varies from 4.1 percent for blastomycosis to 24.6 percent for candidiasis

FDA Requiring Labeling Changes to Benzodiazepine Prescribing Information

Update to Boxed Warning must include risks for abuse, misuse, addiction, physical dependence, withdrawal reaction

Guidelines Updated for Managing Dyslipidemia to Cut CVD Risk

Moderate-dose statin therapy recommended for patients with 10-year CVD risk ≥12 percent

Cognition-Enhancing Supplements May Contain Unapproved Drugs

Five unapproved pharmaceutical drugs ID'd in supplements marketed to improve memory, cognition

Teens’ Mental Illness Treatment May Not Follow Guidelines

Variance in treatment occurs within and across ZIP codes, suggesting non-supply-side variables

Heavy Sugar-Sweetened Drink Intake Decreasing Overall in U.S.

Heavy SSB intake up for adults ≥60 years; no change seen for those age 40 to 59 years, non-Mexican Hispanics

Acute Kidney Injury Ups Risk for Death in COVID-19 Patients

Findings based on large study of hospitalized patients in New York City early in the pandemic

COVID-19 Risk in Assisted Living Similar to Nursing Homes

Assisted living communities with more minority residents have more COVID-19 cases

Measures of Central Adiposity Linked to All-Cause Mortality

Waist circumference, waist-to-hip ratio, waist-to-height ratio linked to increased all-cause mortality

Major Adverse CV Event Risk Reduced With SGLT2 Inhibitors

Risks for MACE, MI, cardiovascular death, heart failure, all-cause mortality lower versus DPP-4 inhibitors

Stroke ‘Alarm Clock’ Improves Acute Stroke Management Metrics

Time from door to completion of diagnostic work-up improved with feedback-demanding clock

Children’s Routine Care Plummets During Pandemic

Immunizations increased since May, but huge jump needed to make up for missed vaccinations since the spring

Chinese Company Says Its COVID-19 Vaccine Should Be Available in U.S. in Early 2021

If it passes final round of human tests, SinoVac will apply to the FDA to sell CoronaVac vaccine

United First U.S. Airline to Offer COVID-19 Testing for Passengers

Rapid test at airport provides results in about 20 minutes and will cost $250

U.S. COVID-19 Death Toll Hits 200,000 as Cases Climb in 22 States

IHME says COVID-19 is second-leading cause of death in the United States, after heart disease

As Flu Season Approaches, Clinicians Brace for Potential ‘Twindemic’

Reluctance, fear to leave home may impact the amount of people willing to receive the flu vaccine this year, expert tells HD Live!

Genetically Predicted BMI Increases Rheumatoid Arthritis Risk

Effect consistent across sensitivity analyses and comparable for men and women

CDC: Women More Likely to Experience Anxiety, Depression

Women are more likely to receive any mental health treatment, as are children aged 12 to 17 years

Risk for Autism Increased With Preterm, Postterm Birth

Risk increased for children born in weeks 22 to 31, 32 to 36, 43 to 44 versus 37 to 42 of gestation

Most People With SARS-CoV-2 Do Not Remain Asymptomatic

Secondary attack rate lower for contacts of people with asymptomatic versus symptomatic infection

Oral Steroids May Raise Risks for Diabetes, HTN, VTE in Children

But absolute risks for these complications still low among children receiving glucocorticoids

Negative Pressure Does Not Cut C-Section Infection Risk in Obese

Findings do not support routine use of prophylactic negative pressure wound therapy in obese women

Metformin May Slow Cognitive Decline in Seniors With T2DM

Cognitive decline slower, dementia risk reduced in seniors with diabetes receiving metformin

Fewer Women Aware of Heart Disease as Leading Cause of Death

Among U.S. women, decrease in awareness seen for all races/ethnicities, all ages except ≥65 years

Red Blood Cell Distribution Width, Mortality Tied in COVID-19

Elevated RDW and increase in RDW during hospitalization linked to increased mortality risk

SARS-CoV-2 Mortality Mainly Linked to Older Age, Comorbidity

Among U.S. veterans, obesity, Black race, Hispanic ethnicity, COPD, HTN not tied to COVID-19 mortality

>2.2 Million Women Live in Maternity Care Desert Status Areas

In addition, 4.8 million women of childbearing age live in counties with limited access to maternity care

Stricter Vaccine Approval Rules Coming From FDA

If approved by the White House, revised guidelines could be released as early as next week

J&J COVID-19 Vaccine Begins Final Stage of Clinical Trials

Phase 3 trials will include 60,000 people and be the largest for a COVID-19 vaccine in the United States

USPSTF Finds Evidence Lacking for Vitamin D Screening

Current evidence inadequate to determine benefits and harms of screening for vitamin D deficiency

AKI Occurs in 7 Percent of Those Hospitalized With COVID-19

Acute kidney injury linked to in-hospital mortality, even after adjustment for confounding variables

Rates of COVID-19 Infection Higher in Blacks, Hispanics

Disparity not explained by underlying medical conditions or where they live or receive care

1998 to 2016 Saw Rise in Alcohol Use Disorder Hospitalizations

During same period, in-hospital mortality for patients hospitalized with AUD decreased

Individuals With Diabetes Have Increased Risk for Falls

Risk for falls higher in adjusted analysis for individuals with type 1 and type 2 diabetes

Study Examines Effect of Cancer Treatment on COVID-19 Mortality

Highest 30-day mortality seen with cancer treatment one to three months before COVID-19 diagnosis

Pregnancy May Delay Onset of Multiple Sclerosis Symptoms

However, having more pregnancies not associated with later onset

Glucocorticoids Linked to Hospitalized Infection Risk in RA

Risk for hospitalized infections up for patients with RA receiving DMARDs with continued glucocorticoid use

Mental Illness Recognition Up in U.K. General Hospital Admissions

Diagnostic recording less accurate for those with minority ethnicity, married status, better health

Air Pollution May Raise Stroke Risk With Atrial Fibrillation

Findings account for neighborhood-specific pollution data, sociodemographic factors

Loneliness a Risk Factor for Type 2 Diabetes Mellitus

Findings independent of known diabetes risk factors, depression, living alone, social isolation

PrEP Prescribing Low in the U.S., Even Among HIV Care Providers

About half of survey participants recruited from HIV CME courses reported ever prescribing PrEP

Adverse Pregnancy Outcomes Tied to Later Atherosclerotic CVD

Findings remain when adjusting for standard risk factors, other adverse pregnancy outcomes

Rates of Recurrent MI Declined Among U.S. Women and Men

Decreases seen in rates of recurrent MI, recurrent CHD events, heart failure hospitalization

Perrigo Asthma Inhalers Recalled Due to Clog Risk

Some of the recalled albuterol sulfate inhalers stop working after several uses

COVID-19 Death Toll Nears 200,000 in the United States

Conceivable that death toll could reach 300,000 if Americans start to relax social distancing measures

AstraZeneca Releases COVID-19 Vaccine Trial Plans

Serious neurological illnesses have led the company to halt its trials twice

CDC Removes New COVID-19 Guidelines Just Days After Posting Them

Updated guidelines were posted Friday but removed Monday because they were posted in error

Many School Employees at Increased Risk for Severe COVID-19

Between 33.9 and 44.2 million of all adults with risk factors for severe COVID-19 have links to schools

Stress, Depressive Symptoms Up With Increasing COVID-19 Deaths

Exposure to COVID-19-related media, conflicting COVID-19 information in media linked to symptoms

Avelumab Prolongs Survival in Advanced Urothelial Cancer

Findings seen in patients with advanced, metastatic disease that did not progress with first-line chemo

Hip Implant Survival Tied to Implant Choice

Implant selection easier to change than technical skills or system factors, authors say

Peanut-, Tree Nut-Induced Anaphylaxis Up on Halloween, Easter

Increases in risk for anaphylaxis induced by unknown nuts, peanuts among Canadian children

Injuries Associated With Glass Tables Common in U.S.

56 percent of injuries in National Electronic Injury Surveillance System database due to faulty tables

Hostility Predicts Mortality in Acute Coronary Syndrome

More than half of patients scored as hostile; hostility predicts all-cause mortality but not ACS recurrence

Timing of Gender-Affirming Care Linked to Mental Health

Mental health worse with late pubertal stage, older age for youth presenting for gender-affirming care

Impact of Psoriasis Explored for Hospital Outcomes of Acute MI

Myocardial infarction may occur earlier in life in patients with psoriasis

Black Women Receive Less Timely Breast Cancer Treatment

Trend persists regardless of socioeconomic status

Inverted U-Shaped Link Seen for Sleep Duration, Cognitive Decline

Decline in global cognitive z-score faster for individuals with ≤4 hours, ≥10 hours of sleep nightly

Individuals With Autism at Risk for Other Health Conditions

Risk higher compared with the general population even after controlling for smoking, alcohol use, BMI

CDC: Adult Obesity Increasing, Tied to Worse COVID-19 Outcomes

Racial and ethnic disparities in obesity reported, with highest prevalence for non-Hispanic Blacks and Hispanics

Drug May Reduce Need for Ventilators in COVID-19 Patients

85 percent of study population was Hispanic, Black, Native American, other ethnic or racial minorities

Details Emerge on Unexplained Illness in AstraZeneca COVID-19 Vaccine Trial

Healthy 37-year-old woman 'experienced confirmed transverse myelitis' after receiving second dose of vaccine

Warning Issued on Potentially Deadly Mosquito-Borne Virus in Michigan

Suspected case of EEE in a resident of Barry County was announced earlier this week by state officials

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Botox for TMJ Disorder Does Not Affect Jaw Bone Density

Low-dose botulinum toxin injections for jaw, facial pain not linked to short-term bone changes

Older Adults Experiencing More Loneliness During Pandemic

However, many do report using technology to connect with friends and family

Depression Common Among Psoriasis Patients

Women, patients younger than 30 years have higher rates of depression

ATS Issues Recommendations for Noninvasive Ventilation in COPD

Use of nocturnal NIV suggested as well as usual care for patients with chronic stable hypercapnic COPD

Black Newborn Mortality Lower With Care From Black Doctors

However, racial concordance between mother and physician not tied to lower maternal mortality

Lifestyle Changes May Aid Cognitive Abilities

Cognition scores significantly higher for older adults experiencing cognitive decline assigned to an intervention

Lung Cancer Treatment Plans Changed Due to Pandemic

57 percent of patients receiving active treatment had at least one change in treatment plans

Coffee, Tea, Soda Tied to Higher Risk for Gastroesophageal Reflux

Consuming water, juice, milk not linked to increased risk for gastroesophageal reflux symptoms

Lower Proportion of Inpatients With COVID-19 Wear Glasses

Proportion of those wearing glasses daily for extended periods lower than for general population

Fetal Mortality Rate Higher for Black Versus White Mothers

Increased rate of fetal death in black mothers seen for deaths attributed to multiple causes

More Than Half of Pregnant Women With COVID-19 Asymptomatic

Prepregnancy obesity, gestational diabetes higher for pregnant women with COVID-19-linked illness

Meta-Analysis Links PTSD to Increased Dementia Risk

Risk up in veterans and general population, remains significant after exclusion of high-bias studies

COVID-19 Vaccine Distribution Would Begin Within 24 Hours After Approval

U.S. officials also said it is not clear when a vaccine might be available

Moderna May Know by November Whether COVID-19 Vaccine Is Effective

Company could have enough late-stage trial data by October to evaluate its efficacy

Elderly Social Isolation, Loneliness in COVID-19 May Lead to Cognitive Decline

Expert tells HD Live! that socialization of seniors in COVID-19 needs to be tailored to individual needs

Coffee Linked to Reduced Disease Progression, Death in CRC

Reductions in risk for overall, progression-free survival seen for those consuming two to three cups/day

Flu Activity Low in Southern Hemisphere in June to August 2020

Little flu circulation anticipated in Northern Hemisphere flu season with community mitigation measures

Transient Orthostatic Hypotension Common in Parkinson Disease

PD patients with history of orthostatic intolerance had more severe systolic BP decrease

Novel Risk, Protective Factors for Type 2 Diabetes Identified

Mendelian randomization study identifies insomnia as possible risk factor for type 2 diabetes

Adding Belimumab Improves Renal Outcome in Lupus Nephritis

Odds of primary efficacy renal response, complete renal response increased at week 104

Study Suggests Smoking Causes Fatal Subarachnoid Hemorrhage

Large, long-term twin study reveals link between smoking and subarachnoid hemorrhage

Hydrocortisone Early After Septic Shock Onset May Aid Outcomes

Days alive and free from vasopressors greater for initiation within 24 hours versus >48 hours

Survey: About Seven in 10 Adults Interested in COVID-19 Vaccine

Willingness to receive the vaccine lower among Black respondents

Substance Use Disorder Linked to Increased Risk for COVID-19

Increased risk especially strong for those with opioid use disorder, tobacco use disorder

EPA, DHA Supplementation Linked to Reduced Risk for MI, CHD

Significant reductions in risk seen for MI, fatal MI, and coronary heart disease events and mortality

Cancer Incidence Up for Adolescents and Young Adults

2007 to 2016 saw increase in overall cancer incidence in all age groups, mainly driven by thyroid cancer

PPI Use Is Negative Prognostic Marker in Urothelial Cancer

PPI use linked to significantly worse progression-free, overall survival in advanced urothelial cancer

Portable Low-Field MRI Allows Brain Imaging in ICU Patients

Feasibility of bedside brain MRI demonstrated in 50 patients admitted to neuroscience or COVID-19 ICUs

Vaccine Campaign Would Take Six to Nine Months to Curb COVID-19

First to be vaccinated would be those with health conditions that make them vulnerable to severe illness, death

ADHD Prevalence Higher Among Blacks Than U.S. Population

Authors say results show need to up assessment, make accurate diagnoses, give culturally appropriate care

Ultrasound Ablation Offers Option for Some With Prostate Cancer

Bilateral prostate cancer at diagnosis was sole predictor of Grade Group 2 or greater recurrence

Characteristics ID’d for Under 21s With SARS-CoV-2-Linked Deaths

Teens and young adults, those with underlying medical conditions overrepresented among decedents

New Drug Shows Promise in Preventing Severe COVID-19

Drug is monoclonal antibody, a man-made copy of antibody produced by a recovered COVID-19 patient

Low-to-Moderate Drinking May Protect Cognition During Aging

However, results show significant racial difference, with stronger association for Whites

Pacemaker Need Higher in Patients With Type 2 Diabetes

Older age, longer diabetes duration, higher HbA1c tied to increased risk for pacemaker transplantation

Obstructive Sleep Apnea Tied to Worse Bone Health

Findings strongest for development of vertebral fracture

Spironolactone Not Tied to Breast Cancer Recurrence

Drug can be used for alopecia treatment in breast cancer survivors

Many Doctors Misinformed About Nicotine’s Risks

Less than one-third of doctors correctly agree that nicotine directly contributed to birth defects

Better Cardiovascular Health Linked to Lower Incident HTN

Each 1-point increase on the Life's Simple 7 score linked to 6 percent lower risk for incident HTN

Financial Toxicity Common in Patients With Multiple Sclerosis

Many MS patients report lifestyle-altering behaviors or care nonadherence due to financial burden

Severely Obese Heart Donors Not Tied to Adverse Transplant Outcomes

Short-term outcomes for recipients similar for heart transplants from donors with, without severe obesity

Lipid-Rich Necrotic Core Linked to Psoriasis Severity

Patients on biologic therapy had reduction in lipid-rich necrotic core at one year

Factor V Activity Significantly Increased in Severe COVID-19

Rates of DVT/PE significantly higher for patients with COVID-19 and elevated factor V activity

Levodopa Benefits Neovascular Age-Related Macular Degeneration

Levodopa is safe and well-tolerated, improves visual outcomes, and delays anti-VEGF treatment

Poll: Most Americans Do Not Trust Trump’s COVID-19 Vaccine Comments

More than half of adults say they do not trust the president's vaccine comments

Eflornithine + Sulindac Shows No Benefit in Adenomatous Polyposis

Incidence of disease progression not significantly lower with combo versus either drug alone

Early Age at Menarche Tied to Worse Cardiovascular Health

Women with later age at menarche have higher odds of ideal cardiovascular health

Office Dismissal Policy for Families Refusing Vaccines Common

Office policies for dismissal of families more common than physician's dismissal behavior

About 20 Percent of Women Avoid Pregnancy Due to Migraine

72.5 percent of women who avoided pregnancy believed that migraine would be worse in pregnancy

Intensive Therapy for HTN Tied to Drop in Orthostatic Hypotension

Meta-analysis of trials shows risk for OH reduced with intensive blood pressure treatment for hypertension

Darolutamide Boosts Survival in Nonmetastatic Prostate Cancer

Risk for death significantly lower versus placebo in nonmetastatic, castration-resistant prostate cancer

Antipsychotic Rx Still Common With Intellectual Disabilities

Also, sharp increase seen in antidepressant prescriptions in 2014 versus 2004

Handgrip Strength May Help Predict Risk for Type 2 Diabetes

Handgrip measures + conventional risk factors improve risk assessment, especially in women

Curcuma longa Extract Improves Knee Pain in Osteoarthritis

CL improved pain but did not change effusion-synovitis volume or cartilage composition

Pediatric Ophthalmologists Hit Hard Financially by COVID-19

Many practices closing, declaring bankruptcy, limiting Medicaid patients in response

Clinical Score Predicts Poor Pain Control After Spine Surgery

Prediction model based on seven variables, including younger age, preoperative daily opioid use

Study Examines Diet and Risk for Rheumatoid Arthritis in Women

Adherence to Mediterranean diet might lower rheumatoid arthritis risk in female ever-smokers

HPV Vaccination Rates Increasing Among 15-Year-Olds

Proportion of one- or two-dose HPV vaccination increased from 2011 to 2017; still falling short of goals

24.4 Percent of U.K. Health Care Workers Positive for SARS-CoV-2

Seroprevalence varies for health care workers in different departments; rate lower for ICU staff

Vaccine Confidence Recently Increased in Some of Europe

Confidence in importance, safety, effectiveness of vaccines down in Afghanistan, other countries

Canada Reports No New COVID-19 Deaths for First Time in Six Months

As of Saturday, there had been 137,676 COVID-19 cases and 9,214 deaths from the illness in Canada

AstraZeneca COVID-19 Vaccine Trial Restarts

Trial was halted after a suspected adverse reaction in a patient

Effectiveness of Inhaled COVID-19 Vaccines to Be Studied

Trial will test responses of 30 adults when they inhale vaccine droplets in their mouths

Baricitinib May Shorten Recovery Time in Hospitalized COVID-19 Patients

Adding anti-inflammatory drug to remdesivir seems to shorten time to hospital discharge

Among Hospital Patients, Children Less Likely to Carry SARS-CoV-2

Among those without COVID-19 symptoms, children less likely than adults to test positive for SARS-CoV-2

BP Control Down in the United States From 2013-2014 to 2017-2018

BP control, awareness, treatment down in adults aged 40 to 59 years from 2009-2012 to 2015-2018

NIH Launches Clinical Trials of Antithrombotics for COVID-19

Adaptive design allows evaluation of various doses, types of blood thinners in outpatients, inpatients

Coronary Artery Calcium Score IDs Coronary Heart Disease Risk

Predictive value for coronary heart disease risk similar across sex and racial groups

One or More Opioids Involved in ~80 Percent of OD Deaths

At least one potential opportunity for prevention intervention for 62.7 percent of overdose deaths

Workplace Sexual Harassment Tied to Suicide Risk

Association accounted for sociodemographic and work characteristics plus baseline health

Depression Worsens Over Time in Caregivers of Partners With Dementia

Symptoms sustained regardless of whether the diagnosis was less than or more than two years before

Telepsychology Use Up 12-Fold in the U.S. During Pandemic

However, adoption of telepsychology has varied according to individual and practice characteristics

Psychological Response to COVID-19 Affects Pregnancy Stress

Pregnant women most commonly report psychological responses of fear and depression

Predictors of Transition to Adult Rheumatology Care Explored

Insurance coverage, referral from pediatric rheumatologist predict shorter time to adult visit

Pneumothorax Reported as Complication of COVID-19

Higher incidence seen among men; survival at 28 days lower for those 70 years of age or older

Florida Teen Dies From Brain-Eating Amoeba

Naegleria fowleri can get into the brain when contaminated water enters the nose

Weight Stigma May Predict Binge Eating During the Pandemic

Young adults with previous weight stigma at greater risk for maladaptive eating, regardless of weight

COVID-19 Suspected for Surge in Medical Visits at End of 2019

Excess seen for visits with cough in outpatient clinics, ED; hospitalizations with acute respiratory failure

Physician’s Briefing Weekly Coronavirus Roundup

Here is what the editors at Physician's Briefing chose as the most important COVID-19 developments for you and your practice for the week of...

Smokeless Tobacco Poses Global Health Burden

Greatest burden of smokeless tobacco-related disease found in South and Southeast Asia

Modafinil in Early Pregnancy Not Tied to Congenital Malformations

Large birth registry study conducted in Norway and Sweden did not show link to major malformations

Some Doctors Not Following Guidelines for Diagnosing HTN

Most providers rely on clinic BP measurements; almost all use clinic BP threshold of 140/90 mm Hg

Lowering Urine Protein Aids Renal Function in Rare Kidney Disease

Reducing proteinuria slows decline in kidney function in those with focal segmental glomerulosclerosis

Rates of Ambulatory Heart Failure Steady From 2001 to 2016

Greatest disparities seen between Black and White adults aged 35 to 64 years

Enhanced Recovery Approach Aids Cesarean Birth Outcomes

Benefits of enhanced recovery after surgery program include decreases in opioid use, length of stay, and costs

Future Cardiovascular Event Risk Up With High BP in Young Adults

Graded progressive link seen between categories of blood pressure and increased risk for CV events

Increases in Suicide Rates in Young Adults From 2000 to 2018

Suicide rates for those aged 10 to 24 statistically stable from 2000 to 2007 then increased to 2018

E-Cigarette Use Increased Significantly From 2017 to 2018

From 2016 to 2018, there was also an increase in daily use, sole e-cigarette use

Time Span of Football Play Not Linked to Concussion Recovery

Age of first exposure to playing football not related to recovery from a college football concussion

Time to Decannulation Shorter if Based on Suctioning Frequency

Suctioning frequency plus continuous oxygen better indicator in critically ill with tracheostomy tube

Nosocomial COVID-19 Rare During Height of Pandemic

Among patients not hospitalized for COVID-19, 0.1 percent tested positive within 14 days of discharge

Inflammatory Bowel Disease Tied to Subsequent Rhinosinusitis

Risk for developing chronic rhinosinusitis higher for patients with IBD, especially ulcerative colitis

CDC: Nearly 800 U.S. Children Have Developed COVID-19-Related Condition

Multisystem inflammatory syndrome in children also associated with 16 deaths reported in 42 states

NAMS Updates Guidance for Genitourinary Syndrome of Menopause

GSM is underdiagnosed and undertreated, but symptoms can be managed effectively in most cases

Controlled BP Down Among U.S. Adults With HTN After 2013–2014

Controlled BP more likely among those aged 45 to 64 years, less likely for those aged 75 years or older

Widespread Avoidance of Medical Care Found Due to COVID-19 Concerns

Prevalence of care avoidance higher for caregivers, those with underlying conditions, disabilities

Middle, High School Students Mainly Use Flavored E-Cigarettes

Proportion of disposable product e-cigarette sales increased during September 2019 to August 2020

Few High-Grade Soft Tissue Sarcoma Patients Receive Chemo

Percentage of STS patients receiving chemo driven by factors such as tumor size, income, facility type

Poverty-Stricken Adults More Likely to be Calcium-, Vitamin D-Deficient

Data suggest that nutrient deficiencies affect osteoporosis risk more for poverty-stricken men versus women

Considerable Adverse Outcomes Reported for Young Adults With COVID-19

Young adults hospitalized with COVID-19 have substantial rate of adverse outcomes; 2.7 percent died

Moderate, Heavy Drinking Linked to Increased BP, HTN in T2DM

Odds of elevated blood pressure and stage 1, 2 hypertension increased with moderate drinking

Shift Seen to Newer Agents to Treat Psoriasis

Biologics and small molecule inhibitors increasingly used for treatment of newly diagnosed psoriasis

Child Hospital, ICU Admission Rates Similar for COVID-19, Flu

But more clinical symptoms reported at the time of diagnosis for children with COVID-19 versus flu

Increase Seen in Hydroxychloroquine Rx by Nonroutine Specialists

New Rx increased 80-fold among specialists who do not typically prescribe these medications

Insurer, Insured Costs for HIV PrEP Rising in the United States

2014 to 2018 saw increase in estimated third-party, out-of-pocket payments per 30 TDF-FTC tablets

USPSTF: Evidence Lacking for Screening Elders for Hearing Loss

Evidence insufficient for assessing benefits and harms of screening in older adults without symptoms

Financial Strain Tied to Higher Risk for Suicide Attempts

Variables of debt, housing instability, unemployment, low income together increase risk 20-fold

Early Therapy for Rheumatoid Arthritis May Slow Heart Disease

RA treatment response does not appear to impact improvement in vascular stiffness

Pandemic Threatens Gains in Reducing Preventable Childhood Deaths

Many countries experiencing disruptions in childhood checkups, vaccinations, malnutrition programs

New COVID-19 Test Provides Results in 15 Minutes

Test correctly diagnoses infection 90 percent of the time and a negative result 100 percent of the time

Clinical Trial of AstraZeneca COVID-19 Vaccine Paused After Illness

Company investigating whether the illness may be a side effect of the vaccine

More Than Half a Million U.S. Children Already Infected With COVID-19

There were 70,630 new child cases reported between Aug. 20 and Sept. 3

Weight Gain Pattern Early in Life May Affect Later Lung Function

Children with early accelerated BMI gain have higher lung function at age 7 years

Respiratory, Lung Cancer Death Up Even With Low-Intensity Smoking

Risks for respiratory and lung cancer mortality increased for those smoking <10 cigarettes per day

Drug Companies Say Ethical, Scientific Standards Will Be Followed in Making COVID-19 Vaccines

The pledge issued Tuesday is meant to increase public confidence in any approved vaccines

CYP2C19 Genotyping May Aid Antiplatelet Prescribing

Benefit only seen for composite outcome, not for major or minor bleeding incidents

Median of 36 Days Found From COVID-19 Symptom Onset to Viral Clearance

Slight increase in time from symptom onset to viral clearance seen with increasing age, disease severity

High Coronary Artery Calcium + Diabetes Even Riskier for Women

In adults with diabetes, high CAC score predicts CVD, total mortality more strongly in women than in men

Seizures During Menstrual Cycle Tied to Drug-Resistant Epilepsy

History of a psychiatric condition, seizure types also linked to drug resistance

Prolonged Viral Shedding Seen in Children Positive for SARS-CoV-2

Median duration of viral shedding 19.5 days; median of 18 days found from RT-PCR positivity to seropositivity

Surgery May Be Viable Option for Treating Obstructive Sleep Apnea

Palatal and tongue surgery reduces apnea, hypopnea events in patients with OSA who fail routine therapy

Four Studies Indicate Benefits of Steroids for COVID-19

Three randomized trials and a meta-analysis show benefits for critically ill patients, severe COVID-19

AKI Common in Hospitalized Patients With COVID-19

AKI occurred in 46 percent of hospitalized patients, linked to increased risk for in-hospital mortality

Factors Clarify Racial Disparity in Prostate Cancer Survival

Education, median household income, and insurance status contribute most to racial disparity in the U.S.

States Should Prepare for COVID-19 Vaccine by Nov. 1

U.S. Surgeon General said a COVID-19 vaccine is possible, but not probable, by Nov. 1